Asif Ahmad Bhat, Yassine Riadi, Muhammad Afzal, Pooja Bansal, Harpreet Kaur, Mahamedha Deorari, Haider Ali, Moyad Shahwan, Waleed Hassan Almalki, Imran Kazmi, Sami I Alzarea, Hairsh Dureja, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains a serious problem in the world of healthcare. In recent years, the role of ncRNA has emerged as a pivotal aspect in the intricate landscape of cellular regulation. The exploration of ncRNA-mediated regulatory networks reveals their profound influence on key molecular pathways orchestrating pyroptotic responses during septic conditions. Through a comprehensive analysis of current literature, we navigate the diverse classes of ncRNAs, including miRNAs, lncRNAs, and circRNAs, elucidating their roles as both facilitators and inhibitors in the modulation of pyroptotic processes...
February 23, 2024: Pathology, Research and Practice