Journals International Journal of Artif...

International Journal of Artificial Organs
Wun Fung Hui, Wing Lum Cheung, Kam Lun Hon, Shu Wing Ku
Extracorporeal blood purification (EBP) is increasingly applied for bilirubin removal in critical care setting. We retrospectively reviewed the clinical features of children aged 1 month to 18 years old who received EBP for hyperbilirubinemia and explored the bilirubin removal kinetics by hemoadsorption (HA) in the pediatric intensive care unit of Hong Kong Children's Hospital from 3/2019 to 7/2022. Among the 14 episodes of EBP from six patients with a median age (interquartile range [IQR]) of 9...
March 24, 2023: International Journal of Artificial Organs
Marko Kutleša, Marija Santini, Vladimir Krajinović, Neven Papić, Branimir Gjurašin, Juraj Krznarić, Viktor Kotarski
At the beginning of the COVID-19 pandemic, the role of extracorporeal membrane oxygenation (ECMO) was uncertain and the outcomes of ECMO-treated patients were unfavorable. During the pandemic, medical community realized that carefully selected patients may benefit from ECMO support. The goal of the study was to present the outcomes of ECMO-treated patients with severe COVID-19 ARDS referred to the respiratory ECMO hub in Croatia and to determine variables that influenced the outcome. Our study included all adult patients with confirmed COVID-19 ARDS that required ECMO treatment, in the period between February 2020 and April 2022...
March 24, 2023: International Journal of Artificial Organs
Anna Garasz, Juliusz Huber, Magdalena Grajek, Przemysław Daroszewski
OBJECTIVE: The study aimed to describe properties and to prove diagnostic usefulness of motor evoked potentials (MEPs) recordings from muscles versus nerves of lower extremities when induced at lumbar levels with magnetic field. METHODS: Methodologically similar MEPs recordings from muscles and nerves of lower extremities were performed once in healthy volunteers ( N  = 43) and patients with disc-root conflicts at lumbar spine levels ( N  = 43, proven in MRI studies)...
March 24, 2023: International Journal of Artificial Organs
Suijiao Wei, Jing Jiao, Yan Yu, Xiujuan Tian, Xiaoxia Yang, Shidong Feng, Yajuan Li, Peng Zhang, Ming Bai
BACKGROUND: Maintenance hemodialysis (MHD) patients are often admitted to the hospital for severe morbidities. Prolonged intermittent renal replacement therapy (PIRRT) is required during the hospital staying. There are controversial opinions on the use of arteriovenous fistula (AVF) as vascular access for PIRRT in MHD patients. METHODS: Patients with AVF who accepted PIRRT in our center between January 2014 and June 2021 were retrospectively screened. AVF dysfunction and patient mortality were assessed as endpoints...
March 21, 2023: International Journal of Artificial Organs
Shulei Li, Donghai Jin, Xingmin Gui, Guangmao Liu, Xihang Jiang
BACKGROUND: Cardiac functions and support modes of left ventricular assist device (LVAD) will influence the pump inner flow field and blood damage potential. METHODS: Computational fluid dynamics (CFD) method and lumped-parameter-model (LPM) were applied to investigate the impacts of cardiac functions under full (9000 rpm) and partial (8000 rpm) support modes in an axial pump. RESULTS: The constitution of hemolysis index (<mml:math xmlns:mml="http://www...
March 20, 2023: International Journal of Artificial Organs
Miquel Gomez, Marta Arias-Guillén, Francisco Maduell
The hemoconcentration effect for middle weight solutes in hemodialysis is corrected by oversimplified methods based on hematocrit changes or distribution volume variations. Here we implemented a variable volume dual pool kinetic model targeted at obtaining a precise correction factor equation for extracellularly distributed solutes based on relevant kinetic parameters such as the ultrafiltration to dry weight ratio UF/DW, the dialyzer clearance, Kd , the intercompartment mass-transfer coefficient, Kc , and the central compartment to extracellular volume ratio, α...
March 18, 2023: International Journal of Artificial Organs
Changjun Mu, Akihiro C Yamashita
Continuous renal replacement therapy (CRRT) has become the most commonly used acute blood purification therapy for critically ill patients. As a key point of extracorporeal blood circulation, the CRRT filter plays a decisive role in therapeutic efficacy. However, few in vitro studies have been conducted on CRRT filters, particularly concerning the effects of design factors on filter effectiveness and safety profile; no comprehensive evaluation system has been established. Here, we designed nine CRRT filters with various combinations of hollow fiber packing density ( PD ) and housing shape (effective hollow fiber length ( L ) and inner housing diameter ( D ) ratio ( L / D ratio)) and introduced a high-frequency sampling pressure monitor to accurately monitor small changes in transmembrane pressure ( TMP ) and ultrafiltration rate ( UFR ) over time...
March 12, 2023: International Journal of Artificial Organs
Mahwash Kassi, Tanushree Agrawal, Jiaqiong Xu, Hernan Gerardo Marcos-Abdala, Raquel Araujo-Gutierrez, Thomas Macgillivray, Erik E Suarez, Rayan Yousefzai, Nadia Fida, Ju H Kim, Imad Hussain, Ashrith Guha, Barry Trachtenberg, Arvind Bhimaraj, Su Min Chang, Jerry Estep
We sought to evaluate whether differences in left ventricular assist device (LVAD) canula alignment are associated with stroke. There is a paucity of clinical data on contribution of LVAD canulae alignment to strokes. We conducted a retrospective analysis of patients who underwent LVAD implantation at Houston Methodist hospital from 2011 to 2016 and included those who had undergone cardiac computed tomography (CT) with contrast. LVAD graft alignment using X-ray, echocardiography, and cardiac CT was evaluated...
March 9, 2023: International Journal of Artificial Organs
Thummaporn Naorungroj, Ian Baldwin, Glenn Eastwood, Rinaldo Bellomo
BACKGROUNDS: In patients with liver failure, continuous renal replacement therapy (CRRT) without anticoagulation may be necessary. A new heparin coated membrane (oXiris® ) may prolong circuit life in this setting. OBJECTIVES: In liver failure patients not receiving anticoagulation, to compare CRRT circuit life with the oXiris® versus the AN69 ST100 (usual care) membrane. METHODS: Randomized single cross-over trial. RESULTS: We studied 20 patients and 39 circuits...
March 9, 2023: International Journal of Artificial Organs
Zittermann Armin, Pilz Stefan, Morshuis Michiel, Gummert Jan F, Milting Hendrik
Driveline infection is a frequent complication in recipients of durable left ventricular assist devices (LVAD), but its cause is largely unclear. Since vitamin D supplementation can reduce the risk of infections, we aimed at investigating the association of vitamin D deficiency with driveline infection. In 154 patients with continuous flow LVAD implants, we assessed 2-year risk of driveline infection according to vitamin D status (circulating 25-hydroxyvitamin D < 25 nmol/L or ⩾25 nmol/L). Of the study cohort, 34% ( n  = 53) had 25-hydroxyvitamin D concentrations <25 nmol/L...
March 9, 2023: International Journal of Artificial Organs
Yoshihiro Tange, Reo Sunakawa, Shigenori Yoshitake
BACKGROUNDS: Nitric oxide has a broad-spectrum antibacterial property promising as a new therapeutic agent for severe acute respiratory syndrome coronavirus-2 because nitric oxide donor (such as S-nitroso-N-acetylpenicillamine) reduces the replication of coronavirus-2. Patients with coronavirus disease 2019 undergoing dialysis generally have a higher mortality rate than the general population. Although the higher mortality rate in these patients may be related to their advanced age, it has been suggested that plasma nitrite and nitrate levels (products of nitric oxide metabolism) are significantly decreased after hemodialysis which may compromise the nitrate-nitrite-nitric oxide pathway and impair nitric oxide homeostasis...
February 24, 2023: International Journal of Artificial Organs
Marc O Maybauer, Dirk M Maybauer, Massimo Capoccia
A systematic review of the role of extracorporeal life support (ECLS) in pediatric patients with burn and smoke inhalation injury was undertaken. A systematic search of the literature according to a specific combination of keywords to ascertain the effectiveness of this treatment strategy was conducted. A total of 14 articles out of 266 were considered suitable for the analysis in pediatric patients. The PICOS approach and PRISMA flow chart were followed for the purpose of this review. Despite the limited number of studies on the subject, ECMO in burn and smoke inhalation injury provides an additional level of support in pediatric patients leading to positive outcomes...
February 18, 2023: International Journal of Artificial Organs
Tarek M Tantway, Amr A Arafat, Monirah A Albabtain, Makhlouf Belghith, Ahmed A Osman, Mohamed A Aboughanima, Muhammad T Abdullatif, Youssef A Elshoura, Mohammed M AlBarak
BACKGROUND: Sepsis could affect the outcomes of patients with postcardiotomy cardiogenic shock supported with extracorporeal membrane oxygenation (ECMO). Our objectives were to characterize sepsis patients with ECMO support for postcardiotomy cardiogenic shock and assess its predictors and effect on patients' outcomes. METHODS: This retrospective study included 103 patients with ECMO for postcardiotomy cardiogenic shock from 2009 to 2020. Patients were divided according to the occurrence and timing of sepsis into three groups...
February 6, 2023: International Journal of Artificial Organs
Melanie Hau, Ka-Man Fong, Shek-Yin Au
No abstract text is available yet for this article.
February 1, 2023: International Journal of Artificial Organs
Alberto Marabotti, Pietro Bertini, Gianluca Paternoster, Giovanni Landoni, Fabio Guarracino
No abstract text is available yet for this article.
February 1, 2023: International Journal of Artificial Organs
Mustafa Kocacikli
A person becomes disabled when they lose any of their sensory organs, the eye being one of the most delicate. Loss of an eye can happen due to different reasons and can be restored using different materials and strategies. Ocular defects and congenital deformations show up as a result of tumors or injury. For the most part, fabricated eyes are accessible as ocular prostheses. This method describes how to create a custom ocular prosthesis using a digital photo and UV printing. The greatest esthetically pleasing results are also achieved using this production method, which does not necessitate painting or color-selecting expertise...
January 27, 2023: International Journal of Artificial Organs
Amnuay Kleebayoon, Viroj Wiwanitkit
No abstract text is available yet for this article.
January 16, 2023: International Journal of Artificial Organs
Lanfang Li, Qiuxiao Ma, Junyu Mou, Min Wang, Jingxue Ye, Guibo Sun
PURPOSE: This study aimed to observe the effect of basic fibroblast growth factor (bFGF) gel preparation on wound repair in a full-thickness skin defect rat model and to further explore its mechanism. METHODS: The full-thickness skin defect model of Wistar rats was created with circular wounds of 20 mm or 10 mm in diameter on both sides of the spine. The animals were divided into the normal, model, control gel, and bFGF gel groups (300 IU/cm2 )...
January 10, 2023: International Journal of Artificial Organs
Yi Wang, Chenjie Zhou, Yu Fu, Linya Zhang, Shusong Liu, Lei Cai, Zesheng Jiang, Xiaoping Xu, Lei Feng, Yi Gao
BACKGROUND: Acute liver failure (ALF) is a severe liver disease with high morbidity and mortality rates. Animal models are important for research on ALF. This study aimed to establish a reproducible, Tibetan miniature pig model of D-galactosamine-induced ALF and verify it using a dual plasma molecular adsorption system (DPMAS). METHODS: Tibet miniature pigs were randomly divided into four groups (A, B, C, D) after catheterization. D-galactosamine (D-gal) at 0.45, 0...
January 4, 2023: International Journal of Artificial Organs
Raziye Yazıcı, Mehdi Yeksan
BACKGROUND: To prolong survival and to provide a better quality of life (QoL) are two aims at the forefront in the care of peritoneal dialysis (PD) patients. In this study we aimed to determine frequency of sexual dysfunction (SD) and influencing factors in PD patients. METHODS: Of the 201 patients, 114 under 65 years and on chronic ambulatory PD for at least 3 months were enrolled. Forty-nine females and 65 males completed the study. Survey forms were applied using face-to-face interview method...
December 30, 2022: International Journal of Artificial Organs
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