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Revista da Sociedade Brasileira de Medicina Tropical

Gabriel Pacífico Seabra Nunes, Patrícia da Silva Cunha, Daniele Patrícia Dal Bosco, Sandra Lúcia Euzébio Ribeiro
Hepatitis B infection is a global health issue. When considering patients with rheumatic diseases, this is no different. By using immunosuppressant drugs, such as DMARDs and biologics, viral reactivation is possible, leading to serious consequences on the patient. We report 3 cases of association between ankylosing spondylitis and hepatitis B with the use of immunosuppressant drugs. Case 1 was a patient with previous HBV infection using DMARD. Cases 2 and 3 were patients chronically infected by HBV during immunosuppressant therapy...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Mariane Albuquerque Lima Ribeiro, Gabriela Vieira de Souza Castro, Janis Lunier de Souza, Acigelda da Silva Cardoso, Fernanda Portela Madeira, Luis Marcelo Aranha Camargo, Dionatas Ulises de Oliveira Meneguetti
INTRODUCTION: This communication reports the first occurrence of Panstrongylus lignarius in the State of Acre, Brazil. METHODS: A specimen of P. lignarius was collected from a residence in a rural area of the municipality of Rio Branco, Acre, Western Amazon. RESULTS: This new report of P. lignarius extends the distribution of this species to eight Brazilian states, and also increases the number of species of Triatominae described from the state of Acre from nine to ten...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Gardenia de Oliveira Santos, Nathalia Priscila Sales de Jesus, Juliana Vasconcelos Cerqueira-Braz, Victor Santana Santos, Ligia Mara Dolce de Lemos
INTRODUCTION: Cases of visceral leishmaniasis (VL) and HIV co-infection have increased worldwide. We investigated the prevalence of HIV and associated factors among VL patients in Sergipe state, Brazil. METHODS: We conducted a population-based study of all cases of VL and HIV reported in Sergipe from 1999 to 2015. RESULTS: We studied a total of 917 patients; 41 (4.5%) co-infection cases were detected. VL-HIV co-infected patients were more likely to have weight loss, cough, treatment failure or loss to follow-up and death...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Ageane Mota da Silva, Jacqueline Sachett, Wuelton Marcelo Monteiro, Paulo Sérgio Bernarde
INTRODUCTION: We present here the risk from snakebites because of palm extractivism in western Amazonia. METHODS: The data were extracted from a cross-sectional sample study, from January 2016 to April 2018, at the Juruá Regional Hospital of Cruzeiro do Sul (Acre). RESULTS: There were 14 Bothrops incidents involving males, most of them occurring during the harvesting of "açaí" (Euterpe precatoria). CONCLUSIONS: During the harvesting of "açaí," there is the risk of the presence of B...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Simone Miyada, Artenio Jose Isper Garbin, Bruno Wakayama, Tania Adas Saliba, Clea Adas Saliba Garbin
INTRODUCTION: This study assessed the quality of life (QoL) of people with HIV/AIDS. METHODS: This cross-sectional epidemiological study was conducted at a specialized HIV/AIDS health facility of the Brazilian Public Health Service. Data were collected using the HIV/AIDS-Targeted Quality of Life (HAT-QoL) instrument. RESULTS: The study included 109 participants. Among the many significant statistical associations found in the study, the variables that had a greater effect on the domains assessed by the instrument were educational level, occupation, financial situation, ethnicity, and symptomatology...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Natalia Dos Santos Cavalcante, Heverton Rodrigo Reis de Lima, Denise Ferreira Tabosa, Elisa do Socorro Sousa Barbosa, Nayara Priscila da Silva Costa, Luana Mota da Costa, Paula Cristina Rodrigues Frade, Luisa Caricio Martins, Gláucia Caroline Silva-Oliveira, Aldemir Branco de Oliveira-Filho
INTRODUCTION: Female sex workers (FSWs) are considered a bridge for transmission of pathogens from high-risk to general populations. We assessed the epidemiological status of syphilis in FSWs along the Pará highway system. METHODS: Two hundred and twenty-two FSWs were interviewed and samples were analyzed using rapid qualitative tests and real-time polymerase chain reaction. RESULTS: The prevalence of syphilis was high (36.94%). The high rate of prostitution, use of illicit drugs, and search for financial resources increased Treponema pallidum transmission through unprotected sex...
March 18, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Cristiano José Mendes Pinto, Everton Henrique Ramos Pereira, Camila Machado Teodoro, Rute Angelica Becari, Viviane Gomes de Assis, Josiane Cristina Ferrari, Eduardo Luiz Hoehne
INTRODUCTION: Immunization is the primary method of preventing influenza. The objective of this study was to describe reasons and determine causes of acceptance or refusal of the influenza vaccine by elderly people. METHODS: This cross-sectional and descriptive study included elderly patients (aged >60 years) from the City of Jundiai, São Paulo, Brazil. RESULTS: The sample comprised 185 people; 71.9% reported receiving the vaccine and 21% claimed to have experienced complications...
March 14, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Renata Soares Martins, Michele Higa Fróes, Leila Del Castillo Saad, Satiro Márcio Ignácio Junior, Walkiria Delnero Almeida Prado, Ernesto Machado Figueiredo, Renato Pereira de Souza, Juliana Silva Nogueira, Adriana Yurika Maeda, Helena Keico Sato, Regiane Cardoso de Paula, Gizelda Katz
INTRODUCTION: The state of São Paulo has been monitoring cases of microcephaly and pregnant women presenting with acute rash, through CeVeSP. METHODS: This was a descriptive study focusing on pregnant women with rash and the outcome of their pregnancy, based on the notifications through the CeVeSP. RESULTS: During 2016, 2,209 cases of pregnant women with rash were reported and investigated. Of these, 36.6% were confirmed. Of the pregnant women who tested positive for ZIKV, 6...
March 14, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Ling Fei Tee, Toh Leong Tan, Hui-Min Neoh, Rahman Jamal
INTRODUCTION: The nematode Caenorhabditis elegans was used as a biological sensor to detect the urine of sepsis patients (CESDA assay). METHODS: C. elegans was aliquoted onto the center of assay plates and allowed to migrate towards sepsis (T) or control (C) urine samples spotted on the same plate. The number of worms found in either (T) or (C) was scored at 10-minute intervals over a 60-minute period. RESULTS: The worms were able to identify the urine (<48 hours) of sepsis patients rapidly within 20 minutes (AUROC=0...
March 14, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Pedro Luiz Tauil, João Barberino Santos, Cleudson de Castro Nery
No abstract text is available yet for this article.
March 14, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Matheus Tozatto Baptista Coelho Leal, Livia Silva Araújo Passos, Felipe Vieira Guarçoni, João Marcelo de Souza Aguiar, Rafael Benjamim Rosa da Silva, Thiago Mendonça Nunes de Paula, Rafael Figueiredo Dos Santos, Maria Cecília Landim Nassif, Nayana F A Gomes, Timothy C Tan, Maria Carmo Pereira Nunes
Rheumatic heart disease (RHD) remains a major cause of preventable death and disability in children and young adults. Despite significant advances in medical technology and increased understanding of disease mechanisms, RHD continues to be a serious public health problem throughout the world, especially in low- and middle-income countries. Echocardiographic screening has played a key role in improving the accuracy of diagnosing RHD and has highlighted the disease burden. Most affected patients present with severe valve disease and limited access to life-saving cardiac surgery or percutaneous valve intervention, contributing to increased mortality and other complications...
March 14, 2019: Revista da Sociedade Brasileira de Medicina Tropical
(no author information available yet)
[This corrects the article doi: 10.1590/0037-8682-0289-2018].
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Djane Clarys Baia-da-Silva, José Diego Brito-Sousa, Sheila Rodrigues Rodovalho, Cassio Peterka, Gilberto Moresco, Oscar Martín Mesones Lapouble, Gisely Cardoso de Melo, Vanderson de Souza Sampaio, Maria das Graças Costa Alecrim, Paulo Pimenta, José Bento Pereira Lima, Marcus Vinícius Guimarães de Lacerda, Wuelton Marcelo Monteiro
In Brazil, malaria is an important public health problem first reported in 1560. Historically, fluctuations in malaria cases in Brazil are attributed to waves of economic development; construction of railroads, highways, and hydroelectric dams; and population displacement and land occupation policies. Vector control measures have been widely used with an important role in reducing malaria cases. In this review article, we reviewed the vector control measures established in the Brazilian territory and aspects associated with such measures for malaria...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Vanessa Costa Dos Santos, Maria Isabel Schinoni, Isabela Silva de Oliveira, Maria Luiza Sousa Atta, Ajax Mercês Atta
INTRODUCTION: IgG subclasses involved in the immune response to hepatitis C virus (HCV) antigens have been rarely studied. We investigated the immune response mediated by IgG1 and IgG4 antibodies against the recombinant core and NS3 antigens in patients with chronic hepatitis C. METHODS: Sixty patients infected with HCV genotype 1 without antiviral treatment and 60 healthy subjects participated in the study. Serum levels of alanine aminotransferase, HCV viremia, and the presence of cryoglobulinemia and liver fibrosis were determined...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
André Tetzl Costa, Edelberto Santos Dias, Andreza Geisiane Maia Souza, Fabiana de Oliveira Lara E Silva, George Luiz Lins Machado-Coelho
INTRODUCTION: Leishmaniasis is a complex vector-borne infectious diseases caused by protozoan parasites in the genus Leishmania and spread by hematophagous phlebotomine sand flies (Diptera: Psychodidae, Phlebotominae). The aim of this study was to investigate the phlebotomine fauna, endophily and exophily of the species found, and possible influence of climatic factors on their populations. METHODS: The study was conducted in the Xakriabá Indigenous Reserve (XIR) in the municipality of São João das Missões in northern Minas Gerais state, Brazil...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Volmir Pitt Benedetti, Daiani Cristina Savi, Rodrigo Aluizio, Douglas Adamoski, Vanessa Kava, Lygia Vitória Galli-Terasawa, Chirlei Glienke
INTRODUCTION: Candidiasis is the most frequent opportunistic mycosis in humans and can cause mortality, particularly in immunodeficient patients. One major concern is the increasing number of infections caused by drug-resistant Candidas trains, as these cannot be efficiently treated with standard therapeutics. The most common mechanism of fluconazole resistance in Candida is mutation of ERG11, a gene involved in the biosynthesis of ergosterol, a compound essential for cell integrity and membrane function...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Danielle Guedes Dantas Lira, Danielly Cantarelli de Oliveira, Fábio André Brayner, André de Lima Aires, Mônica Camelo Pessoa A Albuquerque, Leucio Duarte Vieira, Célia Maria Machado Barbosa de Castro, Ana Durce Paixão
INTRODUCTION: The levels of the full-length form of the (pro)renin receptor (PRR), a component of the renin-angiotensin system (RAS), may be reduced in the membranes of kidneys in renal diseases. This study aimed to investigate the RAS components in the kidneys of mice submitted to a combination of a high-fat diet and Schistosoma mansoni infection. METHODS: Female BALB/c mice were maintained on a control or high-fat diet from 3 weeks of age. After 10 weeks on the designated diets, half the mice in each group were infected with S...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Fernando de Barros, João Carlos de Almeida Soares, Fernando Prado de Barros, Luiz Henrique Conde Sangenis, Gilberto Marcelo Sperandio da Silva, Ana Beatriz Monteiro Fonseca, Alejandro Marcel Hasslocher-Moreno, Andrea Silvestre de Sousa, Roberto Magalhães Saraiva, Mauro Felippe Felix Mediano
INTRODUCTION: The diagnosis and classification of megaesophagus can be challenging in patients with Chagas disease. The present study aimed to evaluate the agreement between upper endoscopies and esophagographies for the diagnosis and classification of megaesophagus in Chagas disease. METHODS: A cross-sectional study of 50 patients with Chagas disease with upper digestive symptoms was undertaken. Esophagography and upper endoscopy exams were performed to compare diagnoses...
March 7, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Tuane Carolina Ferreira Moura, Ednelza da Silva Graça Amoras, Maria Alice Freitas Queiroz, Simone Regina Souza da Silva Conde, Alan Barroso Araújo Grisólia, Ricardo Ishak, Antonio Carlos Rosário Vallinoto
INTRODUCTION: The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. METHODS: The study analyzed 185 blood samples obtained from patients with hepatitis B (n=74) and hepatitis C (n=111) and 300 samples from healthy donors. Genotyping was performed by real-time polymerase chain reaction, and protein levels were quantified using the automated immunoturbidimetric method...
February 21, 2019: Revista da Sociedade Brasileira de Medicina Tropical
Juliana Lúcia Duarte, Fredi Alexander Diaz-Quijano, Antônio Carlos Batista, Leandro Luiz Giatti
INTRODUCTION: This study aimed to examine the impact of climate variability on the incidence of dengue fever in the city of Rio Branco, Brazil. METHODS: The association between the monthly incidence of dengue fever and climate variables such as precipitation, temperature, humidity, and the Acre River level was evaluated, using generalized autoregressive moving average models with negative binomial distribution. Multiple no-lag, 1-month lag, and 2-month lag models were tested...
February 21, 2019: Revista da Sociedade Brasileira de Medicina Tropical
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