Kamani Dhanushka Liyanarachchi, Dimuthu Tharanga Muthukuda, Udari Apsara Liyanage, Renuka Jayatissa, Lakma Tharindi Subasinghe, Ariyavidana Hareendra Pradeep, Eranga Colombage, Lalana Devi Ranasinghe, Nadun Prabuddha Liyanarachchi, Samantha Ranasinghe, Sarath Lekamwasam, Noel Somasundaram
INTRODUCTION: Regional differences in thyroid hormones are noted, especially during pregnancy. OBJECTIVES: Establish reference values for thyroid function tests for Sri Lankan pregnant women and to determine their comparability with regional data; and determine the prevalence of 2. Thyroid Peroxidase (TPO) antibody positivity and 3. Iodine deficiency among pregnant women with uncomplicated clinical history. METHODS: A cross-sectional study conducted in antenatal clinics of a tertiary care maternity center recruited a minimum of 56 women in each trimester in a multistep approach to derive an "ideal-reference population"; Participants with clinically manifested thyroid disease, followed by subjects with sonographically abnormal thyroids and finally those at high risk for thyroid disease as shown by positive TPO levels and urine iodine deficiency were excluded in sequence...
June 30, 2022: Ceylon Medical Journal