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https://read.qxmd.com/read/30997867/rationale-in-diagnosis-and-management-role-of-screening-and-history-taking
#1
Sajitha Venkatesan, Pugazhenthan Thangaraju
No abstract text is available yet for this article.
April 18, 2019: Tropical Doctor
https://read.qxmd.com/read/30991906/clinical-null-hypothesis-fisher-revisited
#2
Nadarajah Sreeharan
No abstract text is available yet for this article.
April 16, 2019: Tropical Doctor
https://read.qxmd.com/read/30967096/switching-to-secukinumab-in-difficult-to-treat-psoriasis-recalcitrant-to-methotrexate-cyclosporine-and-leflunomide-in-a-tuberculosis-endemic-country
#3
Aastha Gupta, Kabir Sardana, Ram K Gautam
Several biological agents have been approved for the treatment of recalcitrant psoriasis. However, there is a lack of a consensus algorithm guiding the drug selection for patients who have failed conventional drugs. In cases not improving with cyclosporine, direct switching to a biological therapy usually leads to a disease flare owing to increased production of interleukin (IL)-17A. Thus, secukinumab, a rapidly acting anti-IL-17A drug, may be ideal in such situations.
April 9, 2019: Tropical Doctor
https://read.qxmd.com/read/30943888/revisiting-abo-incompatibility-as-a-risk-factor-for-significant-neonatal-hyperbilirubinemia
#4
Ritika Khurana, Prerna Batra, Mma Faridi, Nirupama Khan
Babies with ABO incompatibility are often advised frequent biochemical screening and prolonged hospital stay. Our primary objective of the study was to compare serum bilirubin levels at 48 h and 96 h of age in neonates with and without ABO incompatibility. Our prospective study included neonates with gestation ≥ 34 weeks, with or without ABO incompatibility (92 in each group). A direct Coombs test was performed on cord blood. The mean serum bilirubin and haematocrit levels in both groups at 48 h and 96 h were comparable...
April 3, 2019: Tropical Doctor
https://read.qxmd.com/read/30939997/the-relation-of-toddy-palm-wine-intake-to-amoebic-liver-abscess-in-a-predominantly-toddy-drinking-population-a-cross-sectional-study
#5
Ashish Kumar Jha, Praveen Jha, Madhur Chaudhary, Shailesh Kumar, Vidyut Prakash, Vishwa Mohan Dayal
The role of toddy (palm wine) as an independent risk factor for amoebic liver abscess (ALA) is not clear. In a cross-sectional study, the clinico-demographic profiles of inpatients with ALA were examined. Microscopy examination of toddy (n = 43) samples was performed. A total of 198 patients with ALA were enrolled, most of whom were: admitted during the May-August months (48%); chronic alcoholic (85% [70% toddy]); malnourished (85%); and of low socioeconomic status (88%). Clinical and laboratory parameters were comparable between toddy and distilled alcohol drinkers...
April 2, 2019: Tropical Doctor
https://read.qxmd.com/read/30917771/doctors-and-torture
#6
Michael Cotton
No abstract text is available yet for this article.
March 27, 2019: Tropical Doctor
https://read.qxmd.com/read/30898052/perinatal-transmission-of-dengue-infection-in-a-preterm-neonate-a-case-report
#7
Jenisha Jain, Lakshmi V, Shanmughsundaram R
Dengue infection during pregnancy carries the risk of vertical transmission to the fetus and newborn. This is higher if the infection occurs late in pregnancy and the mother delivers at the height of viremia. In such a scenario, both mother and neonate are at risk of life-threatening complications. We present an interesting case of dengue infection in a preterm neonate managed at our unit.
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30898051/parotitis-coexisting-with-kawasaki-disease-in-a-child-a-rare-presentation-of-kawasaki-disease
#8
Şule Gökçe, Nida Uysal, Hasret Erkmen, Eser Doğan, Feyza Koç
Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome and infantile polyarteritis nodosa, is known to present in multiple ways. Although inflammatory changes in several systems have been reported in KD, there are few documented child patients presenting with parotitis. We report such a case in a five-year-old.
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30898046/the-brutality-of-the-sudanese-government-against-doctors-is-determined-by-policy-rather-than-isolated-events
#9
Osama Mahmoud
No abstract text is available yet for this article.
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30895888/microfilaria-not-always-associated-with-eosinophilia
#10
Neha Garg, Shilpi More, Monika Sharma, Mrinalini Kotru
Filariasis is a parasitic infection seen predominantly in tropical and subtropical countries including India. In clinically suspected cases, examining a thick wet mount smear or a buffy coat film is most informative. In unsuspected cases, however, eosinophilia in a peripheral blood smear (PBS) may be the sole indicator of parasitaemia. A few cases of tissue microfilaria with the absence of peripheral blood eosinophilia (PBE) have been reported. Here, we report two cases of microfilaria in PBS in the absence of PBE...
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30895887/guillain-barre-syndrome-a-rare-complication-of-leptospirosis-and-scrub-typhus-co-infection
#11
Nishant Dev, Rahul Kumar, Dilip Kumar
Guillain-Barré syndrome (GBS) is a potentially life-threatening immune-mediated acute inflammatory polyneuropathy associated with several antecedent infections. We report a 20-year-old man with GBS associated with concurrent leptospirosis and scrub typhus infection. GBS was confirmed with clinical examination and nerve conduction studies. There have been case reports of GBS in association with Leptospira and Orienta tsusugamushi separately. However, this may be the first case report of GBS associated with concurrent diseases...
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30895886/atypical-clinical-presentation-of-visceral-leishmaniasis-a-rare-case-without-splenomegaly
#12
Mirella Alves Cunha, Amanda Ginani Antunes, Marcela Mara Eufrasio de Azevedo, James Farley Rafael Maciel, Henio Godeiro Lacerda
Clinical manifestations of visceral leishmaniasis (VL) usually include splenomegaly. We report a case of a woman from an endemic area with fever but normal splenic size. This is rare, especially in patients not immunocompromised.
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30895885/brucellosis-after-dengue
#13
Ashok Kumar Pannu, Sanju Pannu
Zoonoses such as Brucella, Mycobacterium bovis, Campylobacter, Salmonella, Escherichia coli, Listeria, etc. are spread by ingestion of contaminated unpasteurised milk products (from infected cattle) and result in infectious outbreaks, hospitalisations and mortality. In Southeast Asian countries, raw goat's milk is sometimes used for dengue infection-associated thrombocytopenia; however, evidence to support this sociocultural practice is lacking. A peak incidence of brucellosis cases may occur after a dengue season in communities where this practice is prevalent...
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30895884/osteopetrosis-presenting-as-maxillary-osteomyelitis
#14
Sourabh Gupta, Ruchika Kumar, Archana Agrawal
Osteopetrosis is a rare congenital disease presenting with recurrent fractures, hematopoietic insufficiency and hepatosplenomegaly. Though osteomyelitis is a known complication in osteopetrosis, osteopetrosis presenting as osteomyelitis is rare. Management consists of multidisciplinary approach for complications and bone marrow transplant for the infantile form of disease.
March 21, 2019: Tropical Doctor
https://read.qxmd.com/read/30885057/the-burden-and-risk-factors-for-postnatal-depression-and-depressive-symptomatology-among-women-in-kampala
#15
Margaret Nampijja, Barnabas Natamba, Richard Mpango, Eugene Kinyanda
Major depressive disorder (MDD) is a major global health challenge and postnatal women may be at an increased risk for this disorder. Very few studies have tested this hypothesis in sub-Saharan Africa (SSA), so it is uncertain whether risk factors implicated elsewhere in the world are relevant in SSA. We explored prevalence and risk factors for MDD and depressive symptomatology among postnatal mothers in Kampala. Three hundred postnatal mothers at Nsambya Hospital were assessed for MDD using the DSM IV-based MINI; prevalence and risk factors were determined using frequencies and regressions, respectively...
March 18, 2019: Tropical Doctor
https://read.qxmd.com/read/30885056/successful-treatment-of-xdr-tb-patient-in-tanzania-report-of-the-first-xdr-tb-patient
#16
Dennis Lyakurwa, Johnson Lyimo, Liberate Mleoh, Kisonga Riziki, Mrisho Lupinda, Bonaventura Ct Mpondo
Drug-resistant tuberculosis (TB) is emerging as a new and serious public health challenge. We present the first case with confirmed extensive drug-resistant TB in Tanzania in a patient who had prior exposure to anti-TB drugs and a history of imprisonment in South Africa. The addition of bedaquiline to the treatment regime resulted in positive to negative sputum conversion. After a total of 30 months on treatment he was declared cured, remaining clinically stable and culture-negative throughout the follow-up...
March 18, 2019: Tropical Doctor
https://read.qxmd.com/read/30885055/granulomatous-inflammation-still-fooling-surgeons
#17
Prashant Durgapal, Prashant P Joshi, Ashish Gupta, Amit Gupta, Sanjeev Kishore, Ashok Singh
No abstract text is available yet for this article.
March 18, 2019: Tropical Doctor
https://read.qxmd.com/read/30885054/irritable-bowel-syndrome-in-egyptian-patients-plausible-risk-factors-and-association-with-intestinal-protozoa
#18
Aziza I Salem, Hend A El-Taweel, Marwa A Madkour, Naglaa F Abd El-Latif, Ebtesam S Abd-Elrazeq
The pathogenesis of irritable bowel syndrome (IBS) is not yet clear. Our study suggested parasitic infection and other plausible risk factors among Egyptian IBS patients. We studied 40 IBS patients diagnosed according to Rome III criteria (Group I), 40 with other gastrointestinal symptoms (Group II) and 40 healthy controls (Group III). Stool samples were examined using direct wet smear, sedimentation technique, trichrome stain and immune-chromatographic tests for Cryptosporidium parvum. IBS patients displayed a significantly greater percentage of Blastocystis hominis infection (45%) than non-IBS patients (20%) and healthy controls (10%)...
March 18, 2019: Tropical Doctor
https://read.qxmd.com/read/30871417/reliability-of-coeliac-serology-in-monitoring-dietary-adherence-in-children-with-coeliac-disease-on-a-gluten-free-diet
#19
Reena Jain, Praveen Kumar, Seema Kapoor, Srikanta Basu, Avinash Lomash, Shivani Rohatgi
This study aimed to determine the utility of coeliac serology for monitoring dietary adherence in coeliac disease. Serum anti-tTg IgA and anti-DGP IgG levels of 42 newly diagnosed patients were measured at diagnosis and at intervals of three, six and 12 months after starting a gluten-free diet. Both anti-tTg and anti-DGP antibodies decreased in all patients. The decline in the former was significantly greater at 3-12 months throughout, while in the latter the decline was seen only at three months but not subsequently...
March 14, 2019: Tropical Doctor
https://read.qxmd.com/read/30871416/hepatitis-a-infection-related-haemophagocytic-syndrome-a-case-report-and-systematic-review
#20
Bipadabhanjan Mallick, Philip Daniel, Usha Dutta
Haemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome of excessive inflammation and tissue destruction owing to abnormal immune activation. We report an unusual case of haemophagocytosis associated with hepatitis A virus (HAV) infection in a 21-year-old man. This was further complicated by haemolysis secondary to G-6-PD deficiency and fungal sepsis. Our patient was treated successfully with intravenous immunoglobulin (IVIg) and supportive care. A systematic review of all reported cases of HAV associated haemophagocytosis is presented...
March 14, 2019: Tropical Doctor
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