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Journals Neuroscience and Biobehavioral...

Neuroscience and Biobehavioral Reviews

https://read.qxmd.com/read/37236385/emerging-concepts-towards-a-translational-framework-in-alzheimer-s-disease
#1
REVIEW
Danielle Cozachenco, Eduardo R Zimmer, Mychael V Lourenco
Over the past decades, significant efforts have been made to understand the precise mechanisms underlying the pathogenesis of Alzheimer's disease (AD), the most common cause of dementia. However, clinical trials targeting AD pathological hallmarks have consistently failed. Refinement of AD conceptualization, modeling, and assessment is key to developing successful therapies. Here, we review critical findings and discuss emerging ideas to integrate molecular mechanisms and clinical approaches in AD. We further propose a refined workflow for animal studies incorporating multimodal biomarkers used in clinical studies - delineating critical paths for drug discovery and translation...
May 24, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37236384/the-influence-of-physical-activity-on-neural-responses-to-visual-food-cues-in-humans-a-systematic-review-of-functional-magnetic-resonance-imaging-studies
#2
REVIEW
Abdulrahman M Dera, Tonghui Shen, Alice E Thackray, Elanor C Hinton, James A King, Lewis James, Paul S Morgan, Nathan Rush, Masashi Miyashita, Rachel L Batterham, David J Stensel
This systematic review examined whether neural responses to visual food-cues measured by functional magnetic resonance imaging (fMRI) are influenced by physical activity. Seven databases were searched up to February 2023 for human studies evaluating visual food-cue reactivity using fMRI alongside an assessment of habitual physical activity or structured exercise exposure. Eight studies (1 exercise training, 4 acute crossover, 3 cross-sectional) were included in a qualitative synthesis. Structured acute and chronic exercise appear to lower food-cue reactivity in several brain regions, including the insula, hippocampus, orbitofrontal cortex (OFC), postcentral gyrus and putamen, particularly when viewing high-energy-density food cues...
May 24, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37230235/ultra-high-field-imaging-of-the-amygdala-a-narrative-review
#3
REVIEW
Cedric Fabian Kirstein, Onur Güntürkün, Sebastian Ocklenburg
The amygdala is an evolutionarily conserved core structure in emotion processing and one of the key regions of interest in affective neuroscience. Results of neuroimaging studies focusing on the amygdala are, however, often heterogeneous since it is composed of functionally and neuroanatomically distinct subnuclei. Fortunately, ultra-high-field imaging offers several advances for amygdala research, most importantly more accurate representation of functional and structural properties of subnuclei and their connectivity...
May 23, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37225064/stress-and-traumatic-brain-injury-an-inherent-bi-directional-relationship-with-temporal-and-synergistic-complexities
#4
REVIEW
Justin Brand, Stuart J McDonald, Jodie R Gawryluk, Brian R Christie, Sandy R Shultz
Traumatic brain injury (TBI) and stress are prevalent worldwide and can both result in life-altering health problems. While stress often occurs in the absence of TBI, TBI inherently involves some element of stress. Furthermore, because there is pathophysiological overlap between stress and TBI, it is likely that stress influences TBI outcomes. However, there are temporal complexities in this relationship (e.g., when the stress occurs) that have been understudied despite their potential importance. This paper begins by introducing TBI and stress and highlighting some of their possible synergistic mechanisms including inflammation, excitotoxicity, oxidative stress, hypothalamic-pituitary-adrenal axis dysregulation, and autonomic nervous system dysfunction...
May 22, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37225063/re-wilding-model-organisms-opportunities-to-test-causal-mechanisms-in-social-determinants-of-health-and-aging
#5
REVIEW
Matthew N Zipple, Caleb C Vogt, Michael J Sheehan
Social experiences are strongly associated with individuals' health, aging, and survival in many mammalian taxa, including humans. Despite their role as models of many other physiological and developmental bases of health and aging, biomedical model organisms (particularly lab mice) remain an underutilized tool in resolving outstanding questions regarding social determinants of health and aging, including causality, context-dependence, reversibility, and effective interventions. This status is largely due to the constraints of standard laboratory conditions on animals' social lives...
May 22, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37225062/advancing-social-behavioral-neuroscience-by-integrating-ethology-and-comparative-psychology-methods-through-machine-learning
#6
REVIEW
Joeri Bordes, Lucas Miranda, Bertram Müller-Myhsok, Mathias V Schmidt
Social behavior is naturally occurring in vertebrate species, which holds a strong evolutionary component and is crucial for the normal development and survival of individuals throughout life. Behavioral neuroscience has seen different influential methods for social behavioral phenotyping. The ethological research approach has extensively investigated social behavior in natural habitats, while the comparative psychology approach was developed utilizing standardized and univariate social behavioral tests. The development of advanced and precise tracking tools, together with post-tracking analysis packages, has recently enabled a novel behavioral phenotyping method, that includes the strengths of both approaches...
May 22, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37225061/designing-a-neuroclinical-assessment-of-empathy-deficits-in-psychopathy-based-on-the-zipper-model-of-empathy
#7
REVIEW
Man Him Ho, Benjamin Thomas Kemp, Hedwig Eisenbarth, Ronald J P Rijnders
Ho, M.H., Kemp, B.T., Eisenbarth, H. & Rijnders, R.J.P. Designing a neuroclinical assessment of empathy deficits in psychopathy based on the Zipper Model of Empathy. NEUROSCI BIOBEHAV REV YY(Y) XXX-XXX, 2023. The heterogeneity of the literature on empathy highlights its multidimensional and dynamic nature and affects unclear descriptions of empathy in the context of psychopathology. The Zipper Model of Empathy integrates current theories of empathy and proposes that empathy maturity is dependent on whether contextual and personal factors push affective and cognitive processes together or apart...
May 22, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37216998/coping-styles-vary-with-species-sociality-and-life-history-a-systematic-review-and-meta-regression-analysis
#8
REVIEW
Renée A Duckworth, Kathryn C Chenard, Lexis Meza, Maria Carolina Beiriz
Despite a long history of animal studies investigating coping styles, the causal connections between behavior and stress physiology remain unclear. Consistency across taxa in effect sizes would support the idea of a direct causal link maintained by either functional or developmental dependencies. Alternatively, lack of consistency would suggest coping styles are evolutionarily labile. Here, we investigated correlations between personality traits and baseline and stress-induced glucocorticoid levels using a systematic review and meta-analysis...
May 20, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37211151/the-promise-of-great-apes-as-model-organisms-for-understanding-the-downstream-consequences-of-early-life-experiences
#9
REVIEW
Stacy Rosenbaum, Christopher W Kuzawa
Early life experiences have a significant influence on adult health and aging processes in humans. Despite widespread interest in the evolutionary roots of this phenomenon, very little research on this topic has been conducted in humans' closest living relatives, the great apes. The longitudinal data sets that are now available on wild and captive great ape populations hold great promise to clarify the nature, evolutionary function, and mechanisms underlying these connections in species which share key human life history characteristics...
May 19, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37209932/the-nature-and-neurobiology-of-fear-and-anxiety-state-of-the-science-and-opportunities-for-accelerating-discovery
#10
REVIEW
Shannon E Grogans, Eliza Bliss-Moreau, Kristin A Buss, Lee Anna Clark, Andrew S Fox, Dacher Keltner, Alan S Cowen, Jeansok J Kim, Philip A Kragel, Colin MacLeod, Dean Mobbs, Kristin Naragon-Gainey, Miquel A Fullana, Alexander J Shackman
Fear and anxiety play a central role in mammalian life, and there is considerable interest in clarifying their nature, identifying their biological underpinnings, and determining their consequences for health and disease. Here we provide a roundtable discussion on the nature and biological bases of fear- and anxiety-related states, traits, and disorders. The discussants include scientists familiar with a wide variety of populations and a broad spectrum of techniques. The goal of the roundtable was to take stock of the state of the science and provide a roadmap to the next generation of fear and anxiety research...
May 18, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37207842/neurophysiological-and-psychosocial-mechanisms-of-fibromyalgia-a-comprehensive-review-and-call-for-an-integrative-model
#11
REVIEW
Ana Margarida Pinto, Mariana Luís, Rinie Geenen, Filipe Palavra, Mark A Lumley, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Winfried Häuser, Eva Kosek, Marina López-Solà, Philip Mease, Tiago Reis Marques, Johannes W G Jacobs, Paula Castilho, José A P da Silva
Research into the neurobiological and psychosocial mechanisms involved in fibromyalgia has progressed remarkably in recent years. Despite this, current accounts of fibromyalgia fail to capture the complex, dynamic, and mutual crosstalk between neurophysiological and psychosocial domains. We conducted a comprehensive review of the existing literature in order to: a) synthesize current knowledge on fibromyalgia; b) explore and highlight multi-level links and pathways between different systems; and c) build bridges connecting disparate perspectives...
May 17, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37201591/the-integration-of-action-oriented-multisensory-information-from-target-and-limb-within-the-movement-planning-and-execution
#12
REVIEW
Ivan Camponogara
The planning and execution of a grasping or reaching movement toward targets we sense with the other hand requires integrating multiple sources of sensory information about the limb performing the movement and the target of the action. In the last two decades, several sensory and motor control theories have thoroughly described how this multisensory-motor integration process occurs. However, even though these theories were very influential in their respective field, they lack a clear, unified vision of how target-related and movement-related multisensory information integrates within the action planning and execution phases...
May 16, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37196926/objective-models-of-subjective-feelings
#13
JOURNAL ARTICLE
Stefano Palminteri, Romane Cecchi
No abstract text is available yet for this article.
May 15, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37196925/parents-physiological-reactivity-to-child-distress-and-associations-with-parenting-behaviour-a-systematic-review
#14
REVIEW
Shaylea D Badovinac, Cheryl Chow, Miranda G Di Lorenzo-Klas, Heather Edgell, David B Flora, Rebecca R Pillai Riddell
This systematic review and narrative synthesis characterized parents' physiological stress responses to child distress and how parents' physiological and behavioural responses relate. The review was pre-registered with PROSPERO (#CRD42021252852). In total, 3,607 unique records were identified through Medline, Embase, PsycINFO, and CINAHL. Fifty-five studies reported on parents' physiological stress responses during their young child's (0-3 years) distress and were included in the review. Results were synthesized based on the biological outcome and distress context used and risk of bias was evaluated...
May 15, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37196924/30-years-of-american-society-for-neural-therapy-and-repair-asntr-a-personal-perspective-at-the-intersection-of-science-politics-and-culture
#15
REVIEW
Paul R Sanberg, Donna Morrison, Kimberly B Bjugstad
The American Society for Neural Therapy and Repair (ASNTR) started 30 years ago in 1993 as the American Society for Neural Transplantation (ASNT), with an emphasis on neural transplantation. Through the years, the Society has been shaped as much by our expanding knowledge of neurodegenerative disorders and how to treat them as it has by politics and culture. What once felt like a leash on neuroscience research, has turned into an advantage as neural transplantation evolved into neural therapy and repair. This brief commentary provides a personalized account of our research during the Society's years...
May 15, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37196923/what-are-c-tactile-afferents-and-how-do-they-relate-to-affective-touch
#16
REVIEW
Annett Schirmer, Ilona Croy, Rochelle Ackerley
Since their initial discovery in cats, low-threshold C-fiber mechanoreceptors have become a central interest of scientists studying the affective aspects of touch. Their pursuit in humans, here termed C-tactile (CT) afferents, has led to the establishment of a research field referred to as "affective touch", which is differentiated from "discriminative touch". Presently, we review these developments based on an automated semantic analysis of more than 1000 published abstracts as well as empirical evidence and the solicited opinions of leading experts in the field...
May 15, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37182799/a-review-of-interspecific-social-play-among-nonhuman-animals
#17
REVIEW
Heather J B Brooks, Gordon M Burghardt
BROOKS, H.J.B. & G.M. Burghardt. A comparative review of interspecific social play among nonhuman animals. NEUROSCI BIOBEHAV REV XX(X) XXX-XXX, XXXX.- Few species play socially with another species, hereafter called interspecific social play (ISP). ISP involves reading and responding appropriately to social cues of other species, often taxonomically remote, and has implications for perception, communication, and cognition. We reviewed information on non-human ISP from both print media and videos from YouTube and Reddit...
May 12, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37178944/comparison-of-oncogenes-tumor-suppressors-and-micrornas-between-schizophrenia-and-glioma-the-balance-of-power
#18
REVIEW
James S Brown
The risk of cancer in schizophrenia has been controversial. Confounders of the issue are cigarette smoking in schizophrenia, and antiproliferative effects of antipsychotic medications. The author has previously suggested comparison of a specific cancer like glioma to schizophrenia might help determine a more accurate relationship between cancer and schizophrenia. To accomplish this goal, the author performed three comparisons of data; the first a comparison of conventional tumor suppressors and oncogenes between schizophrenia and cancer including glioma...
May 11, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37178943/a-map-of-spatial-navigation-for-neuroscience
#19
REVIEW
Eloy Parra-Barrero, Sandhiya Vijayabaskaran, Eddie Seabrook, Laurenz Wiskott, Sen Cheng
Spatial navigation has received much attention from neuroscientists, leading to the identification of key brain areas and the discovery of numerous spatially selective cells. Despite this progress, our understanding of how the pieces fit together to drive behavior is generally lacking. We argue that this is partly caused by insufficient communication between behavioral and neuroscientific researchers. This has led the latter to under-appreciate the relevance and complexity of spatial behavior, and to focus too narrowly on characterizing neural representations of space-disconnected from the computations these representations are meant to enable...
May 11, 2023: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/37172924/multiple-chemical-sensitivity-it-s-time-to-catch-up-to-the-science
#20
REVIEW
John Molot, Margaret Sears, Hymie Anisman
Multiple chemical sensitivity (MCS) is a complex medical condition associated with low dose chemical exposures. MCS is characterized by diverse features and common comorbidities, including fibromyalgia, cough hypersensitivity, asthma, and migraine, and stress/anxiety, with which the syndrome shares numerous neurobiological processes and altered functioning within diverse brain regions. Predictive factors linked to MCS comprise genetic influences, gene-environment interactions, oxidative stress, systemic inflammation, cell dysfunction, and psychosocial influences...
May 10, 2023: Neuroscience and Biobehavioral Reviews
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