journal
https://read.qxmd.com/read/38099609/evaluation-of-the-antiplatelet-effect-of-generic-ticagrelor-90-mg-ticaspan-%C3%A2-alone-and-in-combination-with-aspirin-75-mg-as-compared-to-ticagrelor-innovator-an-in-vitro-study
#21
JOURNAL ARTICLE
S Kamat, S Jalgaonkar, P Marathe, S Karekar, D Uchil, S Revankar
OBJECTIVE: To evaluate an in vitro antiplatelet effect of generic ticagrelor 90 mg (ticaspan) alone and in combination with aspirin 75 mg as compared to the innovator formulation of ticagrelor alone and in combination with aspirin among healthy Indian volunteers. METHODS: 18 volunteers were enrolled and platelet viability was tested using lactate dehydrogenase (LDH) assay in six of 18 volunteers. In 12 volunteers, maximum platelet aggregation (MPA) and percentage inhibition of platelet aggregation (PI) were assessed using a platelet aggregometer in six study groups...
December 7, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/38099610/complete-agenesis-of-dorsal-pancreas-a-rare-cause-of-insulin-dependent-diabetes-mellitus
#22
S Ray, K K Behera, T P Tripathy
We report a 16-year-old boy who presented with abdominal pain and severe hyperglycemia. His random blood glucose on admission was above 300 mg/dL, without ketosis. Urine examination revealed mild ketonuria. Renal function tests were normal. Antibodies to glutamate acid decarboxylase (anti-GAD) and islet tyrosine phosphatase 2 (anti-IA2) were negative. Findings on enhanced abdominal computed tomography scan were compatible with complete dorsal pancreatic agenesis. The body and tail of the pancreas were not visualized...
December 6, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/38037772/facial-nerve-communication-with-ansa-cervicalis-an-unusual-anatomical-variation
#23
S Gulati, S Tripathy, T Gupta, S Gaba
Neural connections of the seventh cranial nerve with its neighboring nerves are common and well documented; however, communication with ansa cervicalis is as yet unknown. We present a case with such a connection found during cadaveric dissection, with hitherto unknown consequences. In this specimen, after giving the marginal mandibular and cervical branches, the cervicofacial division continued distally to communicate with the distal loop of ansa cervicalis. Presence of such connection may result in facial muscle paralysis on injury to the ansa or strap muscle paralysis on injury to the facial nerve, depending on the direction of nerve fibers...
November 28, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/38037771/placental-pathology-cracks-in-the-feto-maternal-bridge
#24
JOURNAL ARTICLE
P Vaideeswar, P A Sathe
No abstract text is available yet for this article.
November 27, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/38037770/status-of-oral-anticoagulant-use-in-a-tertiary-center-in-south-india
#25
JOURNAL ARTICLE
S Gajbhiye
No abstract text is available yet for this article.
November 27, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37843151/chronic-thromboembolic-pulmonary-hypertension-time-is-of-the-essence
#26
EDITORIAL
V Taskar
No abstract text is available yet for this article.
October 16, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37787265/how-often-are-heart-diseases-correctly-diagnosed-antemortem-in-children-with-fatal-illnesses-a-retrospective-review-of-medical-and-autopsy-records
#27
JOURNAL ARTICLE
S Karande, P Vaideeswar, T More
This retrospective study analyzed the concordance level between clinical and autopsy diagnosis of heart diseases over six years. Utilizing the Goldmann classification, the concordance rate was found to be 38.1%. Major discrepancies (Class I and II) were found in 39% cases and minor (Class III and IV) in 22.9% cases.
September 29, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37787263/rete-middle-cerebral-artery-presenting-with-a-ruptured-aneurysm
#28
D K Singh, D Shankar, K Yadav, M Kaif
The developmental anomaly of the middle cerebral artery (MCA) is a rare occurrence. Rete MCA, also known as "unfused," "twig-like," and aplastic MCA, is an even rarer anomaly. These immature rete vessels are prone to flow-related aneurysms which rupture themselves presenting with intraparenchymal hematoma. We here with present a case of rete MCA with a ruptured aneurysm and discuss its pathophysiology and management.
September 29, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37706418/soft-syndrome-with-kohlschutter-tonz-syndrome
#29
S A Mondkar, V Khadilkar, P Kasegaonkar, A Khadilkar
We report a 2.2 year-old-boy, born of consanguineous marriage, referred for short stature, with history of neonatal death and skeletal deformities in his older sibling. Rhizo-mesomelic dwarfism was detected antenatally. Within 24 hours of birth, he developed multiple seizures. Examination revealed severe short stature, dolichocephaly, broad forehead, deep set eyes, low set ears, bulbous nose, small, irregular teeth, pointed chin, and triangular facies. He had rhizomelic shortening, stubby fingers, pes planus, and scanty hair...
September 7, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37675665/study-of-placental-histopathology-in-covid-19-mothers-at-a-dedicated-covid-19-hospital-in-india
#30
JOURNAL ARTICLE
S K Lad, K D Jashnani, M Pophalkar, B Jnanananda, N Mahajan
INTRODUCTION: Maternal infections can affect the placenta, which acts as a fetomaternal barrier. This study aimed to determine the spectrum of morphologic alterations in the placentas of pregnancies complicated by SARS-CoV-2 infection and the impact on fetal or neonatal outcomes. MATERIALS AND METHODS: This is a prospective case-control study. One hundred SARS-CoV-2 positive pregnant women and an equal number of SARS CoV-2 negative pregnant women in their third trimester who delivered at our tertiary care center between December 2020 and November 2021 were enrolled in the study...
September 5, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37555424/post-transplant-diarrhea-and-immunosuppressant-withdrawal-insights-and-limitations
#31
JOURNAL ARTICLE
M Kulkarni
No abstract text is available yet for this article.
August 4, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37555423/skull-base-temporal-encephalocele-hidden-cause-of-temporal-lobe-epilepsy
#32
JOURNAL ARTICLE
R Pillai, A Chheda, S Agrawal, S Ravat, S Sankhe, D Muzumdar
In the present study patients with previously diagnosed MRI-negative temporal lobe epilepsy (TLE) on long-term video electroencephalography (VEEG) monitoring were re-evaluated with high resolution 3T MRI brain to look out for a skull base temporal lobe encephalocoele (TE). A total of 234 VEEGs were analyzed. TLE had been diagnosed in 104 patients based on semiology, ictal, interictal EEG data, and brain positron emission tomography (PET) studies. Of these, 99 patients had temporal lobe abnormality (78 had mesial temporal sclerosis, 8 had tumor, 3 had focal cortical dysplasia, and 10 had mixed pathology)...
August 4, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37555422/ambulatory-blood-pressure-monitoring-in-pheochromocytoma-paraganglioma-a-single-center-experience
#33
JOURNAL ARTICLE
S S Memon, P Srivastava, M Karlekar, H Thakkar, T Bandgar
CONTEXT/AIMS: Pheochromocytoma and paraganglioma (PPGL) are rare tumors, and data on ambulatory blood pressure monitoring (ABPM) in these patients and the effect of blocking on ABPM parameters is limited. We aimed to describe ABPM parameters in a cohort of PPGL at our center in western India. METHODS: Retrospective study of patients with PPGL whose ABPM data was available. Demographic details, secretory status, and ABPM data were retrieved. Coefficient of variability (CV) was calculated as standard deviation/mean in percentage...
August 4, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37555421/an-unusual-case-of-facial-cutaneous-tuberculosis
#34
JOURNAL ARTICLE
X Liao, G Zhou, H Liu, F Zhang
No abstract text is available yet for this article.
August 4, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37530377/celiac-artery-thrombosis-presenting-as-acute-abdomen
#35
M Sharma, K Natarajan, A Mahesh Kumar, P Paramasivan
Mesenteric vascular thrombosis, typically of the superior mesenteric artery, is a frequent occurrence in patients with hypercoagulable conditions. Isolated involvement of the celiac artery is rare. Patients with celiac artery thrombosis can present with an acute abdomen or occasionally with acid peptic symptoms. A delay in diagnosis is associated with high rates of morbidity and mortality. We present a rare case of splenic infarction with celiac trunk thrombosis in a 54-year-old patient with underlying antiphospholipid (APLA) syndrome who presented with epigastric pain that was mistaken for symptoms of acid reflux...
July 31, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37530376/oxymorons-in-medical-imaging-flip-flops-longitudinally-transverse
#36
JOURNAL ARTICLE
S S Sankhe
No abstract text is available yet for this article.
July 28, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37530375/intraventricular-membrane-with-ventricular-diverticulum
#37
JOURNAL ARTICLE
P P Suthar, S G Dua
No abstract text is available yet for this article.
July 25, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37470633/trends-in-oral-anticoagulant-use-a-10-year-retrospective-analysis-from-a-general-medicine-department-of-a-tertiary-care-hospital-in-south-india
#38
JOURNAL ARTICLE
V V Thomas, A Lenin, T K George, M Thenmozhi, R Iyadurai, T D Sudarsanam
BACKGROUND: The prescribing practice of newer oral anticoagulants (NOACs) has not been adequately studied in the Indian scenario. AIMS: We aimed to describe the prescribing practices of oral anticoagulants, the patient profile and medical comorbidities among patients admitted in a general medicine unit. METHODS: In this retrospective study of the 2742 patients prescribed vitamin- K antagonists (VKAs), during the study period, 150 cases were randomly taken for analysis to match the 105 NOACs cases...
July 19, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37449588/trends-of-surgical-care-delivery-during-the-covid-19-pandemic-a-multi-centre-study-in-india-indsurg-collaboration
#39
JOURNAL ARTICLE
S Jain, A Mahajan, P M Patil, P Bhandarkar, M Khajanchi, IndSurg Collaboration
CONTEXT: The COVID-19 pandemic and subsequent lockdowns adversely affected global healthcare services to varying extents. To accommodate its added burden, emergency services were affected along-with elective surgeries. AIMS: To quantify and analyze the trends of essential surgeries and bellwether procedures during the waxing and waning of the pandemic, across various hospitals in India. SETTINGS AND DESIGN: Multi-centric retrospective study...
July 11, 2023: Journal of Postgraduate Medicine
https://read.qxmd.com/read/37395533/contribution-of-indian-publications-to-research-in-telemedicine
#40
JOURNAL ARTICLE
M S Tullu
No abstract text is available yet for this article.
July 3, 2023: Journal of Postgraduate Medicine
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