journal
https://read.qxmd.com/read/38657993/the-immunologic-abnormalities-in-patients-with-paroxysmal-nocturnal-hemoglobinuria-are-associated-with-disease-progression
#21
JOURNAL ARTICLE
Guanrou Wang, Mengting Che, Lijie Zeng, Hui Liu, Liyan Li, Zhaoyun Liu, Rong Fu
OBJECTIVES: To suggest the presence of a hyperimmune state in patients, and indicate that immune system attack on glycosylphosphatidylinositol (+) (GPI+ ) cells while escaping GPI- cell immunity. METHODS: We retrospective the immune cell subtypes in peripheral blood from 25 patients visiting Tianjin Medical University General Hospital, Tianjin, China, with classical paroxysmal nocturnal hemoglobinuria (PNH) and 50 healthy controls. RESULTS: The total CD3+ and CD3+ CD8+ cell levels were higher in patients with PNH...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657992/the-evolvement-of-breast-cancer-therapies-what-we-have-done-and-where-all-these-head-off
#22
REVIEW
Ika Nurlaila, Sabar Pambudi
Although, from a therapeutic standpoint, breast cancer (BC) is considerably well-characterized, it still leaves puzzling spots. The Her-2+/PR+/ER+ BC can benefit from the mainstays of anticancer therapy and immunotherapy and overall have a better prognosis. Triple-negative BC, due to the concomitant absence of Her-2/PR/ER receptors, is more challenging and necessitates different strategies. It has been learned that the mainstay anti-BC therapies were initially designed to demolish as many cancer cells as they possibly could...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657991/inappropriate-laboratory-test-utilization-in-outpatient-tertiary-care-implications-for-value-based-healthcare
#23
JOURNAL ARTICLE
Nouf F Almasoud, Mohammed A Aldosari, Ahmed S Mahmoud, Yaser A Alendijani, Abdullah H Alkhenizan
OBJECTIVES: To assess the rate of inappropriate repetition of laboratory testing and estimate the cost of such testing for thyroid stimulating hormone (TSH), total cholesterol, vitamin D, and vitamin B12 tests. METHODS: A retrospective cohort study was carried out in the Family Medicine and Polyclinic Department at King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. Clinical and laboratory data were collected between 2018-2021 for the 4 laboratory tests...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657990/risk-factors-for-severe-bronchopulmonary-dysplasia-in-a-chinese-cohort-of-very-preterm-infants
#24
MULTICENTER STUDY
Jing Huang, Wei Shen, Fan Wu, Jian Mao, Ling Liu, Yanmei Chang, Rong Zhang, Xiuzhen Ye, Yinping Qiu, Li Ma, Rui Cheng, Hui Wu, Dongmei Chen, Ling Chen, Ping Xu, Hua Mei, Sannan Wang, Falin Xu, Rong Ju, Zhi Zheng, Xinzhu Lin, Xiaomei Tong
OBJECTIVES: To examine the risk factors for severe bronchopulmonary dysplasia (BPD) in a cohort of very preterm infants (VPIs) in China, as BPD is common among VPIs and associated with a high mortality rate. METHODS: In this multicenter retrospective study, medical records from infants with BPD born at gestation age (GA) of <32 weeks with birth weight (BW) of <1,500 grams (g) in 7 regions of China were included. The cohort was stratified into different BPD severity groups based on their fraction of inspired oxygen requirement at a modified GA of 36 weeks or post discharge...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657989/does-worsening-metabolic-syndrome-increase-the-risk-of-developing-cancer
#25
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657988/outcome-of-pregnant-women-admitted-to-critical-care-unit-with-confirmed-severe-covid-19-a-center-experience
#26
JOURNAL ARTICLE
Amani AlJohi, Ahmad Alohali, Saffanah Alsaeed, Hussam M Sakkijah, Dalia A Obeid
OBJECTIVES: To explore the traits and risk factors of pregnant women admitted to intensive care units (ICUs) with COVID-19. Moreover, the study classifies outcomes based on differing levels of required respiratory support during their intensive care stay. METHODS: This retrospective and descriptive study included all pregnant women with COVID-19 admitted to the adult critical care unit at a specialized tertiary hospital in Riyadh, Saudi Arabia. Between January 2020 and December 2022...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657987/association-of-abo-rh-d-and-kell-blood-groups-with-transfusion-transmitted-infections-among-blood-donors-from-the-asir-region-saudi-arabia-a-retrospective-observational-study
#27
JOURNAL ARTICLE
Ahmad A Shaikh, Hassan M Alqasem, Yahya A Alshubruqi, Sultan Z Alasmari, Mohammed H Makkawi
OBJECTIVES: To evaluate the association between transfusion-transmitted infections (TTIs) and ABO, Rh-D, and Kell blood systems among blood donors. METHODS: This was a retrospective study of 10,095 donors who visited the Blood Bank at Asir Hospital, Abha, Saudi Arabia. Data including demographic information, ABO, Rh-D, and Kell blood groups, and serological and molecular test results of TTIs (the TTIs were obtained from each donor's records). Chi-squared and Fisher's exact tests were employed to establish possible associations between blood groups and TTIs...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657986/caprini-versus-padua-venous-thromboembolism-risk-assessment-scores-a-comparative-study-in-hospitalized-patients-at-a-tertiary-center
#28
COMPARATIVE STUDY
Nora Trabulsi, Abdulmajeed M Khafagy, Lenah S Alhazmi, Abdullah M Alghamdi, Abdulmajeed A Alzahrani, Mohanned M Banaamah, Ali Farsi, Alaa Shabkah, Ali Samkari, Marwan Al-Hajeili, Ahmed Abduljabbar, Mohammad Wazzan
OBJECTIVES: To assess and compare the Caprini and Padua risk assessment models (RAMs) for predicting venous thromboembolism (VTE) in hospitalized patients. METHODS: We retrospectively reviewed 28 VTE and 450 non-VTE patients hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, in 2019. Their baseline medical, demographic, and radiological reports were recorded. We compared Caprini scores (defined at admission) and Padua scores (calculated retrospectively) for their ability to predict VTE...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657985/what-factors-contribute-to-differences-in-cervical-cancer-screening-in-rural-and-urban-community-health-centers
#29
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657984/mapping-the-landscape-of-medical-research-in-the-arab-world-countries-a-comprehensive-bibliometric-analysis
#30
JOURNAL ARTICLE
Shadan Almuhaidib, Rawan Alqahtani, Haifa F Alotaibi, Asma Saeed, Sahar Alnasrallah, Fayez Alshamsi, Saleh A Alqahtani, Waleed Alhazzani
OBJECTIVES: To describe the productivity, performance, and impact of medical research in the Arab world countries. METHODS: We carried out a bibliometric analysis using Clarivate Analytics databases from January 2017 to March 2023. We reported research productivity, national and international research collaboration patterns, impact of Arab medical research output compared to the global average, top medical journals publishing Arab-affiliated research, and performance of the most productive Arab institutions...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657983/one-in-eight-people-are-now-living-with-obesity
#31
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657982/effectiveness-and-safety-of-rivaroxaban-for-anticoagulation-therapy-in-covid-19-a-meta-analysis-of-randomized-controlled-trials
#32
JOURNAL ARTICLE
Xiangbo Shen, Eryue Qiu, Zhao Liu, Xiaopeng Zhu, Yiqian Zeng
OBJECTIVES: To evaluate the effectiveness and safety of rivaroxaban anticoagulation in COVID-19 patients. METHODS: PubMed, Embase, Cochrane Library electronic databases, and ClinicalTrials.gov were searched to identify all relevant randomized controlled trial studies from December 2019 to July 2023. RESULTS: A total of 6 randomized controlled trials, which included a total of 3323 patients, were considered for evaluation. Overall, short-term all-cause mortality and hospitalization rates were not significantly different between the rivaroxaban and control groups...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657981/african-health-ministers-commit-to-end-malaria-deaths
#33
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657980/enteropathy-and-intestinal-malabsorption-in-patients-treated-with-antihypertensive-drugs-a-retrospective-cohort-study
#34
JOURNAL ARTICLE
Sae R Lee, Eun G Lee, Young H Cho, Eun J Park, Young-In Lee, Jung I Choi, Ryuk-Jun Kwon, Soo M Son, Sang Y Lee, Yu H Yi, Gyu L Kim, Yun J Kim, Jeong G Lee, Young Jin Tak, Seung Hun Lee, Young Jin Ra
OBJECTIVES: To investigate differences in the incidence of enteropathy or intestinal malabsorption in patients taking angiotensin II receptor blockers (ARBs), angiotensin-converting enzyme inhibitor (ACEI), calcium channel blocker (CCB), and beta blockers (BBs) at a single center in Korea. METHODS: In this retrospective study, we utilized data from the Yangsan electronic medical records to identify 129,169 patients. These individuals were prescribed olmesartan, other ARBs, ACEI, CCB, and BBs between November 2008 and February 2021...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657979/outcomes-of-carotid-endarterectomy-insights-from-a-single-center-retrospective-cohort-study
#35
JOURNAL ARTICLE
Sultan AlSheikh, Badr Aljabri, Tariq Alanezi, Mussaad Al-Salman, Mohammed Y Aldossary, Abdulatif H Almashat, Hend S Elmutawi, Rakan A Aldoghmani, Talal Altuwaijri, Kaisor Iqbal, Abdulmajeed Altoijry
OBJECTIVES: To analyze the outcomes of carotid endarterectomy in individuals with carotid artery stenosis in the context of a tertiary care center. METHODS: We carried out a retrospective cohort investigation between 2015-2022. Patient data includes demographics, risk factors, preoperative medications, and operative details. The primary outcomes were 30-day postoperative stroke and mortality rates, while the secondary outcome of the study was to assess the morbidity of the procedure...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657978/infected-pulmonary-hydatid-cyst-a-challenging-diagnosis
#36
JOURNAL ARTICLE
Fahad M AlRashed, Dayel A AlShahrani
Echinococcosis is a parasitic infection that is distributed worldwide. Its clinical presentation depends on the size and location of the cyst. A 7-year-old was found with a superimposed infected pulmonary hydatid cyst that was initially misdiagnosed as complicated pneumonia. Our case underscores the challenges of diagnosing and managing echinococcosis, emphasizes the need for a high index of suspicion, and describes the disease's ability to mimic other clinical entities.
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657977/the-prevalence-of-pneumothorax-in-human-immunodeficiency-virus-patients-a-single-center-study
#37
JOURNAL ARTICLE
Mohammed S Ishaq, Esraa Y Arabi
OBJECTIVES: To assess the prevalence, risk factors, and associated complications of pneumothorax that are present in patients with human immunodeficiency virus (HIV) at our institution and to provide an updated local study addressing the association between pneumothorax and HIV. METHODS: This retrospective cohort study examined 161 patients who were admitted with a diagnosis of HIV from June 2017 to May 2022. They were divided into 2 groups depending on the presence of pneumothorax during their stay...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38657976/prognostic-influence-of-weight-loss-on-overweight-obese-young-heart-failure-patients
#38
JOURNAL ARTICLE
Shan He, Xiaonan Guan, Jianjun Zhang
OBJECTIVES: To explore the prognostic influence of weight loss (WL) on young overweight/obesity (OW/OB) individuals with heart failure (HF). METHODS: Heart failure enrollees (younger than 45 years, body mass index [BMI] of ≥25 kg/m2 ) who received medical treatment at Beijing Chaoyang Hospital, Beijing, China, were classified into 2 groups according to whether they experienced significant WL (≥5% from baseline one year after discharge). One-year occurrence rate of major adverse cardiac events (MACEs) comprising cardiac death and rehospitalization for HF was determined...
April 2024: Saudi Medical Journal
https://read.qxmd.com/read/38438218/comparison-of-the-popliteal-artery-and-the-capsule-of-the-posterior-knee-ipack-block-and-the-genicular-nerve-block-in-primary-total-knee-arthroplasty-a-prospective-randomized-trial
#39
JOURNAL ARTICLE
Abdulrahim Dündar, Deniz İpek, Mehmet Yalvaç, Şehmuz Kaya
OBJECTIVES: To compare the efficacy of genicular block and interspace between the popliteal artery and the posterior capsule (IPACK) block in the reduction of postoperative pain, the need for rescue analgesics, and the effects on a range of motion (ROM) in patients with TKA. METHODS: This prospective randomized controlled study was carried out between February and May 2023. Based on the block method, 60 participants were divided into three equal groups. These groups included the IPACK block group (n=20), the genicular block group (n=20), and control group (n=20)...
March 2024: Saudi Medical Journal
https://read.qxmd.com/read/38438217/determining-the-predictors-associated-with-the-difficulty-of-adaptation-to-ageing-of-hospitalized-older-adults-difficulty-of-older-adult-to-aging
#40
JOURNAL ARTICLE
Canan D Barutcu, Hale T Damar
OBJECTIVES: To determine the predictors associated with the difficulty of adaptation to ageing of hospitalized older adults. METHODS: This descriptive cross-sectional study was carried out in a university hospital between October 2019 and March 2020. The sample consisted of 247 older adults. Research data were collected using a Visual Analogue Scale (VAS), the Falls Efficacy Scale (FES) International, Hospital Anxiety and Depression Scale, and Assessment Scale of Adaptation Difficulty for the Elderly (ASADE)...
March 2024: Saudi Medical Journal
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