Shruti Bhattacharya, Shankar Prasad Nagaraju, Ravindra Attur Prabhu, Dharshan Rangaswamy, Indu Ramachandra Rao, Mohan V Bhojaraja, Srinivas Vinayak Shenoy
UNLABELLED: Percutaneous renal biopsy, although essential for renal disease diagnosis, is associated with a number of post-biopsy complications ranging from gross haematuria to AV fistula to death. In this study, we carried out an active haematoma surveillance and attempted to correlate renal sonological parameters-kidney length, renal parenchymal changes, renal cortical and parenchymal thickness for their potential use in prediction of post-renal biopsy complications. METHODS: This was a prospective study done from April 2022 to April 2023 on all adult patients undergoing native or transplant kidney biopsy...
July 12, 2024: Irish Journal of Medical Science
Tom R Doyle, Martin S Davey, James P Toale, Conor O'Driscoll, Colin G Murphy
No abstract text is available yet for this article.
July 11, 2024: Irish Journal of Medical Science
Doha El-Sayed Ellakwa, Khaleda Sayed Amr, Moushira Erfan Zaki, Miral Refeat, Hala Mohamed Banksle
BACKGROUND: Zinc finger protein 1 (ZPR1), encoded by the ZNF259 gene, plays crucial roles in transcriptional regulation and cell cycle progression. Despite its known functions, its specific involvement in Metabolic Syndrome (MetS) remains debated. Genome-wide association studies have identified several genes, including ZNF259, implicated in lipid metabolism and associated with MetS. Single nucleotide polymorphisms (SNPs) in ZNF259 have been linked to altered lipid metabolism during the development of MetS...
July 10, 2024: Irish Journal of Medical Science
Benjamin M Mac Curtain, Wanyang Qian, Aaron O'Mahony, Avinash Deshwal, Reuben D Mac Curtain, Hugo C Temperley, Niall O Sullivan, Zi Qin Ng
BACKGROUND: Textbook outcome (TO) is a composite measure used in surgery to evaluate post operative outcomes. No review has synthesised the evidence in relation to TO regarding the elements surgeons are utilising to inform their TO composite measure and the rates of TO achieved. METHODS: Our systematic review and meta analysis was conducted in line with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) recommendations. PubMed, EMBASE, and Cochrane central registry of controlled trials were searched up to 8th November 2023...
July 10, 2024: Irish Journal of Medical Science
Anmar B Al-Dewachi, Sura O Al-Dewachi
BACKGROUND: Diabetes mellitus is a major health problem with a variety of implications: cellular, metabolic, and hematological. Hematological alterations observed in type 2 diabetes are related to hyperglycemia and have a vital role in vascular-associated diabetes complications which could be used as a marker for these complications. The aim of this study is to assess the association between hematological indices and blood glucose levels in patients with type 2 diabetes attending outpatient clinics in Mosul...
July 9, 2024: Irish Journal of Medical Science
Ahmed Lutfi, Deirdre Hayes-Ryan, Elmarie Cottrell, Richard A Greene
BACKGROUND: Methotrexate (MTX) is used in clinical practice as a medical treatment option in patients with early pregnancy complications like ectopic pregnancy. AIMS: To review systemic MTX therapy use in the first trimester of pregnancy in our hospital and to examine subsequent clinical outcomes. METHODS: Retrospective review of all women treated with systemic MTX in early pregnancy identified from electronic prescription records from 1 January 2018 to 31 December 2020 at Cork University Maternity Hospital, Ireland...
July 9, 2024: Irish Journal of Medical Science
Edward Moore
No abstract text is available yet for this article.
July 6, 2024: Irish Journal of Medical Science
Ye Li, Jiang Xue, Zhaohua Zhang, Wei Wang, Yulong Wang, Weiquan Zhang
BACKGROUND: The compositional and structural changes of gut microbiota were closely related to the status of Henoch-Schönlein purpura (HSP). AIMS: To investigate if clinical indicators and gut microbiota differ between HSP patients with or without gastrointestinal (GI) involvement and to explore the alterations of fecal microbiota in HSP children with and without GI symptoms. METHODS: A total of 22 children with HSP were enrolled in the study...
July 5, 2024: Irish Journal of Medical Science
Muhammed Tekinhatun, İbrahim Akbudak, Mehmet Özbek, Mehmet Turmak
INTRODUCTION: Coronary artery disease (CAD) is a leading cause of death worldwide. Accurate diagnosis and management are critical. Non-invasive imaging, such as coronary computed tomography angiography (CCTA), is vital for early diagnosis and treatment planning. This study evaluates the accuracy of CAD-Reporting and Data System (CAD-RADS) scoring and the compatibility between CCTA and invasive coronary angiography (ICA) in patients suspected of having CAD. MATERIALS AND METHODS: From January 1, 2022 to January 15, 2024, 214 patients suspected of CAD underwent both CCTA and ICA...
July 4, 2024: Irish Journal of Medical Science
Adel Mouffokes, Youssef Soliman, Basma Ehab Amer, Tungki Pratama Umar, Ahmed Reda Gonnah, Mohamed Hatem Ellabban, Basel Abdelazeem
Patients with diabetes mellitus (DM) are at higher risk of cardiovascular events, particularly acute myocardial infarction (MI). Sodium-glucose cotransporter 2 inhibitors (SGLT2i) can improve cardiac outcomes among heart failure individuals, however, the effects on acute myocardial infarction remain unclear. This meta-analysis investigates the impact of empagliflozin in diabetic patients following acute myocardial infarction. We comprehensively searched PubMed, Scopus, Cochrane, and Web of Science through August 10th, 2023...
July 3, 2024: Irish Journal of Medical Science
Yani Fan, Sujie Wang, Yue Lv, Guoyan Shi, Yadan Lu, Lili Chen
OBJECTIVE: To validate the predictive performance of the THRIVE, ASTRAL, and iScore scales for clinical functional outcomes following mechanical thrombectomy (MT) for acute ischemic stroke (AIS). METHODS: A total of 111 patients meeting the inclusion criteria were included in this study, with 59 (53.2%) having a good prognosis and 52 (46.8%) having a poor prognosis. MedCalc software was applied to plot receiver operating characteristic (ROC) curves, calculate the area under the curve (AUC), and compare the predictive efficacy of the three scales two by two using Delong text...
July 2, 2024: Irish Journal of Medical Science
Lana Al Doori, Peter G Zaki, Vivek Joshi
INTRODUCTION: Originally designed to evaluate the application of foundational scientific knowledge in clinical contexts, the United States Medical License Exam (USMLE) Step 1 evolved into a comparative tool for assessing candidates with similar educational foundations. This transition heightened the pressure on medical students to excel in the exam. In response, collaborative efforts involving the National Board of Medical Examiners prompted a change from reporting scores to a pass/fail system...
July 2, 2024: Irish Journal of Medical Science
Lyndon Yerng Hsien Low, Kevin Clesham, Susan E Murphy, Ruari MacNiocaill, Marcus Timlin, May Cleary
INTRODUCTION: In Irish orthopaedic centres without dedicated spinal services, the care of patients is facilitated through tertiary referral centres in Dublin, Cork & Galway. The outpatient waiting list for elective spinal opinion remains lengthy and challenging. Previous practice in University Hospital Waterford (UHW) necessitated an assessment with a local non-spinal orthopaedic specialist following a GP referral, incurring up to a 2-year wait prior to subspecialist spinal referral...
June 28, 2024: Irish Journal of Medical Science
K F Daly, B M Mac Curtain, E Collins, M Lincoln, E MacCraith, G Lennon, B B McGuire
BACKGROUND: Ureteric colic is a common emergency urological presentation [1]. When operative intervention is required, retrograde ureteroscopy is the most common approach. There are multiple treatment strategies including primary ureteroscopy (URS), staged ureteroscopy, and deferred ureteroscopy following ureteric stent placement. The approach is based on a number of clinical and stone factors. This study assesses the factors which predict stone clearance at the initial procedure. AIMS: All patients diagnosed with an obstructing ureteric stone who were managed operatively in a consecutive 12-month period were included...
June 28, 2024: Irish Journal of Medical Science
Kadriye Ebru Akar, Pelin Bagci
BACKGROUND/AIMS: Necrosis is an important pathological feature that reflects high malignancy potential in tumors such as hepatocellular carcinoma and renal cell carcinoma. We aimed to elucidate the prognostic impact of necrosis in ampullary carcinomas. MATERIALS AND METHODS: We reviewed 101 consecutive cases of ampullary carcinoma for tumor necrosis, types of necrosis, macroscopic and microscopic histopathological subtypes, lymphatic-vascular-perineural invasions, and other histopathological parameters...
June 26, 2024: Irish Journal of Medical Science
Sevda Uzun
OBJECTIVE: This systematic review and meta-analysis aimed to assess the effectiveness of nurses' psychosocial interventions for addressing sensory deprivation in intensive care units (ICUs). MATERIALS AND METHODS: A comprehensive search of PubMed, Web of Science, EBSCOhost, Google Scholar, CİNAHL, Embase, Cochrane Library, and YÖK Thesis Center databases was conducted from August 2023 to May 2024, without any temporal restrictions. In addition, a physical search was made in the university library for grey literature...
June 25, 2024: Irish Journal of Medical Science
Kathryn McKnight, Oluwadamilola Omotosho, Samher Jassim, Amanda Cotter
BACKGROUND: Endometriosis is the leading cause of chronic pelvic pain in women of reproductive age with debilitating effects on quality of life, yet no cure exists. Exercise yields the potential in providing women with a non-invasive, non-pharmacological method of symptom control. AIM(S): Present up-to-date knowledge regarding how exercise may contribute to the management of endometriosis-related symptoms. OBJECTIVE(S): Discuss: 1. The pathophysiology surrounding exercise and endometriosis...
June 25, 2024: Irish Journal of Medical Science
Yani Fan, Yue Lv, Meng Fu, Jianhua Wang, Ying Cui, Binbin Zhang, Yadan Lu, Lili Chen
OBJECTIVE: In this study, the relationship between maximum carotid plaque area and stroke prognosis was analysed by carotid ultrasonography, and the relevant risk factors affecting the prognosis of acute ischaemic stroke (AIS) were investigated to provide novel insights into stroke prevention and management. METHODS: A total of 205 AIS patients with carotid plaques were included in this study. Based on the mRS score at discharge, patients with AIS were classified into the good prognosis group (mRS ≤ 2) and poor prognosis group (mRS ≥ 3)...
June 18, 2024: Irish Journal of Medical Science
Huseyin Ulger, Ferhat Icme, Cenk Parlatan, Begum Seyda Avci, Erdem Aksay, Akkan Avci
BACKGROUND: Intracranial hemorrhages is one of the major causes of mortality and morbidity worldwide, and there is still no effective biomarker to predict prognosis. AIM: We aimed to determine the effectiveness of high sensitive troponin I (hs-cTn-I) levels to predict the prognosis of spontaneous intracerebral hemorrhage (sICH) by comparing Glasgow Coma Score (GCS) and hematoma volume with hs-cTn-I levels. METHODS: This study was planned as a retrospective observational study...
June 18, 2024: Irish Journal of Medical Science
Yani Fan, Feifei Chen, Shuangmei Yan, Sujie Wang, Sai Zhang, Xiaohong He, Lili Chen
OBJECTIVE: A few clinical studies have been conducted on the prognostic value of the Essen score in acute cerebral infarction (ACI), and this study explores whether the Essen score can assess the prognosis of ACI. METHODS: Data were collected from 1176 patients with ACI. The patients were divided into three groups on the basis of the Essen score, with groups 1, 2 and 3 having scores of 0-2, 3-6 and 7-9, respectively. Logistic multivariate analysis was performed to analyse the predictors of poor prognosis in patients with ACI...
June 15, 2024: Irish Journal of Medical Science
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