Umang Arora, Ritik M Goyal, Kevin K J Teh, Yiying Pei, George B B Goh, Su Lin, Rahul Kumar, Sagnik Biswas, Manas Vaishnav, Shekhar Swaroop, Piyush Pathak, Sabreena Sheikh, Vishwesh Bharadiya, Anshuman Elhence, Shivanand Gamanagatti, Rajni Yadav, Prasenjit Das, Sandeep Aggarwal, Narendra Choudhary, Prajna Anirvan, Shivaram P Singh, Arka De, Ajay Duseja, Shalimar
BACKGROUND: Non-invasive tests (NITs) are useful to assess advanced fibrosis (AF) in nonalcoholic fatty liver disease (NAFLD). Data from Asian countries suggest that these tests have poor performance. We aimed to assess diagnostic accuracy of established thresholds of biomarker-based NITs and Transient Elastography (TE) in identifying AF and evaluated the utility of a two-step test approach. METHODS: Biopsy-proven 641 NAFLD patients (55.2% males, median age 42 years) were included from three different centers of Asia...
September 21, 2023: Digestive Diseases and Sciences