journal
Journals American Journal of Dermatopat...

American Journal of Dermatopathology

https://read.qxmd.com/read/38513131/cutaneous-collagenous-vasculopathy-a-short-case-series-and-literature-review
#1
JOURNAL ARTICLE
Anahita T Kodali, Meghana Agni, Arthur Marka, Denise Aaron, Jeffrey M Cloutier, Aravindhan Sriharan
Cutaneous collagenous vasculopathy (CCV) is a rare and idiopathic microangiopathy of superficial dermal blood vessels. There have been 75 cases described in the literature to date, not including the current report; however, given its clinical similarity to other primary telangiectasias, it is likely to be underreported and underdiagnosed. Here, we describe the clinical and histological features of 2 patients we newly diagnosed with CCV. Both generally fit the profile of prior cases and confirm previously described associations-they both are older White women, have rashes on their lower extremities, and have conditions and medications that are common among other reported cases...
March 19, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38513122/melanocytic-acral-nevus-with-intraepidermal-ascent-of-cells-five-cases
#2
JOURNAL ARTICLE
Angel Gabriel Boscolo Ruivo, Marcel Arakaki Asato, Luis Fernando Ferrari, Denise Rodrigues Poletto, Roberto Coelho Okida, Jose Candido Caldeira Xavier-Júnior
No abstract text is available yet for this article.
March 19, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38513120/melanocyte-density-in-the-diagnosis-of-melanoma-in-situ-in-sun-damaged-skin
#3
JOURNAL ARTICLE
Rieke Löper, Michael P Schön, Christina Mitteldorf
Histologic differentiation between melanoma in situ in chronically sun-damaged skin (CSDS) [lentigo maligna (LM)] and CSDS without malignancy is difficult because signs of melanocyte activation and proliferation are found in both. A potentially reliable and quantifiable criterion is melanocyte density (MD). Here, we evaluated whether and to what extent MD allows the distinction between LM and CSDS, which is particularly relevant for the evaluation of borderline cases and surgical margins.Articles assessing MD in LM and/or CSDS were evaluated in a systematic review...
March 19, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38513115/onychocytic-matricoma-a-clinical-dermoscopic-and-pathological-analysis-of-14-cases
#4
JOURNAL ARTICLE
Christophe Perrin, Michael Coutts, Feriel Boukari, Damien Ambrosetti
Onychocytic matricoma (OCM) is a benign neoplasm of the nail matrix. Only 18 cases of this tumor have been reported in the literature to date. We retrospectively analyzed the clinical features of 14 patients with OCM. The most common clinical feature was longitudinal xanthopachyonychia (n = 9), followed by longitudinal leukopachyonychia (=3) and longitudinal pachymelanonychia (n = 2). The most common clinical findings identified following dermoscopy and analysis at high magnification of classical photographs were free-edge thickening of the nail plate without pitting (n = 14), longitudinal ridging (n = 7), round white clods (n = 7), white dots (n = 7), and filiform hemorrhages (n = 7), followed by oval and linear white clods (n = 5), fuzzy lateral border (n = 5), and red-purple blood clods (n = 3)...
March 19, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38513130/chronic-radiation-dermatitis-secondary-to-narrow-band-ultraviolet-b-therapy-in-a-patient-with-primary-cutaneous-cd8-t-cell-lymphoma-with-cytotoxic-granules
#5
JOURNAL ARTICLE
Mia P Edelson, Jane J Gay, Robert W Thiel, Douglas J Grider
Conventional therapies for CD8+ cutaneous T-cell lymphoma include topical steroids, topical nitrogen mustard, topical bexarotene, ultraviolet B therapy, psoralen and ultraviolet A therapy, local radiotherapy, and interferon alfa; however, these treatments are often found to be ineffective. Presented is a case of CD8+ cutaneous T-cell lymphoma with near-complete response to narrow-band ultraviolet therapy because of chronic radiation dermatitis initially believed to be possible progression of a CD8+ cutaneous epidermotropic cytotoxic T-cell lymphoma...
March 12, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38513123/cocaine-induced-plasma-cell-orificial-dermatomucositis-a-more-accurate-descriptive-term-for-a-clearly-dermatological-entity
#6
JOURNAL ARTICLE
Angel Fernandez-Flores, José Manuel González Montero
Although the involvement of the nasal passages and nasal septum in cocaine users has been known for decades, a new presentation affecting the nostrils and upper lip with an inflamed appearance has recently been documented. The authors who identified this presentation termed it "cocaine-related plasma cell mucositis" due to the abundance of plasma cells in the infiltrate. In this article, we present a second case and emphasize the dermal involvement of the lip, leading us to consider the condition as a genuine dermatomucositis...
March 12, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457743/a-case-of-early-morphea-mimicking-hypopigmented-mycosis-fungoides-in-a-pediatric-patient
#7
JOURNAL ARTICLE
Michelle D Colbert, Molly J Youssef, Julia S Lehman, Emma F Johnson
No abstract text is available yet for this article.
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457692/cutaneous-hydrophilic-polymer-embolism-an-important-and-overlooked-clinical-entity
#8
JOURNAL ARTICLE
Kimberly Pei Rui Chan, Joyce Siong See Lee, Joel Hua Liang Lim
Hydrophilic polymer embolism from vascular medical devices is an underrecognized clinical entity that can cause deleterious end-organ ischemia and culminate in mortality. This is concerning as we are in the era where minimally invasive procedures are commonplace. Diagnosis is often made retrospectively after obtaining histopathological tissue samples showing endoluminal, cerebriform, amorphous, anucleate, basophilic, nonrefractile, nonpolarizable foreign body material. We detail 2 more cases of cutaneous hydrophilic polymer embolism to underscore its salient clinicopathological features and increase awareness of this important iatrogenic entity...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457690/metastatic-tonsil-squamous-cell-carcinoma-an-important-consideration-in-the-differential-diagnosis-of-malignant-basaloid-neoplasms-in-the-skin-case-report-and-review-of-the-literature
#9
JOURNAL ARTICLE
Bradley T Thigpen, Ronald B Johnston, Alessio Giubellino, Diana O Mogrovejo, Ashok R Jethwa, Willmar D Patino
Malignant basaloid neoplasms of the skin are frequent, and their accurate diagnosis holds paramount importance for treatment and prognosis. However, these neoplasms can present diagnostic challenges because of their extensive differential diagnosis, which encompasses cutaneous metastasis among many other possibilities. We present a case of a 74-year-old man with a history of p16-positive palatine tonsil squamous cell carcinoma (SCC) treated with surgery and adjuvant radiation with no prior evidence of recurrence who presented to the dermatologist with 2 chin papules...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457688/perineural-inflammation-as-a-novel-feature-in-lichen-sclerosus-a-case-series-of-histologic-and-clinical-features
#10
JOURNAL ARTICLE
Joshua Del Papa, Aine Celestina Pucchio, Mark Schneider, Ami Wang
Lichen sclerosus (LS) is a frequently encountered inflammatory skin disorder characterized by whitened, atrophic patches that can cause pain and pruritus. The underlying cause of this condition remains unknown. Primarily affecting the genital area, this condition carries an increased risk of developing cutaneous cancers and frequently co-occurs with autoimmune disorders. Our retrospective study aimed to explore histologic features of LS, with a particular focus on a newly established finding and its potential implications...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457687/comparison-of-2-t-cell-receptor-%C3%AE-clonality-assays-on-skin-biopsies-suspicious-for-mycosis-fungoides
#11
JOURNAL ARTICLE
Stan Miller, Travis Vandergriff, Heather Woodworth Goff, Jing Xu, Dwight Oliver
PCR-based fragment analysis of the T-cell receptor (TCR) gene is used extensively in diagnostic labs to assess clonality in T-cell populations in multiple tissue sites. Of the numerous TCR assays that have been reported, studies assessing use on biopsies suspicious for mycosis fungoides specifically are lacking. We compared clonality findings from a previously run 2-tube/2-fluorochrome dye assay to a redesigned 1-tube/1-fluorochrome dye assay on formalin-fixed skin biopsies. Overall, the accuracy of the 2-tube assay was marginally better (75...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457686/soluble-isoform-of-cd155-is-elevated-in-basal-cell-carcinoma
#12
JOURNAL ARTICLE
Jesus Ivan Martinez-Ortega, Elvis Martinez-Jaramillo, Mary Fafutis Morris
No abstract text is available yet for this article.
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457684/diagnostic-validation-of-anti-tox-antibody-for-early-stage-mycosis-fungoides-through-digital-analysis-of-tissue-samples
#13
JOURNAL ARTICLE
Ignacio Pinilla-Pagnon, Rosa Rojo-López, Ignacio Coll-Orduña, Adrián Nogales-Moro, Montserrat Chao-Crecente
Mycosis fungoides (MF) has become one of the most difficult diagnostic challenges for both dermatologists and dermatopathologists because its clinical presentation and microscopic findings may mimic benign reactive processes, specifically those displaying histopathological features of interface dermatitis. The goal of our study was to prove with digital scanning and automated sample methodology through algorithmic analysis, combined with the utility of TOX marker a more precise, faster, and objective evaluation of each sample...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457683/extranodal-follicular-dendritic-cell-sarcoma-presenting-on-the-skin
#14
JOURNAL ARTICLE
Rosario Agüero, Francisca Reculé, Jaime Pérez, Alex Castro
Follicular dendritic cell sarcoma is a rare intermediate-grade malignancy characterized by a proliferation of ovoid to spindle-shaped cells with morphologic and immunophenotypic features similar to normal follicular dendritic cells. It may develop in lymph nodes or extranodal sites. Its presentation in extranodal tissues is a diagnostic challenge. It requires a high index of suspicion because follicular dendritic cell markers are not included in the routine immunohistochemical panels used for differential diagnosis...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457682/lichen-planus-pemphigoides-induced-by-camrelizumab-in-combination-with-lenvatinib
#15
JOURNAL ARTICLE
Xiang Zhang, Jun Wang, Huiying Wang, Xiaoming Qin, Ruzhi Zhang
No abstract text is available yet for this article.
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457681/berep4-negative-basal-cell-carcinoma-an-immunophenotype-not-to-forget
#16
JOURNAL ARTICLE
Douglas W Murray, Robert W Thiel, Mariana A Phillips, Douglas J Grider
Basal cell carcinoma (BCC) is the most common cancer worldwide. Although not typically metastatic, BCC can be locally destructive. BerEP4 is an antibody against CD326, an epithelial cell adhesion molecule (EpCAM) that is expressed on epithelial progenitor cells and carcinomas. BerEP4 has been reported to have a 100% positive sensitivity in basal cell carcinomas, but a much lower sensitivity for a variety of other carcinomas, including clear cell renal cell carcinoma and metastatic renal cell carcinoma. A 74-year-old woman presented with a BerEP4-negative, but anti-renal cell antibody-positive BCC, and the stark clinical implications of misdiagnosis...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457673/perineural-infiltration-a-comprehensive-review-of-diagnostic-prognostic-and-therapeutic-implications
#17
JOURNAL ARTICLE
Juan Torre-Castro, Elisa Ríos-Viñuela, Inmaculada Balaguer-Franch, Ignacio Díaz de Lezcano, Ángel Aguado-García, Laura Nájera, Dolores Suárez, Luis Requena
Perineural infiltration refers to a neoplastic cell involvement in, around, and through the nerves. It is considered as one of the neoplastic dissemination pathways. Thus, its identification is crucial to establish the prognosis of some malignant skin neoplasms, such as squamous cell carcinoma, and explains the locally aggressive behavior of cutaneous neoplasms, such as microcystic adnexal carcinoma. We have conducted a review of malignant and benign skin tumors in which perineural infiltration has been described, and we also discuss some histopathological findings that may simulate perineural infiltration...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457672/diagnostically-challenging-multifocal-penile-epithelioid-hemangioma-successfully-treated-with-doxorubicin-hydrochloride
#18
JOURNAL ARTICLE
Marwa M Fawzi, Galal El Anany, Mohamed M Abdelraouf, Amira Elbendary
Epithelioid hemangioma (EH), also known as angiolymphoid hyperplasia with eosinophilia, is an unusual vascular proliferation that tends to manifest in the head and neck region. Its occurrence on the penis is rare, with only scarce reported cases in the literature. The histopathological examination of this condition poses a challenge because it shares similarities with other entities, such as epithelioid hemangioendothelioma, epithelioid angiosarcoma, cutaneous epithelioid angiomatous nodule, or Kaposi sarcoma (KS)...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457670/mpox-case-presenting-with-genital-lesions-and-proctitis
#19
JOURNAL ARTICLE
Yazan Alhalaseh, Mitul B Modi, Sandra Haddad, Adam Souchik, Jodi J Speiser, Razan Massarani-Wafai, Madhu Dahiya
Monkeypox (Mpox) is a zoonotic Orthopoxvirus of the Poxviridae family, endemic to Africa. In August 2022, the US government declared it an emergency because of the worldwide spread. Traditionally, Mpox infection spreads through contact with infected animals. However, the 2022 outbreak Centers for Disease Control and Prevention (CDC) data note that 94% of cases had recent male-to-male sexual or close intimate contact, suggesting a novel sexual transmission. In this article, we report a 39-year-old HIV-positive man presenting with a diffuse cutaneous rash, perianal pain, and bloody stool of 2-week duration...
March 8, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354379/gorlin-like-phenotype-in-a-young-girl-with-a-de-novo-ptch2-variant-mutation-of-uncertain-significance
#20
JOURNAL ARTICLE
Mar Garcia-Garcia, Sergio García-González, Clara Cabañuz, Lucía Prieto-Torres
Gorlin syndrome, also known as basal cell nevus syndrome, is an autosomal dominant genetic disorder that predisposes humans to tumors. In most cases, this syndrome results from inactivating mutations in the patched homologue 1 gene. Basal cell carcinomas are one of the main characteristics of this syndrome and serve as a major diagnostic criterion. Gorlin syndrome shows a variable phenotype, and recently, other less common mutations in the suppressor of fused homologue or patched homologue 2 genes have been documented in individuals with this syndrome...
February 7, 2024: American Journal of Dermatopathology
journal
journal
27817
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.