Matilda Xinwei Lee, Siyu Peng, Ainsley Ryan Yan Bin Lee, Shi Yin Wong, Ryan Yong Kiat Tay, Jiaqi Li, Areeba Tariq, Claire Xin Yi Goh, Ying Kiat Tan, Benjamin Kye Jyn Tan, Chong Boon Teo, Esther Chan, Melissa Ooi, Wee Joo Chng, Cheng Ean Chee, Carol L F Ho, Robert John Walsh, Maggie Wong, Yan Su, Lezhava Alexander, Sunil Kumar Sethi, Shaun Shi Yan Tan, Yiong Huak Chan, Kelvin Bryan Tan, Soo Chin Lee, Louis Yi Ann Chai, Raghav Sundar
INTRODUCTION: Three doses of SARS-CoV-2 mRNA vaccines have been recommended for cancer patients to reduce the risk of severe disease. Anti-neoplastic treatment, such as chemotherapy, may affect long-term vaccine immunogenicity. METHOD: Patients with solid or haematological cancer were recruited from 2 hospitals between July 2021 and March 2022. Humoral response was evaluated using GenScript cPASS surrogate virus neutralisation assays. Clinical outcomes were obtained from medical records and national mandatory-reporting databases...
January 2023: Annals of the Academy of Medicine, Singapore