Armin Attar, Alireza Hosseinpour, Mana Moghadami
Currently, there is controversy regarding the treatment of pregnant patients with mild hypertension (blood pressure 140-159/90-109 mm Hg). While guidelines do not recommend this treatment, results from recent clinical trials are supportive of the treatment. This meta-analysis aimed to clarify if active treatment of mild hypertension during pregnancy results in better maternal and fetal outcomes. All of the potentially eligible randomized controlled trials were retrieved through a systematic database search investigating the impact of pharmacological treatment in mild hypertensive patients on maternal, fetal, and neonatal outcomes...
March 28, 2023: Clinical Cardiology
Nadine Vonderlin, Johannes Siebermair, Amir Mahabadi, Elena Pesch, Miriam Koehler, Dobromir Dobrev, Rolf Alexander Janosi, Tienush Rassaf, Reza Wakili
INTRODUCTION: Identifying the critical isthmus region (CIR) of atrial re-entry tachycardias (AT) is challenging. The Lumipoint® (LP) software, developed for the Rhythmia® mapping system, aims to facilitate the successful ablation of ATs by identifying the CIR. OBJECTIVE: The objective of this study was to evaluate the quality of LP regarding the percentage of arrhythmia-relevant CIR in patients with atypical atrial flutter (AAF). METHODS: In this retrospective study, we analyzed 57 AAF forms...
March 27, 2023: Clinical Cardiology
Xiao-Yu Liu, Jie Zheng, Ku-Lin Li, Shi-Peng Dang, Xiao-Yan Li, Xiao-Xi Zhao, Chao Wang, Zhi-Ming Yu, Ru-Xing Wang
BACKGROUND: This study's intent is to evaluate the usefulness of pattern matching filter (PMF) function combined with robotic magnetic navigation (RMN) in guiding the ablation of premature ventricular contractions (PVCs). HYPOTHESIS: Assume that PMF can improve the outcomes of PVCs ablation using RMN. METHODS: A retrospective analysis was completed consisting of 118 consecutive patients with PVCs who underwent radiofrequency ablation guided by RMN...
March 23, 2023: Clinical Cardiology
Amirmohammad Khalaji, Ali Ajam, Ali Sheikhy, Amir Hossein Behnoush, Aida Fallahzadeh, Jamshid Bagheri, Soheil Mansourian, Shahram Momtahen, Farzad Masoudkabir, Kaveh Hosseini
BACKGROUND: Preoperative hemoglobin (Hb) level is a predictor of in-hospital and midterm mortality in patients undergoing coronary artery bypass grafting surgery (CABG). However, the debate about the different hazards across Hb levels and sex differences in outcome occurrence is still on the table. METHODS: This is a registry-based serial cross-sectional study at Tehran Heart Center. Nonanemic patients who underwent CABG with complete follow-up data were included...
March 23, 2023: Clinical Cardiology
Hicham Skali, David Walker, Jeanette Jiang, Giridharan Gurumoorthy, Kalatu Davies, Tomomi Kimura
BACKGROUND: Despite millions of COVID-19 cases in the United States, it remains unknown whether a history of COVID-19 infection impacts the safety of pharmacologic myocardial perfusion imaging stress testing (pharmacologic MPI). HYPOTHESIS: The aim of this study was to assess if a prior COVID-19 infection was associated with a higher risk of complications during and following pharmacologic MPI testing. METHODS: This retrospective cohort analysis included 179 803 adults (≥18 years) from the PharMetrics® Plus claims database who underwent pharmacologic MPI between March 1, 2020 and February 28, 2021...
March 23, 2023: Clinical Cardiology
Chong Zhang, Shan Zeng, Wenjie Ji, Zhi Li, Haonan Sun, Tianming Teng, Ying Yu, Xin Zhou, Qing Yang
BACKGROUND: Monocytes and fibrinogen (FIB) play important roles in driving acute and reparative inflammatory pathways after myocardial infarction (MI). In humans, there are three subsets of monocytes, namely, CD14++CD16- (Mon1), CD14++CD16+ (Mon2), and CD14+CD16++ (Mon3). During the inflammatory response, monocyte subsets express high levels of integrin αM β2 and protease-activated receptors 1 and 3 to interact with FIB. HYPOTHESIS: However, whether there is a synergistic role of FIB combined with Mon2 counts in prioritizing patients at high risk of future major adverse cardiovascular events (MACEs) after MI remains unknown...
March 22, 2023: Clinical Cardiology
Lars Mizera, Dominik Rath, Jürgen Schreieck, Peter Seizer, Meinrad Paul Gawaz, Martin Duckheim, Christian Eick, Karin A L Müller
BACKGROUND: Risk stratification for transcatheter procedures in patients with severe mitral regurgitation is challenging. Deceleration capacity (DC) has already proven to be a reliable risk predictor in patients undergoing transcatheter aortic valve implantation. We hypothesized, that DC provides prognostic value in patients undergoing transcatheter edge-to-edge mitral valve repair (TEER). METHODS: We retrospectively analyzed electrocardiogram signals from 106 patients undergoing TEER at the University Hospital of Tübingen...
March 22, 2023: Clinical Cardiology
Cheng Yi, Gao Junyi, Liu Fengju, Zhao Qing, Chen Jie
OBJECTIVE: Peripheral arterial disease (PAD) affects a large population and is associated with various adverse clinical outcomes. Lipoprotein(a) has proatherogenic properties and is associated with PAD incidence and severity. The aim of this study is to explore the association between LP(a) and PAD in coronary artery bypass grafting (CABG) patients. METHODS: A total of 1001 patients were included and divided into two groups: low Lp(a) group [LP(a) < 30 mg/dL] and high Lp(a) group [LP(a) ≥ 30 mg/dL]...
March 10, 2023: Clinical Cardiology
Weilun Meng, Xiang Li, Zhongyuan Ren, Yixing Zheng, Jingying Zhang, Haotian Yang, Rong Guo, Hailing Li, Jun Zhang, Yiqian Wang, Peng Jia, Dongdong Zhao, Yawei Xu
BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia and can be treated with catheter ablation (CA) combined with left atrial appendage occlusion (LAAO). The study is designed to compare the safety and efficacy of guiding the combined procedure by digital subtraction angiography (DSA) with or without transesophageal echocardiography (TEE). METHODS: From February 2019 to December 2020, 138 patients with nonvalvular AF who underwent CA combined with LAAO procedure were consecutively included, and two cohorts were built according to intraprocedural guidance (DSA or DSA with TEE)...
March 9, 2023: Clinical Cardiology
Mehak Dhande, Konstantinos N Aronis, Floyd Thoma, Suresh Mulukutla, Aditya Bhonsale, Krishna Kancharla, Alaa Shalaby, Andrew Voigt, N A Mark Estes, Sandeep K Jain, Samir Saba
BACKGROUND: In mild-to-moderate cardiomyopathy, cardiac resynchronization therapy (CRT) is indicated in patients with high burden of right ventricular pacing but not in those with intrinsic ventricular conduction abnormalities. HYPOTHESIS: We hypothesized that CRT positively impacts outcomes of patients with intrinsic ventricular conduction delay and left ventricular ejection fraction (LVEF) of 36%-50%. METHODS: Of 18 003 patients with LVEF ≤ 50%, 5966 (33%) patients had mild-to-moderate cardiomyopathy, of whom 1741 (29%) have a QRS duration ≥120 ms...
March 7, 2023: Clinical Cardiology
Cong Yin, Juan Li, Lin Yuan
No abstract text is available yet for this article.
March 2, 2023: Clinical Cardiology
Shinichi Wada, Yoshitaka Iwanaga, Michikazu Nakai, Yoko M Nakao, Yoshihiro Miyamoto, Teruo Noguchi
BACKGROUND: To examine the utility of fractional flow reserve by coronary computed tomography (CT) angiography (FFRCT ) for predicting major adverse cardiovascular events (MACE) in patients with suspected coronary artery disease (CAD). METHODS: This was a nationwide multicenter prospective cohort study including consecutive 1187 patients aged 50-74 years with suspected CAD and had available coronary CT angiography (CCTA). In patients with ≥50% coronary artery stenosis (CAS), FFRCT was further analyzed...
March 1, 2023: Clinical Cardiology
Mintu P Turakhia, Jennifer D Guo, Allison Keshishian, Rachel Delinger, Xiaoxi Sun, Mauricio Ferri, Cristina Russ, Matthew Cato, Huseyin Yuce, Patrick Hlavacek
BACKGROUND: Atrial fibrillation (AF) prevalence estimates vary and have been based on cohorts with clinically established or diagnosed disease. Undiagnosed AF prevalence estimates are less certain as they are based on nongeneralizable convenience samples. HYPOTHESIS: Because AF is often asymptomatic, it my remain undiagnosed until the development of complications such as stroke or heart failure. Consequently, the observed prevalence of diagnosed AF from the literature may underestimate total disease burden...
March 1, 2023: Clinical Cardiology
Bo Wang, Yue Gao, Yifan Zhao, Chong Xu, Song Zhao, Hailing Li, Yi Zhang, Yawei Xu
BACKGROUND: Coronary microvascular dysfunction is crucial in determining myocardial ischemia; however, the relationship between epicardial coronary diameter stenosis (DS) and the index of microcirculatory resistance (IMR) remains unclear. We sought to explore the distribution of coronary angiography-derived IMR (angio-IMR) in patients with suspected myocardial ischemia. METHODS: The study included 480 patients with suspected myocardial ischemia, all of whom underwent coronary angiography...
March 1, 2023: Clinical Cardiology
Yumin Kim, Andrew D Choi, Anha Telluri, Isabella Lipkin, Andrew J Bradley, Alfateh Sidahmed, Rebecca Jonas, Daniele Andreini, Ravi Bathina, Andrea Baggiano, Rodrigo Cerci, Eui-Young Choi, Jung-Hyun Choi, So-Yeon Choi, Namsik Chung, Jason Cole, Joon-Hyung Doh, Sang-Jin Ha, Ae-Young Her, Cezary Kepka, Jang-Young Kim, Jin Won Kim, Sang-Wook Kim, Woong Kim, Gianluca Pontone, Todd C Villines, Iksung Cho, Ibrahim Danad, Ran Heo, Sang-Eun Lee, Ji Hyun Lee, Hyung-Bok Park, Ji-Min Sung, Tami Crabtree, James P Earls, James K Min, Hyuk-Jae Chang
AIMS: We compared diagnostic performance, costs, and association with major adverse cardiovascular events (MACE) of clinical coronary computed tomography angiography (CCTA) interpretation versus semiautomated approach that use artificial intelligence and machine learning for atherosclerosis imaging-quantitative computed tomography (AI-QCT) for patients being referred for nonemergent invasive coronary angiography (ICA). METHODS: CCTA data from individuals enrolled into the randomized controlled Computed Tomographic Angiography for Selective Cardiac Catheterization trial for an American College of Cardiology (ACC)/American Heart Association (AHA) guideline indication for ICA were analyzed...
February 27, 2023: Clinical Cardiology
Yomna E Dean, Mohamed A Shebl, Samah S Rouzan, Bdoor Ahmed A Bamousa, Nesreen Elsayed Talat, Sana Afreen Ansari, Yousef Tanas, Muaaz Aslam, Sara Gebril, Taher Sbitli, Ramy Eweis, Rameen Shahid, Amr Salem, Heba Ahmed Abdelaziz, Jaffer Shah, Walaa Hasan, Diaa Hakim, Hani Aiash
BACKGROUND: Insomnia has been closely associated with cardiovascular disease (CVD) including myocardial infarction (MI). Our study aims to assess the eligibility of insomnia as a potential risk factor for MI. METHODS: PubMed, Scopus, and Web of Science were searched using terms; such as "Insomnia" and "MI." Only observational controlled studies with data on the incidence of MI among insomniacs were included. Revman software version 5.4 was used for the analysis...
February 25, 2023: Clinical Cardiology
En-Shao Liu, Tse-Hsuan Yang, Ta-Hsin Tai, Cheng-Hung Chiang, Chin-Chang Cheng, Wei-Chun Huang, Guang-Yuan Mar, Feng-Yu Kuo
BACKGROUND: Percutaneous coronary interventions (PCI) in very small vessel lesions represent an intriguing aspect of coronary artery disease (CAD). Uncertainty still exists in stent implantation in very small caliber vessels. This study aimed to evaluate the long-term outcomes of patients treated with 2.0-mm drug-eluting stent (DES). METHOD: This retrospective observational study included 134 patients undergoing PCI with 2.0-mm zotarolimus DES from December 2016 to May 2020...
February 23, 2023: Clinical Cardiology
Wei Zhu, Xingmei Huang, Lili Mei, Liting Zhi, Shili Jiang, Jianling Jin, Cao Zou
BACKGROUND: Identify idiopathic ventricular tachycardia in patients with ventricular premature beats was required to have effectively treatment. HYPOTHESIS: The aim of this study is to investigate the predictive value of Tp-Te interval, Tp-Te/QT ratio, and QRS-T angle of idiopathic ventricular tachycardia in patients with idiopathic ventricular premature beats. METHODS: One hundred and seventy-eight patients who had undergone premature ventricular complex/ventricular tachycardia (PVC/VT) ablation between January 1, 2020 and August 30, 2022 constituted our study population as ventricular arrhythmia group...
February 21, 2023: Clinical Cardiology
Young Jin Youn, Ho Sung Jeon, Young In Kim, Jung-Hee Lee, Young Jun Park, Dong-Hyuk Cho, Jung-Woo Son, Jun-Won Lee, Min-Soo Ahn, Sung Gyun Ahn, Jang-Young Kim, Byung-Su Yoo, Seung-Hwan Lee, Junghan Yoon
BACKGROUND: Diffuse coronary artery disease (CAD) is a prognostic factor after percutaneous coronary intervention (PCI) and requires multiple overlapping stent implantations. HYPOTHESIS: We investigated the impact of ultra-long 48 mm drug-eluting stent (DES) on procedural and clinical outcomes in real-world practice. METHODS: Patients who underwent DES implantation for a lesion length of >40 mm were selected from a prospective registry between 2019 and 2021...
February 20, 2023: Clinical Cardiology
Maurish Fatima, Muhammad Aemaz Ur Rehman, Muhammad W Murad, Huzaifa A Cheema, Sarya Swed
No abstract text is available yet for this article.
February 20, 2023: Clinical Cardiology
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