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Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques

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https://read.qxmd.com/read/31097049/-the-other-side-of-the-coin-hemorrhagic-stroke-in-congenital-hypofibrinogenemia
#1
Amado Jimenez-Ruiz, Alejandro Gutierrez-Castillo, Jose Luis Ruiz-Sandoval
No abstract text is available yet for this article.
May 17, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31088590/venous-sinus-stenosis-causing-isolated-pulsatile-tinnitus
#2
Miguel Quintas-Neves, Eduardo Freitas, José Manuel Amorim, Jaime Rocha, João Pinho
No abstract text is available yet for this article.
May 15, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31060643/facial-diplegia-in-neuroinvasive-west-nile-virus-infection
#3
Tommy L H Chan, Adrian Budhram
No abstract text is available yet for this article.
May 7, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31057140/infantile-onset-multisystem-neurologic-endocrine-and-pancreatic-disease-case-and-review
#4
Christine Le, Asuri N Prasad, C Anthony Rupar, Derek Debicki, Andrea Andrade, Chitra Prasad
We report three brothers born to consanguineous parents of Syrian descent, with a homozygous novel c.324G>A (p.W108*) mutation in PTRH2 that encodes peptidyl-tRNA hydrolase 2, causing infantile-onset multisystem neurologic, endocrine, and pancreatic disease (IMNEPD). We describe the core clinical features of postnatal microcephaly, motor and language delay with regression, ataxia, and hearing loss. Additional features include epileptic seizures, pancreatic insufficiency, and peripheral neuropathy. Clinical phenotyping enabled a targeted approach to the investigation and identification of a novel homozygous nonsense mutation in PTRH2, c...
May 6, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31057136/anti-cv2-associated-paraneoplastic-hemichorea-secondary-to-diffuse-large-b-cell-lymphoma
#5
Stephanie Nevison, Philippe Rizek
No abstract text is available yet for this article.
May 6, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31046861/consultation-and-surgical-wait-times-in-cervical-spondylotic-myelopathy
#6
Babak Sharifi, Greg McIntosh, Charles Fisher, W Bradley Jacobs, Michael Johnson, Christopher S Bailey, Sean Christie, Raphaële Charest-Morin, Jérome Paquet, Andrew Nataraj, David Cadotte, Neil Manson, Hamilton Hall, Kenneth C Thomas, Y Raja Rampersaud, Nicolas Dea
BACKGROUND: Cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord impairment. In a public healthcare system, wait times to see spine specialists and eventually access surgical treatment for CSM can be substantial. The goals of this study were to determine consultation wait times (CWT) and surgical wait times (SWT), and identify predictors of wait time length. METHODS: Consecutive patients enrolled in the Canadian Spine Outcomes and Research Network (CSORN) prospective and observational CSM study from March 2015 to July 2017 were included...
May 3, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31030687/reflex-seizures-in-a-patient-with-cdkl5-deficiency-disorder
#7
Tyler Peikes, Jessica N Hartley, Aizeddin A Mhanni, Cheryl R Greenberg, Juan Pablo Appendino
No abstract text is available yet for this article.
April 29, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31030685/continuous-electroencephalography-monitoring-for-critically-ill-neonates-a-canadian-perspective
#8
Sarah Grace Buttle, Erick Sell, Richard Webster, Melanie Varin, Brigitte Lemyre, Cecil Hahn, Daniela Pohl
BACKGROUND: Continuous EEG monitoring, in the form of amplitude-integrated (aEEG) or conventional EEG (cEEG), is used in the neonatal intensive care unit (NICU) to detect subclinical central nervous system pathologies, inform management, and prognosticate neurodevelopmental outcomes. To learn more about provider attitudes and current practices in Canada, we evaluated neurologist and neonatologist opinions regarding NICU EEG monitoring. METHODS: A 15-item electronic questionnaire was distributed to 114 pediatric neurologists and 176 neonatologists working across 25 sites...
April 29, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31030678/a-preliminary-analysis-of-a-home-based-stroke-rehabilitation-program-in-windsor-ontario
#9
Jennifer Voth, Jason Petro, Michael Mallender, Sonja Bridgen, Sara Mannan, Marla Jackson, Nathania R Liem
Community stroke rehabilitation (CSR) is an effective program for survivors to recover at home supported by a multidisciplinary team. A home-based, specialized CSR program was delivered in Windsor, Ontario, to stroke patients who faced barriers to accessing outpatient services following inpatient rehabilitation. Preliminary results show program patients made significant functional improvements from baseline to program discharge. A subgroup analysis revealed that, after adjusting for age and resource intensity, moderate to severe stroke patients made greater functional gains compared to mild stroke patients...
April 29, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31030675/white-matter-damage-in-the-semantic-variant-of-primary-progressive-aphasia
#10
Louis-Olivier Bouchard, Maximiliano A Wilson, Robert Laforce, Simon Duchesne
BACKGROUND: The semantic variant of primary progressive aphasia (svPPA) is a form of dementia, mainly featuring language impairment, for which the extent of white matter (WM) damage is less described than its associated grey matter (GM) atrophy. Our study aimed to characterise the extent of this damage using a sensitive and unbiased approach. METHODS: We conducted a between-group study comparing 10 patients with a clinical diagnosis of svPPA, recruited between 2011 and 2014 at a tertiary reference centre, with 9 cognitively healthy, age-matched controls...
April 29, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31010448/meningeal-myelomatosis-illustrated-on-flair-post-contrasted-images
#11
Natalia Silva, Marcia Delamain, Gislaine Duarte, Fabiano Reis
No abstract text is available yet for this article.
April 23, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/31010443/recent-trends-in-neurosurgery-career-outcomes-in-canada
#12
Michael K Tso, J Max Findlay, Stephen P Lownie, M Chris Wallace, Brian D Toyota, Ian G Fleetwood
BACKGROUND: As with other specialties, Royal College of Physicians and Surgeons of Canada (RCPSC) trainees in Neurosurgery have anecdotally had challenges securing full-time employment. This study presents the employment status, research pursuits, and fellowship choices of neurosurgery trainees in Canadian programs. METHODS: RCPSC neurosurgery trainees (n = 143) who began their residency training between 1998 and 2008 were included in this study. Associations between year of residency completion, research pursuits, and fellowship choice with career outcomes were determined by Fisher's exact test (p < 0...
April 23, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30975240/psychiatric-neurosurgery-a-survey-on-the-perceptions-of-psychiatrists-and-residents
#13
Josiane Cormier, Christian Iorio-Morin, David Mathieu, Simon Ducharme
OBJECTIVES: To evaluate the attitudes and perceptions of psychiatrists and psychiatry residents regarding neurosurgical procedures for treating psychiatric disorders and to identify potential barriers to patient referral. METHODS: A survey consisting of 25 questions was created using SurveyMonkey and was distributed to psychiatrists and psychiatry residents in Quebec. The study was approved by the McGill University Health Center's Research Ethics Board. Descriptive statistics and Friedman's test were performed using SPSS software...
April 12, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30975232/characteristic-cerebrovascular-findings-associated-with-acta2-gene-mutations
#14
Andrew Zhang, Alexandria Jo, Karen Grajewski, John Kim
A specific mutation (Arg179) of the ACTA2 gene has previously been described to cause a syndrome of multisystemic smooth muscle dysfunction with an extremely characteristic cerebrovascular appearance.1 Accurate neuroimaging diagnosis of this entity is important as this syndrome predisposes to complications such as early-onset ischemic stroke and ascending thoracic aortic aneurysm.2,3 The following case demonstrates a previously undescribed ACTA2 mutation (Met46) with an identical cerebrovascular imaging appearance to that of Arg179 mutations, but a less severe overall phenotype...
April 12, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30945632/fatal-second-impact-syndrome-in-rowan-stringer-a-17-year-old-rugby-player
#15
Charles Tator, Jill Starkes, Gillian Dolansky, Julie Quet, Jean Michaud, Michael Vassilyadi
Second impact syndrome (SIS) is associated with malignant brain swelling and usually occurs in young athletes with one or more prior, recent concussions. SIS is rare and some dispute its existence. We report a case of SIS in Rowan Stringer, age 17, a rugby player who sustained a fatal brain injury despite prompt medical therapy including decompression surgery. The cause of the massive brain swelling was initially unknown. An inquest revealed Rowan's text messages to friends describing symptoms from two prior, recent rugby brain injuries, likely concussions, within 5 days of the fatal blow and confirming the diagnosis of SIS...
April 4, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30945631/rowan-s-rugby-fatality-prompts-canada-s-first-concussion-legislation
#16
Charles Tator, Jill Starkes, Gillian Dolansky, Julie Quet, Jean Michaud, Michael Vassilyadi
No abstract text is available yet for this article.
April 4, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30944049/step-on-the-gas-focal-seizures-with-autonomic-features
#17
Alyson Plecash, Daryl Wile
No abstract text is available yet for this article.
April 4, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30932801/incidentaloma-discoveries-in-the-course-of-neuroimaging-research
#18
Emmanuel Stip, Jean-Philippe Miron, Marie Nolin, Geneviève Letourneau, Odette Bernazzani, Laurie Chamelian, Bernard Boileau, Mona Gupta, David Luck, Ovidiu Lungu
ABSTRACTAmong healthy volunteers in psychiatric brain functional magnetic resonance imaging (fMRI) research studies, the prevalence of incidentalomas can be as high as 34%, of which 10% show clinical significance. An incidentaloma is a lesion found by coincidence without clinical symptoms or suspicion. Like lesions and other types of accidental findings, it is found in healthy individuals recruited to take part in psychiatric studies. The prevalence of these accidental findings among specific psychiatric populations remains unknown...
April 1, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30932799/eagle-syndrome-as-a-cause-of-cerebral-venous-sinus-thrombosis
#19
Fu-Liang Zhang, Hong-Wei Zhou, Zhen-Ni Guo, Yi Yang
A 15-year-old teenager presented with a 2-month history of headache. Neurological examination was normal except for papilledema. Further lumbar puncture indicated intracranial hypertension (330 mm H2O). Brain magnetic resonance imaging (MRI) was normal but phase contrast-magnetic resonance venography (PC-MRV) (Figure 1(A)) suggested possible left transverse-sigmoid sinus thrombosis; subsequent contrast-enhanced 3D fat-saturated T1 volumetric isotropic turbo spin echo acquisition (VISTA) MRI (Figure 1(B)) confirmed the pathology...
April 1, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30915935/a-survey-of-cerebrospinal-fluid-total-protein-upper-limits-in-canada-time-for-an-update
#20
Pierre R Bourque, Christopher R McCudden, Jodi Warman-Chardon, John Brooks, Harald Hegen, Florian Deisenhammer, Ari Breiner
BACKGROUND: The antiquated standard reference range of 0.15-0.45 g/L for cerebrospinal fluid total protein (CSF-TP) is well entrenched in medical literature and laboratory operating procedures across the world. METHODS: We conducted a web-based survey with a response rate of 34.9% through the listserv of the Canadian Neurological Sciences Federation. Additional laboratory reference data were collated by telephone interview of hospital laboratory technologists across Canada...
March 27, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
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