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Current Problems in Cardiology

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https://read.qxmd.com/read/30665662/heart-failure-postdischarge-clinic-a-pharmacist-led-approach-to-reduce-readmissions
#1
REVIEW
Rasha Al-Bawardy, Angela Cheng-Lai, Lendita Prlesi, Manaf Assafin, Shuo Xu, Kiana Chen, Samvit Tandan, Chino S Aneke, Sandhya Murthy, Ileana L Piña
No abstract text is available yet for this article.
January 5, 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30704792/aging-micrornas-and-heart-failure
#2
REVIEW
Maria Cristina Florio, Alessandra Magenta, Sara Beji, Edward G Lakatta, Maurizio C Capogrossi
Aging is a major risk factor for heart failure, one of the leading causes of death in Western society. The mechanisms that underlie the different forms of heart failure have been elucidated only in part and the role of noncoding RNAs is still poorly characterized. Specifically, microRNAs (miRNAs), a class of small noncoding RNAs that can modulate gene expression at the posttranscriptional level in all cells, including myocardial and vascular cells, have been shown to play a role in heart failure with reduced ejection fraction...
December 29, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30573160/the-medical-and-endovascular-treatment-of-pad-a-review-of-the-guidelines-and-pivotal-clinical-trials
#3
REVIEW
Rajan A G Patel, Rahul Sakhuja, Christopher J White
Peripheral arterial disease (PAD) is a global health problem. The risk factors for developing PAD have been clearly described in the literature, as have the medical therapies and preventative strategies for the prevention and treatment of PAD. Unfortunately, PAD patients remain undertreated with regard to guideline-directed medical therapy. During the last 2 decades, endovascular therapies for PAD have evolved such that randomized controlled trial level data are available for the treatment of lower extremity PAD at every major anatomic segment...
November 30, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30686402/foreword
#4
(no author information available yet)
No abstract text is available yet for this article.
April 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30623775/foreword
#5
(no author information available yet)
No abstract text is available yet for this article.
March 2019: Current Problems in Cardiology
https://read.qxmd.com/read/29784533/long-qt-syndrome-a-comprehensive-review-of-the-literature-and-current-evidence
#6
REVIEW
Syed Raza Shah, Ki Park, Richard Alweis
Long QT syndrome (LQT) represents a heterogeneous family of cardiac electrophysiologic disorders characterized by QT prolongation and T-wave abnormalities on the electrocardiogram. It is commonly associated with syncope, however, sudden cardiac death can occur due to torsades de pointes. LQT is a clinical diagnosis and should be suspected in individuals on the basis of clinical presentation, family history and ECG characteristics. Management is focused on the prevention of syncope and ultimately sudden death...
March 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30580765/foreword
#7
(no author information available yet)
No abstract text is available yet for this article.
February 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30172549/tetralogy-of-fallot-case-based-update-for-the-treatment-of-adult-congenital-patients
#8
Joseph A R Englert, Tripti Gupta, Abdulaziz Uthman Joury, Sangeeta B Shah
No abstract text is available yet for this article.
February 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30454822/foreword
#9
(no author information available yet)
No abstract text is available yet for this article.
January 2019: Current Problems in Cardiology
https://read.qxmd.com/read/29731112/degenerative-mitral-stenosis-from-pathophysiology-to-challenging-interventional-treatment
#10
REVIEW
Marko Banovic, Mark DaCosta
Mitral stenosis (MS) is characterized by obstruction of left ventricular inflow as a result of narrowing of the mitral valve orifice. Although its prevalence has declined over the last decade, especially in developed countries, it remains an important cause of morbidity and mortality.  The most often cause of MS worldwide is still postrheumatic mitral valve disease. However, in developed countries, degenerative or calcific changes cause MS in a siginificant proportion of patients. Although the range of treatment for mitral valve disease has grown over the years in parallel with transcatheter therapies for aortic valve disease, these improvements in mitral valve disease therapy have experienced slower development...
January 2019: Current Problems in Cardiology
https://read.qxmd.com/read/30724164/foreword
#11
(no author information available yet)
No abstract text is available yet for this article.
December 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30545650/increasing-diversity-in-clinical-trials-overcoming-critical-barriers
#12
REVIEW
Luther T Clark, Laurence Watkins, Ileana L Piña, Mary Elmer, Ola Akinboboye, Millicent Gorham, Brenda Jamerson, Cassandra McCullough, Christine Pierre, Adam B Polis, Gary Puckrein, Jeanne M Regnante
Clinical trial results provide the critical evidence base for evaluating the safety and efficacy of new medicines and medical products. Efficacy and safety may differ among population subgroups depending on intrinsic/extrinsic factors, including sex, age, race, ethnicity, lifestyle, and genetic background. Racial and ethnic minorities continue to be underrepresented in cardiovascular and other clinical trials. Although barriers to diversity in trials are well recognized, sustainable solutions for overcoming them have proved elusive...
November 9, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30301511/foreword
#13
(no author information available yet)
No abstract text is available yet for this article.
November 2018: Current Problems in Cardiology
https://read.qxmd.com/read/29576333/enhancing-participation-in-cardiac-rehabilitation-a-question-of-proximity-and-integration-of-outpatient-services
#14
REVIEW
Cemal Ozemek, Shane A Phillips, Bo Fernall, Mark A Williams, Thomas D Stamos, Samantha Bond, Hannah Claeys, Deepika R Laddu, Ross Arena
Numerous investigations have established the strong clinical utility of cardiac rehabilitation, while clinical guidelines continually call for a high level of referral and participation. Historically, medical facilities have faced challenges referring eligible patients to cardiac rehabilitation, enrolling only a small portion of those receiving referral. Consequently, less than ~10% of qualifying patients receive any amount of cardiac rehabilitation. This sobering figure has prompted many efforts to identify barriers to referral as well as enrollment and accordingly propose strategies to bolster participation rates...
November 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30497690/significance-of-pulmonary-hypertension-in-hypertrophic-cardiomyopathy
#15
REVIEW
Anupam Mitra, Raktim Kumar Ghosh, Dhrubajyoti Bandyopadhyay, Gopal Chandra Ghosh, Ankur Kalra, Carl Lavie
Hypertrophic cardiomyopathy (HCM) is the most prevalent hereditary cardiac disease characterized by the presence of left ventricular and/or septal hypertrophy in the absence of other underlying cardiac disorders. Patients of HCM have a broad range of clinical presentation from being asymptomatic to severely ill condition requires hospitalization and urgent management. Broadly, HCM is classified in two variants: obstructive and nonobstructive. The mainstay of diagnosis is through echocardiography. As HCM chiefly affect the left heart, pulmonary hypertension (PH) is an expected complication of this disease...
October 17, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30217253/foreword
#16
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Current Problems in Cardiology
https://read.qxmd.com/read/29397197/accurate-prediction-of-false-st-segment-elevation-myocardial-infarction-ready-for-prime-time
#17
Mark R Heckle, Nephertiti Efeovbokhan, Fridjof Thomas, Mary Blumer, Mason Chumpia, Uzoma Ibebuogu, Guy L Reed, Rami N Khouzam
The incidence of inappropriate cardiac catheterization lab activation for treatment of a false ST-segment elevation myocardial infarction (STEMI) has been reported to be 2.6%-36%. Excessive inappropriate catheterization lab activation may be associated with risks to patients, provider fatigue and improper resource usage. HYPOTHESIS: To derive and validate a prediction score to more accurately classify patients with STEMI. METHODS AND RESULTS: We conducted a retrospective cohort analysis of 1144 consecutive patients initially diagnosed with STEMI between September 2008 and January 2013...
October 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30340769/gender-identity-hormone-therapy-and-cardiovascular-disease-risk
#18
REVIEW
Claudia Martinez, Rishi Rikhi, Tahir Haque, Amara Fazal, Michael Kolber, Barry E Hurwitz, Neil Schneiderman, Todd T Brown
Transgender individuals represent a medically underserved and under researched population. There is a growing number of studies illustrating the importance of hormone therapy treatments in transgender men and women to assist ameliorating gender dysphoria and promoting well-being. However, the cardiovascular effects of these hormones are controversial. Large longitudinal epidemiological studies of cardiovascular event outcomes in these populations do not exist. In addition, studies of cardiovascular complications of transgender hormone therapy are limited in number and complicated by poor control of medication regimen, presence of gender confirming surgery, use of prescribed medications for prevailing conditions, and alcohol, smoking or illicit substance use, and comorbidities, such as HIV infection...
September 20, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30340770/misunderstood-or-mistrusted-the-under-utilization-of-the-wearable-cardioverter-defibrillator-in-clinical-practice
#19
REVIEW
Pooja S Jagadish, Mariana Aziz, Viswanatha Chinta, Rami N Khouzam
Annually in the United States, sudden cardiac death (including out-of-hospital cardiac arrests) is responsible for over 300,000 deaths, comprising 40%-50% of total mortality rates from cardiovascular disease. Among the highest-risk patients are those with ischemic and nonischemic cardiomyopathy who have a reduced left ventricular ejection fraction (≤ 35%-40%). However, not everyone is a candidate for an implantable cardioverter defibrillator. In 2002, the wearable cardioverter defibrillator (WCD) gained Food and Drug Administration approval for its efficacy in the prevention of sudden cardiac arrest or death in certain at-risk populations and has been making its way into national guidelines with Class IIa to IIb strength of evidence...
September 18, 2018: Current Problems in Cardiology
https://read.qxmd.com/read/30660333/modern-management-of-st-segment-elevation-myocardial-infarction
#20
REVIEW
Jennifer Frampton, James T Devries, Terrence D Welch, Bernard J Gersh
Disruption of intracoronary plaque with thrombus formation resulting in severe or total occlusion of the culprit coronary artery provides the pathophysiologic foundation for ST-segment elevation myocardial infarction (STEMI). Management of STEMI focuses on timely restoration of coronary blood flow along with antithrombotic therapies and secondary prevention strategies. The purpose of this review is to discuss the epidemiology, pathophysiology, and diagnosis of STEMI. In addition, the review will focus on guideline-directed therapy for these patients and review potential associated complications...
September 14, 2018: Current Problems in Cardiology
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