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Journal of Infection

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https://read.qxmd.com/read/31102602/a-case-of-a-filmarray-me-false-negative-in-meningococcal-meningitisa-case-of-a-filmarray-%C3%A2-me-false-negative-in-meningococcal-meningitis
#1
LETTER
Patricia González-Donapetry, Julio García Rodríguez, Emilio Cendejas Bueno
The FilmArray® meningitis/encephalitis panel detects the 14 most frequent pathogens causing meningitis and/or encephalitis. The cases of FilmArray´s false negative in bacterial meningitis are rarely described in the literature. We are reporting a case of a false negative FilmArray® result for N.meningitidis and how we managed to overcome this situation.
May 15, 2019: Journal of Infection
https://read.qxmd.com/read/31100365/transmission-risk-of-avian-influenza-virus-along-poultry-supply-chains-in-guangdong-china
#2
Jian-Yong Wu, Eric Hy Lau, Jun Yuan, Ming-Ling Lu, Chao-Jun Xie, Kui-Biao Li, Xiao-Wei Ma, Jian-Dong Chen, Yan-Hui Liu, Lan Cao, Mei-Xia Li, Biao Di, Yu-Fei Liu, Jian-Yun Lu, Tie-Gang Li, Xin-Cai Xiao, Da-Hu Wang, Zhi-Cong Yang, Jia-Hai Lu
OBJECTIVES: Avian influenza viruses (AIVs) poise significant risk to human health and the poultry industry. We evaluated the transmission risk along the poultry supply chain. METHODS: During October 2015 and July 2016, four rounds of cross-sectional surveys were performed to characterize AIV spread in farms, transport vehicles, slaughterhouses, wholesale and retail live poultry markets (LPMs). Poultry cloacal and oral swabs, environmental swabs, bioaerosol samples and human sera were collected...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100364/higher-relapse-rate-among-hiv-hcv-coinfected-patients-receiving-sofosbuvir-ledipasvir-for-8-weeks
#3
Anaïs Corma-Gómez, Juan Macías, Dolores Merino MuñOZ, Francisco Téllez, Rafael Granados, Luis E Morano, Ignacio De Los Santos Gil, Francisco J Vera-Méndez, Antonio Collado, Rosario Palacios, Juan A Pineda
OBJECTIVES: To compare the efficacy of sofosbuvir/ledipasvir (SOF/LDV) for 8 weeks (SL8) versus a 12-week course of SOF/LDV (SL12) among HIV/HCV-coinfected patients in clinical practice. In addition we compared sustained virological response (SVR) rates achieved with SL8 in HCV-monoinfected and HIV/HCV-coinfected patients in a real life setting. METHODS: HCV-infected patients were retrospectively selected from the HEPAVIR-DAA and GEHEP-MONO real-life prospective cohorts if they fulfilled the following criteria: 1) Infected with genotype 1; 2) Treatment with SL8 or SL12; 3) Treatment naïve prior to receiving SL8 or SL12; 4) Absence of cirrhosis; 5) Baseline HCV RNA<6 × 106 IU/mL; 6) Reached the scheduled time-point for SVR (SVR12) assessment...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100363/phylogeographic-patterns-of-the-african-swine-fever-virus
#4
LETTER
Xuejuan Shen, Zhiqing Pu, Yiliang Li, Shu Yu, Fucheng Guo, Tingting Luo, Xiaobing Li, Xu Zhang, Wen Luo, Yutan Fan, David M Irwin, Rui-Ai Chen, Yongyi Shen
No abstract text is available yet for this article.
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100362/a-hospital-cluster-combined-with-a-family-cluster-of-avian-influenza-h7n9-infection-in-anhui-province-china
#5
Wenyan Zhang, Kefu Zhao, Jing Jin, Jun He, Wei Zhou, Jinju Wu, Renshu Tang, Wenbo Ma, Caiyu Ding, Wei Liu, Lei Zhang, Rongbao Gao
OBJECTIVES: To identify human-to-human transmission of H7N9 avian influenza virus, we investigated a hospital cluster combined with family cluster in this study. METHODS: We obtained and analyzed clinical, epidemiological and virological data from the three patients. RT-PCR, viral culture and sequencing were conducted for determination of causative pathogen. RESULTS: The index case presented developed pneumonia with fever after exposure to chicken in a poultry farm...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100361/the-incremental-value-of-bronchoalveolar-lavage-for-the-diagnosis-of-pulmonary-tuberculosis-in-a-high-burden-urban-setting
#6
Ping Xu, Peijun Tang, Huafeng Song, Jing Zhao, Hui Chen, Jing Xue, Yunxia Zhai, Yu Pang, Meiying Wu
OBJECTIVES: we prospectively evaluated the use of bronchoalveolar lavage fluid (BALF) specimens to assess their added incremental value to pulmonary tuberculosis (TB) diagnostic strategies used currently in a high-burden urban setting in China. METHODS: A prospective study was conducted of patients with presumptive pulmonary TB registered at the Fifth Hospital of Suzhou between March 2018 and July 2018. BALF samples from patients with initial Xpert-negative sputum results were tested to diagnose TB...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100360/high-diversity-of-invasive-haemophilus-influenzae-isolates-in-france-and-the-emergence-of-resistance-to-third-generation-cephalosporins-by-alteration-of-ftsi-gene
#7
Ala-Eddine Deghmane, Eva Hong, Sara Chehboub, Aude Terrade, Michaël Falguières, Morgan Sort, Odile Harrison, Keith A Jolley, Muhamed-Kheir Taha
BACKGROUND: Invasive infections due to Haemophilus influenzae are infrequent following the implementation of vaccination against H. influenzae of serotype b. However, their changing epidemiology may not be clear due to a lack of appropriate genotyping methods combined with antibiotic susceptibility analyses which do not discriminate invasive and non-invasive isolates. We aimed to describe recent epidemiological trends of invasive H. influenzae infections in France and explore the microbiological characteristics of invasive versus non-invasive isolates...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31100359/torquetenovirus-viremia-for-early-prediction-of-graft-rejection-after-kidney-transplantation
#8
M Solis, A Velay, P Gantner, J Bausson, A Filiputti, R Freitag, B Moulin, S Caillard, S Fafi-Kremer
OBJECTIVES: New biomarkers reflecting the degree of immunosuppression in transplant recipients are needed to provide an optimal personalized balance between rejection and infection risks. METHODS: For this purpose, we investigated TTV viremia dynamics in 66 kidney transplant recipients followed up for two years after transplantation, in relation to BK virus infection and graft rejection. RESULTS: After transplantation, TTV viremia rose by ≥2 log10 copies/mL from baseline to month 3, then declined by ≥1 log10 copies/mL thereafter...
May 14, 2019: Journal of Infection
https://read.qxmd.com/read/31075292/the-codon-usage-bias-of-avian-influenza-a-viruses
#9
LETTER
Wen Luo, Lin Tian, Chuqi Huang, Jiayu Li, Xuejuan Shen, Robert W Murphy, Ming Liao, Yongyi Shen
No abstract text is available yet for this article.
May 7, 2019: Journal of Infection
https://read.qxmd.com/read/31075291/human-herpesvirus-6-infection-after-autologous-stem-cell-transplantation-a-multicenter-prospective-study-in-adult-patients
#10
Marie Balsat, Sylvie Pillet, Emmanuelle Tavernier, Victoria Cacheux, Vanessa Escuret, Cécile Moluçon-Chabrot, Karine Augeul-Meunier, Audrey Mirand, Christel Regagnon, Fabien Tinquaut, Véronique Bousser, Mathieu Oriol, Denis Guyotat, Gilles Salles, Jacques-Olivier Bay, Bruno Pozzetto, Jérôme Cornillon
OBJECTIVES: to prospectively evaluate the incidence and the clinical relevance on hematopoietic reconstitution of HHV-6 infection in autologous hematopoietic stem cell transplantation (ASCT) recipients. METHODS: HHV-6 DNA load was measured in whole blood specimens once during the 7 days before stem cell re-infusion and once a week after transplantation until hematopoietic recovery. Active HHV-6 infection was defined by 2 consecutive positive DNA loads. RESULTS: from July 2012 to February 2015, 196 adult patients undergoing ASCT were enrolled...
May 7, 2019: Journal of Infection
https://read.qxmd.com/read/31051185/a-human-infection-with-a-novel-reassortant-h3n2-swine-virus-in-china
#11
LETTER
Jing Lu, Lina Yi, Yi Jing, Hanqing Tan, Wei Mai, Yingchao Song, Lirong Zou, Lijun Liang, Hong Xiao, Min Kang, Jie Wu, Tie Song, Changwen Ke
No abstract text is available yet for this article.
April 30, 2019: Journal of Infection
https://read.qxmd.com/read/31029695/no-gene-communication-between-the-human-h3n2-and-h1n1-pandemic-2009-influenza-a-viruses
#12
LETTER
Xuejuan Shen, Zhiqing Pu, David M Irwin, Yongyi Shen
No abstract text is available yet for this article.
April 25, 2019: Journal of Infection
https://read.qxmd.com/read/31029694/genetic-characterization-of-h7n4-avian-influenza-virus-in-china-in-2018
#13
LETTER
Bin Xiang, Libin Chen, Jie Song, Peng Xie, Qiuyan Lin, Ming Liao, Chenggang Xu, Tao Ren
No abstract text is available yet for this article.
April 25, 2019: Journal of Infection
https://read.qxmd.com/read/31029693/avian-influenza-a-viruses-h5nx-n1-n2-n6-and-n8-show-different-adaptations-of-their-codon-usage-patterns-to-their-hosts
#14
LETTER
Fucheng Guo, Xuejuan Shen, David M Irwin, Yongyi Shen
No abstract text is available yet for this article.
April 25, 2019: Journal of Infection
https://read.qxmd.com/read/31009653/increased-susceptibility-to-pertussis-in-adults-at-childbearing-age-as-determined-by-comparative-seroprevalence-study-china-2010-2016
#15
Yuxiao Zhang, Zhiyun Chen, Jianhong Zhao, Nan Zhang, Ning Chen, Jing Zhang, Shuming Li, Qiushui He
OBJECTIVES: This study was aimed to determine pertussis specific serum PT-IgG antibodies in healthy individuals during 2010 and 2015/2016 in Beijing, China. METHODS: A total of 3884 healthy individuals were included: 3058 aged 3 to 69 years randomly selected from an epidemiological survey conducted in 2010, and 826 aged 20-39 years selected from those who attended an annual medical examination in 2015/2016. Serum PT-IgG antibodies were determined using the Serion/Virion ELISA kits...
April 19, 2019: Journal of Infection
https://read.qxmd.com/read/30981891/characterization-of-quantiferon-tb-plus-results-in-latent-tuberculosis-infected-patients-with-or-without-immune-mediated-inflammatory-diseases
#16
Teresa Chiacchio, Elisa Petruccioli, Valentina Vanini, Gilda Cuzzi, Umberto Massafra, Gianpiero Baldi, Assunta Navarra, Rossana Scrivo, Claudio Mastroianni, Ilaria Sauzullo, Carmela Esposito, Fabrizio Palmieri, Fabrizio Cantini, Delia Goletti
OBJECTIVES: Screening for latent tuberculosis infection (LTBI) diagnosis is mandatory in patients with immune-mediated inflammatory diseases (IMID) requiring biologics. QuantiFERON-TB-Plus (QFT-P), an LTBI diagnostic test, measures IFN-γ after M. tuberculosis-stimulation in TB1 and TB2 tubes in which a "CD4" or a "CD4 and CD8" response is respectively elicited. Aim of this study is to compare the response to QFT-P of IMID-LTBI patients candidates to a new biological therapy vs LTBI-subjects without IMID...
April 11, 2019: Journal of Infection
https://read.qxmd.com/read/30980839/chronic-relapsing-varicella-zoster-meningitis-successfully-treated-with-varicella-vaccine
#17
LETTER
Johanna Gaiottino, Gavin Giovannoni, Judith Breuer, Julian W Tang
No abstract text is available yet for this article.
April 10, 2019: Journal of Infection
https://read.qxmd.com/read/30978360/incidence-rate-of-depression-as-an-adverse-effect-of-multidrug-resistant-tuberculosis-treatment
#18
LETTER
Yubin Cao, Changhao Yu, Yingyi Wu
No abstract text is available yet for this article.
April 9, 2019: Journal of Infection
https://read.qxmd.com/read/30974130/development-and-internal-validation-of-a-model-for-predicting-60-day-risk-of-invasive-mould-disease-in-patients-with-haematological-malignancies
#19
Marta Stanzani, Nicola Vianelli, Michele Cavo, Dimitrios P Kontoyiannis, Russell E Lewis
OBJECTIVE: Our objective was to develop a model that predicts a patient's risk of developing invasive mould disease (IMD) within 60 days of admission for treatment of a haematological malignancy. METHODS: We analysed 19 risk factors for IMD in a cohort of 1,944 adult patients with haematological malignancies over 4,127 admissions at a haematology referral centre in Northern Italy (2007-2016). We used a multivariable logistic regression to estimate the 60-day probability of developing probable or proven IMD...
April 8, 2019: Journal of Infection
https://read.qxmd.com/read/30974129/septic-shock-among-patients-with-systemic-lupus-erythematosus-short-and-long-term-outcome-analysis-of-a-french-nationwide-database
#20
Arthur Mageau, Karim Sacré, Anne Perozziello, Stéphane Ruckly, Claire Dupuis, Lila Bouadma, Thomas Papo, Jean-François Timsit
OBJECTIVES: We aimed to assess the characteristics, outcomes and costs of septic shock complicating Systemic Lupus Erythematosus (SLE). METHODS: Characteristics of SLE patients experiencing a septic shock in France from 2010 to 2015 were analyzed through the French medico-administrative database. Factors associated with the 1-year post-admission mortality were analyzed, the crude 1-year survival of SLE patients experiencing septic shock was compared to those admitted for another reason, and we compared the 1-year outcome associated with SLE septic shock survival to a matched SLE ICU control population...
April 8, 2019: Journal of Infection
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