Kimseng Hadrien, Rossi Geoffrey, Danjean Maxime, Jimenez-Araya Bryan, Chaligne Camille, Galy Adrien, Souhail Bérénice, Bert Frédéric, Leflon Véronique, Fihman Vincent, Caillault Amandine, Demontant Vanessa, Seng Sarah, Trawinski Elisabeth, N 'Debi Melissa, Boizeau Laure, Jacquier Hervé, Ronot Maxime, Reizine Edouard, Le Roy Vincent, Lefort Agnès, Rodriguez Christophe, Lepeule Raphaël, Woerther Paul-Louis
BACKGROUND: Shotgun metagenomics (SMg) sequencing has gained a considerable interest, as it enables the detection of any microorganisms through a single analysis. Due to the limitations of standard microbiological approaches, the microbial documentation of liver abscesses (LA), which is crucial for their medical management, can be difficult. Here we aimed to compare the performance of SMg with standard approaches for the microbiological documentation of LA. METHODS: In this retrospective study conducted at two centers, we compared the results of standard microbiology with metagenomics analysis of consecutive LA samples...
August 19, 2023: Journal of Infection