journal
https://read.qxmd.com/read/37718285/epidemiological-characteristics-of-centenarian-deaths-in-china-during-2013-2020-a-trend-and-subnational-analysis
#1
JOURNAL ARTICLE
Fan Mao, Weiwei Zhang, Peng Yin, Lijun Wang, Jinling You, Jiangmei Liu, Yunning Liu, Maigeng Zhou
BACKGROUND: Studies that comprehensively address the characteristics of centenarian deaths are rare. The present study aimed to examine the characteristics of centenarian deaths in China and their changing trends. METHODS: Data on centenarian deaths between 2013 and 2020 were obtained from the national mortality surveillance system of China, including date, place of death (PoD), and underlying cause of death (CoD). Descriptive analyses were performed to understand the epidemiological characteristics, and a joinpoint regression model was adopted to examine the changing trends in the proportions of different PoDs, CoDs, and centenarian deaths accounting for all deaths and deaths among people aged 65 years and older...
September 15, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37718264/prognostic-and-clinical-value-of-circprkci-expression-in-diverse-human-cancers
#2
JOURNAL ARTICLE
Zhongyue Liu, Xiaolei Ren, Zhimin Yang, Lin Mei, Wenyi Li, Chao Tu, Zhihong Li
BACKGROUND: Highly expressed in various human cancers, circular RNA Protein Kinase C Iota (circPRKCI) has been reported to play an important role in cancer development and progression. Herein, we sought to reveal the prognostic and clinical value of circPRKCI expression in diverse human cancers. METHODS: We searched the Pubmed, Web of Science, and the Cochrane Library databases from inception until May 16, 2021. The relationship between circPRKCI expression and cancer patients' survival, including overall survival (OS) and disease-free survival (DFS), was assessed by pooled hazard ratios (HR) with corresponding 95% confidence interval (CI)...
September 15, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37698022/global-regional-and-national-burden-of-hypertensive-heart-disease-among-older-adults-in-204-countries-and-territories-between-1990-and-2019-a-trend-analysis
#3
JOURNAL ARTICLE
Ruixue Yang, Xun Zhang, Jingjing Bai, Lu Wang, Wenjie Wang, Jun Cai
BACKGROUND: Hypertensive heart disease (HHD) poses a public health challenge, but data on its burden and trends among older adults are scarce. This study aimed to identify trends in the burden of HHD among older adults between 1990 and 2019 at the global, regional, and national levels. METHODS: Using the Global Burden of Diseases study 2019 data, we assessed HHD prevalence, death, and disability-adjusted life-year (DALY) rates for individuals aged 60-89 years at the global, regional, and national levels and estimated their average annual percentage changes (AAPCs) between 1990 and 2019 using joinpoint regression analysis...
September 12, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37697951/shared-and-distinct-abnormalities-of-brain-magnetization-transfer-ratio-in-schizophrenia-and-major-depressive-disorder-a-comparative-voxel-based-meta-analysis
#4
JOURNAL ARTICLE
Huan Lan, Xueling Suo, Chao Zuo, Weishi Ni, Song Wang, Graham J Kemp, Qiyong Gong
BACKGROUND: Patients with schizophrenia (SCZ) and major depressive disorder (MDD) share significant clinical overlap, although it remains unknown to what extent this overlap reflects shared neural profiles. To identify the shared and specific abnormalities in SCZ and MDD, we performed a whole-brain voxel-based meta-analysis using magnetization transfer imaging, a technique that characterizes the macromolecular structural integrity of brain tissue in terms of the magnetization transfer ratio (MTR)...
September 8, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37690994/a-genetic-variant-in-the-immune-related-gene-erap1-affects-colorectal-cancer-prognosis
#5
JOURNAL ARTICLE
Danyi Zou, Yimin Cai, Meng Jin, Ming Zhang, Yizhuo Liu, Shuoni Chen, Shuhui Yang, Heng Zhang, Xu Zhu, Chaoqun Huang, Ying Zhu, Xiaoping Miao, Yongchang Wei, Xiaojun Yang, Jianbo Tian
BACKGROUND: Findings on the association of genetic factors and colorectal cancer (CRC) survival are limited and inconsistent, and revealing the mechanism underlying their prognostic roles is of great importance. This study aimed to explore the relationship between functional genetic variations and the prognosis of CRC and further reveal the possible mechanism. METHODS: We first systematically performed expression quantitative trait locus (eQTL) analysis using The Cancer Genome Atlas (TCGA) dataset...
September 8, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37690993/18f-prostate-specific-membrane-antigen-positron-emission-tomography-computerized-tomography-for-lymph-node-staging-in-medium-high-risk-prostate-cancer-a-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Zhengtong Lv, Liuqi Song, Miao Wang, Huimin Hou, Haodong Li, Xuan Wang, Jianye Wang, Jianlong Wang, Ming Liu
BACKGROUND: Lymph node staging of prostate cancer (PCa) is important for planning and monitoring of treatment. 18F-prostate specific membrane antigen positron emission tomography/computerized tomography (18F-PSMA PET/CT) has several advantages over 68Ga-PSMA PET/CT, but its diagnostic value requires further investigation. This meta-analysis focused on establishing the diagnostic utility of 18F-PSMA PET/CT for lymph node staging in medium/high-risk PCa. METHODS: We searched the EMBASE, PubMed, Cochrane library, and Web of Science databases from inception to October 1, 2022...
September 8, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37690992/chinese-medical-association-consensus-for-standardized-diagnosis-and-treatment-of-pancreatic-neuroendocrine-neoplasms
#7
JOURNAL ARTICLE
Feng Jiao, Jiujie Cui, Deliang Fu, Qi Li, Zheng Wu, Zan Teng, Hongmei Zhang, Jun Zhou, Zhihong Zhang, Xiaobing Chen, Yuhong Zhou, Yixiong Li, Yiping Mou, Renyi Qin, Yongwei Sun, Gang Jin, Yuejuan Cheng, Jian Wang, Gang Ren, Jiang Yue, Guangxin Jin, Xiuying Xiao, Liwei Wang
No abstract text is available yet for this article.
September 8, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37678334/clinical-characteristics-and-genetic-mutations-of-10-chinese-children-with-cystic-fibrosis-and-cystic-frbrosis-transmembrane-conductance-regulator-related-disorders
#8
JOURNAL ARTICLE
Shanshan Tan, Ling Cao
No abstract text is available yet for this article.
September 7, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37678331/peri-procedural-myocardial-injury-predicts-poor-short-term-prognosis-after-tavr-a-single-center-retrospective-analysis-from-china
#9
JOURNAL ARTICLE
Qi Liu, Kaiyu Jia, Yijun Yao, Yijian Li, Tianyuan Xiong, Fei Chen, Yuanweixiang Ou, Xi Wang, Yujia Liang, Xi Li, Yong Peng, Jiafu Wei, Sen He, Qiao Li, Wei Meng, Guo Chen, Wenxia Zhou, Mingxia Zheng, Xuan Zhou, Yuan Feng, Mao Chen
No abstract text is available yet for this article.
September 7, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37677929/global-and-national-burden-of-atherosclerosis-from-1990-to-2019-trend-analysis-based-on-the-global-burden-of-disease-study-2019
#10
JOURNAL ARTICLE
Weihua Chen, Zeya Li, Yu Zhao, Yitian Chen, Rongchong Huang
BACKGROUND: Atherosclerosis-related diseases represent significant health issues among adults globally. Despite their widespread impact, comprehensive data concerning the global and national burden and trends of these diseases remain sparse. Our objective is to examine the trends in the burden of atherosclerosis among adults from 1990 to 2019 at both global and national levels. METHODS: We reported the average annual percentage changes (AAPCs) in prevalence, incidence, mortality, and disability-adjusted life years (DALYs) of atherosclerosis-related diseases (ischemic heart disease [IHD], ischemic stroke, and peripheral arterial disease [PAD]) at the global and national levels among individuals based on a trend analysis of the Global Burden of Diseases Study (GBD) 2019...
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37668091/role-of-ferroptosis-in-fibrosis-from-mechanism-to-potential-therapy
#11
JOURNAL ARTICLE
Xuemeng Qiu, Qing Bi, Jiyue Wu, Zejia Sun, Wei Wang
Fibrosis, which is a manifestation of the physiological response to injury characterized by excessive accumulation of extracellular matrix components, is a ubiquitous outcome of the repair process. However, in cases of repetitive or severe injury, fibrosis may become dysregulated, leading to a pathological state and organ failure. In recent years, a novel form of regulated cell death, referred to as ferroptosis, has been identified as a possible contributor to fibrosis; it is characterized by iron-mediated lipid peroxidation...
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37668076/perspectives-of-genetic-management-strategy-for-inherited-cardiovascular-diseases-in-china
#12
JOURNAL ARTICLE
Yaoyao Zhang, Yanjiang Zheng, Mengyuan Dai, Kaiyu Zhou, Lijun Fu, Yuxuan Guo, Yihua He, Fen Li, Rui Gao, Donghui Zhang, Xujie Liu, Jie Tian, Yimin Hua, Yifei Li, Lang Qin
No abstract text is available yet for this article.
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37668042/functional-gastrointestinal-disorders-mental-health-genetic-susceptibility-and-incident-chronic-kidney-disease
#13
JOURNAL ARTICLE
Mengyi Liu, Panpan He, Ziliang Ye, Sisi Yang, Yanjun Zhang, Qimeng Wu, Chun Zhou, Yuanyuan Zhang, Fan Fan Hou, Xianhui Qin
BACKGROUND: Whether functional gastrointestinal disorders (FGIDs) are associated with the long-term risk of chronic kidney disease (CKD) remains unclear. We aimed to investigate the prospective association of FGIDs with CKD and examine whether mental health mediated the association. METHODS: About 416,258 participants without a prior CKD diagnosis enrolled in the UK Biobank between 2006 and 2010 were included. Participants with FGIDs (including irritable bowel syndrome [IBS], dyspepsia, and other functional intestinal disorders [FIDs; mainly composed of constipation]) were the exposure group, and non-FGID participants were the non-exposure group...
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37668021/a-12-month-follow-up-study-of-discharged-patients-with-acute-pancreatitis-an-acute-condition-with-prolonged-sequela
#14
JOURNAL ARTICLE
Hanyue Ding, Jiayuan Dai, Jiaye Lin, Liang Gong, Han Sun, Kai Song, Feng Xie, Dong Wu
No abstract text is available yet for this article.
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37668004/complete-fracture-of-posterior-cortex-increases-the-risk-of-avascular-necrosis-after-osteosynthesis-for-non-displaced-femoral-neck-fractures-in-elderly-patients
#15
JOURNAL ARTICLE
Hangyu Gu, Qianqian Wang, Minghui Yang, Xinbao Wu, Faming Tian, Shiwen Zhu
No abstract text is available yet for this article.
September 5, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37660289/molecular-classification-of-small-cell-lung-cancer-subtypes-characteristics-prognostic-factors-and-clinical-translation
#16
JOURNAL ARTICLE
Hanfei Guo, Wenqian Li, Ye Guo, Naifei Chen, Jiuwei Cui
Small cell lung cancer (SCLC) is a highly malignant tumor with a very poor prognosis; therefore, more effective treatments are urgently needed for patients afflicted with the disease. In recent years, emerging molecular classifications based on key transcription factors of SCLC have provided more information on the tumor pathophysiology, metastasis, immune microenvironment, and acquired therapeutic resistance and reflected the intertumoral heterogeneity of the various SCLC phenotypes. Additionally, advances in genomics and single-cell sequencing analysis have further revealed the high intratumoral heterogeneity and plasticity of the disease...
September 1, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37660288/robotic-surgical-systems-in-plastic-and-reconstructive-surgery
#17
JOURNAL ARTICLE
Junxian Wen, Nanze Yu, Xiao Long, Xiaojun Wang
No abstract text is available yet for this article.
September 1, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37660287/association-of-interpregnancy-interval-and-risk-of-adverse-pregnancy-outcomes-in-woman-of-different-previous-gestational-ages
#18
JOURNAL ARTICLE
Peiran Chen, Yi Mu, Zheng Liu, Yanping Wang, Xiaohong Li, Li Dai, Qi Li, Mingrong Li, Yanxia Xie, Juan Liang, Jun Zhu
BACKGROUND: With an increasing proportion of multiparas, proper interpregnancy intervals (IPIs) are urgently needed. However, the association between IPIs and adverse perinatal outcomes has always been debated. This study aimed to explore the association between IPIs and adverse outcomes in different fertility policy periods and for different previous gestational ages. METHODS: We used individual data from China's National Maternal Near Miss Surveillance System between 2014 and 2019...
September 1, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37650127/genome-wide-methylation-profiling-identified-methylated-kcna3-and-otop2-as-promising-diagnostic-markers-for-esophageal-squamous-cell-carcinoma
#19
JOURNAL ARTICLE
Yan Bian, Ye Gao, Chaojing Lu, Bo Tian, Lei Xin, Han Lin, Yanhui Zhang, Xun Zhang, Siwei Zhou, Kangkang Wan, Jun Zhou, Zhaoshen Li, Hezhong Chen, Luowei Wang
BACKGROUND: Early detection of esophageal squamous cell carcinoma (ESCC) can considerably improve the prognosis of patients. Aberrant cell-free DNA (cfDNA) methylation signatures are a promising tool for detecting ESCC. However, available markers based on cell-free DNA methylation are still inadequate. This study aimed to identify ESCC-specific cfDNA methylation markers and evaluate the diagnostic performance in the early detection of ESCC. METHODS: We performed whole-genome bisulfite sequencing (WGBS) for 24 ESCC tissues and their normal adjacent tissues...
August 31, 2023: Chinese Medical Journal
https://read.qxmd.com/read/37649421/research-progress-in-the-mechanism-and-treatment-of-osteosarcoma
#20
JOURNAL ARTICLE
Jichao Bian, Yang Liu, Xiaowei Zhao, Chunyang Meng, Yuanmin Zhang, Yangmiao Duan, Guodong Wang
Osteosarcoma (OS) is the most common primary malignant bone tumor that more commonly occurs in children and adolescents. The most commonly used treatment for OS is surgery combined with chemotherapy, but the treatment outcomes are typically unsatisfactory. High rates of metastasis and post-treatment recurrence rates are major challenges in the treatment of OS. This underlines the need for studying the in-depth characterization of the pathogenetic mechanisms of OS and development of more effective therapeutic modalities...
August 31, 2023: Chinese Medical Journal
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