Linde van Lee, Sarah R Crozier, Izzuddin M Aris, Mya T Tint, Suresh Anand Sadananthan, Navin Michael, Phaik Ling Quah, Sian M Robinson, Hazel M Inskip, Nicholas C Harvey, Mary Barker, Cyrus Cooper, Sendhil S Velan, Yung Seng Lee, Marielle V Fortier, Fabian Yap, Peter D Gluckman, Kok Hian Tan, Lynette P Shek, Yap-Seng Chong, Keith M Godfrey, Mary F F Chong
Background: Choline status has been positively associated with weight and fat mass in animal and human studies. As evidence examining maternal circulating choline concentrations and offspring body composition in human infants/children is lacking, we investigated this in two cohorts. Methods: Maternal choline concentrations were measured in the UK Southampton Women's Survey (SWS; serum, n = 985, 11 weeks' gestation) and Singapore Growing Up Towards healthy Outcomes (GUSTO); n = 955, 26-28 weeks' gestation) mother-offspring cohorts...
January 11, 2019: International Journal of Epidemiology