journal
https://read.qxmd.com/read/37733131/sizzling-fat-curative-endoscopic-resection-of-a-giant-lipoma-causing-colo-colic-intussusception
#1
JOURNAL ARTICLE
Chiara Eberspacher, Stefano Arcieri, Augusto Lauro, Rossella Palma, Enrico Coletta, Francesco Leone Arcieri, Domenico Mascagni, Stefano Pontone
Giant colonic lipomas, tumors that infrequently occur in the gastrointestinal tract, can manifest as bleeding, abdominal pain and, in few cases, obstruction with intussusception. Surgery is usually the treatment of choice. We report the case of a 78 years-old woman with abdominal pain, constipation, and bleeding due to a giant lipoma of the sigmoid colon causing intussusception. After an initial diagnostic colonoscopy, the patient underwent an endoscopic mucosal resection (EMR) without complications. Even if surgery is traditionally the primary therapeutic approach for giant colonic lipomas, selected cases can be successfully treated with EMR...
September 21, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37733130/poor-performance-of-non-invasive-tests-for-advanced-fibrosis-in-nonalcoholic-fatty-liver-disease-a-multicentric-asian-study
#2
JOURNAL ARTICLE
Umang Arora, Ritik M Goyal, Kevin K J Teh, Yiying Pei, George B B Goh, Su Lin, Rahul Kumar, Sagnik Biswas, Manas Vaishnav, Shekhar Swaroop, Piyush Pathak, Sabreena Sheikh, Vishwesh Bharadiya, Anshuman Elhence, Shivanand Gamanagatti, Rajni Yadav, Prasenjit Das, Sandeep Aggarwal, Narendra Choudhary, Prajna Anirvan, Shivaram P Singh, Arka De, Ajay Duseja, Shalimar
BACKGROUND: Non-invasive tests (NITs) are useful to assess advanced fibrosis (AF) in nonalcoholic fatty liver disease (NAFLD). Data from Asian countries suggest that these tests have poor performance. We aimed to assess diagnostic accuracy of established thresholds of biomarker-based NITs and Transient Elastography (TE) in identifying AF and evaluated the utility of a two-step test approach. METHODS: Biopsy-proven 641 NAFLD patients (55.2% males, median age 42 years) were included from three different centers of Asia...
September 21, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37725192/insurance-approval-delay-of-biologic-therapy-dose-escalation-associated-with-disease-activity-in-patients-with-inflammatory-bowel-disease
#3
JOURNAL ARTICLE
Nisha B Shah, Autumn D Zuckerman, Katie R Hosteng, Jessica Fann, Josh DeClercq, Leena Choi, Laura Cherry, David A Schwartz, Sara Horst
BACKGROUND: Dose escalation of self-injectable biologic therapy for inflammatory bowel diseases may be required to counteract loss of response and/or low drug levels. Payors often require completion of a prior authorization (PA), which is a complex approval pathway before providing coverage. If the initial PA request is denied, clinic staff must complete a time and resource-intensive process to obtain medication approval. AIMS: This study measured time from decision to dose escalate to insurance approval and evaluated impact of approval time on disease activity...
September 19, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713039/author-spotlight-joshua-norman
#4
EDITORIAL
Joshua Norman
No abstract text is available yet for this article.
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713038/importance-of-bowel-habits-in-predicting-inadequate-bowel-preparation-a-prospective-observational-study
#5
JOURNAL ARTICLE
Akira Higashimori, Natsumi Maeda, Masami Nakatani, Ikki Yamamoto, Takeshi Yanagida, Daiyu Kin, Yuji Matsumoto, Kenichi Morimoto, Eiji Sasaki, Takashi Fukuda, Tetsuo Arakawa, Yasuhiro Fujiwara
OBJECTIVES: Inadequate bowel preparation (BP) negatively affects the efficacy and quality of colonoscopy. Although constipation has already been reported as one of the most important predictors of inadequate BP, there is limited information on the relation between inadequate BP and bowel habits including constipation-related symptoms, medications, and severity of constipation. METHODS: This single-center, prospective observational study was conducted between August 2019 and May 2020...
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713037/taking-a-long-and-hard-look-at-quality-predictors-of-bowel-preparation-for-colonoscopy
#6
EDITORIAL
Yunho Jung
No abstract text is available yet for this article.
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713036/involvement-in-national-gastroenterological-societies-for-professional-development-and-career-advancement-tips-for-trainees
#7
EDITORIAL
Alana Persaud, Mohammad Bilal
Engaging with national gastroenterological (GI) societies offers a plethora of pathways for professional development at every career stage. While each society has a mission with distinct aims, which provides a different spectrum of opportunities, almost all societies share several common goals. Involvement in national GI organizations can not only help in professional advancement but can be a rewarding and meaningful way to contribute to our field. There are several benefits of engagement with national GI organizations and trainees should see what aligns with their goals to make the best of the opportunities offered by these organizations...
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713035/two-cases-too-little-too-late-surveillance-for-gastric-cancer-in-patients-with-fap
#8
JOURNAL ARTICLE
Marzia Varanese, Ilario Lattina, Flaminia Frattaroli, Daniela Assisi, Lupe Sanchez-Mete, Elena Baldissone, Augusto Lauro, Vittoria Stigliano
Familial adenomatous polyposis is an autosomal dominant disease due to a mutation in the adenomatous polyposis coli (APC) gene. The disease, characterized by the development of adenomas throughout the colon and rectum, is also associated with extracolonic manifestations including gastric fundic polyps and cancer. In this report, we describe two patients with FAP with advanced gastric adenocarcinoma who received systemic chemotherapy. We reviewed the literature published over the past two decades on gastric cancer in FAP patients to assess the clinical course of this disease...
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713034/lifestyle-factors-associated-with-abdominal-pain-in-quiescent-inflammatory-bowel-disease
#9
JOURNAL ARTICLE
Matthew D Coates, Shannon Dalessio, Vonn Walter, August Stuart, Andrew Tinsley, Emmanuelle D Williams, Kofi Clarke
BACKGROUND: Lifestyle factors, including diet, exercise, substance use, and sexual activity, have been shown to influence risk of inflammation and complications in inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Little is known about their potential role in abdominal pain generation in IBD. AIMS: We performed this study to evaluate for relationships between lifestyle factors and abdominal pain in quiescent IBD (QP-IBD)...
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37713033/urban-legend-addressing-knowledge-gaps-in-inflammatory-bowel-disease-epidemiology
#10
EDITORIAL
Courtney L Perry, Christian N Rhudy
No abstract text is available yet for this article.
September 15, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37707748/routine-endoscopy-prior-to-surgical-ostomy-closure-an-obsolete-concept
#11
JOURNAL ARTICLE
Maxine E Schreiber, Marcel A Schneider, Fritz R Murray, Matthias Turina, Christoph Gubler
BACKGROUND: Closure of temporary diverting ostomies is commonly preceded by an endoscopic study of the colonic mucosa and anastomosis, despite lacking evidence of its relevance and impact on subsequent operative management. AIM: We sought to determine the incidence of pathological findings and therefore evaluate the clinical benefit of routine pre-operative endoscopy in asymptomatic patients, hypothesizing sole evaluation of the anastomotic integrity to be sufficient in these cases...
September 14, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37707747/heme-oxygenase-1-modified-bmmscs-activate-ampk-nrf2-fth1-to-reduce-severe-steatotic-liver-ischemia-reperfusion-injury
#12
JOURNAL ARTICLE
Xiaorong Tian, Yuxin Wang, Mengshu Yuan, Weiping Zheng, Huaiwen Zuo, Xinru Zhang, Hongli Song
BACKGROUND: Ischemia-reperfusion injury (IRI) is an important cause of graft dysfunction post-liver transplantation, where donor liver with severe steatosis is more sensitive to IRI. Liver IRI involves ferroptosis and can be alleviated by heme oxygenase-1-modified bone marrow mesenchymal stem cells (HO-1/BMMSCs). AIMS: To explore the role and mechanism of HO-1/BMMSCs in severe steatotic liver IRI. METHODS: A severe steatotic liver IRI rat model and a hypoxia/reoxygenation (H/R) of severe steatosis hepatocyte model were established...
September 14, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37695549/irritable-bowel-syndrome-like-symptoms-in-quiescent-inflammatory-bowel-disease-a-practical-approach-to-diagnosis-and-treatment-of-organic-causes
#13
REVIEW
Jane Lim, Ali Rezaie
BACKGROUND: Despite achieving remission in inflammatory bowel disease (IBD), persistent gastrointestinal symptoms are common in quiescent IBD. While irritable bowel syndrome (IBS) is commonly diagnosed in IBD, IBS-like symptoms of recurrent abdominal pain and altered bowel habits can also be attributed to a wide range of overlapping gastrointestinal (GI) etiologies and systemic disorders with GI manifestations that often do not respond to conventional IBS therapies. Delay in diagnosis of these conditions can lead to ongoing patient suffering, reduced quality of life, repetition of invasive testing, increased healthcare utilization, and potentially unnecessary empirical escalation of IBD-related treatments...
September 11, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37684433/mboat7-rs641738-variant-is-not-associated-with-an-increased-risk-of-hepatocellular-carcinoma-in-a-latin-american-cohort
#14
JOURNAL ARTICLE
Spencer Goble, Joseph Akambase, Jhon Prieto, Domingo Balderramo, Javier Diaz Ferrer, Angelo Z Mattos, Marco Arrese, Enrique Carrera, Zwier M A Groothuismink, Jeffrey Oliveira, Andre Boonstra, Jose D Debes
BACKGROUND: The rs641738 C > T single-nucleotide polymorphism of MBOAT7 has been associated with hepatocellular carcinoma (HCC) and nonalcoholic fatty liver disease (NAFLD). Latin Americans have high rates of HCC and NAFLD, but no assessment between MBOAT7 and HCC has been performed in this population. AIMS: We provide the first assessment of the impact of MBOAT7 on HCC risk in Latin Americans. METHODS: Patients were prospectively recruited into the ESCALON network, designed to collect samples from Latin American patients with HCC in 6 South American countries (Argentina, Ecuador, Brazil, Chile, Peru, and Colombia)...
September 8, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37682374/low-incidence-of-colorectal-advanced-neoplasia-during-surveillance-in-individuals-with-a-family-history-of-colorectal-cancer
#15
JOURNAL ARTICLE
Meghan I Barnett, Molla M Wassie, Charles Cock, Peter A Bampton, Erin L Symonds
BACKGROUND: Family history of colorectal cancer (CRC) is used to stratify individuals into risk categories which determine timing of initial screening and ongoing CRC surveillance. Evidence for long-term CRC risk following a normal index colonoscopy in family history populations is limited. AIMS: To assess the incidence of advanced neoplasia and associated risk factors in a population undergoing surveillance colonoscopies due to family history of CRC. METHODS: Surveillance colonoscopy findings were examined in 425 individuals with a family history of CRC, a normal index colonoscopy and a minimum of 10 years of follow-up colonoscopies...
September 8, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37679574/anlotinib-attenuates-liver-fibrosis-by-regulating-the-transforming-growth-factor-%C3%AE-1-smad3-signaling-pathway
#16
JOURNAL ARTICLE
Ye-Ting Wu, Qi-Zhe Li, Xue-Ke Zhao, Mao Mu, Gao-Liang Zou, Wei-Feng Zhao
BACKGROUND: Hepatic stellate cell hyperactivation is a central link in liver fibrosis development, transforming growth factor β1 (TGF-β1) is a key activator of HSCs. AIMS: This study investigated whether anlotinib attenuates CCl4 induced liver fibrosis in mice and explored its antifibrotic mechanism. METHODS: We used the human hepatic stellate cell line LX-2 for in vitro assays and used TGF-β1 to induce hepatic fibrosis in LX-2 cells...
September 8, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37676630/mitochondrial-dna-copy-number-a-damage-associated-molecular-pattern-molecule-can-predict-pancreatic-necrosis-and-is-correlated-with-the-severity-of-acute-pancreatitis
#17
JOURNAL ARTICLE
Ghada M Ezzat, Soha M Nageb, Mostafa Abd-Allah Haredi, Muhammad Abbas El-Masry
BACKGROUND: Mitochondrial DNA (mtDNA) is a damage-associated molecular pattern molecule that can trigger an immune-inflammatory response during pancreatic necrosis (PN). AIM: To evaluate the role of mtDNA in the detection of PN and severe acute pancreatitis (SAP). METHODS: The present study included 40 AP patients and 30 controls. AP patients were grouped into mild AP (MAP, n = 15), moderately severe AP (MSAP, n = 17), and SAP (n = 8)...
September 7, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37676629/spontaneous-hyperinflation-of-gastric-weight-loss-balloon
#18
JOURNAL ARTICLE
Karthik Mathialagan, David Parsons, Thiruvengadam Muniraj
No abstract text is available yet for this article.
September 7, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37672151/natural-course-of-common-bile-duct-microlithiasis
#19
JOURNAL ARTICLE
Yufang Cui, Jianglong Hong, Chen Shi, Cui Hu, Xiaochang Liu, Zhangwei Xu, Junjun Bao, Yang Li, Qiao Mei
BACKGROUND: Common bile duct microlithiasis (CBDM) with a diameter of ≤ 3 mm can pass spontaneously without causing any symptoms, but in some cases, it can also cause severe cholangitis and pancreatitis. The optimal strategy for managing CBDM is yet to be determined. METHODS: Data of 154 patients with CBDM were collected and divided into two groups: with endoscopic retrograde cholangiopancreatography (with ERCP, n = 82) and without ERCP (n = 72)...
September 6, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37665427/first-clostridioides-difficile-recurrence-is-highest-following-concomitant-antimicrobial-administration-during-and-within-30-days-of-treatment
#20
JOURNAL ARTICLE
Abdelkader Chaar, John Damianos, Rabia Rizwan, Houssam Al-Nahhas, Muhammad Sohail Mansoor, Prabin Sharma, Umer Malik, Paul Feuerstadt
BACKGROUND: Clostridioides difficile infection (CDI) is an epidemic with the strongest risk factor being antibiotic usage. Patients who get CDI frequently require concomitant antibiotics for other indications around the time of their infection. AIMS: To assess the recurrence of CDI (rCDI) in patients receiving concomitant antibiotics at the same time or shortly thereafter treatment of CDI. METHODS: We retrospectively reviewed records for patients with their first inpatient CDI episode...
September 4, 2023: Digestive Diseases and Sciences
journal
journal
27586
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.