journal
https://read.qxmd.com/read/38613216/dawn-of-car-t-cell-therapy-in-autoimmune-diseases
#1
JOURNAL ARTICLE
Yuxin Liu, Minghao Dong, Yunhui Chu, Luoqi Zhou, Yunfan You, Xiaowei Pang, Sheng Yang, Luyang Zhang, Lian Chen, Lifang Zhu, Jun Xiao, Wei Wang, Chuan Qin, Daishi Tian
Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in the treatment of hematological malignancies. Based on the immunomodulatory capability of CAR-T cells, efforts have turned toward exploring their potential in treating autoimmune diseases. Bibliometric analysis of 210 records from 128 academic journals published by 372 institutions in 40 countries/regions indicates a growing number of publications on CAR-T therapy for autoimmune diseases, covering a range of subtypes such as systemic lupus erythematosus, multiple sclerosis, among others...
April 12, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38613214/prevalence-and-risk-evaluation-of-cardiovascular-disease-in-the-newly-diagnosed-prostate-cancer-population-in-china-a-nationwide-multi-center-population-based-cross-sectional-study
#2
JOURNAL ARTICLE
Weiyu Zhang, Huixin Liu, Ming Liu, Shi Ying, Renbin Yuan, Hao Zeng, Zhenting Zhang, Sujun Han, Zhannan Si, Bin Hu, Simeng Wen, Pengcheng Xu, Weimin Yu, Hui Chen, Liang Wang, Zhitao Lin, Tao Dai, Yunzhi Lin, Tao Xu
BACKGROUND: Cardiovascular disease (CVD) has emerged as the leading cause of death from prostate cancer (PCa) in recent decades, bringing a great disease burden worldwide. Men with preexisting CVD have an increased risk for major adverse cardiovascular events when treated with androgen deprivation therapy (ADT). The present study was aimed to explore the prevalence and risk evaluation of CVD among people with newly diagnosed PCa in China. METHODS: Clinical data of newly diagnosed PCa patients were retrospectively collected from 34 centers in China from 2010 to 2022 through convenience sampling...
April 12, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38613206/global-burden-of-vision-loss-attributable-to-household-air-pollution-from-1990-to-2019-a-trend-analysis-and-10-year-prediction
#3
JOURNAL ARTICLE
Cong Li, Zuoqian Jing, Jianbo Shen, Shunming Liu, Lei Liu, Xiaohong Yang, Honghua Yu
No abstract text is available yet for this article.
April 12, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38613200/cuproptosis-a-potential-therapeutic-target-in-clear-cell-renal-cell-carcinoma
#4
JOURNAL ARTICLE
Yuetong Zhao, Jie Li, Xiaojie Lu, Shuang Wu, Yunze Xing, Yaxuan Fang, Bo Yang
No abstract text is available yet for this article.
April 12, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38602180/electroacupuncture-reduced-airway-inflammation-by-activating-somatosensory-sympathetic-pathways-in-allergic-asthmatic-rats
#5
JOURNAL ARTICLE
Hongli Ma, Xiaowen Liu, Huamei Cai, Yun Yan, Weixia Li, Jing Zhao
BACKGROUND: Electroacupuncture (EA) treatment is efficacious in patients with respiratory disorders, although the mechanisms of its action in lung-function protection are poorly understood. This study aimed to explore the neuroanatomical mechanisms of EA stimulation at the BL13 acupoint (Feishu, EA-BL13) improvement in asthma. METHODS: Allergic asthma was induced by intranasal 2.0% ovalbumin (OVA) instillation combined with intraperitoneal injection of the 10.0% OVA...
April 10, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38602155/sglt2-inhibitor-monotherapy-alleviates-hyperglycemia-in-heredity-severe-insulin-resistance-syndrome
#6
JOURNAL ARTICLE
Huixuan Wu, Junaid Iqbal, Long Li, Hongli Jiang, Chen Chao, Meibiao Zhang, Ou Li, Houde Zhou
No abstract text is available yet for this article.
April 10, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38602088/a-multicenter-uroflowmetry-study-of-healthy-women-in-china
#7
JOURNAL ARTICLE
Xiaodong Liu, Lingfeng Meng, Jiawen Wang, Tianming Ma, Benkang Shi, Hai Huang, Qingwei Wang, Min Chen, Limin Liao, Hong Shen, Zhongqing Wei, Yuansong Xiao, Tiejun Pan, Jian Ren, Peng Zhang, Xiaojun Tian, Yaoguang Zhang
No abstract text is available yet for this article.
April 10, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38602084/role-of-submucosal-injection-in-radiofrequency-ablation-of-gastric-low-grade-dysplasia-effects-on-symptoms-and-outcomes
#8
JOURNAL ARTICLE
Xiaotong Niu, Nanjun Wang, Yan Wang, Jia Feng, Longsong Li, Ke Han, Ningli Chai, Enqiang Linghu
BACKGROUND: To date, there is still a lack of standardized management strategies for gastric low-grade dysplasia (LGD), which is a direct neoplastic precancerous lesion and requires specifically superficial destruction. Radiofrequency ablation (RFA) is expected to be an effective method for gastric LGD, but post-RFA pain may affect patients' satisfaction and compliance. The current study aimed to evaluate the value of a submucosal injection prior to RFA (SI-RFA) for postoperative pain and treatment outcomes...
April 10, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595135/ferroptosis-in-chronic-obstructive-pulmonary-disease-from-cellular-mechanisms-to-therapeutic-applications
#9
JOURNAL ARTICLE
Mengli Yan, Shiyu Xu, Han Wang, Shoujin Dong, Chunheng Mo
No abstract text is available yet for this article.
April 9, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595093/b7-h3-in-acute-myeloid-leukemia-from-prognostic-biomarker-to-immunotherapeutic-target
#10
JOURNAL ARTICLE
Xiao Tan, Xiangyu Zhao
B7-H3 (CD276), an immune checkpoint protein of the B7 family, exhibits significant upregulation in solid tumors and hematologic malignancies, exerting a crucial role in their pathophysiology. The distinct differential expression of B7-H3 between tumors and normal tissues and its multifaceted involvement in tumor pathogenesis position it as a promising therapeutic target for tumors. In the context of acute myeloid leukemia (AML), B7-H3 is prominently overexpressed and closely associated with unfavorable prognoses, yet it has remained understudied...
April 9, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595150/corrigendum-2022-chinese-national-clinical-practice-guideline-on-helicobacter-pylori-eradication-treatment
#11
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 8, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595121/inpatient-disease-spectrum-and-clinical-characteristics-of-surgical-disorders-in-pediatric-and-adolescent-gynecology-a-single-institute-study-of-12-years-data-from-china
#12
JOURNAL ARTICLE
He Huang, Siyun Wang, Ruixi Zhan, Ling Yin, Yongchun Hu, Donglai Yang, Yangyang Shi
No abstract text is available yet for this article.
April 8, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595105/non-invasive-estimation-of-pulmonary-hypertension-and-clinical-deterioration-risk-in-pediatric-congenital-heart-disease-development-and-validation-of-predictive-tools
#13
JOURNAL ARTICLE
Ting Wang, Dansha Zhou, Yuqin Chen, Suhua Kuang, Yue Xing, Qijian Yi, Zhengxia Pan, Weibin Xu, Jiao Rao, Yunqi Liu, Guoliang Lu, Ziying Lin, Xiang Li, Yi Xie, Yulong Wu, Peng An, Xiaoxiao Deng, Jiayue He, Jiayi Xie, Chenxi Li, Gang Geng, Daiyin Tian, Enmei Liu, Jingsi Huang, Zhou Fu, Jian Wang
No abstract text is available yet for this article.
April 8, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38595091/identification-of-depressive-symptoms-a-cause-and-effect-based-machine-learning-study
#14
JOURNAL ARTICLE
Tiantian Wang, Zijian Zhang, Xilin Zhang, Chuang Xue, Tingting Cheng
No abstract text is available yet for this article.
April 8, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38570199/exosomes-in-malignant-pleural-effusions-sources-and-applications
#15
JOURNAL ARTICLE
Yueyu Huang, Jiahui Wang, Qifeng Yao, Xuping Yang, Xuemei Ye, Junping Liu, Changchun Wang, Bin Zhou, Shuang Li, Bin Su, Weimin Mao, An Zhao
No abstract text is available yet for this article.
April 3, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38570196/chinese-expert-consensus-on-integrated-case-management-by-a-multidisciplinary-team-in-car-t-cell-therapy-for-lymphoma
#16
JOURNAL ARTICLE
Sanfang Tu, Ping Li, Heng Mei, Yang Liu, Yongxian Hu, Peng Liu, Dehui Zou, Ting Niu, Kailin Xu, Li Wang, Jianmin Yang, Mingfeng Zhao, Xiaojun Huang, Jianxiang Wang, Yu Hu, Weili Zhao, Depei Wu, Jun Ma, Wenbin Qian, Weidong Han, Yuhua Li, Aibin Liang
No abstract text is available yet for this article.
April 3, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38563217/reduced-macular-thickness-and-vascular-density-in-abnormal-glucose-metabolism-patients-a-meta-analysis-of-optical-coherence-tomography-oct-and-oct-angiography-studies
#17
JOURNAL ARTICLE
Xiangyu Fu, Xiang Ren, Wenyue Chen, Danian Chen
BACKGROUND: Alterations in macular thickness and vascular density before clinically visible diabetic retinopathy (DR) remain inconclusive. This study aimed to determine whether retinal manifestations in abnormal glucose metabolism (AGM) patients differ from those in the healthy individuals. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 Statement was followed as our guideline for this meta-analysis. PubMed, Embase, and Web of Science were searched between 2000 and 2021...
April 2, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38557962/long-non-coding-rna-malat1-in-hematological-malignancies-and-its-clinical-applications
#18
JOURNAL ARTICLE
Chunlan Zhang, Yun Qin, Yu Wu, Heng Xu, Yang Shu
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a well-established oncogenic long non-coding RNA, the higher expression of which is strongly correlated with cancer events such as tumorigenesis, progression, metastasis, drug resistance, and treatment outcome in solid cancers. Recently, a series of studies has highlighted its potential role in hematological malignancies in terms of these events. Similar to solid cancers, MALAT1 can regulate various target genes via sponging and epigenetic mechanisms, but the miRNAs sponged by MALAT1 differ from those identified in solid cancers...
April 1, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38557731/targeted-axillary-dissection-after-neoadjuvant-chemotherapy-for-highly-selective-patients-with-initial-cn1-breast-cancer-a-single-center-prospective-trial
#19
JOURNAL ARTICLE
Xiuchun Chen, Zhenduo Lu, Chengzheng Wang, Minhao Lyu, Jianghua Qiao, Xianfu Sun, Lianfang Li, Chongjian Zhang, Zhenzhen Liu
BACKGROUND: Sentinel lymph node (SLN) biopsy is gradually accepted as the standard of care in breast cancer patients with down-staged axillary disease after neoadjuvant chemotherapy (NAC). However, it is still difficult to precisely define pre-NAC clinical node-positive (cN1) and post-NAC clinical node-negative (ycN0). This prospective single-center trial was designed to evaluate the feasibility and accuracy of standard targeted axillary dissection (TAD) after NAC in highly selective pre-NAC cN1 patients (not considering ultrasound-based axillary ycN staging)...
April 1, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38557589/efficacy-and-safety-of-bilastine-vs-levocetirizine-for-the-treatment-of-chronic-idiopathic-urticaria-a-multicenter-double-blind-double-dummy-phase-iii-non-inferiority-randomized-clinical-trial
#20
JOURNAL ARTICLE
Xue Chen, Xiuping Han, Bo Cheng, Hui Li, Lingling Liu, Songmei Geng, Linfeng Li, Jie Li, Qing Guo, Guoyi Zhang, Hong Fang, Jianzhong Zhang
No abstract text is available yet for this article.
April 1, 2024: Chinese Medical Journal
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