journal
https://read.qxmd.com/read/37739272/mental-health-among-children-and-adolescents-after-sars-cov-2-infection-a-prospective-study-in-a-tertiary-university-hospital
#1
LETTER
Olivia Mari Matsuo, Livia Lindoso, Heloisa Helena de Sousa Marques, Guilherme V Polanczyk, Sylvia Costa Lima Farhat, Vera Bain, Thais T Fink, Fernanda Martins, Camilla Astley, Priscila Suguita, Vitor Trindade, Simone Correa-Silva, Patricia Palmeira, Camila Sanson Yoshino de Paula, Nadia Litvinov, Juliana Caires O A Ferreira, Neusa Keico Sakita, Bruno Gualano, Clovis Artur A Silva, Maria Fernanda Badue Pereira
No abstract text is available yet for this article.
September 20, 2023: Journal of Infection
https://read.qxmd.com/read/37690670/single-cell-rna-sequencing-reveals-heterogeneity-and-intercellular-crosstalk-in-human-tuberculosis-lung
#2
JOURNAL ARTICLE
Lin Wang, Hui Ma, Zilu Wen, Liangfei Niu, Xinchun Chen, Haiying Liu, Shulin Zhang, Jianqing Xu, Yijun Zhu, Hongwei Li, Hui Chen, Lei Shi, Laiyi Wan, Leilei Li, Meiyi Li, Ka-Wing Wong, Yanzheng Song
Lung inflammation indicated by 18F-labeled fluorodeoxyglucose (FDG) in patients with tuberculosis is associated with disease severity and relapse risk upon treatment completion. We revealed the heterogeneity and intercellular crosstalk in lung tissues with 18F-FDG avidity and adjacent uninvolved tissues from 6 tuberculosis patients by single-cell RNA-sequencing. Tuberculous lungs had an influx of regulatory T cells (Treg), exhausted CD8 T cells, immunosuppressive myeloid cells, conventional DC, plasmacytoid DC, and neutrophils...
September 8, 2023: Journal of Infection
https://read.qxmd.com/read/37690669/molnupiravir-for-intra-household-prevention-of-covid-19-the-move-ahead-randomized-placebo-controlled-trial
#3
JOURNAL ARTICLE
Sady A Alpizar, Jose Accini, Duane C Anderson, Basem Eysa, Isaí Medina-Piñón, Norio Ohmagari, Mykola M Ostrovskyy, Angela Aggrey-Amable, R N Karen Beck, Dana Byrne, Staci Grayson, Peggy M T Hwang, Julia D Lonchar, Julie Strizki, Yayun Xu, Amanda Paschke, Carisa S De Anda, Pamela S Sears
OBJECTIVES: To evaluate efficacy and safety of molnupiravir for intra-household post-exposure prophylaxis (PEP) of COVID-19. METHODS: MOVe-AHEAD was a randomized, controlled, double-blind, phase 3 trial comparing molnupiravir (800mg twice daily for 5 days) with placebo. Eligible participants were adult, unvaccinated, asymptomatic household contacts of patients with laboratory-confirmed COVID-19. The primary efficacy endpoint was the incidence of COVID-19 through day 14 in modified intention-to-treat (MITT) participants (those who received ≥1 dose of study intervention) without detectable SARS-CoV-2 at baseline, termed the MITT-VN population...
September 8, 2023: Journal of Infection
https://read.qxmd.com/read/37689396/distribution-and-risks-of-the-infections-of-humans-and-other-mammals-with-h5-subtype-highly-pathogenic-avian-influenza-viruses-in-2020-2023
#4
LETTER
Ji-Ming Chen, Su-Mei Tan, Rui-Xu Chen, Huan-Yu Gong, Xiu Wang, Shou-Sheng Lu
No abstract text is available yet for this article.
September 7, 2023: Journal of Infection
https://read.qxmd.com/read/37689395/epidemiological-and-strain-characteristics-of-invasive-meningococcal-disease-prior-to-during-and-after-covid-19-pandemic-restrictions-in-england
#5
JOURNAL ARTICLE
Stephen A Clark, Helen Campbell, Sonia Ribeiro, Marta Bertran, Lloyd Walsh, Andrew Walker, Laura Willerton, Aiswarya Lekshmi, Xilian Bai, Jay Lucidarme, Shamez N Ladhani, Ray Borrow
OBJECTIVES: In 2020, COVID-19 pandemic restrictions led to a major suppression of meningococcal disease in England. Here we describe the epidemiology of invasive meningococcal disease (in the three years prior to the COVID-19 pandemic and the three years immediately after the introduction of restrictions. METHODS: The UK Health Security Agency conducts national meningococcal disease surveillance in England consisting of laboratory-based case confirmation with strain characterisation by culture and/or molecular detection, as well as clinical follow-up of all cases...
September 7, 2023: Journal of Infection
https://read.qxmd.com/read/37689394/antibody-correlates-of-protection-against-delta-infection-after-vaccination-a-nested-case-control-within-the-uk-based-siren-study
#6
JOURNAL ARTICLE
Ana Atti, Ferdinando Insalata, Edward J Carr, Ashley D Otter, Sarah Foulkes, Mary Y Wu, Crick Covid Immunity Pipeline, Michelle J Cole, Ezra Linley, Amanda Semper, Tim Brooks, Susan Hopkins, Andre Charlett, Rupert Beale, Victoria Hall
OBJECTIVES: To investigate serological correlates of protection against SARS-CoV-2 B.1.617.2 (Delta) infection after two vaccinations. METHODS: We performed a case-control study, where cases were Delta infections after second vaccine dose and controls were vaccinated, never infected participants, matched by age, gender and region. Sera were tested for anti-SARS-CoV-2 Spike antibody levels (anti-S) and neutralising antibody titres (nAbT), using live virus microneutralisation against Ancestral, Delta and Omicron (BA...
September 7, 2023: Journal of Infection
https://read.qxmd.com/read/37683897/enterococcus-faecalis-endocarditis-risk-assessment-in-patients-with-bacteremia-external-validation-of-the-denova-score
#7
LETTER
Pierre Danneels, Floris Chabrun, Léa Picard, Pauline Martinet, Schéhérazade Rezig, Aurélien Lorleac'h, Rodolphe Buzelé, Aurélie Beaudron, Marie Kempf, Gwenaël Le Moal, Matthieu Revest, David Boutoille, Adrien Lemaignen, Lucia Grandiere-Perez, Mathieu Nacher, Vincent Dubée
No abstract text is available yet for this article.
September 6, 2023: Journal of Infection
https://read.qxmd.com/read/37678625/comment-on-prolonged-vs-short-term-infusion-of-%C3%AE-lactam-antibiotics-for-the-treatment-of-febrile-neutropenia-a-systematic-review-and-meta-analysis
#8
LETTER
Li Zheng, Ming Liu, Xunlin Sun
No abstract text is available yet for this article.
September 5, 2023: Journal of Infection
https://read.qxmd.com/read/37660756/robust-generation-of-neutralising-antibodies-against-omicron-variants-following-bivalent-mrna-booster-vaccine-in-elderly-people-aged-80-years
#9
LETTER
Helen Parry, Rachel Bruton, Grace Uwenedi, Thomas Roberts, Panagiota Sylla, Jonathan Cook, Ahmed Elzaidi, May Lau, Tamsin Drury, Alexander Bray, Soumyajit Mallick, Katie Spencer, Christopher Bentley, Graham McIlroy, Sam Scott, Nicola Logan, Jianmin Zuo, Brian Willett, Paul Moss
No abstract text is available yet for this article.
September 1, 2023: Journal of Infection
https://read.qxmd.com/read/37660755/longitudinal-analysis-of-neutralization-in-sera-from-hcws-receiving-2-doses-of-omicron-ba-4-5-adapted-bivalent-vaccine
#10
LETTER
Masayuki Amano, Yasuko Ichikawa, Shota Matsumoto, Shuzo Matsushita, Shinya Shimada, Hiroaki Mitsuya
No abstract text is available yet for this article.
September 1, 2023: Journal of Infection
https://read.qxmd.com/read/37660754/nasal-mucosal-iga-levels-against-sars-cov-2-and-seasonal-coronaviruses-are-low-in-children-but-boosted-by-reinfection
#11
JOURNAL ARTICLE
Alexander C Dowell, Gokhan Tut, Jusnara Begum, Rachel Bruton, Christopher Bentley, Megan Butler, Grace Uwenedi, Jianmin Zuo, Annabel A Powell, Andrew J Brent, Bernadette Brent, Frances Baawuah, Ifeanyichukwu Okike, Joanne Beckmann, Shazaad Ahmad, Felicity Aiano, Joanna Garstang, Mary E Ramsay, Paul Moss, Shamez N Ladhani
Repeated coronavirus infections in childhood drive progressive maturation of systemic immune responses into adulthood. Analyses of immune responses in children have focused primarily upon systemic assessment but the importance of mucosal immunity is increasingly recognised. We studied virus-specific antibody responses in contemporaneous nasal swab and blood samples from 99 children (4-15 years) and 28 adults (22-56 years), all of whom had prior SARS-CoV-2 infection. Whilst mucosal IgA titres against Influenza and Respiratory Syncytial virus were comparable between children and adults, those against all coronaviruses, including SARS-CoV-2, were lower in children...
September 1, 2023: Journal of Infection
https://read.qxmd.com/read/37657648/differences-caused-by-blood-and-secretion-samples-for-the-detection-of-klebsiella-pneumoniae-using-metagenomic-next-generation-sequencing-a-comparative-analysis
#12
LETTER
Weiming Yao, Shiyan Feng, Liuqing Yang, Yuanlong Lin, Mingxia Zhang, Kanru Cai, Li Xing, Ke Yuan, Hongzhou Lu, Fuxiang Wang
No abstract text is available yet for this article.
August 30, 2023: Journal of Infection
https://read.qxmd.com/read/37652314/sars-cov-2-specific-antibody-and-t-cell-immunity-in-convalescents-after-infection-wave-in-beijing-in-late-2022
#13
JOURNAL ARTICLE
Xuejiao Guan, Qi Huang, Mei Dong, Maozhong Li, Hui Xie, Xiaofeng Wei, Lu Kang, Xue Wang, Aihua Li, Qing Wang, Fang Huang, Quanyi Wang
OBJECTIVES: To evaluate SARS-CoV-2-specific antibody and T-cell responses in convalescents 5 months after infection wave in Beijing from December 2022 to January 2023 to prevent reinfection and severe disease. METHODS: Convalescents and uninfected individuals vaccinated with different doses were enrolled to assess the IFNγ T-cell responses against SARS-CoV-2 prototype strain, BF.7, BQ.1 and XBB. Neutralizing antibodies against prototype strain, BF.7, BA.5 and XBB and immunoglobulin G antibody were further analyzed...
August 29, 2023: Journal of Infection
https://read.qxmd.com/read/37634846/did-the-black-death-give-birth-to-the-healthcare-hero
#14
LETTER
Shay Nair Sharma
No abstract text is available yet for this article.
August 25, 2023: Journal of Infection
https://read.qxmd.com/read/37625552/missing-subunits-of-mpox-replication-complex-possible-impact-on-structural-organization
#15
LETTER
Saathvik R Kannan, Athreya S Reddy, Dana M Burris, Siddappa N Byrareddy, Kamal Singh
No abstract text is available yet for this article.
August 23, 2023: Journal of Infection
https://read.qxmd.com/read/37604211/post-covid-19-condition-a-comprehensive-analysis-of-the-world-health-organisation-definition
#16
LETTER
Laure Carcaillon-Bentata, Tatjana T Makovski, Caroline Alleaume, Valentina Decio, Nathalie Beltzer, Anne Gallay, Sarah Tebeka, Olivier Robineau, Joël Coste
No abstract text is available yet for this article.
August 19, 2023: Journal of Infection
https://read.qxmd.com/read/37604210/evaluation-of-the-contribution-of-shotgun-metagenomics-in-the-microbiological-diagnosis-of-liver-abscesses
#17
JOURNAL ARTICLE
Kimseng Hadrien, Rossi Geoffrey, Danjean Maxime, Jimenez-Araya Bryan, Chaligne Camille, Galy Adrien, Souhail Bérénice, Bert Frédéric, Leflon Véronique, Fihman Vincent, Caillault Amandine, Demontant Vanessa, Seng Sarah, Trawinski Elisabeth, N 'Debi Melissa, Boizeau Laure, Jacquier Hervé, Ronot Maxime, Reizine Edouard, Le Roy Vincent, Lefort Agnès, Rodriguez Christophe, Lepeule Raphaël, Woerther Paul-Louis
BACKGROUND: Shotgun metagenomics (SMg) sequencing has gained a considerable interest, as it enables the detection of any microorganisms through a single analysis. Due to the limitations of standard microbiological approaches, the microbial documentation of liver abscesses (LA), which is crucial for their medical management, can be difficult. Here we aimed to compare the performance of SMg with standard approaches for the microbiological documentation of LA. METHODS: In this retrospective study conducted at two centers, we compared the results of standard microbiology with metagenomics analysis of consecutive LA samples...
August 19, 2023: Journal of Infection
https://read.qxmd.com/read/37579793/covid-19-vaccine-effectiveness-against-hospitalisation-and-death-of-people-in-clinical-risk-groups-during-the-delta-variant-period-english-primary-care-network-cohort-study
#18
JOURNAL ARTICLE
Heather J Whitaker, Ruby Sm Tsang, Rachel Byford, Carole Aspden, Elizabeth Button, Praveen Sebastian Pillai, Gavin Jamie, Debasish Kar, John Williams, Mary Sinnathamby, Gemma Marsden, William H Elson, Meredith Leston, Sneha Anand, Cecilia Okusi, Xuejuan Fan, Ezra Linley, Cathy Rowe, Silvia DArcangelo, Ashley D Otter, Joanna Ellis, Fd Richard Hobbs, Victoria Tzortziou-Brown, Maria Zambon, Mary Ramsay, Kevin E Brown, Gayatri Amirthalingam, Nick J Andrews, Simon de Lusignan, Jamie Lopez Bernal
BACKGROUND: COVID-19 vaccines have been shown to be highly effective against hospitalisation and death following COVID-19 infection. COVID-19 vaccine effectiveness estimates against severe endpoints among individuals with clinical conditions that place them at increased risk of critical disease are limited. METHODS: We used English primary care medical record data from the Oxford-Royal College of General Practitioners Research and Surveillance Centre sentinel network (N>18million)...
August 12, 2023: Journal of Infection
https://read.qxmd.com/read/37567511/determinants-of-influenza-a-infection-rate-in-post-covid-19-era
#19
LETTER
Isabell Wagenhäuser, Juliane Mees, Julia Reusch, Thiên-Trí Lâm, Alexandra Schubert-Unkmeir, Lukas B Krone, Anna Frey, Oliver Kurzai, Stefan Frantz, Lars Dölken, Johannes Liese, Alexander Gabel, Nils Petri, Manuel Krone
No abstract text is available yet for this article.
August 9, 2023: Journal of Infection
https://read.qxmd.com/read/37557958/translating-metagenomics-into-clinical-practice-for-complex-paediatric-neurological-presentations
#20
LETTER
Justin Penner, Jane Hassell, Julianne R Brown, Kshitij Mankad, Nathaniel Storey, Laura Atkinson, Nisha Ranganathan, Alexander Lennon, Jack C D Lee, Dimitrios Champsas, Angelika Kopec, Divya Shah, Cristina Venturini, Garth Dixon, Surjo De, James Hatcher, Kathryn Harris, Kristian Aquilina, Maaike A Kusters, Karyn Moshal, Delane Shingadia, Austen Jj Worth, Giovanna Lucchini, Ashirwad Merve, Thomas S Jacques, Alasdair Bamford, Marios Kaliakatsos, Judith Breuer, Sofia Morfopoulou
No abstract text is available yet for this article.
August 7, 2023: Journal of Infection
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