journal
https://read.qxmd.com/read/38804031/the-association-between-social-support-metabolic-syndrome-and-incidence-of-cardio-cerebrovascular-diseases-in-older-adults-the-arirang-study
#1
JOURNAL ARTICLE
Hae-Kweun Nam, Sei-Jin Chang, Chun-Bae Kim, Kyoung Sook Jeong, Sung-Kyung Kim, Dae Ryong Kang, Yong Whi Jeong, Hocheol Lee, Bo Zhao, Sang-Baek Koh
PURPOSE: We investigated the association between social support, metabolic syndrome, and incident cardio-cerebrovascular disease (CCVD) in rural Koreans aged ≥50 years. MATERIALS AND METHODS: We conducted a prospective study using the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-ARIRANG) dataset. From the baseline of 5169 adults, 1682 participants were finally included according to the exclusion criteria...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804030/pregnancy-outcomes-and-obstetrical-complications-of-twin-pregnancies-with-endometriosis-a-single-center-cohort-study
#2
JOURNAL ARTICLE
Joong Sik Shin, Sujin Kim, Jee Youn Choi, Kirim Hong, Sohyun Shim, Yong Wook Jung, Seok Ju Seong, Hye Sun Jun, Mi-La Kim
PURPOSE: There are many studies regarding the increased relationship between pregnancy outcomes of singleton with endometriosis. However, there was limited evidence of twin pregnancies with endometriosis. This study aimed to compare the pregnancy outcomes and complications in twin pregnancies with or without endometriosis in a single institution. MATERIALS AND METHODS: From January 2011 to July 2022, a retrospective analysis of twin pregnancies was conducted. The endometriosis group included patient with histological or visual confirmation before pregnancy or during cesarean section...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804029/no-change-in-complications-following-thyroidectomy-despite-increase-in-thyroid-cancer-surgeries-a-meta-regression-analysis
#3
JOURNAL ARTICLE
Jun Sung Lee, Jin Seok Lee, Hyeok Jun Yun, Seok-Mo Kim, Hojin Chang, Yong Sang Lee, Juyeon Yang, Hye Sun Lee, Hang-Seok Chang
PURPOSE: The increase in thyroid cancer incidence has inevitably led to an increase in thyroid cancer surgeries. This meta-regression analysis aimed to determine if the rate of post-thyroidectomy complications changes by year. MATERIALS AND METHODS: PubMed and Embase databases were used to perform a systematic literature search of studies published from January 1, 2005, using the keywords "thyroidectomy" and "complication." A meta-regression was performed for post-thyroidectomy hypocalcemia and bleeding...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804028/effect-of-home-based-transcranial-direct-current-stimulation-on-cognitive-function-in-patients-with-mild-cognitive-impairment-a-two-week-intervention
#4
JOURNAL ARTICLE
Jaesub Park, Kyungmi Chung, Yoonkyung Oh, Kwang Joon Kim, Chang Oh Kim, Jin Young Park
PURPOSE: Repeated transcranial direct current stimulation (tDCS) is expected to have the potential to improve cognitive function in patients with mild cognitive impairment (MCI). We aimed to evaluate the efficacy and safety of at-home tDCS for elderly patients with MCI. MATERIALS AND METHODS: Patients aged 60-80 years, who maintained normal daily living but reported objective memory impairments, were enrolled. Active or sham stimulations were applied to the dorsal frontal cortex (left: anode; right: cathode) at home for 2 weeks...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804027/effectiveness-and-safety-of-carbon-ion-radiotherapy-in-solid-tumors-a-systematic-review-and-meta-analysis
#5
JOURNAL ARTICLE
Ji Eun Yun, Sujin Kim, Keun Young Park, Worlsook Lee
PURPOSE: This systematic review and meta-analysis aimed to investigate the effectiveness of carbon ion radiotherapy (CIRT) compared to that of conventional radiotherapy in patients with various types of solid tumors. MATERIALS AND METHODS: We systematically searched eight electronic databases from inception until August 2022 in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The comparative effectiveness of the different treatment options was assessed by a random-effects meta-analysis...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804026/correlation-between-angiotensin-inhibitor-administration-and-longer-survival-in-patients-who-underwent-curative-resection-for-pancreatic-cancer
#6
JOURNAL ARTICLE
Hye Yeon Yang, Min Yu Kang, Chang Moo Kang, Woo Jung Lee, Ho Kyoung Hwang
PURPOSE: The microenvironment of pancreatic ductal adenocarcinoma (PDAC) with extensive desmoplastic stroma contributes to aggressive cancer behavior. Angiotensin system inhibitors (ASIs) reduce stromal fibrosis and are a promising therapeutic strategy. The purpose of this study was to examine how ASIs affected the oncological results of patients who had their PDAC removed. MATERIALS AND METHODS: A retrospective assessment was conducted on the clinicopathological and survival data of patients who received curative resection for PDAC at Severance Hospital between January 2012 and December 2019...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38804025/exercise-across-the-phases-of-cancer-survivorship-a-narrative-review
#7
REVIEW
Ki-Yong An, Jihee Min, Dong Hoon Lee, Dong-Woo Kang, Kerry S Courneya, Justin Y Jeon
Exercise has long been recognized as an important component of treatment for various diseases. However, the benefits and risks of exercise interventions must be carefully evaluated to ensure the former outweighs the latter. As cancer patients undergo diverse treatment modalities with distinct objectives, a systematic approach partitioning the cancer journey into distinct phases is necessary to inform tailored exercise prescriptions. This narrative review summarizes exercise benefits and mechanisms for cancer patients and survivors across four distinct survivorship periods-before surgery, after surgery and before adjuvant treatment, during nonsurgical treatment (adjuvant and neoadjuvant), and during extended survival...
June 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653569/interrupting-effect-of-social-distancing-on-ischemic-heart-disease-asthma-stroke-and-suicide-attempt-patients-by-pm-2-5-exposure
#8
JOURNAL ARTICLE
Minseo Choi, Mia Son, Sanghyuk Bae, Whanhee Lee, Kyung-Nam Kim, Jung K Hyun
PURPOSE: This study aimed to examine the interrupting effect of social distancing (SD) on emergency department (ED) patients with ischemic heart disease (IHD), stroke, asthma, and suicide attempts by PM2.5 exposure in eight Korean megacities from 2017 to 2020. MATERIALS AND METHODS: The study used National Emergency Department Information System and AirKorea data. A total of 469014 patients visited EDs from 2017 to 2020. Interrupted time series analysis was employed to examine changes in the level and slope of the time series, relative risk, and confidence intervals (CIs) by PM2...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653568/prediction-of-high-risk-neuroblastoma-among-neuroblastic-tumors-using-radiomics-features-derived-from-magnetic-resonance-imaging-a-pilot-study
#9
JOURNAL ARTICLE
Jisoo Kim, Young Hun Choi, Haesung Yoon, Hyun Ji Lim, Jung Woo Han, Mi-Jung Lee
PURPOSE: This study aimed to predict high-risk neuroblastoma among neuroblastic tumors using radiomics features extracted from MRI. MATERIALS AND METHODS: Pediatric patients (age≤18 years) diagnosed with neuroblastic tumors who had pre-treatment MR images available were enrolled from institution A from January 2010 to November 2019 (training set) and institution B from January 2016 to January 2022 (test set). Segmentation was performed with regions of interest manually drawn along tumor margins on the slice with the widest tumor area by two radiologists...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653567/diffusion-and-perfusion-weighted-mri-radiomics-for-survival-prediction-in-patients-with-lower-grade-gliomas
#10
JOURNAL ARTICLE
Chae Jung Park, Sooyon Kim, Kyunghwa Han, Sung Soo Ahn, Dain Kim, Yae Won Park, Jong Hee Chang, Se Hoon Kim, Seung-Koo Lee
PURPOSE: Lower-grade gliomas of histologic grades 2 and 3 follow heterogenous clinical outcomes, which necessitates risk stratification. This study aimed to evaluate whether diffusion-weighted and perfusion-weighted MRI radiomics allow overall survival (OS) prediction in patients with lower-grade gliomas and investigate its prognostic value. MATERIALS AND METHODS: In this retrospective study, radiomic features were extracted from apparent diffusion coefficient, relative cerebral blood volume map, and Ktrans map in patients with pathologically confirmed lower-grade gliomas (January 2012-February 2019)...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653566/safety-of-biologics-and-small-molecules-for-inflammatory-bowel-diseases-in-organ-transplant-recipients
#11
JOURNAL ARTICLE
Ga Hee Kim, Minjun Kim, Kyuwon Kim, Jung-Bin Park, Ji Eun Baek, June Hwa Bae, Seung Wook Hong, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Sang Hyoung Park
PURPOSE: This study aimed to evaluate the safety of biologics and small molecules for the treatment of inflammatory bowel diseases (IBD) in patients receiving antirejection therapies after organ transplants. MATERIALS AND METHODS: We reviewed the medical records of patients with IBD who received organ transplants at the Asan Medical Center between January 1989 and December 2021. We compared the parameters of patients receiving biologics or small molecules to those of patients without those therapies...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653565/optimal-treatment-approaches-to-intestinal-beh%C3%A3-et-s-disease-complicated-by-myelodysplastic-syndrome-the-kasid-and-ksbd-multicenter-study
#12
MULTICENTER STUDY
Jung-Bin Park, So Jung Han, Seung Bum Lee, Dong Hyun Kim, Jae Hee Cheon, Sung Wook Hwang, Byong Duk Ye, Suk-Kyun Yang, Soo Jung Park, Sang Hyoung Park
PURPOSE: Studies on intestinal Behçet's disease (BD) complicated by myelodysplastic syndrome (MDS) are rare, and no established therapeutic guidelines exist. This study aimed to evaluate the clinical presentation and outcomes of patients with intestinal BD complicated by MDS (intestinal BD-MDS) and suggest a treatment strategy. MATERIALS AND METHODS: Data from patients with intestinal BD-MDS from four referral centers in Korea who were diagnosed between December 2000 and December 2022 were retrospectively analyzed...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653564/simultaneous-viability-assessment-and-invasive-coronary-angiography-using-a-therapeutic-ct-system-in-chronic-myocardial-infarction-patients
#13
JOURNAL ARTICLE
Seongmin Ha, Yeonggul Jang, Byoung Kwon Lee, Youngtaek Hong, Byeong-Keuk Kim, Seil Park, Sun Kook Yoo, Hyuk-Jae Chang
PURPOSE: In a preclinical study using a swine myocardial infarction (MI) model, a delayed enhancement (DE)-multi-detector computed tomography (MDCT) scan was performed using a hybrid system alongside diagnostic invasive coronary angiography (ICA) without the additional use of a contrast agent, and demonstrated an excellent correlation in the infarct area compared with histopathologic specimens. In the present investigation, we evaluated the feasibility and diagnostic accuracy of a myocardial viability assessment by DE-MDCT using a hybrid system comprising ICA and MDCT alongside diagnostic ICA without the additional use of a contrast agent...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38653563/recent-update-on-acute-kidney-injury-to-chronic-kidney-disease-transition
#14
REVIEW
Eun Sil Koh, Sungjin Chung
Acute kidney injury (AKI) is characterized by an abrupt decline of excretory kidney function. The incidence of AKI has increased in the past decades. Patients diagnosed with AKI often undergo diverse clinical trajectories, such as early or late recovery, relapses, and even a potential transition from AKI to chronic kidney disease (CKD). Although recent clinical studies have demonstrated a strong association between AKI and progression of CKD, our understanding of the complex relationship between AKI and CKD is still evolving...
May 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515362/the-first-case-of-a-korean-patient-with-a-mutation-confirmed-tumor-necrosis-factor-receptor-associated-periodic-syndrome
#15
Seok-Jin Lee, Jee Yeon Baek, Ji Young Lee, Ji-Man Kang, Jong Gyun Ahn
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS, OMIM: #142680) is a rare autoinflammatory disease (AID) with recurrent febrile episodes. To our knowledge, we report herein the first case of a patient with TRAPS in South Korea whose symptoms included fever, arthralgia, abdominal pain, rash, myalgia, cough, and lymphadenopathy. A pathogenic de novo mutation, c.175T>C (p.Cys59Arg), in the tumor necrosis factor receptor superfamily member 1A ( TNFRSF1A ) gene, was confirmed by gene sequencing...
April 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515361/trend-in-the-incidence-of-severe-partial-edentulism-among-adults-using-the-korean-national-health-insurance-service-claim-data-2014-2018
#16
JOURNAL ARTICLE
Hyeonjeong Go, Hoi-In Jung, Song Vogue Ahn, Jeonghoon Ahn, Hosung Shin, Atsuo Amano, Youn-Hee Choi
PURPOSE: Missing teeth is one of the most important indicators of oral health behavior and the result of dental caries, periodontal disease, and injuries. This study examined a trend in the incidence of severe partial edentulism (SPE) using the Korean National Health Insurance Service (KNHIS) data. MATERIALS AND METHODS: Data of adults aged ≥20 years were obtained from the KNHIS for the 2014-2018 period. SPE was defined in dental information within a population with a treatment history of dental scaling as having 1 to 8 natural teeth...
April 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515360/physical-activity-induced-modification-of-the-association-of-long-term-air-pollution-exposure-with-the-risk-of-depression-in-older-adults
#17
JOURNAL ARTICLE
Woongbi Park, Heeseon Jang, Juyeon Ko, Jungwoo Sohn, Young Noh, Sun-Young Kim, Sang-Baek Koh, Changsoo Kim, Jaelim Cho
PURPOSE: Evidence suggests that long-term air pollution exposures may induce depression; however, the influence of physical activity on this effect is unclear. We investigated modification of the associations between air pollution exposures and depression by the intensity of physical activity. MATERIALS AND METHODS: This cross-sectional study included 1454 Korean adults. Depression was defined as a Geriatric Depression Scale score ≥8. Concentrations of particulate matter (PM10 and PM2...
April 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515359/effect-of-dietary-habits-on-alzheimer-s-disease-progression
#18
JOURNAL ARTICLE
So Hyun Ahn, Jee Hyang Jeong, Kyung Won Park, Eun-Joo Kim, Soo Jin Yoon, Bora Yoon, Jae-Won Jang, Yangki Minn, Seong Hye Choi
PURPOSE: Research on the relationship between diet and dementia among Koreans are lacking. This study investigated the association between dietary habits and dementia progression over 3 years in patients with Alzheimer's disease dementia (ADD). MATERIALS AND METHODS: This study included 705 patients with mild-to-moderate ADD. Dietary habits were assessed using the Mini Dietary Assessment Index, comprising 10 questions. Outcome measures included the Clinical Dementia Rating scale-Sum of Boxes (CDR-SB), Seoul-Instrumental Activities of Daily Living, Caregiver-Administered Neuropsychiatric Inventory (CGA-NPI), and neuropsychological test battery (NTB) z-scores, which were evaluated annually over 3 years...
April 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515358/application-of-data-mining-technology-in-the-screening-for-gallbladder-stones-a-cross-sectional-retrospective-study-of-chinese-adults
#19
JOURNAL ARTICLE
Shuang Wang, Chenhui Bao, Dongmei Pei
PURPOSE: The purpose of this study was to use data mining methods to establish a simple and reliable predictive model based on the risk factors related to gallbladder stones (GS) to assist in their diagnosis and reduce medical costs. MATERIALS AND METHODS: This was a retrospective cross-sectional study. A total of 4215 participants underwent annual health examinations between January 2019 and December 2019 at the Physical Examination Center of Shengjing Hospital Affiliated to China Medical University...
April 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38515357/evidence-of-placental-villous-inflammation-and-apoptosis-in-third-trimester-symptomatic-sars-cov-2-maternal-infection
#20
JOURNAL ARTICLE
Manggala Pasca Wardhana, Kuntaman Kuntaman, Budi Utomo, Rozi Aditya Aryananda, Salsabila Nabilah Rifdah, Ifan Ali Wafa, Almira Aulia Shahnaz, Dahlia Ningrum, Nareswari Imanadha Cininta, Grace Ariani, Jan Mm Van Lith, Erry Gumilar Dachlan
PURPOSE: In view of conflicting reports on the ability of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) to infect placental tissue, this study aimed to further evaluate the impact of inflammation and placental damage from symptomatic third-trimester maternal COVID-19 infection. MATERIALS AND METHODS: This case-control study included 32 placenta samples each from symptomatic COVID-19 pregnancy and normal non-COVID-19 pregnancy. The villous placental area's inflammatory expression [angiotensin converting enzyme-2 (ACE-2), transmembrane protease serine-2 (TMPRSS2), interferon-γ (IFN-γ), interleukin-6 (IL-6), and SARS-CoV-2 spike protein] and apoptotic rate were examined using immunohistochemistry and Terminal deoxynucleotidyl transferase dUTP Nick-End Labeling (TUNEL) assay...
April 2024: Yonsei Medical Journal
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