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Audrey E Evans
No abstract text is available yet for this article.
December 2003: Medical and Pediatric Oncology
#22
JOURNAL ARTICLE
Peter B Hesseling, Robin Broadhead, Elizabeth Molyneux, Eric Borgstein, Johann W Schneider, Mercia Louw, Erna P G Mansvelt, Glynn Wessels
BACKGROUND: Burkitt lymphoma (BL) accounts for 50% of childhood cancer in Malawi. Lack of resources precludes the use of new successful treatment approaches such as the LMB 89 group B protocol, which cures >80% of children with stage III BL with high dose chemotherapy and matching supportive care. Our objective was to achieve a good cure rate in Murphy stage I-III BL with manageable toxicity in Malawi at a drug cost of <1000 US dollars per patient. PROCEDURE: The intensity and toxicity of the LMB 89 group B protocol was reduced and adapted to Malawi realities...
December 2003: Medical and Pediatric Oncology
#23
JOURNAL ARTICLE
Bruce Shiramizu, Paul Mick
BACKGROUND: Hypermethylation of CpG islands in the promoter region of death-associated protein kinase (DAP-kinase) coupled with the loss of gamma-interferon-induced apoptosis have been reported in B-cell malignancies suggesting a role in pathogenesis or prognosis. Along with B-cell malignancies, pediatric lymphomas also include T-cell non-Hodgkin lymphoma (NHL), anaplastic large cell lymphoma, and Hodgkin disease, each with unique prognoses. The purpose of this study was to elucidate epigenetic changes in the DAP-kinase promoter region of pediatric cases to determine associations with aberrant hypermethylation...
December 2003: Medical and Pediatric Oncology
#24
COMPARATIVE STUDY
Benjamin Gesundheit, Giannoula Klement, Christof Senger, Robert Kerbel, Mark Kieran, Sylvain Baruchel, Laurence Becker
BACKGROUND: The clinical manifestations of childhood pilocytic astrocytoma (PA) and anaplastic astrocytoma (AA) markedly differ, especially in the time to progression and prognosis. Because of the aggressive course and poor survival rate of AA, one would expect it to be associated with a high angiogenic index. Counterintuitively, we often find higher microvessel density counts in PA than in AA. PROCEDURE: We examined the differences in type or density of microvasculature between the two neoplasms...
December 2003: Medical and Pediatric Oncology
#25
JOURNAL ARTICLE
Brian H Kushner, Kim Kramer, Michael P LaQuaglia, Shakeel Modak, Nai-Kong V Cheung
BACKGROUND: We reviewed the utility of different treatment modalities in a large series of adolescents/adults with neuroblastoma (NB). PROCEDURE: The 30 adolescents/adults (median age, 19 years) had stage 2B (n = 1), 3 (n = 2), or 4 (n = 27) NB. Treatments included conventional and myeloablative therapy; local radiotherapy (RT); immunotherapy with anti-G(D2) 3F8 monoclonal antibody +/- granulocyte-macrophage colony-stimulating factor (GM-CSF); and 3F8 alternating with low-dose oral etoposide...
December 2003: Medical and Pediatric Oncology
#26
JOURNAL ARTICLE
Kenneth L McClain, Purnima Laud, Wen-Shu Wu, Marilyn S Pollack
BACKGROUND: Current theory on the etiology of Langerhans cell histiocytosis (LCH), formerly Histiocytosis-X, is that abnormality(ies) of the immune system are responsible for dysregulation of Langerhans cells (LC) in patients' lesions. Among the known abnormalities in LCH patients are increased amounts of tumor necrosis factor alpha (TNF-alpha) and other cytokines in the lesions. PROCEDURE: We investigated the human leukocyte antigen (HLA) phenotypes of 29 patients and 37 healthy family members to determine if any haplotypes segregate with the presence or locations of the disease...
December 2003: Medical and Pediatric Oncology
#27
JOURNAL ARTICLE
Francesco Cetta, Luca Mazzarella, Giuseppina Bon, Michele Zuckermann, Alberto Casorelli, Hervé Nounga
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#28
LETTER
N Haider, M Mc Dermott, R J Fitzgerald
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#29
LETTER
Kathryn J Klopfenstein, Robin Rosselet, Amanda Termuhlen, Dwight Powell
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#30
LETTER
Renee V Gardner, Raj P Warrier, William Loe, Kenneth Ward, Marie Haymon, Randall Craver
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#31
LETTER
Sven Gottschling, Harald Reinhard, Sascha Meyer, Thomas Krenn, Norbert Graf, Martin Strowitzki
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#32
JOURNAL ARTICLE
Guillermo Chantada, Sandra Casak, Daniel Alderete, Pedro Zubizarreta, Guillermo Gallo, Federico Sackmann Muriel
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#33
JOURNAL ARTICLE
Moh'd El-Hayek, Omar Trad, Mikael Donner, Denis Hardy
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#34
COMPARATIVE STUDY
Andrew Shannon, James Smith, Kim Nagel, Roger Levesque, Theodore Warkentin, Ronald Barr
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#35
JOURNAL ARTICLE
Rajaram Nagarajan, Brenda J Weigel, Roby C Thompson, John P Perentesis
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#36
JOURNAL ARTICLE
P Schippel, I Lotz, K Rothe, C Greiner, C Mauz-Körholz
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#37
JOURNAL ARTICLE
Antonio Gonçalves de Oliveira-Filho, Marcio Lopes Miranda, Fabíola Leonelli Diz, Ruy Moraes Machado Guimarães, Simone Santos Aguiar, Joaquim Murray Bustorff-Silva
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#38
JOURNAL ARTICLE
Helmut Prosch, Andreas Feldges, Nicole Grois, Christian Fretz, Peter Spieler, Milen Minkov, Helmut Gadner
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#39
JOURNAL ARTICLE
Chetna Bakshi, Shripad Banavali, Nilesh Lokeshwar, Rajendra Prasad, Suresh Advani
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
#40
JOURNAL ARTICLE
Takashi Miyagi, Akitoshi Nagasaki, Tetsuro Nakazato, Nobuyuki Hyakuna, Nobuyuki Takasu, Masato Masuda
No abstract text is available yet for this article.
November 2003: Medical and Pediatric Oncology
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