journal
https://read.qxmd.com/read/38788046/tislelizumab-combined-with-gt-chemotherapy-for-intimal-sarcoma-of-inferior-vena-cava-a-case-report
#1
JOURNAL ARTICLE
Haihong Liao, Yong Fang, Da Li, Yuefen Pan, Zhongfeng Niu, Tianhong Fu, Zhuoxuan Wu, Jin Sheng, Yong Dong, Shuwen Han, Quan Qi, Yulong Liu
RATIONALE: Intimal sarcoma of inferior vena cava (IVC) is a rare soft tissue sarcoma with no typical symptoms and specific imaging features in the early stage, and there is a lack of standardized treatment and methods. PATIENT CONCERNS: A 54-year-old female patient presented to Fenghua District People's Hospital with a post-active cough and hemoptysis and was subsequently referred to our hospital. DIAGNOSES: The patient was pathologically diagnosed as intimal sarcoma of IVC complicating multiple intrapulmonary metastases...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788045/the-relationship-between-adipose-tissue-raas-activity-and-the-risk-factors-of-prediabetes-in-different-ethnicities-a-protocol-for-a-systematic-review-and-meta-analysis
#2
JOURNAL ARTICLE
Bongeka Cassandra Mkhize, Palesa Mosili, Nomusa Mzimela, Phikelelani Sethu Ngubane, Andile Khathi
BACKGROUND: The incidence and prevalence of prediabetes has become a global concern. The risk factors of prediabetes, such as insulin resistance, adiposity, lipotoxicity and obesity, in conjunction with the alteration of the renin-angiotensin-aldosterone system (RAAS), have been positively correlated with the high morbidity and mortality rate. Thus, this systematic review seeks to establish the relationship between the risk factors of prediabetes, namely insulin resistance adiposity, lipotoxicity, obesity and the RAAS...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788044/effects-of-effortful-swallowing-against-kinesiology-taping-resistance-on-the-swallowing-function-in-patients-with-poststroke-dysphagia-a-randomized-controlled-trial
#3
RANDOMIZED CONTROLLED TRIAL
Hwan-Hee Kim, Ji-Su Park
BACKGROUND: A dysphagia rehabilitation method using kinesiology taping (KT) was recently introduced, and its potential for clinical efficacy was demonstrated by evaluating muscle activity and thickness. However, its effect on the swallowing function in patients with dysphagia remains unclear. This study aimed to investigate the effects of effortful swallowing against KT resistance on the swallowing function in patients with post stroke dysphagia. METHODS: Thirty patients with poststroke dysphagia were recruited and randomly assigned to the experimental and placebo groups...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788043/a-meta-analysis-of-recombinant-human-endostatin-combined-with-np-regimen-for-treating-non-small-cell-lung-cancer
#4
JOURNAL ARTICLE
Chao Gao, Chaoqian Gao, Qin Yuan
BACKGROUND: The aim of this study was to evaluate the efficacy and safety of recombinant human endostatin in combination with vinorelbine + cisplatin (NPE) for the treatment of advanced non-small cell lung cancer (NSCLC). METHODS: Randomized controlled trials (RCTs) of NPE for advanced NSCLC in PubMed, Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure, and Wanfang databases were searched using a computerized search of the database from the time of creation to May 2023...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788042/evaluation-of-the-efficacy-and-safety-of-yukwool-tang-for-major-depressive-disorder-in-women-a-randomized-double-blinded-placebo-controlled-parallel-trial
#5
RANDOMIZED CONTROLLED TRIAL
Young Kyung Seo, Sunyoung Choi, Youngeun Choi, Sungmin Choi, Ojin Kwon, Hyungjun Kim, In Chul Jung
BACKGROUND: Major depressive disorder (MDD) occurs more often in women than that in men due to various complex causes. This study aimed to evaluate the effectiveness and safety of Yukwool-tang (YWT) for MDD in women. METHODS: A total of 72 patients diagnosed with MDD and Korean version of the Hamilton Depression Rating Scale (K-HDRS) ≥ 14 points were randomly assigned to the YWT or placebo group, and 1 bottle (30 mg) of No-S solution and placebo was administered to the YWT and placebo groups, respectively, orally thrice a day for 8 weeks...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788041/investigation-on-the-efficiency-of-lentinan-for-injection-combining-cisplatin-on-treating-malignant-pleural-effusion-based-on-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Yixuan Wang, Haojia Wang, Keyan Chai, Siyu Guo, Yifei Gao, Jiaqi Li, Chuanqi Qiao, Siyun Yang, Jiying Zhou, Yifan Lin, Xiaomeng Zhang, Jiarui Wu
BACKGROUND: Malignant pleural effusion (MPE) is a frequently observed complication in advanced malignant tumors. Clinical studies have shown that lentinan for injection (LNT) is beneficial for improving patients' quality of life and prolonging their survival. The purpose of this meta-analysis is to evaluate the efficacy and safety of LNT combining cisplatin in the treatment of MPE. METHODS: Randomized controlled trials (RCTs) of LNT combining cisplatin in the treatment of MPE were searched in 6 literature databases from the establishment time of each database by 2 researchers...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788040/development-and-trends-in-research-on-hypertension-and-atrial-fibrillation-a-bibliometric-analysis-from-2003-to-2022
#7
JOURNAL ARTICLE
Nan Tang, Qiang Zhou, Shuang Liu, Kangming Li, Zhen Liu, Qingdui Zhang, Huamei Sun, Cheng Peng, Ji Hao, Chunmei Qi
BACKGROUND: This study aimed to comprehensively analyze research related to hypertension and atrial fibrillation, 2 common cardiovascular diseases with significant global public health implications, using bibliometric methods from 2003 to 2022. METHODS: From the Web of Science Core Collection database, literature on the theme of hypertension and atrial fibrillation was retrieved. Subsequently, comprehensive bibliometric analyses were conducted across multiple dimensions utilizing software tools such as VOSviewer, Citespace, Pajek, Scimago Graphica, and ClusterProfiler...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788039/causal-relationship-between-gut-microbiota-and-intracranial-hemorrhage-a-two-sample-mendelian-randomization-study
#8
JOURNAL ARTICLE
Jiameng Jia, Lin Zhou, Nan Wang, Qiang Zheng
Patients with intracranial hemorrhage (ICH) usually have an imbalance in the gut microbiota (GM); however, whether this is a causal correlation remains unclear. This study used summary data from an open genome-wide association study to conduct double-sample Mendelian randomization (MR) to test the causal correlation between GM and ICH. First, we used a cutoff value of P < 10E-5 to select single nucleotide polymorphisms critical for each GM. Inverse variance weighted, weighted median, and MR-PRESSO methods were used to evaluate the strength of this causal association...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788038/association-of-admission-serum-triglyceride-levels-with-intensive-care-unit-hospitalization-rates-in-acute-pancreatitis-patients-a-retrospective-study
#9
JOURNAL ARTICLE
Shuaiyong Wen, Yu Zhang, Guijie Zhao, Zhengwei Tu, Kun Zhang, Yunfeng Cui
Acute pancreatitis (AP) is a complex and unpredictable condition, of which hypertriglyceridemia (HTG) is the third most prevalent cause. This study aimed to conduct a retrospective analysis of clinical data from hospitalized AP patients to uncover a potential correlation between triglyceride (TG) levels and the necessity for intensive care unit (ICU) admission. This retrospective cohort study utilized the Medical Information Mart for Intensive Care IV 2.2 (MIMIC-IV) critical care dataset, incorporating data from 698 patients with hypertriglyceridemic acute pancreatitis (HTG-AP)...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788037/molecular-mechanism-of-wedelolactone-inhibits-high-glucose-induced-human-retinal-vascular-endothelial-cells-injury-through-regulating-mir-190-expression
#10
JOURNAL ARTICLE
Xiaojie Cai, Xiao Wang, Yuping Huang, Xiaopang Rao
To investigate the effects and molecular mechanisms of wedelolactone (WEL) on high glucose-induced injury of human retinal vascular endothelial cells (HRECs). The cell injury model was established by incubating HRECs with 30 mmol/L glucose for 24 hour. HRECs were divided into control (Con) group, high glucose (HG) group, HG + WEL-low dose (L) group, HG + WEL-medium dose (M), HG + WEL-high dose (H) group, HG + miR-NC group, HG + miR-190 group, HG + WEL + antimiR-NC group, HG + WEL + antimiR-190 group...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788036/clinical-effect-of-perioperative-stellate-ganglion-block-on-mechanical-ventilation-and-respiratory-function-of-elderly-patients-with-septic-shock
#11
RANDOMIZED CONTROLLED TRIAL
Yingchuan Yuan, Lu Chen
BACKGROUND: Here we investigated the effect of a stellate ganglion block on the perioperative mechanical ventilation and postoperative recovery of respiratory function of elderly patients with infectious shock. METHODS: Thirty-six elderly patients with septic shock who underwent emergency general anesthesia at our hospital were randomly divided into treatment (T) and control (C) groups (n = 18 each). Group T received a preoperative stellate ganglion block, whereas group C received normal saline...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788035/unveiling-hotspots-and-trends-in-hip-arthroscopy-research-a-bibliometric-and-visualized-analysis-1900-2022
#12
JOURNAL ARTICLE
Jinlong Tian, Yanlei Li, Yu Tong, Lichen Ji, Wei Zhang, Xugang Zhong, Senbo Zhu, Yao Kang, Qing Bi
Over the past 10 years, hip arthroscopy has been increasingly employed to effectively diagnose and safely treat a range of hip pathologies. With research related to hip arthroscopy continually expanding, the number of articles connected with hip arthroscopy has also consistently grown. We aimed to investigate trends and hotspots in hip arthroscopy-related research, and analyze the top 100 most-cited articles on hip arthroscopy. We searched for ("hip arthroscopy") AND ("article" OR "review") AND "English" in the Web of Science database from 1900 to 2022, which was used to obtain all publications relating to hip arthroscopy...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788034/balance-performance-among-horseback-rider-compared-to-non-horseback-rider-women-in-saudi-arabia-a-cross-sectional-study
#13
JOURNAL ARTICLE
Alaa M Albishi
Horseback riding requires adapting to constant changes in balance conditions, maintaining equilibrium on the horse, and preventing falls. However, differences in balance performance among horseback riders and non-rider-healthy young women in Saudi Arabia have not been explored. This study investigates whether horseback-rider women would perform better on static and dynamic balance tests than non-rider women. Also, the study examined the effect of years of horseback riding on balance performance in the rider group...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788033/factors-associated-with-early-postoperative-mortality-after-total-anomalous-pulmonary-venous-connection-repair-a-retrospective-cohort-study
#14
JOURNAL ARTICLE
Ali Alakbar Nahle, Hussein Hamdar, Jameel Soqia, Mohamad Diab, Jamal Ataya, Alwaleed Al-Dairy
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital defect where pulmonary venous plexus fails to connect with the left atrium (LA). Surgical repair is the primary treatment for TAPVC, but factors influencing outcomes are not fully understood. This study investigates the early outcomes of surgical repair for TAPVC and associated factors. A retrospective cohort analysis was conducted on TAPVC patients who underwent surgical repair between 2012 and 2022. Data were collected from medical records and supplemented with phone call validation...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788032/a-case-report-of-thrombocytopenic-covid-19-and-miller-fisher-syndrome-on-a-concurrent-chronic-immune-neuropathy
#15
JOURNAL ARTICLE
Lisle Blackbourn, Umair Hamid, Janaki Tokala, Gregory Blume
RATIONALE: Miller-Fisher syndrome (MFS) is a rare subtype of Guillain-Barre syndrome with classic features of ataxia, areflexia, and ophthalmoplegia that can be caused by a preceding infection including COVID-19. We present a current, asymptomatic thrombocytopenic COVID-19 infection as a cause of MFS in a 60-year-old male with a concurrent chronic immune neuropathy. PATIENT CONCERNS: A 60-year-old male presenting with acute symptoms of MFS including ataxia, areflexia, and ophthalmoplegia on a chronic immune neuropathy for at least 1 year and concurrent asymptomatic COVID-19 positive infection...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788031/association-between-maternal-and-perinatal-outcomes-and-histological-changes-in-the-placenta-of-patients-with-covid-19-a-cohort-study
#16
JOURNAL ARTICLE
Luiza Rocha de Souza, Melania Maria Ramos Amorim, Alex Sandro Souza, Brena Carvalho Pinto de Melo, Christiane Tiné Cantilino, Maria Alice de Oliveira Saunders, Maria Jucá de Petribú, Luciana Soares Lúcio, Juliana Rodrigues Marinho, Maria Eduarda Virgínia de Oliveira Correia, Leila Katz
Although studies evaluated placental involvement in Covid-19 patients, few have assessed its association with clinical repercussions. The study aimed to determine the association between the clinical status and maternal and perinatal outcomes of patients with Covid-19 at delivery and changes in placental histology. It is so far the largest cohort evaluating placentas of patients infected by the SARS-CoV-2. A secondary analysis was conducted of a database from which a cohort of 226 patients, who tested real-time polymerase chain reaction-positive for Covid-19 at delivery and whose placentas were collected and submitted to pathology, was selected for inclusion...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788030/correlation-between-relative-dose-intensity-of-adjuvant-s-1-chemotherapy-and-psoas-muscle-mass-volume-and-survival-after-resection-of-pancreatic-ductal-adenocarcinoma-a-retrospective-study
#17
JOURNAL ARTICLE
Teruhisa Sakamoto, Mikiya Kishino, Yuki Murakami, Kozo Miyatani, Takehiko Hanaki, Yuji Shishido, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Yoshiyuki Fujiwara
This study aimed to investigate the prognostic relationship between relative dose intensity (RDI) of adjuvant S-1 chemotherapy and psoas muscle mass volume (PMV) in patients with resected pancreatic ductal adenocarcinoma. We enrolled 105 patients with histologically confirmed pancreatic ductal adenocarcinoma who had undergone pancreatectomy. Adjuvant S-1 chemotherapy was administered to 72 (68.6%) of the 105 patients and not to the remaining 33 patients. Patients who received adjuvant S-1 chemotherapy were stratified into high- and low-RDI groups by the cutoff value for RDI...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788029/clinical-inertia-in-thyrotropin-suppressive-therapy-for-low-risk-differentiated-thyroid-cancer-a-real-world-experience-at-an-endocrine-center-in-bangkok
#18
JOURNAL ARTICLE
Yotsapon Thewjitcharoen, Waralee Chatchomchuan, Ekgaluck Wanothayaroj, Siriwan Butadej, Soontaree Nakasatien, Sirinate Krittiyawong, Rajata Rajatanavin, Thep Himathongkam
The management of low-risk differentiated thyroid cancer (DTC) has evolved over time toward treatment de-escalation. However, overtreatment with supraphysiological dose of levothyroxine (LT4) continues to be observed despite current clinical guideline. This study aimed to assess the actual thyrotropin suppressive therapy for low-risk DTC patients at an endocrine center in Bangkok. This retrospective study included patients with low-risk DTC who were regularly follow-up for at least 18 months at Theptarin Hospital between 2016 and 2022...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788028/influence-of-exercise-prescription-intervention-based-on-wechat-on-glycolipid-metabolism-and-fitness-of-suboptimal-health-teachers
#19
RANDOMIZED CONTROLLED TRIAL
Yimei Duan, Shunchang Li, Quansheng Su, Simao Xu, Guotian Lu
Exercise is an effective means to promote health, but adherence is low. Due to the advantages of immediacy, economy and effectiveness, the use of WeChat social software has permeated into every aspect in daily life in China. To explore the influence of WeChat-based exercise prescription intervention mode on glycolipid metabolism and fitness of suboptimal-health teachers. 293 suboptimal-health teachers with senior professional titles were randomized to a control group (CG) or an experimental group (e.g.). The CG exercised on its own, while the e...
May 24, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38788027/therapeutic-options-for-different-metastatic-sites-arising-from-renal-cell-carcinoma-a-review
#20
REVIEW
Xue Wang, Lin Qian, Zengxing Qian, Qihang Wu, Dongying Cheng, Junjun Wei, Lingmin Song, Shuaihuai Huang, Xiaodong Chen, Ping Wang, Guobin Weng
Renal cell carcinoma (RCC) stands among the top 10 malignant neoplasms with the highest fatality rates. It exhibits pronounced heterogeneity and robust metastatic behavior. Patients with RCC may present with solitary or multiple metastatic lesions at various anatomical sites, and their prognoses are contingent upon the site of metastasis. When deliberating the optimal therapeutic approach for a patient, thorough evaluation of significant risk factors such as the feasibility of complete resection, the presence of oligometastases, and the patient's functional and physical condition is imperative...
May 24, 2024: Medicine (Baltimore)
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