Mohammed Amine Ikhanjal, Mohammed Ali Elourid, Chaimae Zouine, Houda El Alami, Khaoula Errafii, Hassan Ghazal, Najib Alidrissi, Fadil Bakkali, Adnane Benmoussa, Salsabil Hamdi
BACKGROUND AND AIMS: There is tremendous increase in type 2 diabetes mellitus (T2DM) worldwide. The impact of FTO gene polymorphisms on the risk of T2DM is not yet clear because of the controversial results of studies. This meta-analysis aimed to better clarify the association between three FTO gene polymorphisms SNPs (rs9939609, rs8050136 and rs17817449) and T2DM in a larger combined population worldwide. MATERIAL AND METHODS: A comprehensive search on the PubMed, Science Direct, and Web of Science databases was conducted to identify investigations in relationship between different FTO gene polymorphisms (rs9939609, rs8050136 and rs17817449) and T2DM globally...
September 9, 2023: Gene