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Journals South African Journal of Surge...

South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie

https://read.qxmd.com/read/38838129/does-hiv-co-infection-promote-echinococcus-dissemination
#1
JOURNAL ARTICLE
K Couzens-Bohlin, J E J Krige, P Keshaw, H Allam, E Jonas
The influence of human immunodeficiency virus (HIV) on the severity of hepatic cystic echinococcosis (CE) is uncertain. HIV-modulated immune suppression may increase the risk of contracting CE with less self-limiting disease, more rapid progression, and a higher likelihood of complications. A 30-year-old male with concurrent, untreated HIV underwent surgery for two large, complicated hepatic CE cysts, which were replacing the right hemiliver, and innumerable peritoneal daughter cysts. At operation, 30 kg of cystic material was removed from the liver and peritoneal cavity...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838128/can-cannabinoids-contribute-to-cholecystitis-a-case-of-gangrenous-acalculous-cholecystitis
#2
JOURNAL ARTICLE
M Bhana, Y Perner
Cannabis legalisation continues to grow globally and its effects on the vascular system have been scrutinized.1 Cannabis has become recognised as a contributor to cardiovascular, cerebrovascular and peripheral vascular disease.2,3 This case report highlights the case of a young male patient presenting with atypical symptoms following cannabis use who developed gangrenous cholecystitis (GC) following vasospasm of his cystic artery. We believe that this is the first-ever case, shared with the anticipation of stimulating more research and prompting recognition of vascular events in this group of patients as our knowledge on the effects of cannabis continues to grow...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838127/ct-scan-the-key-to-unmasking-a-solid-pseudopapillary-pancreatic-neoplasm-in-blunt-abdominal-trauma
#3
JOURNAL ARTICLE
R D Marshall, J E van Schalkwyk, S Hofmeyr, W Conradie
We present a previously healthy 13-year-old male, who sustained a handlebar injury after falling from his bicycle. The computerised tomography (CT) scan indicated a probable pancreatic neoplasm associated with a retroperitoneal haematoma which was, following resection, confirmed histologically to be a solid pseudopapillary neoplasm of the pancreas. These are rare tumours of the pancreas, especially in young males. The rarity of this neoplasm and the mechanism that led to its presentation make this an interesting and unique case...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838126/misinterpretation-of-the-severity-of-bile-duct-injuries-by-mrcp
#4
JOURNAL ARTICLE
M Bhana, M Bernon, J C Kloppers, E Jonas
BACKGROUND: Magnetic resonance imaging (MRI) is widely regarded as the gold standard for assessment of the bile ducts in patients with bile duct injuries (BDIs). This case series aims to highlight the shortcomings of this imaging modality and demonstrate how it may overestimate the injury severity. METHODS: Three patients treated at Groote Schuur Hospital and the University of Cape Town in whom MRI/magnetic resonance cholangiopancreatography (MRCP) overestimated the severity of BDI were included in the study...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838125/30-day-outcomes-in-1-000-consecutive-laparoscopic-cholecystectomies-undertaken-in-four-cape-metropole-public-hospitals
#5
MULTICENTER STUDY
M Kariem, F Gool, N Kariem, N Karimbocus, J C Kloppers
BACKGROUND: Laparoscopic cholecystectomy (LC) is the standard of care for symptomatic gallstone disease. The procedure has a steep learning curve and may result in significant postoperative morbidity and mortality. LC carries a morbidity of 1.6-5.3%, a mortality of 0.05-0.14% and readmission rates of 3.3% (0-11.7%). We aimed to evaluate the 30-day outcomes of LC across four metropole hospitals in the Western Cape (WC) including mortality, length of stay, readmissions and complications according to the Clavien-Dindo classification system...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838124/audit-of-an-in-patient-palliative-care-quality-improvement-process-for-patients-with-pancreatic-ductal-adenocarcinoma-in-a-south-african-teaching-hospital
#6
JOURNAL ARTICLE
U K Kotze, R Krause, M Bernon, L Gwyther, J Olivier, E Jonas
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor survival rates. Timeously introduced palliative care (PC) improves the quality of life (QoL) for patients with terminal diseases. In 2020, an in-patient PC-quality improvement (QI) programme was implemented for PDAC patients. This study compared PC outcomes before and after the introduction of the PC-QI programme. METHODS: A focus group identified five critical intervention areas that could improve care...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838123/effect-of-preoperative-biliary-drainage-on-intraoperative-biliary-cultures-and-surgical-outcomes-after-pancreatic-resection
#7
JOURNAL ARTICLE
M M Bernon, S Steenkamp, S Dlamini, M Miller, S Sobnach, N Leech, U Kotze, J E J Krige, E G Jonas
BACKGROUND: Prolonged obstructive jaundice (OJ), associated with resectable pancreatic pathology, has many deleterious effects that are potentially rectifiable by preoperative biliary drainage (POBD) at the cost of increased postoperative infective complications. The aim of this study is to assess the impact of POBD on intraoperative biliary cultures (IBCs) and surgical outcomes in patients undergoing pancreatic resection. METHODS: Data from patients at Groote Schuur Hospital, Cape Town, between October 2008 and May 2019 were analysed...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838122/the-role-of-endoscopic-retrograde-cholangiopancreatography-in-the-treatment-of-hepatic-cystic-echinococcus-in-a-high-hiv-prevalence-population-a-retrospective-cohort-study
#8
JOURNAL ARTICLE
K Couzens-Bohlin, J E J Krige, J Malherbe, U K Kotze, R Khan, E Jonas
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is a useful, minimally invasive intervention in managing complicated hepatic cystic echinococcosis (HCE). This study aims to assess the use of ERCP in a South African HCE cohort with and without human immunodeficiency virus (HIV) co-infection. METHODS: An analysis was performed of patients with HCE who were assessed for surgery and underwent ERCP at a tertiary hospital in South Africa between 2011 and 2023...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838121/intermediate-and-long-term-survival-prediction-using-prognostic-scores-in-patients-undergoing-salvage-tips-for-uncontrolled-variceal-bleeding
#9
JOURNAL ARTICLE
J E J Krige, E G Jonas, M Setshedi, S J Beningfield, U K Kotze, M M Bernon, S Burmeister, J C Kloppers
BACKGROUND: This study investigated the value of prognostic scores to predict 90-day, 1-, 3- and 5-year survival after salvage TIPS (sTIPS) in patients with exsanguinating variceal bleeding who failed endoscopic intervention. METHODS: The Model for End-Stage Liver Disease (MELD), Model for End-Stage Liver Disease Sodium (MELDNa), Acute Physiology and Chronic Health Evaluation II (APACHE II) and Child-Pugh (C-P) grades and scores were calculated using Kaplan-Meier curves and Cox proportional hazards models in sTIPS patients treated between August 1991 and November 2020...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838120/predicting-gallstone-pancreatitis-in-hiv-infected-patients
#10
JOURNAL ARTICLE
F Anderson, T E Madiba, S R Thomson
BACKGROUND: Human immunodeficiency virus (HIV) infection, low cluster of differentiation (CD)4 counts and antiretroviral therapy can cause cholestasis and raised transaminases. In acute pancreatitis, this may render biochemical predictors of a gallstone aetiology inaccurate. METHODS: In a prospective observational study, acute pancreatitis was diagnosed by standard criteria. Cholecystolithiasis and bile duct diameter were diagnosed by ultrasound. Cholestasis was defined as two of the following: bilirubin ≥ 21 umol/l, γ glutamyl transferase ≥ 78 U/l, alkaline phosphatase ≥ 121 U/l...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838119/association-between-chronic-pancreatitis-and-pancreatic-cancer-at-a-central-hospital-in-kwazulu-natal-south-africa
#11
JOURNAL ARTICLE
F G Madela, M S A Sithole, N C Ntanzi, K S Chiliza, S Kader, A Mwazha, S R Thomson, C Aldous
BACKGROUND: The frequency of histological chronic pancreatitis (CP) evidence in the resident pancreas of resected periampullary cancers (PACs) has never been studied in Africa. This study aims to describe the spectrum of pathology and outcomes of pancreatic surgeries and address this deficit from a South African central hospital cohort. METHODS: A retrospective audit of patients undergoing pancreatic surgery at Inkosi Albert Luthuli Central Hospital (IALCH) between 2003 and 2023 was conducted...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838118/pancreaticoduodenectomy-for-distal-cholangiocarcinoma-at-a-south-african-centre
#12
JOURNAL ARTICLE
R Alnaqbi, M Bernon, M Emmamally, R Khan, U K Kotze, J E J Krige, E G Jonas, S Sobnach
BACKGROUND: Surgical resection of distal cholangiocarcinoma (dCCA) offers the only chance for cure and long-term survival. The current literature provides limited data regarding the surgical management and long-term outcomes of dCCA. This study aims to describe the presentation, management, and outcomes of dCCA at a large academic referral centre in South Africa. METHODS: A retrospective study was performed of all patients who underwent curative-intended surgery for dCCA at Groote Schuur Hospital from 2000 to 2020...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838117/does-the-textbook-outcome-in-pancreatic-surgery-score-after-pancreaticoduodenectomy-for-ampullary-carcinoma-have-prognostic-value
#13
JOURNAL ARTICLE
N Leech, J E J Krige, S Sobnach, J C Kloppers, M M Bernon, S Burmeister, E G Jonas
BACKGROUND: The value of the textbook outcome in pancreatic surgery (TOPS) score, a composite measure of surgical performance for quality assurance, was evaluated in a South African tertiary hospital cohort of pancreaticoduodenectomies (PD) performed for adenocarcinoma of the ampulla of Vater (AAV). METHODS: A review of all patients undergoing a PD for AAV at a single centre between January 1999 and December 2023 was performed. Demographic, operative, pathological and postoperative variables were recorded...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838116/isolated-roux-en-y-versus-single-loop-pancreaticojejunal-reconstruction-after-pancreaticoduodenectomy-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#14
COMPARATIVE STUDY
E E D Abu-Zeid, I U Garzali, A Aloun, A A Sheshe
BACKGROUND: Pancreaticoduodenectomy is a complex intra-abdominal operation used for the treatment of benign and malignant disease of the pancreatic head or periampullary region. Despite developments in surgical techniques, pancreaticoduodenectomy is still associated with high rate of postoperative complications. We performed this systematic review and meta-analysis to compare the surgical outcomes of isolated Roux-en-Y pancreaticojejunostomy (IRYPJ), and conventional pancreaticojejunostomy(CPJ)...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838115/inflammatory-myofibroblastic-tumours-of-the-liver-a-systematic-review
#15
JOURNAL ARTICLE
M Li, S Sobnach, U K Kotze, L F Zerbini, J M Millis, D A Hampton, M M Bernon, J E J Krige, E G Jonas
BACKGROUND: Hepatic inflammatory myofibroblastic tumours (HIMTs) are rare and poorly described in the literature. Most publications are single patient case reports and lack detailed reporting on characteristics, management, and outcomes. This systematic review aimed to assess the demography, clinical presentation, typical imaging features, histopathology, treatment, and outcomes of patients presenting with HIMTs. METHODS: A systematic literature search was performed in MEDLINE (PubMed), EMBASE (Scopus), JSTOR, Cochrane CENTRAL (Cochrane Library), and the databases included in the Web of Science for studies published between 1940 and 2023 on HIMTs, including its reported synonyms...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838114/outcomes-of-jaundice-in-advanced-hepatocellular-carcinoma-a-sub-saharan-perspective
#16
JOURNAL ARTICLE
P B Keshaw, M Bernon, M Emmamally, R Khan, R Segobin, D Creamer, J E J Krige, E Jonas, S Sobnach
BACKGROUND: Jaundice is a marker of advanced disease and poor outcomes in hepatocellular carcinoma (HCC). The aim of this study was to describe and analyse the management and outcomes of jaundiced HCC patients at a large academic referral centre in sub-Saharan Africa (SSA). METHODS: Treatment-naïve adult HCC patients who presented with jaundice between 1990 and 2023 were analysed. RESULTS: During the inclusion period, 676 HCC patients were treated at Groote Schuur Hospital...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838113/liver-resection-for-hepatocellular-and-fibrolamellar-carcinoma-in-a-south-african-tertiary-referral-centre-an-observational-cohort-analysis
#17
JOURNAL ARTICLE
Y Ziaei, J E J Krige, E G Jonas, U K Kotze, M M Bernon, C Kloppers, S Sobnach
BACKGROUND: More than 80% of global hepatocellular carcinomas (HCC) occur in sub-Saharan Africa (SSA) and South- East Asia. Compared with the rest of the world, HCC in SSA has the lowest resection and survival rates. This study assessed outcome following liver resection for HCC and fibrolamellar carcinoma (FLC) at a tertiary referral centre in South Africa. METHODS: A retrospective analysis was done of all liver resections for HCC and FLC at Groote Schuur Hospital and the University of Cape Town Private Academic Hospital between January 1990 and December 2021...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838112/new-horizons-in-liver-transplantation-for-hepatocellular-carcinoma
#18
REVIEW
J Lindemann, J Yu, M M B Doyle
Primary liver cancer was the third most common cause of death due to cancer worldwide in 2020. As the predominant type, hepatocellular carcinoma (HCC) represents the overwhelming majority of newly diagnosed primary liver tumours. Liver transplantation remains the treatment of choice for a cure in otherwise unresectable HCC. For nearly thirty years, the Milan and Barcelona Clinic Liver Cancer (BCLC) criteria have guided physicians' clinical decision-making for selection of liver transplant candidates in the treatment of HCC...
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838111/hpbasa-from-inception-to-maturity
#19
EDITORIAL
J Devar, M Smith
No abstract text is available yet for this article.
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/38838110/editorial
#20
EDITORIAL
J E J Krige, E Jonas
No abstract text is available yet for this article.
May 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
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