journal
https://read.qxmd.com/read/38385629/synergistic-effect-of-combining-dual-enkephalinase-inhibitor-pl37-and-sumatriptan-in-a-preclinical-model-of-migraine
#21
JOURNAL ARTICLE
Jeanne Rossignol, Tanja Ouimet, Hervé Poras, Radhouane Dallel, Philippe Luccarini
OBJECTIVE: The aim of this study was to test whether a combination of sumatriptan with dual enkephalinase inhibitor PL37 would result in an additive or a synergistic effect. BACKGROUND: Combination treatment is frequently used to improve the therapeutic efficacy of drugs. The co-administration of two drugs may result in efficacy at lower doses than those needed for either drug alone, thus minimizing side effects. Here, we tested the effect of the co-administration of two drugs on cutaneous mechanical hypersensitivity (MH), a symptom often affecting cephalic regions in patients with migraine: dual enkephalinase inhibitor PL37, a small molecule that protects enkephalins from rapid degradation, and sumatriptan, a serotonin 5-HT1B/1D receptor agonist...
February 22, 2024: Headache
https://read.qxmd.com/read/38318677/habitual-caffeinated-beverage-consumption-and-headaches-among-adults-with-episodic-migraine-a-prospective-cohort-study
#22
JOURNAL ARTICLE
Maggie R Mittleman, Elizabeth Mostofsky, Angeliki Vgontzas, Suzanne M Bertisch
OBJECTIVE: To examine the relationship between habitual caffeinated beverage consumption and headache frequency, duration, and intensity in a prospective cohort of adults with episodic migraine. BACKGROUND: Caffeine is a commonly ascribed headache trigger in adults with migraine and clinicians may counsel patients to avoid caffeinated beverages; however, few studies have examined this association. METHODS: From March 2016 to August 2017, 101 adults with physician-confirmed episodic migraine completed baseline questionnaires, including information about caffeinated beverage consumption...
February 6, 2024: Headache
https://read.qxmd.com/read/38288634/regulation-of-headache-response-and-transcriptomic-network-by-the-trigeminal-ganglion-clock
#23
JOURNAL ARTICLE
Chorong Han, Ji Ye Lim, Nobuya Koike, Sun Young Kim, Kaori Ono, Celia K Tran, Elizaveta Mangutov, Eunju Kim, Yanping Zhang, Lingyong Li, Amynah A Pradhan, Kazuhiro Yagita, Zheng Chen, Seung-Hee Yoo, Mark J Burish
OBJECTIVE: To characterize the circadian features of the trigeminal ganglion in a mouse model of headache. BACKGROUND: Several headache disorders, such as migraine and cluster headache, are known to exhibit distinct circadian rhythms of attacks. The circadian basis for these rhythmic pain responses, however, remains poorly understood. METHODS: We examined trigeminal ganglion ex vivo and single-cell cultures from Per2::LucSV reporter mice and performed immunohistochemistry...
January 30, 2024: Headache
https://read.qxmd.com/read/38284247/effect-of-prednisolone-for-the-treatment-of-medication-overuse-headache-a-3-month-result-from-a-multicenter-registry-for-load-and-management-of-medication-overuse-headache-release-study
#24
JOURNAL ARTICLE
Mi Ji Lee, Hong-Kyun Park, Sun-Young Oh, Jin-Ju Kang, Yooha Hong, Heui-Soo Moon, Tae-Jin Song, Min Kyung Chu, Soo-Jin Cho
OBJECTIVE: To evaluate the efficacy of prednisolone in the treatment of medication-overuse headache (MOH) using data from a multicenter prospective registry (Registry for Load and Management of Medication Overuse Headache [RELEASE]). BACKGROUND: The treatment of MOH is challenging, especially when withdrawal headache manifests during the cessation of overused medication. Although systemic corticosteroids have been empirically used to reduce withdrawal headaches, their efficacy on the long-term outcomes of MOH has not been documented...
January 29, 2024: Headache
https://read.qxmd.com/read/38284241/neuromodulation-for-primary-headache-disorders-advantages-and-challenges
#25
JOURNAL ARTICLE
Crystal Jicha, Kendra Pham
No abstract text is available yet for this article.
January 29, 2024: Headache
https://read.qxmd.com/read/38284213/daith-piercing-revisited-from-the-perspective-of-auricular-acupuncture-systems-a-narrative-review
#26
REVIEW
Saroj K Pradhan, Andreas R Gantenbein, Yiming Li, Hamdy Shaban, Xiaoying Lyu, Ahmet Sevik, Michael Furian
BACKGROUND: Daith piercing is a special ear-piercing method that punctures the crus of the helix. The penetrated site at the ear's innermost point is assumed to stimulate a pressure point associated with the vagus nerve. It has been reported that the pierced spot relieves migraine and tension-type headaches by activating vagal afferents, leading to the inhibition of neurons in the caudal trigeminal nucleus via the nucleus tractus solitarii. OBJECTIVE: The objective of this narrative literature review is to summarize the current state of knowledge concerning daith piercing for the treatment of migraine and tension-type headaches from the perspectives of the Chinese and Western auricular systems...
January 29, 2024: Headache
https://read.qxmd.com/read/38235911/metaphorical-use-of-headache-and-migraine-in-media-a-longitudinal-study-of-1-3-million-articles-in-major-publications
#27
JOURNAL ARTICLE
Pengfei Zhang, Advika Ventrapragada, Robert E Shapiro, Thien Phu Do
BACKGROUND: Stigmatization and trivialization of headache confront individuals with headache disorders, but the degree to which media may contribute is incompletely understood. OBJECTIVE: The objective of this study was to quantify the frequency of disparaging metaphorical use of the words "headache" and "migraine" in articles and summaries of major publications. METHODS: This longitudinal study analyzed a dataset of 1.3 million articles and summaries written by authors and editors of 38 major publications...
January 18, 2024: Headache
https://read.qxmd.com/read/38235829/examining-substance-use-patterns-in-adults-with-migraine-a%C3%A2-changing-landscape
#28
EDITORIAL
Angeliki Vgontzas
No abstract text is available yet for this article.
January 18, 2024: Headache
https://read.qxmd.com/read/38235605/the-impacts-of-migraine-on-functioning-results-from-two-qualitative-studies-of-people-living-with-migraine
#29
JOURNAL ARTICLE
Rikki Mangrum, Alexandra L Bryant, Maya T Gerstein, Kelly P McCarrier, Carrie R Houts, James S McGinley, Dawn C Buse, Richard B Lipton, R J Wirth
OBJECTIVE: To describe the impact of migraine on functioning based on comprehensive data collection, analysis, and reporting of patients' experiences. BACKGROUND: Qualitative research conducted to understand patients' perspectives on living with migraine has often focused on narrow topics or specific groups of patients or has been selectively reported. METHODS: Qualitative interviews with 71 participants were conducted during two concept elicitation studies as part of the Migraine Clinical Outcome Assessment System (MiCOAS) project, an FDA grant-funded program designed to develop a core set of patient-centered outcome measures for migraine clinical trials...
January 18, 2024: Headache
https://read.qxmd.com/read/38205903/epidemiology-and-clinical-features-of-paroxysmal-hemicrania-a%C3%A2-systematic-review-and-meta-analysis
#30
REVIEW
Mikkel J Henningsen, Johanne G Larsen, William K Karlsson, Rune H Christensen, Haidar M Al-Khazali, Faisal Mohammad Amin, Håkan Ashina
OBJECTIVE: To assess the prevalence or relative frequency of paroxysmal hemicrania and its clinical features in the adult general population and among adult patients evaluated for headache in tertiary care. BACKGROUND: Paroxysmal hemicrania is a rare trigeminal autonomic cephalalgia with characteristic attacks of headache, associated cranial autonomic symptoms and signs, and an absolute response to indomethacin. Its epidemiological burden remains unknown in both the adult general population and among adult patients evaluated for headache in a tertiary care setting...
January 11, 2024: Headache
https://read.qxmd.com/read/38504449/preliminary-prospective-observational-investigation-of-clinical-outcomes-among-treatment-seeking-youth-with-continuous-headache
#31
LETTER
Robert C Gibler, Kaelynn E Knestrick, Scott W Powers, Andrew D Hershey, Marielle Kabbouche, Joanne Kacperski, Brooke L Reidy
No abstract text is available yet for this article.
March 2024: Headache
https://read.qxmd.com/read/38299747/screen-time-and-pediatric-headache-a-scoping-review-of-the-literature
#32
REVIEW
Raquel L Langdon, Marc T DiSabella, Jeffrey A Strelzik
OBJECTIVE: The aim of this study was to summarize the evidence regarding screen use as a contributing factor in pediatric headache and migraine. BACKGROUND: Screen exposure is often reported as a headache trigger, though there is no current consensus in terms of how screen type, duration, or frequency influences pediatric headache and the associated burden of disease. METHODS: A systematic search in PubMed, Scopus, Cochrane Library, ProQuest Health and Medical Database, and Google Scholar was performed through November 2022 in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement...
February 2024: Headache
https://read.qxmd.com/read/38299699/substance-use-in-a-dutch-migraine-cohort-compared-with-the-general-population
#33
JOURNAL ARTICLE
Thomas C van den Hoek, Iris E Verhagen, Irene de Boer, Gisela M Terwindt
OBJECTIVE: To evaluate self-reported substance user profiles for individuals with migraine and compare these to the general population. BACKGROUND: There is increasing attention to lifestyle influences such as substance use as presumed migraine triggers. METHODS: Data on substance use were collected by survey in a large migraine cohort and from the biannual survey in the general Dutch population for substances. A representative cohort of Dutch patients with migraine (n = 5176) and the Dutch general population (n = 8370) was included...
February 2024: Headache
https://read.qxmd.com/read/38017629/effect-of-galcanezumab-in-women-with-episodic-migraine-meeting-criteria-for-menstrually-related-migraine-a-post-hoc-analysis-of-evolve-1-and-evolve-2
#34
RANDOMIZED CONTROLLED TRIAL
E Anne MacGregor, Rose Okonkwo, Holland C Detke, Pepa Polavieja, Maria S Fernandes, Jelena M Pavlovic
BACKGROUND: We evaluated galcanezumab for migraine prevention in patients who met International Classification of Headache Disorders, 3rd edition criteria for menstrually related migraine (MRM). METHODS: Patients were identified post hoc from three double-blind, randomized, phase 3 clinical trials in patients with episodic migraine. Patients completed a 1-month prospective baseline period and up to 6 months (EVOLVE-1 and -2, studies pooled) of double-blind treatment with galcanezumab (120 mg/month) or placebo...
February 2024: Headache
https://read.qxmd.com/read/38238974/cch-attack-frequency-reduction-after-psilocybin-correlates-with-hypothalamic-functional-connectivity
#35
JOURNAL ARTICLE
Martin K Madsen, Anja Sofie Petersen, Dea S Stenbaek, Inger Marie Sørensen, Harald Schiønning, Tobias Fjeld, Charlotte H Nykjaer, Sara Marie Ulv Larsen, Maria Grzywacz, Tobias Mathiesen, Ida L Klausen, Oliver Overgaard-Hansen, Kristoffer Brendstrup-Brix, Kristian Linnet, Sys S Johansen, Patrick M Fisher, Rigmor H Jensen, Gitte M Knudsen
OBJECTIVE: To evaluate the feasibility and prophylactic effect of psilocybin as well as its effects on hypothalamic functional connectivity (FC) in patients with chronic cluster headache (CCH). BACKGROUND: CCH is an excruciating and difficult-to-treat disorder with incompletely understood pathophysiology, although hypothalamic dysfunction has been implicated. Psilocybin may have beneficial prophylactic effects, but clinical evidence is limited. METHODS: In this small open-label clinical trial, 10 patients with CCH were included and maintained headache diaries for 10 weeks...
January 2024: Headache
https://read.qxmd.com/read/38238973/persistent-headache-attributed-to-past-ischemic-stroke-a-prospective-cohort-study
#36
JOURNAL ARTICLE
Felipe A A de Oliveira, Mario G Dourado-Filho, Pedro A Sampaio Rocha-Filho
OBJECTIVE: To assess the incidence, characteristics, and risk factors for developing persistent headache attributed to past ischemic stroke. BACKGROUND: Although the most recent International Classification of Headache Disorders has recognized the existence of persistent headache attributed to past ischemic stroke, there has been limited research in this area. METHODS: This was a prospective cohort study. We initially assessed patients hospitalized with ischemic stroke admitted within 72 h of symptom onset...
January 2024: Headache
https://read.qxmd.com/read/38238972/comment-on-plasma-calcitonin-gene-related-peptide-and-nerve-growth-factor-as-headache-and-pain-biomarkers-in-recently-deployed-soldiers-with-and-without-a-recent-concussion
#37
LETTER
https://read.qxmd.com/read/38238971/author-response-to-comment-on-plasma-calcitonin-gene-related-peptide-and-nerve-growth-factor-as-headache-and-pain-biomarkers-in-recently-deployed-soldiers-with-and-without-a-recent-concussion
#38
LETTER
https://read.qxmd.com/read/38235835/a-retrospective-analysis-of-the-use-of-candesartan-for-migraine-prevention-in-adolescents
#39
JOURNAL ARTICLE
Irene Patniyot, Ankona Banerjee, Kenneth Nobleza, Duc Nguyen, Deanna Duggan, Michelle Holick, Holly Dudley-Harrell
No abstract text is available yet for this article.
January 2024: Headache
https://read.qxmd.com/read/38156514/bone-site-fracture-pain-after-subcutaneous-sumatriptan-injection-a-report-of-two-cases
#40
LETTER
Marion Beltramone, Sylvain Redon, Anne Donnet
No abstract text is available yet for this article.
January 2024: Headache
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