Rene L Utianski, Gabriela Meade, Joseph R Duffy, Heather M Clark, Hugo Botha, Mary M Machulda, Dennis W Dickson, Jennifer L Whitwell, Keith A Josephs
Most recent studies of progressive apraxia of speech (PAOS) have focused on patients with phonetic or prosodic predominant PAOS to understand the implications of the presenting clinical phenotype. Patients without a clearly predominating speech quality, or mixed AOS, have been excluded. Given the implications for disease progression, it is important to understand these patients early in the disease course to inform appropriate education and prognostication. The aim of this study was to describe a cohort of ten patients with initially mixed PAOS and how their clinical course evolves...
August 20, 2023: Brain and Language