Moriei Shibuya, Minobu Shichiji, Miki Ikeda, Kaori Kodama, Takuya Miyabayashi, Ryo Sato, Yukimune Okubo, Wakaba Endo, Takehiko Inui, Noriko Togashi, Mika Nagao, Kaname Sato, Takatoshi Sato, Masato Kanzaki, Osamu Segawa, Kenta Masui, Keiko Ishigaki, Kazuhiro Haginoya
Juvenile myasthenia gravis (JMG) exhibits a more favorable response to glucocorticoids and has a better prognosis than adult myasthenia gravis. However, no established treatment exists for refractory JMG. Although thymectomy has been performed in several patients with refractory systemic JMG, there are few detailed clinical descriptions of patients who underwent thymectomy. Here, we present the case of a 10-year-old boy with refractory systemic JMG who was successfully treated with thymectomy. The patient developed symptoms, including dysphagia, malaise, diurnal ptosis, and weakness in the trunk muscles, and he was diagnosed with generalized JMG...
January 23, 2024: Tohoku Journal of Experimental Medicine