journal
https://read.qxmd.com/read/38908210/necropsy-findings-in-heart-transplant-recipients-with-or-without-primary-graft-dysfunction
#1
REVIEW
Deborah S P Belfort, Sandrigo Mangini, Mônica S Ávila, Fabiana G Marcondes-Braga, Iascara W Campos, Luís Fernando B C Seguro, Fernando Bacal, Paulo S Gutierrez
BACKGROUND: Primary graft dysfunction (PGD) is the leading cause of death in the first year after heart transplant (HT), but pathophysiology and histology are not completely understood. This study describes and compares morphological findings of hearts of patients with and without PGD. METHODS: We included adult patients submitted to HT in a single center who died within the first 14 days after HT and were submitted to necropsy. Clinical and histological data were recorded retrospectively...
June 21, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38908729/semaglutide-and-heart-failure-updated-meta-analysis
#2
REVIEW
Leandro Barbagelata, Walter Masson, Martín Lobo, Ignacio Bluro
BACKGROUND: Heart failure (HF) is a major contributor to global health challenges, affecting mortality rates and healthcare expenditure. Glucagon-like peptide-1 receptor agonists (GLP-1RA) offer promise in HF management, though their precise impact is unclear. The main objective of this study was to evaluate the effect of semaglutide on HF-related outcomes. METHODS: We conducted a meta-analysis of studies assessing the effects of semaglutide therapy on HF-related outcomes...
June 20, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38908728/predictors-and-rate-of-survival-after-out-of-hospital-cardiac-arrest
#3
REVIEW
Anthony Matta, John Philippe, Vanessa Nader, Laszlo Levai, Nicolas Moussallem, Amine Azzi, Patrick Ohlmann
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) is a major public health concern and encloses a wide spectrum of causes. The purpose of this study is to assess predictors and rate of survival at hospital discharge and long-term in the setting of OHCA. The secondary endpoint is to compare OHCA-survival outcomes of presumed ischemic versus non ischemic cause. METHODS: A retrospective cohort was conducted on 318 consecutive patients admitted for OHCA at Civilian Hospitals of Colmar between 2010 and 2019...
June 20, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38908727/a-review-regarding-the-article-impact-of-simulation-based-training-on-transesophageal-echocardiography-learning-a-systemic-review-and-meta-analysis-of-randomized-controlled-trials
#4
REVIEW
Yueqiu Su, Dou Yuan
Transesophageal echocardiography (TEE) has emerged as a critical imaging technique for anesthesiologists, enabling them to monitor and detect significant cardiothoracic conditions in both cardiac and noncardiac surgical patients throughout the perioperative period. Given the expanding applications of TEE, its integration into the anesthesiology residency curriculum at an early stage is crucial. This ensures that residents have ample time to develop their TEE skills, thereby facilitating meaningful clinical application post-residency...
June 20, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38908726/prevention-of-cardiotoxicity-in-childhood-cancer-survivors-in-physical-exercise-we-trust
#5
REVIEW
Valentina Bucciarelli, Francesco Bianco, Giandomenico Bisaccia, Kristian Galanti, Allegra Arata, Mirella Ricci, Benedetta Bucciarelli, Michele Marinelli, Giulia Renda, Alberto Farinetti, Anna Vittoria Mattioli, Sabina Gallina
In recent years, the mean survival rate of children after a cancer diagnosis has significantly improved. At the same time, a growing interest in short and long-term cardiovascular (CV) complications of cancer therapy, as well as long-term CV risk in childhood cancer survivors (CCS) developed, along with proposals of protocols for the diagnosis, management, and prevention of cancer therapy-related CV toxicity (CTR-CVT) in this population. Many clinical and individual risk factors for CTR-CVT have been identified, and a non-negligible prevalence of traditional CV risk factors has been described in this population, potentially associated with a further worsening in both CTR-CVT and long-term CV risk...
June 20, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38876163/five-year-risk-of-all-cause-death-and-cardiovascular-events-in-women-with-gestational-diabetes-and-hypertensive-disorders-of-pregnancy
#6
REVIEW
Tommaso Bucci, Claire L Meek, Silvia Awor, Gregory Y H Lip, Abi Merriel
BACKGROUND: The long-term impact of gestational complications on cardiovascular outcomes in women remains a subject of debate. AIM: To assess the 5-year risk of cardiovascular events and all-cause mortality in women with gestational diabetes and hypertension. METHODS: Retrospective study utilising an health research network(TriNetX). The primary outcome was the composite risk of a cardiovascular event within 5 years with secondary outcomes being its components (all-cause death, acute heart failure, myocardial infarction, ischaemic stroke)...
June 12, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38871039/can-semaglutide-offer-hope-for-patients-with-obesity-related-heart-failure
#7
REVIEW
Gbolahan Olatunji, Nicholas Aderinto, Emmanuel Kokori, Ikponmwosa Jude Ogieuhi, Israel Charles Abraham, Olawale Olanisa, Chikodili Nebuwa, Michael Awoyinfa, Oluwafemi Ajimotokan, Joan Oluwadamilola Ajayi, Nitin Narayan Rao, Ajayi Oluwatomisin Temidayo, Tejiri Napoleon, Owolabi Samuel, Chimezirim Ezeano
Heart failure with preserved ejection fraction (HFpEF) is a growing clinical challenge with limited treatment options. This review explores the potential of semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, for HFpEF treatment. Studies suggest promising benefits, including symptom improvement, weight management, and the potential for enhanced exercise capacity. However, the evidence for semaglutide's impact on exercise capacity and heart function remains inconclusive, and its anti-inflammatory effects require further investigation...
June 11, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38857665/outcomes-after-septal-myectomy-in-a-cohort-of-patients-with-hypertrophic-cardiomyopathy
#8
REVIEW
L V Lopez-Gutierrez, J D Orozco-Burbano, M A Murillo-Moreno, L F Durango-Gutiérrez, P M Hernández-Aramburo, S G González-Franco, E M Cañas Arenas, J C Rendón-Isaza, C I Saldarriaga-Giraldo
UNLABELLED: Hypertrophic cardiomyopathy (HCM) with left ventricular outflow tract obstruction that doesn't improve with pharmacological management often requires septal myectomy. However, there are few centers with experience in the practice of this procedure in our country. We describe the clinical and echocardiographic characteristics and postoperative outcomes of patients with HCM indicated for septal myectomy at a reference center in Colombia. MATERIALS AND METHODS: Retrospective cohort study...
June 8, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38852913/could-the-periodontal-therapy-improve-the-cardiologic-patient-health-a-narrative-review
#9
REVIEW
Carlo Bertoldi, Roberta Salvatori, Marcello Pinti, Anna Vittoria Mattioli
BACKGROUND: Cardiovascular diseases (CVD) is the major cause of mortality globally, with increasing evidence suggesting a link between periodontitis, and CVD. This study aims to explore the association between periodontitis and CVD, and the impact of periodontal therapy on cardiovascular health. METHODS: This review synthesized findings from preclinical and clinical studies, without publication year restrictions, examining periodontitis and CVD through various lenses...
June 7, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38852912/sepsis-and-septic-shock-outcomes-and-90-day-readmissions-in-heart-failure-with-reduced-ejection-fraction-a-national-readmission-database-study
#10
REVIEW
Abdilahi Mohamoud, Nadhem Abdallah, Abdirahman Wardhere, Samira Teeri, Mahmoud Ismayl
BACKGROUND: Patients with heart failure with reduced ejection fraction (HFrEF) are at increased risk for sepsis/septic shock. METHOD: A retrospective study was conducted using the Nationwide Readmission Database (2016-2020). Adult patients admitted with sepsis or septic shock were identified and stratified based on the presence of underlying HFrEF. Multivariable logistic regression assessed the association between HFrEF and in-hospital mortality, 90-day readmission, and other complications...
June 7, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38852911/a-review-regarding-the-article-traditional-chinese-medicine-compound-tongxinluo-and-clinical-outcomes-of-patients-with-acute-myocardial-infarction-the-cts-ami-randomized-clinical-trial
#11
REVIEW
Heng Zhu, Guoqu Jia
Tongxinluo, a traditional Chinese medicine compound, has shown promise in improving outcomes for patients with ST-segment elevation myocardial infarction (STEMI). This randomized, double-blind, placebo-controlled trial investigated the efficacy of Tongxinluo in reducing major adverse cardiac and cerebrovascular events (MACCEs) in STEMI patients. The study enrolled 3777 patients from 124 hospitals in China, all of whom received standard STEMI treatments in addition to either Tongxinluo or placebo for 12 months...
June 7, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38852910/maternal-fetal-dyad-beyond-the-phenomenology-of-pregnancy-from-primordial-cardiovascular-prevention-on-out-do-not-miss-this-boat
#12
REVIEW
Valentina Bucciarelli, Federica Moscucci, Alessandra Dei Cas, Francesca Coppi, Francesco Angeli, Carmine Pizzi, Giulia Renda, Savina Nodari, Silvia Maffei, Roberta Montisci, Roberto Pedrinelli, Susanna Sciomer, Pasquale Perrone Filardi, Anna Vittoria Mattioli, Sabina Gallina
Pregnancy represents a stress test for every woman's cardiovascular (CV) system, and a pre-existing maternal unfavorable cardio-metabolic phenotype can uncover both adverse pregnancy outcomes and the subsequent development of cardiovascular disease (CVD) risk factors during and after pregnancy. Moreover, the maternal cardiac and extracardiac environment can affect offspring's cardiovascular health through a complex mechanism called developmental programming, in which fetal growth can be influenced by maternal conditions...
June 7, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38852909/financial-barriers-to-attending-international-cardiology-conferences-2022-24-analysis-of-registration-fees
#13
REVIEW
Vivek Bhat, Shreyas Bellur, Ashish Kumar, Nandan Anavekar, Ankur Kalra
No abstract text is available yet for this article.
June 7, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38844267/short-term-outcomes-of-endovascular-aortic-aneurysm-repair-with-the-new-braile-biom%C3%A3-dica%C3%A2-total-custom-made-abdominal-endograft-experience-from-three-italian-centers
#14
REVIEW
Antonio Rizza, Angela Buonpane, Cataldo Palmieri, Luca Bastiani, Roberto Prunella, Antonio Fontana, Gaetano La Barbera, Nicola Tusini
INTRODUCTION: Since 2019, Braile Biomédica® introduced a novel custom-made abdominal endograft tailored to the aorta's anatomy, featuring sizing every 3 mm and a diameter change from 50 mm to 8 mm. This design permits uncovered fenestrations around a single Z stent, eliminating the need for bridging stents to visceral vessels. Utilizing triple stent technology, optimal neck fixation is ensured, enabling treatment of necks shorter than 2 mm, with three 360° fenestrations optimizing graft fixation...
June 4, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38830479/microbiome-miracles-and-their-pioneering-advances-and-future-frontiers-in-cardiovascular-disease
#15
REVIEW
Mishal Safdar, Muneeb Ullah, Shah Hamayun, Abdul Wahab, Shahid Ullah Khan, Sidikov Akmal Abdikakhorovich, Zia Ul Haq, Aqsa Mehreen, Muhammad Naeem, Apon Zaenal Mustopa, Nurhasni Hasan
Cardiovascular diseases (CVDs) represent a significant global health challenge, underscoring the need for innovative approaches to prevention and treatment. Recent years have seen a surge in interest in unraveling the complex relationship between the gut microbiome and cardiovascular health. This article delves into current research on the composition, diversity, and impact of the gut microbiome on CVD development. Recent advancements have elucidated the profound influence of the gut microbiome on disease progression, particularly through key mediators like Trimethylamine-N-oxide (TMAO) and other microbial metabolites...
June 1, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38823526/practice-patterns-of-rate-control-in-atrial-fibrillation-and-clinical-outcomes-from-a-nationwide-cohort
#16
REVIEW
William Frick, Zidong Zhang, Lanerica Rogers, Chaitanya Rojulpote, Chien-Jung Lin
Atrial fibrillation (AF) is common, but limited data to guide selection of rate control medication (RCM). Reasons for selection are multivariable, and the impact on outcomes is unknown. We investigated prescribing patterns of RCM among patients with AF. Using a nationwide database, we identified 135,927 patients with AF. We stratified by baseline presence of heart failure with reduced ejection fraction (HFrEF) and examined prescription rates of RCM as a function of clinical variables. We also evaluated associations with clinical outcomes...
May 30, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38820919/the-various-perioperative-issues-of-structural-heart-diseases-and-cardiogenic-shock
#17
REVIEW
Claudia Lama von Buchwald, Ahmad Jabri, Raef Fadel, Laith Alhuneafat, Dee Dee Wang, Enrique Mariscal, Mohammad Alqarqaz, Pedro Engel, Brian O'Neill, Tiberio Frisoli, James Lee, Amr Abbas, William W O'Neill, Pedro A Villablanca
Up to 20 % of patients presenting with acute heart failure and cardiogenic shock have a structural etiology. Despite efforts in timely management, mortality rates remain alarmingly high, ranging from 50 % to 80 %. Surgical intervention is often the definitive treatment for structural heart disease; however, many patients are considered high risk or unsuitable candidates for such procedures. Consequently, there has been a paradigm shift towards the development of novel percutaneous management strategies and temporizing interventions...
May 30, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38821235/a-review-regarding-the-article-basal-natriuresis-as-a-predictor-of-diuretic-resistance-and-clinical-evolution-in-acute-heart-failure
#18
REVIEW
Ke Li, Rui Shi, Lian Luo
Acute heart failure (AHF) is characterized by the emergence or intensification of symptoms and signs indicative of congestion or systemic hypoperfusion, stemming from an underlying structural or functional cardiac disorder. Intravenous loop diuretics play a pivotal role in achieving effective decongestion and ensuring clinical stability; the efficacy of these medications is crucial for determining the patient's hospital course and early outpatient progression. Individuals who exhibit a suboptimal response to diuretics or develop diuretic resistance (DR) are at an elevated risk for cardiovascular mortality and readmission due to AHF...
May 29, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38821234/effectiveness-of-integrated-palliative-care-telehealth-intervention-in-patients-with-chronic-heart-failure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
REVIEW
Sneha Annie Sebastian, Yash Shah, Camelia Arsene
BACKGROUND: Heart failure (HF) represents a substantial burden, impacting both health and financial domains. Despite the presence of evidence-based interventions for prevention and management, suboptimal care has been recognized as a critical contributor to adverse HF-related outcomes. We aim to analyze the impact of palliative care telehealth intervention compared to usual care in quality of life (QoL) and resource utilization of chronic HF patients. METHODS: We conducted a systematic search across various databases, including MEDLINE (via PubMed), Google Scholar, the Cochrane Library, and ScienceDirect to identify randomized controlled trials (RCTs) examining the impact of palliative care telehealth interventions on the QoL and health outcomes of HF patients from inception until May 2024...
May 29, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38821233/is-peritoneal-dialysis-superior-to-hemodialysis-regarding-outcomes-in-end-stage-renal-disease-patients-with-st-segment-elevation-myocardial-infarction-insights-from-the-national-inpatient-sample-database-2016-2020
#20
REVIEW
Muhammad Ibraiz Bilal, Rohan Gajjar, Adeel Nasrullah, Kenneth Matthew Zabel, Siri Vummanen, Aniesh Bobba, Abu Baker Sheikh, Neha Yadav
End-stage renal disease (ESRD) patients are at increased risk of mortality, particularly due to cardiovascular events such as acute myocardial infarction. Hemodialysis and peritoneal dialysis are the two main treatment modalities for ESRD patients. Using data from the National Inpatient Sample (NIS) database, we conducted a retrospective study involving 25,435 ESRD patients diagnosed with ST-elevation myocardial infarction (STEMI) between 2016 and 2020, categorized by their dialysis regimen. Our analysis revealed comparable mortality rates between peritoneal dialysis (PD) and hemodialysis (HD) patients, but lower hospitalization costs and fewer complications among PD recipients...
May 29, 2024: Current Problems in Cardiology
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