journal
https://read.qxmd.com/read/38466491/ecmm-center-of-excellence-a-shared-vision-for-the-diagnosis-and-treatment-of-fungal-infections
#21
EDITORIAL
Martin Hoenigl, Cornelia Lass-Flörl, Jean-Pierre Gangneux, Vishnu Chaturvedi
No abstract text is available yet for this article.
March 11, 2024: Mycopathologia
https://read.qxmd.com/read/38466469/the-cologne-ecmm-excellence-center-a-two-year-analysis-of-external-consultation-service-for-invasive-fungal-infections
#22
JOURNAL ARTICLE
Jon Salmanton-García, Philipp Koehler, Jan-Hendrik Grothe, Sibylle C Mellinghoff, Ertan Sal, Michaela Simon, Jannik Stemler, Oliver A Cornely, Rosanne Sprute
The European Confederation of Medical Mycology (ECMM), formed due to the surge in invasive fungal infections (IFI), initiated the Excellence Centers program in 2016 to guide stakeholders to leading medical mycology sites. This report focuses on the Cologne ECMM Excellence Center, recognized with Diamond status for active global involvement in 2017. The center offers free consultation via email and phone, responding within 24 h for life-threatening IFI, collecting data on origin, pathogens, infection details, and more...
March 11, 2024: Mycopathologia
https://read.qxmd.com/read/38407762/polymorphisms-in-innate-and-adaptive-immune-genes-in-subjects-with-allergic-bronchopulmonary-aspergillosis-complicating-asthma
#23
JOURNAL ARTICLE
Rimjhim Kanaujia, Amit Arora, Arunaloke Chakrabarti, Shivaprakash M Rudramurthy, Ritesh Agarwal
Innate and adaptive immunity play a crucial role in allergic bronchopulmonary aspergillosis (ABPA) pathogenesis. We performed next-generation sequencing using the Illumina TruSight One panel (4,811 human disease-associated genes, at least 20 × coverage) and selected 22 known immune genes (toll-like receptors (TLRs), C-type lectin, interleukin-4 receptor, and others). We included ABPA (n = 18), asthma without ABPA (n = 12), and healthy controls (n = 8)...
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407760/imported-case-of-disseminated-blastomycosis-in-india
#24
JOURNAL ARTICLE
Sudesh Gourav, Saurav Sekhar Paul, Gagandeep Singh, Manish Soneja, Immaculata Xess, Himanshu Mishra, Bhaskar Rana, Sonakshi Gupta, Mragnayani Pandey
No abstract text is available yet for this article.
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407729/fungal-colonization-of-the-airways-of-patients-with-cystic-fibrosis-the-role-of-the-environmental-reservoirs
#25
REVIEW
Ravenel Kévin, Guegan Hélène, Gastebois Amandine, Bouchara Jean-Philippe, Gangneux Jean-Pierre, Giraud Sandrine
Filamentous fungi frequently colonize the airways of patients with cystic fibrosis and may cause severe diseases, such as the allergic bronchopulmonary aspergillosis. The most common filamentous fungi capable to chronically colonize the respiratory tract of the patients are Aspergillus fumigatus and Scedosporium species. Defining the treatment strategy may be challenging, the number of available drugs being limited and some of the causative agents being multiresistant microorganisms. The knowledge of the fungal niches in the outdoor and indoor environment is needed for understanding the origin of the contamination of the patients...
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407673/circulatory-inflammatory-proteins-as-early-diagnostic-biomarkers-for-invasive-aspergillosis-in-patients-with-hematologic-malignancies-an-exploratory-study
#26
JOURNAL ARTICLE
Robina Aerts, Isis Ricaño-Ponce, Mariolina Bruno, Toine Mercier, Diletta Rosati, Johan Maertens, Vinod Kumar, Agostinho Carvalho, Mihai G Netea, Martin Hoenigl
OBJECTIVES: Invasive aspergillosis (IA) is a major cause of mortality in immunocompromised patients and it is difficult to diagnose because of the lack of reliable highly sensitive diagnostics. We aimed to identify circulating immunological markers that could be useful for an early diagnosis of IA. METHODS: We collected longitudinally serum samples from 33 cases with probable/proven IA and two matched control cohorts without IA (one with microbiological and clinical evidence of bacterial or viral non-fungal pneumonia and one without evidence of infection, all matched for neutropenia, primary underlying disease, and receipt of corticosteroids/other immunosuppressants) at a tertiary university hospital...
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407662/isolated-cutaneous-granuloma-caused-by-candida-parapsilosis-case-report-and-literature-review
#27
JOURNAL ARTICLE
Xinyu Yang, Xingji Jin, Zhusheng Yang, Youxue Wang, Aihua Wei, Xiumin Yang
Candidal granuloma is an uncommon type of deep chronic cutaneous candidiasis. Candida albican is the most common causative pathogen for candidal granuloma. We report herein the original case of a 69-year-old Chinese woman presented with a 3-year of painful cutaneous lesion on the back of left hand. Physical examination revealed a 4 × 5 cm large infiltrative reddish plaque with unclear boundaries. The yellow-white crusts were observed on the uneven surface of plaque. Histopathological examination of biopsy tissue revealed that yeast cells and the horizontal section of hyphae in the dermis by hematoxylin eosin staining and periodic acid-Schiff staining...
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407660/cutaneous-phaeohyphomycosis-of-caused-by-microsphaeropsis-arundini
#28
JOURNAL ARTICLE
Rifeng Chen, Dongyan Zheng, Xiuying Li, Cunwei Cao, Jiaguang Su
No abstract text is available yet for this article.
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38407639/eumycetoma-with-atypical-manifestation-caused-by-fusarium-first-case-diagnosed-by-pcr-and-next-generation-sequencing-in-china
#29
JOURNAL ARTICLE
Xiao Liu, Ruoyu Li, Yinggai Song, Aiping Wang
No abstract text is available yet for this article.
February 26, 2024: Mycopathologia
https://read.qxmd.com/read/38372905/fatal-fulminant-histoplasmosis-diagnosed-by-cytopathology
#30
JOURNAL ARTICLE
Nao Hara, Tasleem Banu, Sayed Shahabuddin Hoseini, Thomas Pustorino, Ljiljana Vasovic, Liying Han, Marina Keller, Vishnu Chaturvedi
No abstract text is available yet for this article.
February 19, 2024: Mycopathologia
https://read.qxmd.com/read/38324097/anti-candida-antibodies-of-patients-with-invasive-candidiasis-inhibit-growth-alter-cell-wall-structure-and-kill-candida-albicans-in-vitro
#31
JOURNAL ARTICLE
Giulia Carrano, Inés Arrieta-Aguirre, Ander Díez, Marta Bregón-Villahoz, Iñigo Fernandez-de-Larrinoa, María-Dolores Moragues
Invasive candidiasis (IC), caused by Candida yeasts, particularly Candida albicans, poses a significant threat with high mortality rates. Diagnosis is challenging due to Candida's common presence in human microbiota. To address this, our research group developed an immunofluorescence assay detecting Candida albicans Germ Tube Antibodies (CAGTA) in IC patients. CAGTA, indicative of invasive processes, is associated with a lower mortality rate in ICU patients. Based on this premise, this study aims to provide results regarding the lack of knowledge about the potential activity of CAGTA against invasive infections in humans caused by the fungus Candida albicans...
February 7, 2024: Mycopathologia
https://read.qxmd.com/read/38265566/expression-profiles-of-protease-in-onychomycosis-related-pathogenic-trichophyton-rubrum-and-tinea-capitis-related-pathogenic-trichophyton-violaceum
#32
JOURNAL ARTICLE
Jingjing Chen, Yangmin Gao, Shuzhen Xiong, Zimei Peng, Ping Zhan
The two fungal species Trichophyton rubrum and Trichophyton violaceum are common pathogens on human, infecting keratinized tissue of the outer body parts. Both species are belonging to the "Trichophyton rubrum complex" and share very high similarity in the genome. Secreted proteinases, key factors for keratin degradation, are nearly identical. Contrary, the ecological niches are differing. Trichophyton rubrum preferably infects skin and nails, whereas T. violaceum preferably infects the scalp. We postulate, that differences in the protease expression contribute to differences in ecological preferences...
January 24, 2024: Mycopathologia
https://read.qxmd.com/read/38265528/multicentric-study-on-the-clinical-mycology-capacity-and-access-to-antifungal-treatment-in-portugal
#33
JOURNAL ARTICLE
Raquel Fernandes, Raquel Sabino, Cristina Cunha, Oliver A Cornely, Agostinho Carvalho, Jon Salmanton-García
The success of the clinical management of invasive fungal diseases (IFD) is highly dependent on suitable tools for timely and accurate diagnosis for effective treatment. An in-depth analysis of the ability of European institutions to promptly and accurately diagnose IFD was previously conducted to identify limitations and aspects to improve. Here, we evaluated and discussed the specific case of Portugal, for which, to our knowledge, there are no reports describing the national mycological diagnostic capacity and access to antifungal treatment...
January 24, 2024: Mycopathologia
https://read.qxmd.com/read/38252180/eczematoid-cutaneous-fusariosis-in-a-7-year-old-boy
#34
JOURNAL ARTICLE
Yubo Ma, Ruoyu Li, Zhe Wan, Xiaowen Wang, Aiping Wang
No abstract text is available yet for this article.
January 22, 2024: Mycopathologia
https://read.qxmd.com/read/38231463/onychomycosis-of-hand-and-foot-due-to-acremonium-egyptiacum
#35
JOURNAL ARTICLE
Rodrigo Cruz Choappa, Peggy Vieille Oyarzo, Melisa Noguera Gahona, Massimo Cogliati
No abstract text is available yet for this article.
January 17, 2024: Mycopathologia
https://read.qxmd.com/read/38231458/observation-of-a-bone-invasion-model-of-aspergillus-fumigatus-in-vitro-and-analysis-of-the-antifungal-susceptibility
#36
JOURNAL ARTICLE
Yan Shao, Min Shen, Dan Peng, Wenxu Cheng, Chenggang Mao, Heng Zhang, Yi Sun
BACKGROUND: Recently, the prevalence of invasive fungal infections has been on the rise, and one of the prevalent symptoms frequently observed is bone deterioration and bone loss. MATERIALS AND METHODS: Using an in vitro model we studied how Aspergillus fumigatus invades the bone. Pathological analysis was then employed to observe the structure and distinctive features of the invading fungal elements within the bone invasion model. Meanwhile, the antifungal effects of itraconazole, voriconazole, posaconazole, and amphotericin B were evaluated...
January 17, 2024: Mycopathologia
https://read.qxmd.com/read/38231420/trends-in-the-incidence-of-disseminated-cryptococcosis-in-japan-a-nationwide-observational-study-2015-2021
#37
JOURNAL ARTICLE
Hidemasa Akazawa, Hideharu Hagiya, Toshihiro Koyama, Fumio Otsuka
BACKGROUND: Cryptococcus species can cause severe disseminated infections in immunocompromised hosts. This study investigated the epidemiological features and trends in disseminated cryptococcosis in Japan. METHODS: We used publicly available Infectious Diseases Weekly Reports to obtain data on the incidence of disseminated cryptococcosis in Japan from 2015 to 2021. Patient information, including age, sex, and regional and seasonal data, were extracted. The Joinpoint regression program was used to determine the age-adjusted incidence rate (AAR) per 100,000 population, annual percentage change (APC), and average APC (AAPC)...
January 17, 2024: Mycopathologia
https://read.qxmd.com/read/38231407/mixed-aspergillosis-and-mucormycosis-infections-in-patients-with-covid-19-case-series-and-literature-review
#38
REVIEW
Elahe Sasani, Farzad Pakdel, Sadegh Khodavaisy, Mohammadreza Salehi, Amir Salami, Marjan Sohrabi, Pouyan Aminishakiba, Iman Amirafzali, Arezoo Salami Khaneshan
BACKGROUND: Mucormycosis and aspergillosis are angioinvasive infections mainly occurring in immunocompromised patients. However, mixed infection with mucormycosis and aspergillosis in post-COVID-19 patients is rare. In this report, we will report four cases and comprehensively review the published literature on COVID-19 associated mixed infection of aspergillosis and mucormycosis. METHOD: Besides four of our cases, we searched for published articles using PubMed/MEDLINE, Scopus, and Web of Science databases from the beginning of 2020 until October 2023...
January 17, 2024: Mycopathologia
https://read.qxmd.com/read/38231396/subcutaneous-hyalohyphomycosis-caused-by-scedosporium-aurantiacum-treated-with-posacanazole
#39
JOURNAL ARTICLE
Kayo Kashiwada-Nakamura, Hiromitsu Noguchi, Takashi Yaguchi, Kazumi Urata, Shuichi Shimada, Soichiro Sawamura, Katsunari Makino, Ikko Kajihara, Katsumasa Ideo, Sara Higuchi, Satoshi Fukushima
No abstract text is available yet for this article.
January 17, 2024: Mycopathologia
https://read.qxmd.com/read/38231359/disseminated-basidiobolomycosis-caused-by-basidiobolus-omanensis-in-a-child-with-acute-lymphoblastic-leukemia-all-case-report-and-literature-review
#40
REVIEW
Laila Al Yazidi, Sharifa Al Sinani, Badriya Al Adawi, Marwa Al Riyami, Yasser Wali, Abdulhakeem Al Rawas, Buthaina Al Musalhi, Jacques F Meis, Saif Al Housni, Ahmed Al-Harrasi, Abdullah M S Al Hatmi
Basidiobolomycosis is an uncommon fungal infection caused by the genus Basidiobolus. In immunocompetent children, it usually causes cutaneous infection and rarely affects the gastrointestinal tract, and it is extremely rare for the disease to spread. The present study reports the first case of disseminated basidiobolomycosis caused by Basidiobolus omanensis in a child with acute lymphoblastic leukemia who died as a result of uncontrolled infection and multi-organ failure despite surgical and antifungal therapy with L-AMB and voriconazole...
January 17, 2024: Mycopathologia
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