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Journals Scandinavian Journal of Gastro...

Scandinavian Journal of Gastroenterology. Supplement

https://read.qxmd.com/read/15696847/endoscopic-treatment-of-barrett-s-oesophagus
#41
REVIEW
R A Veenendaal, G Griffioen, C B H W Lamers
Barrett's oesophagus develops as a consequence of severe gastro-oesophageal reflux. The importance of Barrett's oesophagus lies in the small risk of developing high-grade dysplasia and subsequent adenocarcinoma. Because of poor treatment results in patients with advanced adenocarcinoma, surveillance of patients with Barrett's oesophagus for the development of dysplasia, although not uncontroversial, is widely practised in the gastroenterological community. The aim of surveillance is to detect adenocarcinoma in an early stadium where surgical cure is possible...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15696846/value-of-magnification-endoscopy-in-current-clinical-practice
#42
REVIEW
M P Schwartz
Ongoing technological developments in endoscopy have led to an ever improving evaluation and management of digestive diseases. The recent development of a new range of high-power magnification, or zoom, endoscopes has boosted interest in this technique, which has become increasingly available to the modern gastroenterologist. Magnification is often used in conjunction with chromoendoscopy in order to improve the detection and diagnosis of neoplastic tissue. Currently, the main clinical indications are the diagnosis of Barrett oesophagus, the colonoscopic surveillance of colonic polyps and the assessment of disease severity or the presence of dysplasia in inflammatory bowel disease...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15696845/children-with-constipation-what-happens-to-them-when-they-grow-up
#43
REVIEW
M A Benninga
Constipation and soiling are common complaints in childhood and often cause distress to the children and their parents. The treatment for these symptoms is oral and sometimes rectal laxatives or behavioural therapy. Until now, there have been few randomized controlled trials to evaluate the efficacy of the different treatment regimens. Moreover, there is a lack of information regarding what happens to these children with constipation when they grow up. A recent long-term follow-up study in The Netherlands showed that 30% of the children followed beyond puberty continued to have severe complaints of constipation such as a low defecation frequency and soiling...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15696844/irritable-bowel-syndrome-in-general-practice-an-overview
#44
REVIEW
A H Oberndorff-Klein Woolthuis, R J M Brummer, N J de Wit, J W M Muris, R W Stockbrügger
BACKGROUND: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is frequently seen in gastroenterological practice. Population-based studies have shown that at any point in time IBS symptoms are present in about 3%-22% of the general Western population. In general practice, half of all new patients have functional disorders and IBS is responsible for about five consultations per week. General practitioners (GPs) manage the majority of IBS patients, but most knowledge (and research) is based on the smaller percentage of patients managed in secondary care...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15696843/clinical-approach-to-chronic-gastrointestinal-ischaemia-from-intestinal-angina-to-the-spectrum-of-chronic-splanchnic-disease
#45
REVIEW
J J Kolkman, P B F Mensink, A S van Petersen, A B Huisman, R H Geelkerken
Stenotic disorders of the splanchnic arteries are not rare, and it is generally assumed that symptoms are rare in patients with a single splanchnic stenosis, and even in patients with multiple-vessel stenoses. Currently, only gastric exercise tonometry aids the diagnostic evaluation, as it indicates actual ischaemia. Patients with stenotic disorders without complaints are referred to as having chronic splanchnic disease (CSD) and those with ischaemic complaints as having chronic splanchnic syndrome (CSS). The classical presentation of CSS, including the triad postprandial pain, weight loss and upper abdominal bruit, is also known as 'intestinal angina'...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15696842/early-experience-in-robot-assisted-laparoscopic-heller-myotomy
#46
JOURNAL ARTICLE
J P Ruurda, H G Gooszen, I A M J Broeders
Heller myotomy for achalasia is routinely performed laparoscopically. This offers patients significant benefits compared to open surgery. Surgeons, however, are limited in their manipulation and visualization during laparoscopic interventions. Robotic telemanipulation systems were introduced with the objective of alleviating these limitations. The purpose of this study was to demonstrate the efficacy and safety of performing a Heller myotomy with the use of a robotic telemanipulation system. Fourteen patients were operated on with the da Vinci robot system...
2004: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/15279018/abstracts-of-papers-presented-at-the-xxxvi-nordic-meeting-of-gastroenterology-the-xxvii-nordic-meeting-of-digestive-endoscopy-the-xv-nordic-meeting-of-gastrointestinal-motility-the-annual-endoscopy-gastroenterology-nurses-s-assistants-meeting-oslo-norway-2
#47
https://read.qxmd.com/read/14743894/acute-idiopathic-pancreatitis-does-it-really-exist-or-is-it-a-myth
#48
REVIEW
S E van Brummelen, N G Venneman, K J van Erpecum, G P VanBerge-Henegouwen
BACKGROUND: Acute pancreatitis is a severe disease with considerable morbidity and mortality. Gallstones and alcohol abuse are the most frequent causes (75% of patients). Other well-known causes are: hyperlipidemia, hypercalcaemia, abdominal surgery and drugs. In 10%-40% of patients however, no cause is identified after initial diagnostic evaluation: acute idiopathic pancreatitis. Identifying a cause in these patients is important, since the recurrence rate is high. METHODS: A systematic review of the current literature was performed to identify possible causes, diagnoses and treatment options of acute idiopathic pancreatitis...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743893/surgical-management-of-acute-necrotizing-pancreatitis-a-13-year-experience-and-a-systematic-review
#49
REVIEW
V B Nieuwenhuijs, M G H Besselink, L P van Minnen, H G Gooszen
BACKGROUND: The course of acute pancreatitis (AP) is unpredictable and can vary from mild to lethal. Mortality varies from low (<2%) in mild cases to high (20%-70%) in the case of infected pancreatic necrosis. Surgical management has not been investigated in well-designed trials. Based on literature review and retrospective results from our institution, recent insights are summarized and recommendations concerning surgical treatment of AP are given. METHODS: Data of patients who underwent necrosectomy for AP in our hospital in the period 1988-2001 were reviewed...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743892/hepatitis-c-2002-guidelines-summary-and-annotations
#50
REVIEW
H Orlent, J M Vrolijk, B J Veldt, S W Schalm
BACKGROUND: The current NIH and French consensus provide physicians with clear guidelines on how to care best for patients with hepatitis C. METHODS: Review and discussion. RESULTS: Confirming the diagnosis and guiding the initial investigations have become straightforward. The standard treatment and its monitoring have been described in many publications. Recommending therapy to patients with moderate fibrosis has been the custom since the 1999 EASL guidelines...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743891/transjugular-intrahepatic-portosystemic-shunt-tips-indications-and-long-term-patency
#51
REVIEW
H R van Buuren, P C J ter Borg
BACKGROUND: Since the introduction of TIPS (the transjugular intrahepatic portosystemic shunt) into clinical practice in 1989, substantial knowledge, partially derived from controlled trials, has become available regarding technical and clinical aspects of the procedure. A number of prospective studies have assessed the long-term patency of radiological shunts, the recognized main technical weakness of the procedure. METHODS: Review of published data regarding the optimal indications and long-term patency of TIPS...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743890/surveillance-for-familial-pancreatic-cancer
#52
REVIEW
W H de Vos tot Nederveen Cappel, M A C Lagendijk, C B H W Lamers, H Morreau, H F A Vasen
BACKGROUND: It is estimated that between 5% and 10% of pancreatic cancer (PC) cases are due to hereditary factors. METHODS: Review of the literature. RESULTS: In families with clustering of PC, germline mutations in specific genes might be responsible for the disease. It is suggested that PC progresses from precursor lesions, the pancreatic intraepithelial neoplasias (PanINs). Several key genetic alterations in oncogenes (K-ras, Her2/neu) and tumour suppressor genes (p16, p53, SMAD4) occur in the progression from PanIN lesions towards PC...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743889/role-of-cyclooxygenase-2-in-the-development-and-treatment-of-oesophageal-adenocarcinoma
#53
REVIEW
C J Buskens, A Ristimäki, G J A Offerhaus, D J Richel, J J B van Lanschot
BACKGROUND: Various studies suggest that aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) are promising anticancer agents. Epidemiological studies have found that long-term use of NSAIDs is associated with a reduced incidence of colorectal, gastric and oesophageal cancers, while experimental and clinical studies have demonstrated that treatment with NSAIDs causes a statistically significant reduction in both the number and the size of polyps in familial adenomatous polyposis (FAP) patients...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743888/new-developments-in-systemic-chemotherapy-in-advanced-colorectal-cancer
#54
REVIEW
A Cats
BACKGROUND: The majority of patients with newly diagnosed colorectal cancer who present with concurrent metastases are considered to be incurable from the disease. For their treatment, these patients depend on systemic anticancer therapy and supportive care. METHODS: This article reviews recent developments in systemic treatment of disseminated colorectal cancer. RESULTS: Until recently, the fluoropyrimidines were the only cytotoxic drugs available, but during recent years three other classes of active conventional cytotoxic drugs and a new class of target-directed drugs have become available...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743887/screening-for-colorectal-cancer-medical-and-economic-aspects
#55
REVIEW
S Sanduleanu, R W Stockbrügger
BACKGROUND: Colorectal cancer (CRC) is the second commonest cause of cancer death in the Western world. In The Netherlands, CRC causes about 4400 deaths per year, and its diagnosis and treatment make up for a large share of health-care costs. METHODS: Review and discussioN. RESULTS: Experts in the field presently assume that screening for CRC and its precursor lesions, colorectal adenomas (CRAs), could prevent death from colorectal neoplasia by more than 80%...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743886/safety-of-thiopurines-in-the-treatment-of-inflammatory-bowel-disease
#56
REVIEW
D J de Jong, L J J Derijks, A H J Naber, P M Hooymans, C J J Mulder
BACKGROUND: Thiopurines have proven efficacy in inflammatory bowel disease. However, concerns regarding toxicity have limited the use of these agents as first line of medical therapy. METHODS: Review of the literature regarding metabolism, efficacy and side effects. RESULTS: In clinical trials, up to 15% of patients discontinued 6-mercaptopurine or its pro-drug azathioprine prematurely due to adverse events. These events may be divided into dose-independent idiosyncratic reactions and dose-related, pharmacologically explainable toxicity...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743885/ibd-and-genetics-new-developments
#57
REVIEW
L E Oostenbrug, H M van Dullemen, G J te Meerman, P L M Jansen
BACKGROUND: Inflammatory bowel disease (IBD) is a complex disorder with an aetiology that is only partly understood. Apart from environmental factors, inheritance contributes to IBD. REVIEW: Family studies show an increased risk among family members of a patient with IBD, particularly among first-degree relatives. In twin studies, concordance for disease type and localization is observed. In genetically isolated groups there is a higher prevalence of IBD. For instance...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743884/haemostasis-in-inflammatory-bowel-diseases-clinical-relevance
#58
REVIEW
A A van Bodegraven
BACKGROUND: In inflammatory bowel disease (IBD), many alterations of haemostasis have been reported. Furthermore. IBD is associated with thromboembolic disease. METHODS: Literature on new insights into the physiology of haemostasis. the interaction between haemostasis and inflammation, plasmatic and mucosal changes in haemostasis in IBD, and haemostasis-interfering therapy in patients with IBD are reviewed. RESULTS: Haemostasis is a vascular-bed-specific, locally regulated, physiological phenomenon aimed at the maintenance of fluidity of blood, and not a simple cascade-shaped chain of reactions...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743883/dyspepsia-management-in-primary-care
#59
REVIEW
J C Thijs, N L A Arents, A A van Zwet, J H Kleibeuker
BACKGROUND: Dyspepsia is common in western society. Prompt endoscopy is imperative in all patients with sinister symptoms or if symptoms first appear after the age of 50-55 years, but the optimal management of younger patients with uncomplicated dyspepsia is still open to debate. METHODS: The literature on the management of uncomplicated dyspepsia is reviewed and a personal view is presented. RESULTS: Strategies based on non-invasive detection of Helicobacter pylori are probably the most cost-effective...
2003: Scandinavian Journal of Gastroenterology. Supplement
https://read.qxmd.com/read/14743882/pathophysiological-characteristics-of-long-and-short-segment-barrett-s-oesophagus
#60
REVIEW
P Zentilin, S Reglioni, V Savarino
BACKGROUND: Depending on the length of the segment of columnar epithelium in the distal oesophagus, Barrett's oesophagus can be divided into long-segment and short-segment Barrett's oesophagus. This article describes the pathophysiological characteristics of both forms of Barrett's oesophagus. METHODS: Review of the literature. RESULTS: Although there is some disagreement, ours and most other studies suggest that long-segment columnar-lined oesophagus is causally linked to chronic gastro-oesophageal reflux and that this from of Barrett's oesophagus is characterized by lower oesophageal sphincter tone, reduced oesophageal contractility and increased acid reflux...
2003: Scandinavian Journal of Gastroenterology. Supplement
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