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Nobuaki Kobayashi, Kuniya Asai, Masafumi Tsurumi, Yusaku Shibata, Hirotake Okazaki, Akihiro Shirakabe, Hiroki Goda, Saori Uchiyama, Kenichi Tani, Masamichi Takano, Wataru Shimizu
OBJECTIVES: We aimed to examine the relations of very high levels of serum uric acid (sUA) with features of culprit lesion plaque morphology determined by optical coherence tomography (OCT) and adverse clinical outcomes in patients with acute coronary syndrome (ACS). METHODS: We retrospectively compared ACS patients according to sUA levels of > 8.0 mg/dL (n = 169), 7.1-8.0 mg/dL (n = 163), 6.1-7.0 mg/dL (n = 259), and ≤6.0 mg/dL (n = 717). Angiography and OCT findings were analyzed in patients with preintervention OCT and the 4 sUA groups (> 8...
February 13, 2019: Cardiology
Sai Lv, Bright E Ohene, Yujie Zhou
No abstract text is available yet for this article.
February 13, 2019: Cardiology
Panpan Feng, Yi Huang, Sihang Wang, Guiquan Yu, Ge Li, Han Lei, Shu Qin, Wei Huang
The aims of this study were to investigate the association between different obesity indices and left ventricular mass (LVM) and to develop interventions for obese hypertensive patients to delay the progression of left ventricular hypertrophy (LVH). The association between the visceral adiposity index (VAI) and LVM was explored using multiple regression analysis in all subjects (n = 1,035), the subgroups of patients aged < 65 (n = 713) and ≥65 years (n = 322), and perimenopausal women (n = 319). The VAI was the only obesity index associated with LVH (OR = 1...
February 6, 2019: Cardiology
Eric M Hecht, Kristopher L Arheart, David J Lee, Charles H Hennekens, WayWay M Hlaing
The interrelationships between cadmium biomarker levels, smoking, and myocardial infarction and stroke have been established. In this cross-sectional analysis, we explored the interrelationships of blood cadmium levels, smoking, and angina. We analyzed the National Health and Nutrition Examination Survey (NHANES, 2003-2014) accounting for the multi-staged complex sampling design. Participants 40-79 years of age with blood cadmium levels but without a history of myocardial infarction and/or stroke were included (n = 14,832)...
January 30, 2019: Cardiology
William C Roberts, Sarah Haque, Shelley A Hall
OBJECTIVE: Although several studies have described the effects of adriamycin on the heart, electrocardiographic total 12-lead QRS voltage (distance in millimeters from the peak of the R wave to the nadir of either the Q or S wave, whichever was deeper, with 10 mm [1 mV] being standard) both before and after orthotopic heart transplantation (OHT) has not been reported. This study describes the total 12-lead QRS voltage in 8 patients studied at Baylor University Medical Center at Dallas, from 1994 to June 2018, who underwent OHT for severe heart failure caused by anthracycline-induced cardiomyopathy...
January 16, 2019: Cardiology
Eliezer Joseph Tassone, Cesare Tripolino, Gaetano Morabito, Placido Grillo, Bindo Missiroli
Coronary calcification is a hard challenge for the interventional cardiologist, as it is associated with incomplete stent expansion and frequently stent failure. In recent years, innovative techniques, such as rotational atherectomy, have been developed to treat coronary calcification. However, these are burdened with an increased procedural risk. We report the case of a 60-year-old Caucasian man treated 1 month before at another center with primary coronary angioplasty and stenting of the ramus intermedius for coronary syndrome...
January 10, 2019: Cardiology
Deepa Selvi Rani, Pratibha Nallari, Jhansi Rani, Sheikh Nizamuddin, Thulasamma Seelamneni, Calambur Narasimhan, Kumarasamy Thangaraj
BACKGROUND: Myosin is a hexameric contractile protein composed of 2 heavy chains associated with 4 light chains of 2 distinct classes - 2 regulatory light chains (MYL2) and 2 essential light chains (MYL3). The myosin light chains stabilize the long alpha helical neck of the myosin head and regulate the myosin ATPase activities. OBJECTIVES: Mutations in MYL2 and MYL3 are reported to be associated with cardiomyopathies. However, there is no study available on these genes in Indian cardiomyopathies, and therefore we planned to study them...
January 3, 2019: Cardiology
Malena P Pantou, Polyxeni Gourzi, Aggeliki Gkouziouta, Dimitrios Tsiapras, Christianna Zygouri, Pantelis Constantoulakis, Stamatis Adamopoulos, Dimitrios Degiannis
OBJECTIVE: We present the genotypic and phenotypic characterization of a family displaying dilated cardiomyopathy (DCM). METHODS: The proband and his relatives underwent full cardiological assessment. Genetic analysis of the proband was performed with the use of next-generation sequencing technology. RESULTS: In this study, we present 6 members of a family carrying the RBM20 mutation NM_001134363.2:c.1900C>T. The proband was initially diagnosed with DCM at the age of 18 years and received an implantable cardioverter defibrillator (ICD) due to ventricular arrhythmias...
December 17, 2018: Cardiology
Asim Katbeh, Tomas Ondrus, Emanuele Barbato, Maurizio Galderisi, Bruno Trimarco, Guy Van Camp, Marc Vanderheyden, Martin Penicka
Patients with severe aortic stenosis (AS) show progressive fibrotic changes in the myocardium, which may impair cardiac function and patient outcomes even after successful aortic valve replacement. Detection of patients who need an early operation remains a diagnostic challenge as myocardial functional changes may be subtle. In recent years, speckle tracking echocardiography (STE) and cardiac magnetic resonance mapping have been shown to provide complementary information for the assessment of left ventricular mechanics and identification of subtle damage by focal or diffuse myocardial fibrosis, respectively...
December 5, 2018: Cardiology
Zubair Shah, Venkat Vuddanda, Aniket S Rali, Hema Pamulapati, Reza Masoomi, Kamal Gupta
AIM: The aim of this study is to report recent trends in the performance of endomyocardial biopsy (EMB) and its in-hospital complications (and their predictors) in the United States (US). METHOD: We analyzed Nationwide Inpatient Sample (NIS) database from years 2007 through 2014 to identify patients who underwent EMB. Once identified, the patients were subdivided into those with no history of heart transplant (HT) (cohort 1) and those with history of HT (cohort 2)...
December 5, 2018: Cardiology
Jubo Jiang, Xianbao Liu, Yuxin He, Qiyuan Xu, Qifeng Zhu, Sanjay Jaiswal, Lihan Wang, Po Hu, Feng Gao, Yinghao Sun, Chunhui Liu, Xiaoping Lin, Jie Liang, Kaida Ren, Jian Apos An Wang
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is a recent and an effective treatment option for high- or extreme-surgical-risk patients with symptomatic severe aortic stenosis. However, pure severe native aortic valve regurgitation (NAVR) without aortic stenosis remains a contraindication to TAVR. The aim of our systemic review analysis was to evaluate TAVR in patients with pure NAVR. METHODS: We searched the published articles in the PubMed and Web of Science databases (2002-2017) using the Boolean operators for studies of NAVR patients undergoing TAVR...
December 5, 2018: Cardiology
Yanfeng Jiang, Zehan Fan, Yingzhe Wang, Chen Suo, Mei Cui, Ziyu Yuan, Weizhong Tian, Min Fan, Dekun Zhang, Xiaofeng Wang, Li Jin, Weimin Ye, Shuyuan Li, Xingdong Chen
OBJECTIVES: Loss of bone mass may affect the progression of atherosclerosis. We investigated the relationship between low bone mineral density (BMD) and subclinical atherosclerosis in rural China. METHODS: In total, 333 men and 421 postmenopausal women aged 55-65 years were enrolled. BMD was measured in the lumbar spine, femoral neck, and total hip using dual-energy X-ray absorptiometry. Subclinical atherosclerosis was defined as increased carotid artery intima-media thickness (CIMT ≥0...
November 13, 2018: Cardiology
Gaetano Morabito, Cesare Tripolino, Eliezer Joseph Tassone, Placido Grillo, Bindo Missiroli
We report the case of a stent under-expansion due to heavily calcified plaque treated with the shockwave lithoplasty system. A 77-year-old woman underwent coronary angiography, and intravascular ultrasound revealed stent under-expansion due to calcified plaque. Shockwave lithoplasty balloon was used to disrupt calcium deposits around the stent, thereby allowing a correct stent expansion with an excellent angiographic and intravascular ultrasound result.
November 8, 2018: Cardiology
Constantine N Antonopoulos, Christos D Liapis
No abstract text is available yet for this article.
2018: Cardiology
Kanchi Patel, Mohammad A Zafar, Bulat A Ziganshin, John A Elefteriades
OBJECTIVES: In the course of extensive clinical aortic surgery, we noticed that the aorta was quite thick and fibrotic in diabetic patients. We thought the diabetic aortic aorta might be inimitable to aortic dissection. On this basis, we set out to review information in the literature regarding aortic growth and dissection in diabetic patients. METHODS: We used a 2-step search approach to the available literature on diabetes and aneurysm. Firstly, databases including PubMed, Cochrane, Embase and TRIP were searched...
2018: Cardiology
Katerina Fountoulaki, Sotirios Tsiodras, Eftychia Polyzogopoulou, Christophoros Olympios, John Parissis
Influenza and pneumococcal infections have been suggested to be potential risk factors for causing adverse cardiovascular events, especially in high-risk patients. Vaccination against respiratory infections in patients with established cardiovascular disease (CVD) could serve as a potential cost-effective intervention to improve their clinical outcomes and cardiac societies have encouraged it. Previous studies have shown that influenza vaccination reduce mortality, acute coronary syndromes and hospitalization in patients with coronary heart disease (CHD) and/or heart failure (HF)...
2018: Cardiology
Yan Gao, Yan Qiu, Jihua Wu, Wei Diao, Haibo Zhang, Siming Wang, Zhiqiang Du, Jun Dong, Mingqiang Zhang, Lixin Jiang
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising target for lowering plasma low-density lipoprotein cholesterol and preventing cardiovascular (CV) disease. Whether plasma PCSK9 measured during the acute phase predicts recurrent CV events in patients with acute myocardial infarction (AMI) remains unresolved. METHODS AND RESULTS: Plasma PCSK9 levels were measured in 1,646 patients with AMI from the China PEACE-Prospective AMI Study at the acute phase...
2018: Cardiology
George Lazaros, Maria I Drakopoulou, Dimitris Tousoulis
No abstract text is available yet for this article.
2018: Cardiology
Chris J Kapelios, Maria Bonou, John Barbetseas
No abstract text is available yet for this article.
2018: Cardiology
Efstathios Iliodromitis, Dimitrios Farmakis
No abstract text is available yet for this article.
2018: Cardiology
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