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Arquivos Brasileiros de Cardiologia

Jessica Vanina Ortiz, Bruna Valessa Moutinho Pereira, Katia do Nascimento Couceiro, Monica Regina Hosannah da Silva E Silva, Susan Smith Doria, Paula Rita Leite da Silva, Edson da Fonseca de Lira, Maria das Graças Vale Barbosa Guerra, Jorge Augusto de Oliveira Guerra, João Marcos Bemfica Barbosa Ferreira
BACKGROUND: In the past two decades, a new epidemiological profile of Chagas' disease (CD) has been registered in the Brazilian Amazon where oral transmission has been indicated as responsible for the increase of acute cases. In the Amazonas state, five outbreaks of acute CD have been registered since 2004. The cardiac manifestations in these cases may be characterized by diffuse myocarditis, with alteration in the electrocardiogram (ECG) and transthoracic echocardiogram (TTE). OBJECTIVE: To perform a cardiac evaluation in autochthonous patients in the acute phase and at least one year after submitted to treatment for acute CD and evaluate the demographic variables associated with the presence of cardiac alterations...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Davi Dantas Muniz, Kamile Santos Siqueira, Cristina Toledo Cornell, Miguel Morita Fernandes-Silva, Pascoal Torres Muniz, Odilson Marcos Silvestre
BACKGROUND: Ideal Cardiovascular (CV) Health is characterized by four ideal lifestyle parameters and absence of cardiovascular risk factors. The prevalence of ideal CV health in the Amazon Basin and the influence of job strain on CV health in this setting are uncertain. OBJECTIVE: To evaluate the prevalence of ideal CV health and its relationship with job strain in a secluded area from a developing country. METHODS: Job strain was evaluated in 478 employees from an university in the Amazon Basin by a questionnaire that classified participants as passive, active, low or high strain, according to the demand-control model...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Ana Luiza Lima Sousa, Sandro Rodrigues Batista, Andrea Cristina Sousa, Jade Alves S Pacheco, Priscila Valverde de Oliveira Vitorino, Valéria Pagotto
BACKGROUND: The diagnosis, treatment and control of arterial hypertension are fundamental for a reduction in cardiovascular outcomes, especially in the elderly. In Brazil, there are few studies that specifically identified these rates in the elderly population. OBJECTIVE: To verify rates of prevalence, treatment and control of hypertension in elderly people living in the urban area of a Brazilian capital city. METHODS: A cross-sectional, population-based, randomized, cluster-based study with 912 non-institutionalized elderly individuals (≥ 60 years), living in urban areas in the city of Goiania, Midwest Brazil...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Michaela Eickemberg, Leila Denise Alves Ferreira Amorim, Maria da Conceição Chagas de Almeida, Estela Maria Leão de Aquino, Maria de Jesus Mendes da Fonseca, Itamar de Souza Santos, Dora Chor, Maria de Fátima Sander Diniz, Sandhi Maria Barreto, Sheila Maria Alvim de Matos
BACKGROUND: Abdominal adiposity is a risk factor for cardiovascular disease. OBJECTIVE: To determine the magnitude of the association between abdominal adiposity, according to five different indicators, and the carotid intima-media thickness (CIMT). METHODS: Data from 8,449 participants aged 35 to 74 years from the ELSA-Brazil study were used. The effect of waist circumference (WC), waist-to-hip ratio (WHR), conicity index (C index), lipid accumulation product (LAP) and visceral adiposity index (VAI) on CIMT were evaluated...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Alberto Takeshi Kiyose, Erica Aranha Suzumura, Lígia Laranjeira, Anna Maria Buehler, José Amalth Espírito Santo, Otavio Berwanger, Antonio Carlos de Camargo Carvalho, Angelo Amato de Paola, Valdir Ambrósio Moises, Alexandre Biasi Cavalcanti
BACKGROUND: The choice of a mechanical (MP) or biological prosthesis (BP) for patients with valvular heart disease undergoing replacement is still not a consensus. OBJECTIVE: We aimed to determine the clinical outcomes of MP or BP placement in those patients. METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) that compared biological prostheses and mechanical prostheses in patients with valvular heart diseases and assessed the outcomes...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Dalton Valentim Vassallo, Maylla Ronacher Simões, Karina Giuberti, Bruna Fernandes Azevedo, Rogerio Faustino Ribeiro Junior, Mercedes Salaices, Ivanita Stefanon
BACKGROUND: Mercury's deleterious effects are associated with increased cardiovascular risk. OBJECTIVE: To determine whether chronic exposure to inorganic mercury increases the activity of angiotensin-converting enzyme and its relationship with oxidative stress in several organs and tissues. METHODS: We studied male Wistar and spontaneously hypertensive rats (SHR) (3-month-old) exposed or not to HgCl2 for 30 days. At the end of treatment, we investigated the following: changes in body weight, hemodynamic parameters, angiotensin-converting enzyme (ACE) activity and oxidative stress in the heart, aorta, lung, brain and kidney in hypertensive compared to normotensive animals...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Leandro Teixeira de Castro, Itamar de Souza Santos, Alessandra C Goulart, Alexandre da Costa Pereira, Henrique Lane Staniak, Marcio Sommer Bittencourt, Paulo Andrade Lotufo, Isabela Martins Bensenor
BACKGROUND: High-sensitivity cardiac troponin I (hs-cTnI) has played an important role in the risk stratification of patients during the in-hospital phase of acute coronary syndrome (ACS), but few studies have determined its role as a long-term prognostic marker in the outpatient setting. OBJECTIVE: To investigate the association between levels of hs-cTnI measured in the subacute phase after an ACS event and long-term prognosis in a highly admixed population. METHODS: We measured levels of hs-cTnI in 525 patients 25 to 90 days after admission for an ACS event; these patients were then divided into tertiles according to hs-cTnI levels and followed for up to 7 years...
January 7, 2019: Arquivos Brasileiros de Cardiologia
Roya Naderi, Gisou Mohaddes, Mustafa Mohammadi, Alireza Alihemmati, Amirmahdi Khamaneh, Rafighe Ghyasi, Rana Ghaznavi
BACKGROUND: Diabetes mellitus (DM) is one of the major risk factors for cardiovascular disease, leading to endothelial dysfunction and angiogenesis impairment . MiR-126 and miR-210 support angiogenic response in endothelial cells. OBJECTIVE: The present study sought to explore the effect of garlic and voluntary exercise, alone or together, on miR-126 and miR-210 expressions and cardiac angiogenesis in rats with type 1 diabetes. METHODS: Male Wistar rats were divided into five groups (n = 7): Control, Diabetes, Diabetes+Garlic, Diabetes+Exercise, and Diabetes+Garlic+Exercise...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Laura Beatriz M Maifrino, Nathalia E A de Lima, Mara R Marques, Clever G Cardoso, Lidiane B de Souza, Tabata de Carvalho Tomé, Hananiah Tardivo Quintana, Flavia de Oliveira, Beatriz da Costa Aguiar Alves Reis, Fernando Luiz Affonso Fonseca
BACKGROUND: In menopause, there is greater cellular exposure to oxidative stress, related to the decreased antioxidative effects of estrogen. These metabolic changes favor the progression of cardiovascular diseases, such as atherosclerosis. Abnormal function of the aorta - the most important artery - is associated with many cardiovascular diseases. Collagen, especially types I and III, is one of the most important aortic wall components and it can be affected by many factors, including menopause...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Edgard Freitas Quintella, Esmeralci Ferreira, Vitor Manuel Pereira Azevedo, Denizar V Araujo, Fernando Mendes Sant'Anna, Bernardo Amorim, Denilson Campos de Albuquerque
BACKGROUND: In multivessel disease patients with moderate stenosis, fractional flow reserve (FFR) allows the analysis of the lesions and guides treatment, and could contribute to the cost-effectiveness (CE) of non-pharmacological stents (NPS). OBJECTIVES: To evaluate CE and clinical impact of FFR-guided versus angiography-guided angioplasty (ANGIO) in multivessel patients using NPS. METHODS: Multivessel disease patients were prospectively randomized to FFR or ANGIO groups during a 5 year-period and followed for < 12 months...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Nathalia Pereira Vizentin, Paula Mendonça Santos Cardoso, Camila Aparecida Gomes Maia, Isabela Perez Alves, Gabriel Lunardi Aranha, Denise Tavares Giannini
BACKGROUND: Early exposure to obesity favors greater risks of cardiovascular factors such as dyslipidemia. OBJECTIVES: To establish the prevalence of dyslipidemia, and to evaluate its association with nutritional status of the adolescents attended at the ambulatory of the Adolescent Health Studies Center of the University Hospital Pedro Ernesto. METHODS: This is a cross-sectional, observational study, the sample of which was of convenience, consisting of adolescents from 12 to 18 years old of both genders...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Asim Enhos, Kahraman Cosansu, Mustafa Ahmet Huyut, Fahrettin Turna, Erdem Karacop, Nijad Bakshaliyev, Aydin Nadir, Ramazan Ozdemir, Mahmut Uluganyan
BACKGROUND: Assessing the monocyte to high-density lipoprotein ratio (MHR) is a new tool for predicting inflamation, which plays a major role in atherosclerosis. Myocardial bridge (MB) is thought to be a benign condition with development of atherosclerosis, particularly at the proximal segment of the brigde. OBJECTIVE: To evaluate the relationhip between MHR and the presence of MB. METHODS: We consecutively scanned patients referred for coronary angiography between January 2013- December 2016, and a total of 160 patients who had a MB and normal coronary artery were enrolled in the study...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Shahnaz Shekarforoush, Mohammad Reza Naghii
BACKGROUND: Whole body vibration training (WBV) is a new training program, which is safe and effective. It can be followed by the public. However, data on the safety and efficacy of vibration on myocardial ischemia reperfusion (IR) injury are lacking. OBJECTIVE: To examine the effect of WBV on the tolerance of the myocardium to acute IR injury in an experimental rat model. METHODS: Twenty-four male Wistar rats were divided into control and vibration groups...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Mustafa Umut Somuncu, Ali Riza Demir, Seda Tukenmez Karakurt, Huseyin Karakurt, Turgut Karabag
BACKGROUND: A subset of patients who take antiplatelet therapy continues to have recurrent cardiovascular events which may be due to antiplatelet resistance. The effect of low response to aspirin or clopidogrel on prognosis was examined in different patient populations. OBJECTIVE: We aimed to investigate the prevalence of poor response to dual antiplatelet therapy and its relationship with major adverse cardiovascular events (MACE) in young patients with ST-elevation myocardial infarction (STEMI)...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Tufi Dippe, Cláudio Leinig Pereira da Cunha, Rodrigo Julio Cerci, Arnaldo Lafitte Stier, João Vicente Vítola
BACKGROUND: Obesity is associated with an increased risk of type 2 diabetes mellitus (DM), ischemic heart disease (IHD) and cardiovascular mortality. Several studies have demonstrated the diagnostic and prognostic value of single photon computed tomography-myocardial perfusion scintigraphy (SPECT-MPI) in the evaluation of patients with suspected IHD, including in obese population. Data on clinical risk factors and their association with abnormal myocardial perfusion in obese patients are scarce in the Brazilian population...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Fatemeh Ramezani-Aliakbari, Mohammad Badavi, Mahin Dianat, Seyed Ali Mard, Akram Ahangarpour
BACKGROUND: Trimetazidine (TMZ) is an anti-ischemic drug. In spite of its protective effects on cardiovascular system, there is no scientific study on the usefulness of TMZ treatment for prolonged QT interval and cardiac hypertrophy induced by diabetes. OBJECTIVES: To evaluate the effects of TMZ on QT interval prolongation and cardiac hypertrophy in the diabetic rats. METHODS: Twenty-four male Sprague-Dawley rats (200-250 g) were randomly assigned into three groups (n = 8) by simple random sampling method...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Tianshu-Chu, Congrong-Gao, Zhiwei-Zhao, Fei-Ling, Ayu-Sun, Yuanbiao-Zheng, Jing-Cao, Jianjun Ge
BACKGROUND: Vein graft restenosis has an adverse impact on bridge vessel circulation and patient prognosis after coronary artery bypass grafting. OBJECTIVES: We used the extravascular supporter α-cyanoacrylate (α-CA), the local application rapamycin/sirolimus (RPM), and a combination of the two (α-CA-RPM) in rat models of autogenous vein graft to stimulate vein graft change. The aim of our study was to observe the effect of α-CA, RPM, and α-CA-RPM on vein hyperplasia...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Rafaella Zulianello Dos Santos, Gabriela Lima Melo Ghisi, Christiani Decker Batista Bonin, Gabriela Chaves, Clarissa Machado Haase, Raquel Rodrigues Britto, Magnus Benetti
BACKGROUND: The Coronary Artery Disease Education Questionnaire (CADE-Q), an instrument aimed at assessing patients' knowledge about coronary artery disease (CAD), was originally developed and psychometrically validated in Brazil. It was later translated, cross-culturally adapted, and validated to English. Although both versions demonstrated good reliability and validity, new studies in the area have pointed out the need of implementing the CADE-Q with other components of cardiac rehabilitation (CR) programs, such as psychologic factors, which had not been considered in previous version and were added in the subsequent, adapted version...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Mehmet Eyuboglu, Bahri Akdeniz
BACKGROUND: Fragmented QRS (fQRS) is a sign of adverse cardiovascular events in various cardiovascular diseases. It is also associated with increased blood pressure and non-dipping in hypertensive patients. However, no study has investigated the importance of fQRS in prehypertensive patients. OBJECTIVES: The aim of our study is to investigate the relationship between fQRS and non-dipper status in prehypertensive patients. METHODS: Two hundred and sixteen eligible, newly diagnosed prehypertensive patients who underwent 24-hour ambulatory blood pressure monitoring (ABPM) for further evaluation of blood pressure between June 2015 and July 2016 were included into the study...
December 17, 2018: Arquivos Brasileiros de Cardiologia
Gabriel Dotta, Francisco Antonio Helfenstein Fonseca, Maria Cristina de Oliveira Izar, Marco Tulio de Souza, Flavio Tocci Moreira, Luiz Fernando Muniz Pinheiro, Adriano Henrique Pereira Barbosa, Adriano Mendes Caixeta, Rui Manoel Santos Póvoa, Antônio Carlos Carvalho, Henrique Tria Bianco
BACKGROUND: Patients with ST-elevation acute myocardial infarction attending primary care centers, treated with pharmaco-invasive strategy, are submitted to coronary angiography within 2-24 hours of fibrinolytic treatment. In this context, the knowledge about biomarkers of reperfusion, such as 50% ST-segment resolution is crucial. OBJECTIVE: To evaluate the performance of QT interval dispersion in addition to other classical criteria, as an early marker of reperfusion after thrombolytic therapy...
December 17, 2018: Arquivos Brasileiros de Cardiologia
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