Yehuda Warszawer, Michael Gurevich, Ariel Kerpel, Sapir Dreyer Alster, Yael Nissan, Emanuel Shirbint, Chen Hoffmann, Anat Achiron
PURPOSE: Detection and prediction of the rate of brain volume loss with age is a significant unmet need in patients with primary progressive multiple sclerosis (PPMS). In this study we construct detailed brain volume maps for PPMS patients. These maps compare age-related changes in both cortical and sub-cortical regions with those in healthy individuals. METHODS: We conducted retrospective analyses of brain volume using T1-weighted Magnetic Resonance Imaging (MRI) scans of a large cohort of PPMS patients and healthy subjects...
April 13, 2024: Neuroradiology
Costanza Parodi, Margherita Aluffi Valletti, Domenico Tortora, Silvia Buratti, Marisa Mallamaci, Giulia Tuo, Angela Pistorio, Andrea Moscatelli, Andrea Rossi, Mariasavina Severino
PURPOSE: To validate a semiautomated method for segmenting vein of Galen aneurysmal malformations (VGAM) and to assess the relationship between VGAM volume and other angioarchitectural features, cardiological findings, and outcomes. METHODS: In this retrospective study, we selected all subjects with VGAM admitted to the Gaslini Children's Hospital between 2009 and 2022. Clinical data were retrieved from electronic charts. We compared 3D-Slicer segmented VGAM volumes obtained by two independent observers using phase-contrast MR venography to those obtained with manual measurements performed on T2-weighted images...
April 12, 2024: Neuroradiology
Masaya Kawaguchi, Hiroki Kato, Tomohiro Kanayama, Hiroyuki Tomita, Akira Hara, Hirofumi Shibata, Takenori Ogawa, Daijiro Hatakeyama, Yoichi Yamada, Tomohiro Ando, Yoshifumi Noda, Fuminori Hyodo, Masayuki Matsuo
PURPOSE: This study aimed to compare the radiological tumor (T)-category using multiparametric MRI with the pathological T category in patients with oral tongue squamous cell carcinoma (OTSCC) and to examine which is a better predictor of prognosis. METHODS: This retrospective study included 110 consecutive patients with surgically resected primary OTSCC who underwent preoperative contrast-enhanced MRI. T categories determined by maximum diameter and depth of invasion were retrospectively assessed based on the pathological specimen and multiparametric MRI...
April 12, 2024: Neuroradiology
Antonios Kagialis, Nicholas Simos, Katina Manolitsi, Antonios Vakis, Panagiotis Simos, Efrosini Papadaki
PURPOSE: To examine hemodynamic and functional connectivity alterations and their association with neurocognitive and mental health indices in patients with chronic mild traumatic brain injury (mTBI). METHODS: Resting-state functional MRI (rs-fMRI) and neuropsychological assessment of 37 patients with chronic mTBI were performed. Intrinsic connectivity contrast (ICC) and time-shift analysis (TSA) of the rs-fMRI data allowed the assessment of regional hemodynamic and functional connectivity disturbances and their coupling (or uncoupling)...
April 12, 2024: Neuroradiology
Annette Karimi, Sirkku Setänen, Eva Larsson, Gerd Holmström, Ylva Fredriksson Kaul, Olga Kochukhova, Martin Johansson, Cecilia Montgomery, Lena Hellström-Westas, Johan Wikström
No abstract text is available yet for this article.
April 10, 2024: Neuroradiology
Zhenhao Liu, Shiyu Zhang, Yuxin Wang, Hui Xu, Yongqiang Gao, Hong Jin, Yufeng Zhang, Hongyang Wu, Jun Lu, Peipei Chen, Peng-Gang Qiao, Zhenghan Yang
PURPOSE: Posterior circulation ischemic stroke (PCIS) possesses unique features. However, previous studies have primarily or exclusively relied on anterior circulation stroke cases to build machine learning (ML) models for predicting onset time. To date, there is no research reporting the effectiveness and stability of ML in identifying PCIS onset time. We aimed to build diffusion-weighted imaging-based ML models to identify the onset time of PCIS patients. METHODS: Consecutive PCIS patients within 24 h of definite symptom onset were included (112 in the training set and 49 in the independent test set)...
April 9, 2024: Neuroradiology
Xinjie Zhang, Zhuang Sha, Dongyi Feng, Chenrui Wu, Ye Tian, Dong Wang, Junping Wang, Rongcai Jiang
PURPOSE: To develop and validate a prediction model based on imaging data for the prognosis of mild chronic subdural hematoma undergoing atorvastatin treatment. METHODS: We developed the prediction model utilizing data from patients diagnosed with CSDH between February 2019 and November 2021. Demographic characteristics, medical history, and hematoma characteristics in non-contrast computed tomography (NCCT) were extracted upon admission to the hospital. To reduce data dimensionality, a backward stepwise regression model was implemented to build a prognostic prediction model...
April 8, 2024: Neuroradiology
Dewansh Mishra, Santhosh Kumar Kannath, Jayadevan Er, Bejoy Thomas, C Kesavadas
PURPOSE: Endovascular treatment of direct carotid cavernous fistula (DCCF) requires invasive diagnostic cerebral angiography for diagnosis and planning; however, a less invasive modality like magnetic resonance angiography (MRA) can be useful, especially in high-risk cases. This single-centre study evaluated a newer MR angiography (MRA) sequence, silent MRA and the traditional time of flight (TOF) MRA for pre-procedural treatment planning of DCCF. METHODS: All consecutive DCCF patients who underwent TOF, silent MRA and diagnostic cerebral angiography were included in the study...
April 6, 2024: Neuroradiology
Stefano Marcia, Josh Adam Hirsh, Matteo Bellini, Giulia Sadotti, Luigi Manfré, Aldo Eros De Vivo, Emanuele Piras, Giacomo Zini, Chiara Zini
PURPOSE: To evaluate safety and efficacy of the novel percutaneous interspinous device (PID) for the treatment of symptomatic degenerative lumbar spinal stenosis (DLSS) in 3 different centers. METHODS: From November 2016 to March 2020, 255 patients (male 125, mean age 71.2 years old range 49-91 years old) with neurogenic claudication, confirmed by electromyography, related to mono or bi-segmental lumbar central canal and/or foraminal stenosis were enrolled in the study...
April 3, 2024: Neuroradiology
Jiahao Li, Lingmei Ai, Ruoxia Yao
PURPOSE: Diffusion magnetic resonance imaging (dMRI) is a widely used non-invasive method for investigating brain anatomical structures. Conventional techniques for estimating fiber orientation distribution (FOD) from dMRI data often neglect voxel-level spatial relationships, leading to ambiguous associations between target voxels and their neighbors, which, in turn, adversely impacts FOD accuracy. This study aims to address this issue by introducing a novel neural network, the neighboring voxel attention mechanism network (NVAM-Net), designed to reconstruct high-quality FOD images...
April 2, 2024: Neuroradiology
Valerio Da Ros, Federico Sabuzi, Francesco D'Argento, Alessandro Pedicelli, Vladimir Gavrilovic, Massimo Sponza, Francesca Di Giuliano, Francesco Biraschi, Marta Iacobucci, Giovanni Grillea, Andrea Bartolo, Mirko Patassini, Paolo Remida, Luca Quilici, Giuseppe Faragò, Marco Varrassi, Nicola Cavasin, Roberto Arpesani, Aldo Victor Giordano, Giuseppe Umana, Francesco Garaci, Roberto Floris
PURPOSE: The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista "Mama" (SVM) flow diverter (BALT, Montmorency, France) for the treatment of proximal intracranial aneurysms. METHODS: Between August 2020 and March 2022, data from nine Italian neurovascular centres were collected. Data included patients' clinical presentation, aneurysms' size, location and status, technical details, overall complications and mid- to long-term angiographic follow-up...
April 2, 2024: Neuroradiology
Nisar A Wani, Ishaq Malik, Syed Tariq, Abdus Sami Bhat, Umar Amin Qureshi
BACKGROUND: Thiamine deficiency disease may occur in infants from thiamine-deficient mothers in developing countries, as well as in infants fed solely with soy-based formula. Thiamine deficiency in infants may present with acute neurological manifestations of infantile encephalitic beriberi. OBJECTIVE: To review the role of noncontrast CT brain findings in infantile encephalitic beriberi in early diagnosis. MATERIALS AND METHODS: A retrospective review of noncontrast CT scans of the brain in 21 infants with acute-onset infantile encephalitic beriberi was carried out...
April 1, 2024: Neuroradiology
Rita Ferreira, António J Bastos-Leite
We reviewed 33 original research studies assessing brain perfusion, using consensus guidelines from a "white paper" issued by the International Society for Magnetic Resonance in Medicine Perfusion Study Group and the European Cooperation in Science and Technology Action BM1103 ("Arterial Spin Labelling Initiative in Dementia"; ). The studies were published between 2011 and 2023 and included participants with subjective cognitive decline plus; neurocognitive disorders, including mild cognitive impairment (MCI), Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD), dementia with Lewy bodies (DLB) and vascular cognitive impairment (VCI); as well as schizophrenia spectrum disorders, bipolar and major depressive disorders, autism spectrum disorder, attention-deficit/hyperactivity disorder, panic disorder and alcohol use disorder...
March 27, 2024: Neuroradiology
Kenta Nakase, Ichiro Nakagawa, Ai Okamoto, Yudai Morisaki, Ryousuke Maeoka, Shohei Yokoyama, Masashi Kotsugi
Understanding the risks of contrast-induced encephalopathy (CIE), a serious complication of contrast agents, is crucial in endovascular treatment. We present the case of a 73-year-old woman who developed CIE in the medulla and cervical cord during coil embolization for unruptured left basilar-superior cerebellar artery and basilar artery tip aneurysms. The CIE was identified via neuromonitoring. In this case, spinal cord ischemia might have occurred due to reduced perfusion pressure after inserting the distal access catheter (DAC) in the vertebral artery...
March 26, 2024: Neuroradiology
Kaifu Wu, Han Li, Yuanliang Xie, Shutong Zhang, Xiang Wang
PURPOSE: We sought to use the fractional amplitude of low-frequency fluctuation (fALFF) method to investigate the changes in spontaneous brain activity in CSM patients and their relationships with clinical features. METHODS: We recruited 20 patients with CSM, and 20 healthy controls (HCs) matched for age, sex, and education status. The fALFF method was used to evaluate the altered spontaneous brain activities. The Pearson correlation analysis of fALFF and the clinical features were carried out...
March 26, 2024: Neuroradiology
Nana Fujita, Koichiro Yasaka, Sosuke Hatano, Naoya Sakamoto, Ryo Kurokawa, Osamu Abe
PURPOSE: We investigated whether the quality of high-resolution computed tomography (CT) images of the temporal bone improves with deep learning reconstruction (DLR) compared with hybrid iterative reconstruction (HIR). METHODS: This retrospective study enrolled 36 patients (15 men, 21 women; age, 53.9 ± 19.5 years) who had undergone high-resolution CT of the temporal bone. Axial and coronal images were reconstructed using DLR, HIR, and filtered back projection (FBP)...
March 22, 2024: Neuroradiology
Francesco Sanvito, Anna Pichiecchio, Matteo Paoletti, Giacomo Rebella, Martina Resaz, Luana Benedetti, Federico Massa, Silvia Morbelli, Eduardo Caverzasi, Carlo Asteggiano, Pietro Businaro, Stefano Masciocchi, Lucio Castellan, Diego Franciotta, Matteo Gastaldi, Luca Roccatagliata
Autoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central nervous system. While originally described as a paraneoplastic inflammatory phenomenon affecting limbic structures, numerous instances of non-paraneoplastic pathogenesis, as well as extra-limbic involvement, have been characterized. Given the wide spectrum of insidious clinical presentations ranging from cognitive impairment to psychiatric symptoms or seizures, it is crucial to raise awareness about this disease category...
March 20, 2024: Neuroradiology
Hangzhi Liu, Changyu Zhu, Xinyan Wang, Xiaohong Chen, Zhixin Li, Junfang Xian
PURPOSE: This study aimed to develop a multisequence MRI-based volumetric histogram metrics model for predicting pathological complete response (pCR) in advanced head and neck squamous cell carcinoma (HNSCC) patients undergoing neoadjuvant chemo-immunotherapy (NCIT) and compare its predictive performance with AJCC staging and RECIST 1.1 criteria. METHODS: Twenty-four patients with locally advanced HNSCC from a prospective phase II trial were enrolled for analysis...
March 20, 2024: Neuroradiology
Alexander Rau, Marco Reisert, Thomas Stein, Katharina Mueller-Peltzer, Stephan Rau, Fabian Bamberg, Christian A Taschner, Horst Urbach, Elias Kellner
PURPOSE: CT perfusion of the brain is a powerful tool in stroke imaging, though the radiation dose is rather high. Several strategies for dose reduction have been proposed, including increasing the intervals between the dynamic scans. We determined the impact of temporal resolution on perfusion metrics, therapy decision, and radiation dose reduction in brain CT perfusion from a large dataset of patients with suspected stroke. METHODS: We retrospectively included 3555 perfusion scans from our clinical routine dataset...
March 18, 2024: Neuroradiology
Leonie Zerweck, Rolf Pohmann, Uwe Klose, Petros Martirosian, Patrick Haas, Ulrike Ernemann, Nadia Khan, Constantin Roder, Till-Karsten Hauser, Florian Hennersdorf
PURPOSE: Vessel-encoded arterial spin labeling (VE-ASL) is able to provide noninvasive information about the contribution of individual arteries to the cerebral perfusion. The aim of this study was to compare VE-ASL to the diagnostic standard digital subtraction angiography (DSA) with respect to its ability to visualize vascular territories. METHODS: In total, 20 VE-ASL and DSA data sets of 17 patients with Moyamoya angiopathy with and without revascularization surgery were retrospectively analyzed...
March 16, 2024: Neuroradiology
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