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Journal of Affective Disorders

Esther Jiménez, Caterina Del Mar Bonnín, Brisa Solé, Jose Sánchez-Moreno, María Reinares, Carla Torrent, Imma Torres, Estela Salagre, Cristina Varo, Victoria Ruíz, Anna Giménez, Antoni Benabarre, Luís Gutiérrez-Rojas, Jorge Cervilla, Pilar A Sáiz, M Paz García-Portilla, Julio Bobes, Benedikt L Amann, Anabel Martínez-Arán, Eduard Vieta
BACKGROUND: The Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego (TEMPS-A) is a self-administered questionnaire intended to assess five affective temperaments: depressive, cyclothymic, hyperthymic, irritable and anxious. Our objective was to examine the psychometric properties of the TEMPS-A using a sample comprised by patients with bipolar disorder (BD) and healthy controls (HC) and to determine cut-off scores for each temperament. METHODS: Five hundred and ninety-eight individuals (327 BD and 271 HC) completed the TEMPS-A...
February 12, 2019: Journal of Affective Disorders
Li Hongxia, Tang Yuxiao, Shen Zhilei, Sun Yan, Qu Yicui, Shen Jiamin, Xu Xin, Yang Jianxin, Mo Fengfeng, Shen Hui
BACKGROUND: Our previous studies have proved that zinc supplement effectively alleviate depression symptoms in mice, but the mechanisms are still uncertain. Neuroinflammation is considered as an important aspect in pathogenesis of depression. To elucidate the role of zinc on neuroinflammation, in this study, we investigated effects of zinc on lipopolysaccharide (LPS)-induced inflammation in BV2 microglia cells, a kind of innate immune cells in central nervous system. METHODS: BV2 cells were treated by 100 ng/ml LPS to induce inflammatory responses and the effects of zinc sulfate (ZnSO4 ) addition on LPS-induced inflammation were observed...
February 12, 2019: Journal of Affective Disorders
A Svicher, S Romanazzo, F De Cesaris, S Benemei, P Geppetti, F Cosci
BACKGROUND: The Mental Pain Questionnaire (MPQ) is a self-report questionnaire developed to assess mental pain. The aim of the present study was to test the clinimetric properties of the MPQ. METHODS: A sample of 200 migraine outpatients were enrolled; homogeneity of MPQ was assessed by Mokken Analysis; item-level severity and item-level sensitivity were calculated via Two-Parameter Logistic model; Total Information Function was evaluated to assess reliability of MPQ; internal consistency was calculated via Cronbach's alpha and Sijtsma and Molenaar rho; sensitivity and specificity were assessed via Receiver Operating Characteristic curves...
February 11, 2019: Journal of Affective Disorders
Jin-Won Noh, Kyoung-Beom Kim, Yejin Lee, Ju Hyun Lee, Eun Ji Kim, So Hee Lee
BACKGROUND: The purpose of this study was to analyze the mental health status of Danwon students who survived the Sewol ferry disaster. The study also evaluated the mental health effects of the disaster on the survivors. METHODS: Questionnaires were used to collect data from selected respondents. It was found that high family function and adolescent's strengths influence the quality of life of the survivors significantly. RESULTS: Higher scores on the Family Adaptability and Cohesion Evaluation Scales (p < 0...
February 11, 2019: Journal of Affective Disorders
Jasmine Willi, Ulrike Ehlert
BACKGROUND: Within the female life cycle, the perimenopause is considered as a critical period for the development of depression. Prevalence rates are particularly high during this phase. Perimenopausal depression is characterized by affective symptoms as well as menopause-specific somatic complaints. Currently, a variety of questionnaires are used to assess mood during the perimenopause. The aim of this review is to determine the instruments employed to assess perimenopausal depression...
February 11, 2019: Journal of Affective Disorders
Leah Quinlivan, Sarah Steeg, Jamie Elvidge, Rebecca Nowland, Linda Davies, Keith Hawton, David Gunnell, Nav Kapur
BACKGROUND: Risk scales are used widely for assessing individuals presenting to Emergency Departments (EDs) following self-harm. There is growing evidence that risk scales have limited clinical utility in identifying episodes at highest risk of repeat self-harm. However, their cost-effectiveness in terms of treatment allocation and subsequent repeat self-harm is unknown. We aimed to examine the cost-effectiveness of five risk scales (SAD PERSONS Scale, Modified SAD PERSONS Scale, ReACT Self-Harm Rule, Manchester Self-Harm Rule, Barratt Impulsivity Scale) and single item clinician and patient ratings of risk...
February 11, 2019: Journal of Affective Disorders
Arezou Sayad, Mohammad Taheri, Mir Davood Omrani, Hamid Fallah, Vahid Kholghi Oskooei, Soudeh Ghafouri-Fard
BACKGROUND: Long non-coding RNAs (lncRNAs) have established roles in the pathogenesis of diverse human disorders including neuropsychiatric disorders. METHODS: In the current study, we evaluated expression levels of six apoptosis-related lncRNAs (CCAT2, TUG1, PANDA, NEAT1, FAS-AS1 and OIP5-AS1) in the peripheral blood of bipolar disorder (BD) patients and healthy subjects to assess their contribution in the pathogenesis of BD. RESULTS: CCAT2, TUG1 and PANDA were up-regulated in total BD patients compared with total healthy subjects (P values = 0...
February 11, 2019: Journal of Affective Disorders
Mi-Ryung Han, Kyu-Man Han, Aram Kim, Wooyoung Kang, Youbin Kang, June Kang, Eunsoo Won, Woo-Suk Tae, Yunjung Cho, Byung-Joo Ham
BACKGROUND: Bipolar disorder (BD) is one of the most heritable psychiatric disorders. A growing number of whole-exome sequencing (WES) studies for BD has been performed, however, no research has examined the association between single nucleotide variants (SNVs) from WES and structural magnetic resonance imaging (MRI) data. METHODS: We sequenced whole-exomes in 53 patients with BD and 82 healthy control participants at an initial discovery stage and investigated the impacts of SNVs in risk genes from WES analysis on the cortical gray-matter thickness and integrity of white matter tracts and in the following stage...
February 11, 2019: Journal of Affective Disorders
San Lee, Sarah Soyeon Oh, Eun-Cheol Park, Sung-In Jang
BACKGROUND: Overt and subclinical thyroid dysfunction has been reported to be related to depression. Thyroid diseases have been known to occur more frequently in women. However, scarce data are available on effects and sex differences of changes in thyroid-stimulating hormone (TSH) levels, with a normal range of thyroid hormones, on depression. This study aimed to investigate the association between TSH levels and depressive symptoms, according to sex, in individuals from the general population with free thyroxine (fT4) values within the normal range...
February 10, 2019: Journal of Affective Disorders
Antonio Hernández-Martínez, Julian Rodríguez-Almagro, Milagros Molina-Alarcón, Nuria Infante-Torres, Miriam Donate Manzanares, Juan Miguel Martínez-Galiano
BACKGROUND: The relationship between obstetric variables and postpartum post-traumatic stress disorder (PTSD), and its influence on quality of life (QoL), have scarcely been studied. OBJECTIVE: Determine the prevalence of PTSD at postpartum weeks 4 and 6, and its relation with perinatal variables and quality of life METHOD: A cross-sectional study with 2990 Spanish puerperal women in Spain. Data were collected on socio-demographic and obstetric variables, and on newborns...
February 10, 2019: Journal of Affective Disorders
Elisa M T Melloni, Sara Poletti, Benedetta Vai, Irene Bollettini, Cristina Colombo, Francesco Benedetti
BACKGROUND: Cognitive deficits are a core feature of bipolar disorder (BD), and persist during the euthymic phase. White matter (WM) microstructural abnormalities are widely considered a structural marker of BD. Features of illness chronicity, such as illness duration and number of mood episodes, have been associated with worsening of both clinical profile and brain structural alterations. This study examined the role of WM integrity as a possible mediator between illness duration and cognitive performances in a sample of BD patients...
February 8, 2019: Journal of Affective Disorders
Hui Jiang, Lu Niu, Jessica Hahne, Mi Hu, Jing Fang, Minxue Shen, Shuiyuan Xiao
No abstract text is available yet for this article.
February 8, 2019: Journal of Affective Disorders
Flávia Lima, Francisco Diego Rabelo-da Ponte, Joana Bücker, Letícia Czepielewski, Mathias Hasse-Sousa, Raissa Telesca, Brisa Solé, Maria Reinares, Eduard Vieta, Adriane R Rosa
No abstract text is available yet for this article.
February 8, 2019: Journal of Affective Disorders
Nikolina Jovanović, Julian Beezhold, Masaru Tateno, Elizabeth Barrett, Ilias Vlachos, Andrea Fiorillo, Cecile Hanon, Olga Kazakova, Alexander Nawka, Philippe Wuyts, Vanessa Wong, Szilvia Papp, Jasna Rujević, Goran Racetovic, Adriana Mihai, João Gama Marques, Amit Malik, Ulrike Weiss, Teelia Rolko, Marija Rusaka, Nanna Platz Clausen, Elena Shmunk, Anja Podlesek
BACKGROUND: Previous studies have highlighted risks for depression and suicide in medical cohorts, but evidence regarding psychiatric residents is missing. This study aimed to determine rates of depression, suicide ideation and suicide attempt among psychiatric residents and to identify associated individual, educational and work-related risk factors. METHODS: A total of 1980 residents from 22 countries completed the online survey which collected data on depression (PHQ-9), suicidality (SIBQ), socio-demographic profiles, training, and education...
February 7, 2019: Journal of Affective Disorders
Marisa E Marraccini, Leslie A Brick, Lisa L Weyandt, Alyssa Francis, Christine Clarkin, Yumeng Fang
BACKGROUND: College students are at increased risk for self-injurious thoughts and behaviors (SITB) and sexual risk behaviors (SRB). Although students with a history of SITB appear to be more prone to SRB, the mechanisms linking these risk behaviors remain largely unexplored. Previous research points to emotional control (EC), defined as one's awareness and adaptability of emotions, as a potential mechanism explaining the relationship between SITB and SRB.1 METHODS: Data included 722 college students attending two different universities in the northeast and southeast regions of the United States...
February 7, 2019: Journal of Affective Disorders
Wenche Ryberg, Per-Henrik Zahl, Lien My Diep, Nils Inge Landrø, Roar Fosse
BACKGROUND: Suicide prevention is a core task in mental health services. Our objective was to determine whether Collaborative Assessment and Management of Suicidality (CAMS) reduced suicidal thoughts and behaviors and mental health distress more effectively than treatment as usual (TAU) in a heterogeneous patient population within specialized mental health care services. METHODS: In this observer-blinded pragmatic randomized controlled trial participants who scored 13 or above on Beck's Scale for Suicide Ideation-Current (BSSI-C) were included from seven in- and outpatient units...
February 7, 2019: Journal of Affective Disorders
Anja W M M Stevens, Peter J J Goossens, Elise A M Knoppert-van der Klein, Stasja Draisma, Adriaan Honig, Ralph W Kupka
BACKGROUND: Mood disorders can be difficult to treat during pregnancy. There is still lack of evidence whether pregnancy influences their natural course and whether continuation of pharmacotherapy, despite potential risks for the unborn child, is beneficial in preventing recurrence of mood episodes during pregnancy. METHODS: Systematic review conducted according to the PRISMA guidelines, searching Pubmed, PsycINFO, Embase and Cochrane databases up till January 9th, 2018...
February 7, 2019: Journal of Affective Disorders
Joseph M Currier, Joshua D Foster, Charlotte vanOyen Witvliet, Alexis D Abernethy, Lindsey M Root Luna, Sarah A Schnitker, Karl VanHarn, Janet Carter
BACKGROUND: Persons contending with serious mental health difficulties often experience struggles with religious faith and/or spirituality that may also demand clinical attention. However, research has not examined the relative importance of specific forms of spiritual struggles in mental health status or treatment outcomes of psychiatric patients. METHODS: Focusing on 217 adults who completed a spiritually integrated inpatient program, this study examined (1) which struggles in Exline et al...
February 6, 2019: Journal of Affective Disorders
Zhaoqi Jia, Xinyi Li, Xin Yuan, Biao Zhang, Yuan Liu, Jing Zhao, Sen Li
BACKGROUND: The majority of the studies in this area focus on the psychological impact of having diabetic children or adolescents on parents, while a limited number of studies have investigated the effect of diabetes on the mental health status of family members in the general population. Thus, the aim of the current study is to explore the possible association between mental health disorders (depression, anxiety and panic) and diabetes status of family members among a national sample of adults in the United States...
February 6, 2019: Journal of Affective Disorders
Jude Mary Cénat, Kevin Smith, Martine Hébert, Daniel Derivois
BACKGROUND: Most of the scientific literature on cyberbullying and psychosocial consequences associated is based on samples of adolescents. Also, despite their contributions, the few studies with emerging adults were conducted with small or single-site samples. The present study aimed to document the prevalence of cyberbullying among college students in France and the association between cybervictimization, psychological distress and suicidality. METHODS: The sample included 4 626 French undergraduates...
February 6, 2019: Journal of Affective Disorders
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