Paul W Kline, Faisal D Shaikh, Jaclyn E Tennant, Renee Hamel, Lisa A Zukowski
INTRODUCTION: To determine if demographic variables and measures of cognitive function, functional mobility, self-reported balance self-efficacy, and self-reported physical activity can predict gait speed variability during single-task walking (STgscv), during cognitive-motor dual-tasking (DTgscv), and dual-task effect on gait speed variability (DTEgscv) in older adults. METHODS: In 62 older adults, demographics were recorded and cognitive function (including the Montreal Cognitive Assessment, MoCA), functional mobility, balance self-efficacy (Activity-Specific Balance Confidence Scale, ABC), and self-reported physical activity (Physical Activity Scale for the Elderly, PASE) were assessed...
April 20, 2024: Gerontology
Yuen-Ting Wong, Stewart Morrison
INTRODUCTION: Footcare is an important component of wellbeing in older adults and the promotion of appropriate footcare interventions is imperative for health professionals working with this population. In this scoping review, we describe the health promotion models informing footcare interventions for older people. The objectives were to (i) understand the context(s) where health promotion models have informed footcare interventions; (ii) identify the health promotion models informing interventions; and (iii) document the effectiveness of theoretically informed health promotion interventions for improving footcare in older adults...
April 18, 2024: Gerontology
Hylton B Menz, Shan M Bergin, Jodie A McClelland, Shannon E Munteanu
INTRODUCTION: Several footwear characteristics have been shown to affect balance and gait patterns and may therefore influence the risk of falling in older adults. However, attributing a link between footwear and falls is inherently difficult as it often relies on self-report which may be inaccurate. METHODS: Archival video recordings of falls that occurred in two long-term residential aged care facilities were initially screened to determine whether the footwear worn at the time (barefoot, socks, slippers/sandals, or shoes) could be documented...
April 16, 2024: Gerontology
Franziska Podesser, Johannes Weninger, Elisabeth M Weiss, Josef Marksteiner, Markus Canazei
INTRODUCTION: Dementia increases the risk of falls and fall-related injuries, which may be caused by inappropriate medication use. To date, there is little evidence on which medications are more likely to cause falls. We therefore investigated the effects of medication use and medication changes 48 hours before falls in hospitalised patients with dementia. METHODS: This matched case-control study included 74 patients with a mean age of 83 years (38% women) who had been hospitalised for at least 7 days...
April 16, 2024: Gerontology
Lee Butcher, Jose A Carnicero, Karine Pérès, Stefania Bandinelli, Francisco Jose García-García, Fernando Rodriguez-Artalejo, Leocadio Rodriguez-Mañas, Jorge D Erusalimsky
INTRODUCTION: Frailty is prevalent among older adults with diabetes mellitus. Elevated serum levels of the soluble receptor for advanced glycation-end products (sRAGE) predict mortality in frail older adults. The evidence that sRAGE is also related to higher mortality in older adults with diabetes mellitus is inconsistent. Therefore, this study explored if frailty status influences the relationship between sRAGE and mortality in older adults with this condition. METHODS: We analysed data of 391 participants with diabetes mellitus (median age, 76 years) from four European cohorts enrolled in the FRAILOMIC project...
April 9, 2024: Gerontology
Shugo Yajima, Yasukazu Nakanishi, Ryo Andy Ogasawara, Naoki Imasato, Kohei Hirose, Sao Katsumura, Madoka Kataoka, Hitoshi Masuda
INTRODUCTION: The aim of this study is to evaluate the features and benefits of different geriatric screening tools for enhancing the perioperative care of patients who undergo elective cancer surgery using cluster analysis. METHODS: This study was a retrospective, observational analysis of 1019 consecutive patients who had elective major cancer surgery in the urology department of our hospital from October 2019 to January 2023. Before the surgery, a trained nurse screened the patients using six tools: Eastern Clinical Oncology Group performance status (ECOG-PS), flemish version of the triage risk screening tool (fTRST), geriatric-8 (G8), instrumental activities of daily living (IADL), patient health questionnaire-2 (PHQ-2), and simple questionnaire to rapidly diagnose sarcopenia (SARC-F)...
April 5, 2024: Gerontology
Ivan Baltasar-Fernandez, Hector Soto-Paniagua, Julian Alcazar, María Isabel Uceta Espinosa, Luis M Alegre, Francisco José Gracía-García, Ignacio Ara, Ana Alfaro Acha, Jose Losa-Reyna
INTRODUCTION: Concurrent training has been shown to be a beneficial approach to improve overall health status in older adults. However, little is known about the adaptations of this type of training in the long term (i.e., after cessation of exercise), even less in older people affected by frailty syndrome.Therefore, this study aimed i) to assess the effects of a 6-week concurrent training program composed of power-oriented resistance training (RT) and fast walking interval training (FWIT) on physical function, muscle power, disability in activities of daily living and frailty in pre-frail and frail older people, and ii) to assess the effects of a 6-month detraining period on these outcomes...
April 4, 2024: Gerontology
Tae Sung Lee, Hyuck Min Kwon, Jun Young Park, Min Cheol Park, Yong Seon Choi, Kwan Kyu Park
INTRODUCTION: The purpose of this study was to evaluate peripheral nerve block (PNB) effectiveness on postoperative pain management and surgical outcomes for displaced femoral-neck fracture in geriatric patients (>70 years) who underwent bipolar hemiarthroplasty (BHA). METHODS: From January 2017 to December 2021, 231 geriatric patients with displaced femoral-neck fracture who consecutively underwent BHA were retrospectively reviewed. Patients were divided into two groups: patient-controlled analgesia (PCA) group (n=132) who received only intravenous (IV) PCA for postoperative pain management, and all others who received PNB with IV PCA (PNB+PCA) such as femoral nerve block or fascia iliaca compartment block after surgery (n=99)...
April 4, 2024: Gerontology
Peng Liu, Linxi Chen, Xinwei He, Lingqun Mao
INTRODUCTION: Parkinson's disease (PD) is characterized by a prodromal phase preceding the onset of classic motor symptoms. The duration and clinical manifestations of prodromal PD vary widely, indicating underlying heterogeneity within this stage. This discrepancy prompts the question of whether specific factors contribute to the divergent rates of progression in prodromal PD. METHODS: This study included prodromal PD patients from the Parkinson's Progression Markers Initiative...
April 2, 2024: Gerontology
Manne Godhe, Gustaf Rönquist, Johnny Nilsson, Örjan Ekblom, Lillemor Nyberg, Gunnar Edman, Eva Andersson
INTRODUCTION: Physical fitness is strongly associated with daily physical function, health, and longevity in older adults. Field-based tests may provide a reasonable alternative compared to advanced laboratory testing. Separating post-exercise test-scores from reactivity measurements requires sufficient test-retest reliability. Post-exercise test-scores with reliability-analyses of field-based fitness-tests in older adults are lacking. The present study aimed to examine the test-retest-reliability of some novel easily accommodated fitness-test-measurements and compare pre-test scores with post-exercise results in these tests along with other field-based fitness tests in older adults...
April 2, 2024: Gerontology
Natalie Hezel, Leon Brüll, Adamantios Arampatzis, Michael Schwenk
INTRODUCTION: Perturbation-based balance training is promising for fall prevention in older adults mimicking real-life fall situations at a person's stability thresholds to improve reactive balance. Hence, it can be associated with anxiety, but knowledge about the acceptability of perturbation-based balance training is scarce. METHOD: This is a secondary analysis of a randomized controlled trial comparing effects of two different perturbation-based balance training paradigms that aims to evaluate and compare the acceptability of those training paradigms in fall-prone older adults...
April 2, 2024: Gerontology
Mutsumi Suganuma, Motoki Furutani, Tohru Hosoyama, Risa Mitsumori, Rei Otsuka, Marie Takemura, Yasumoto Matsui, Yukiko Nakano, Shumpei Niida, Kouichi Ozaki, Shosuke Satake, Daichi Shigemizu
INTRODUCTION: Although frailty is a geriatric syndrome that is associated with disability, hospitalization, and mortality, it can be reversible and preventable with the appropriate interventions. Additionally, as the current diagnostic criteria for frailty include only physical, psychological, cognitive and social measurements, there is a need for promising blood-based molecular biomarkers to aid in the diagnosis of frailty. METHODS: To identify candidate blood-based biomarkers that can enhance current diagnosis of frailty, we conducted a comprehensive analysis of clinical data, messenger RNA sequencing (RNA-seq), and aging-related factors using a total of 104 older adults aged 65-90 years (61 frail subjects and 43 robust subjects) in a cross-sectional case-control study...
March 14, 2024: Gerontology
Xiao-Hong Liu, Qing-Fu Zhang, Xiao-Qi Zhang, Qing-Wang Lu, Jian-Hua Wu, Xiao-Hua Gao, Zhi-Yuan Chen
INTRODUCTION: We analyzed the effect of dexmedetomidine (DEX) as a local anesthetic adjuvant on postoperative delirium (POD) in elderly patients undergoing elective hip surgery. METHODS: In this study, 120 patients undergoing hip surgery were enrolled and randomly assigned to two groups: fascia iliaca compartment block with DEX + ropivacaine (the Y group, n = 60) and fascia iliaca compartment block with ropivacaine (the R group, n = 60). The primary outcomes: presence of delirium during the postanesthesia care unit (PACU) period and on the first day (D1), the second day (D2), and the third day (D3) after surgery...
March 13, 2024: Gerontology
Weihao Xu, Anying Bai, Yuanfeng Liang, Zhanyi Lin
Background Epidemiologic studies have indicated an association of Motoric Cognitive Risk syndrome (MCR), a pre-dementia stage characterized by the presence of cognitive complaints and a slow gait, with increased risk of incident dementia. Objectives We aimed to clarify this association using meta-analysis. Methods We systematically searched the PubMed, Embase, and Web of Science databases up to December 2022 for relevant studies that investigated the association between MCR and incident all-cause dementia and Alzheimer's disease (AD)...
March 8, 2024: Gerontology
Xin Xia, Zhongli Yang, Zhigang Xu, Jingyi Tang, Gongchang Zhang, Birong Dong, Xiaolei Liu
Introduction Although the relationship between the number of teeth and frailty has been extensively studied, the mediating role of nutrition status in the association between the number of teeth and frailty remains to be clarified. Methods A number of 6664 participates lived in the communities of West China were analyzed in our study. Physical frailty was determined based on the phenotype established by Fried. Nutrition status was evaluated using the Mini Nutrition Assessment-Short Form (MNA-SF) scale. Multiple linear regression was employed to evaluate the direct relationships between the number of teeth, nutrition, and frailty...
March 8, 2024: Gerontology
Sijia Li, Ying Tang, You Zhou, Yunxia Ni
INTRODUCTION: Noninvasive brain stimulation (NIBS) has shown benefits for cognitive function in older adults. However, the effects of transcranial direct current stimulation (tDCS) on cognitive function in older adults are inconsistent across studies, and the evidence for tDCS has limitations. We aim to explore whether tDCS can improve cognitive function and different cognitive domains (i.e., learning and memory and executive function) in adults aged 65 and older with and without mild cognitive impairment and to further analyze the influencing factors of tDCS...
March 7, 2024: Gerontology
Kate Curtis, John McKenzie, Geoffrey Melville, Peter Moules, Cayce Wylie, Alexandra Tyler, Bridie Mulholland
BACKGROUND: Hip fracture in older adults results in significant mortality and is one of the costliest fall-related injuries. The Australian Commission for Quality and Safety in Health Care hip fracture clinical care standards consolidate the best available evidence for managing this patient group however uptake is variable. The aim of this study was to evaluate the implementation and effectiveness of a multidisciplinary early activation mechanism and bundle of care (eHIP) on patient and health service outcomes...
March 7, 2024: Gerontology
Shoma Akaida, Yoshiaki Taniguchi, Yuki Nakai, Yuto Kiuchi, Mana Tateishi, Daijo Shiratsuchi, Toshihiro Takenaka, Takuro Kubozono, Mitsuru Ohishi, Hyuma Makizako
Introduction Although arterial stiffness has been suggested to be associated with poor physical function and mild cognitive impairment (MCI), its association with cognitive frailty (CF), a comorbidity of both, is unclear. This study aims to examine the association between CF and arterial stiffness in community-dwelling older adults. Methods A cross-sectional analysis of 511 community-dwelling older adults aged 65 years or older (mean age 73.6 ± 6.2 years, 63.6% women), who participated in a community cohort study (Tarumizu Study, 2019), was conducted...
February 26, 2024: Gerontology
Chris F Duncan, Dagan O Lonsdale, Helen Farrah, Sarah Farnell-Ward, Christine Ryan, Ximena Watson, Maurizio Cecconi, Jesper Fjølner, Wojciech Szczeklik, Rui Moreno, Antonio Artigas, Michael Joannidis, Dylan W De Lange, Bertrand Guidet, Hans Flaatten, Christian Jung, Susannah Leaver
INTRODUCTION: Cases of major trauma in the very old (over 80 years) are increasingly common in the intensive care unit. Predicting outcome is challenging in this group of patients as chronological age is a poor marker of health and poor predictor of outcome. Increasingly, decisions are guided with the use of organ dysfunction scores of both the acute condition (e.g. Sequential Organ Failure Assessment (SOFA) score) and chronic health issues (e.g. clinical frailty scale, (CFS)). Recent work suggests that increased CFS is associated with a worse outcome in elderly major trauma patients...
February 22, 2024: Gerontology
Danielle D'Amico, Udi Alter, Danielle Laurin, Guylaine Ferland, Alexandra J Fiocco
INTRODUCTION: The objective of this study was to examine whether a healthy lifestyle composite score of social engagement, physical activity, and Mediterranean diet adherence moderates the association between psychological distress and global cognitive decline among cognitively healthy older adults (67+ years of age at baseline). METHODS: A total of 1,272 cognitively intact older adults (Mage = 74.1±4.1 years, 51.9% female) in the Quebec Longitudinal Study on Nutrition and Successful Aging (NuAge) completed a series of self-reported questionnaires to measure psychological distress and lifestyle behaviours, and the Modified Mini-Mental Examination (3MS) to assess cognitive performance at baseline and annually over 3 years...
February 14, 2024: Gerontology
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