Diane M Wilcock, Kristina H Moore, Leslie Rowe, Jonathan Mahlow, Jolanta Jedrzkiewicz, Allison S Cleary, Lesley Lomo, Ana L Ruano, Maarika Gering, Derek Bradshaw, Meghan Maughan, Phuong Tran, Jesse Burlingame, Richard Davis, Kajsa Affolter, Daniel J Albertson, Parisa Adelhardt, Jong Take Kim, Joshua F Coleman, Georgios Deftereos, Evin H Gulbahce, Deepika Sirohi
CONTEXT.—: Quantitative imaging is a promising tool that is gaining wide use across several areas of pathology. Although there has been increasing adoption of morphologic and immunohistochemical analysis, the adoption for evaluation of fluorescence in situ hybridization (FISH) on formalin-fixed, paraffin-embedded tissue has been limited because of complexity and lack of practice guidelines. OBJECTIVE.—: To perform HER2 FISH validation in breast carcinoma in accordance with the American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) 2018 guideline...
March 15, 2023: Archives of Pathology & Laboratory Medicine