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Yonago Acta Medica

Akihiro Fujita, Shinji Tanishima, Yoshihiro Kato, Ryota Teshima, Hideki Nagashima
Background: Musculoskeletal infections are often seen in the daily practice of orthopedics. Several markers [white blood cell (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT)] have been used for diagnosing these infections. However, these markers may be elevated due to surgery or trauma, and may not be infection-related. These markers also show drug-dependent dynamics during infection that differ from its usual dynamics. Such situations make diagnosis of infections difficult, and Cluster of Differentiation 64 (CD64) has been brought to attention...
December 2018: Yonago Acta Medica
Yuka Matsuura, Masayoshi Oguri, Yoshiaki Saito, Yasutaka Aoe, Ayame Ogawa, Shota Akiyama, Nanako Yasuda, Kengo Sato, Yoshihiro Maegaki, Yasuaki Hirooka
Background: This study aims to elucidate the effect of isolated cerebellar lesions sparing the brainstem on the auditory brainstem responses in children. Methods: We enrolled 10 children (aged 1-16 years) with cerebellar lesions on neuroimaging but lacking clinical brainstem involvement signs and with normal brainstem volumes on magnetic resonance imaging. Results: The interpeak latency of waves I and V was normal in 9 patients and was marginally prolonged in 1 patient...
December 2018: Yonago Acta Medica
Takayoshi Kimura, Tsuyoshi Kawai, Yasufumi Ohuchi, Shinsaku Yata, Akira Adachi, Youhei Takeda, Kazuo Yashima, Soichiro Honjo, Naruo Tokuyasu, Toshihide Ogawa
Background: Bile leakage after hepatectomy is a common complication. The purpose of the present study was to retrospectively evaluate the usefulness of non-surgical management of bile leakage after hepatectomy, using 12-year data from a single center study. Methods: Data from 15 patients (13 men, two women; mean age 67.1 ± 7.0 years) who had undergone non-surgical management for bile leakage between January 2005 and November 2017 were retrospectively reviewed. Results: We categorized bile leakage as central ( n = 5) or peripheral ( n = 10) leakage based on communication with the biliary tree...
December 2018: Yonago Acta Medica
Natsumi Tanaka, Kenichi Takeda, Yuji Kawasaki, Kohei Yamane, Yasuhiko Teruya, Masahiro Kodani, Tadashi Igishi, Akira Yamasaki
Background: Weight loss in patients with cancer is caused by cancer cachexia and chemotherapy-induced nausea and vomiting (CINV). Recent developments in antiemetic drugs have substantially improved CINV, but nutritional intervention did not improve body weight. This study aimed to investigate the effects of nutrition intervention with appropriate antiemetic treatment in patients with non-small-cell lung cancer during chemotherapy. Methods: Patients received individualized nutrition counseling by a registered dietitian and were provided with oral supplements for 90 days...
December 2018: Yonago Acta Medica
Ei Uchinaka, Masataka Amisaki, Masaki Morimoto, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Hiroaki Saito, Yoshiyuki Fujiwara
Background: The neutrophil lymphocyte ratio (NLR) has been proposed to be a surrogate marker of inflammation and immunological status and to have prognostic value in various malignancies. This study was conducted to clarify the prognostic significance of preoperative NLR in hepatocellular carcinoma (HCC). Methods: We enrolled 135 patients with histologically-proven HCC who underwent initial curative hepatectomy. Based on the median NLR values, patients were divided into: NLR ≥ 2...
December 2018: Yonago Acta Medica
Weibin Qian, Junichi Hasegawa, Jie Yang, Yusuke Endo, Junichiro Miake
Background: Daijokito (DJKT), a classical traditional Kampo and Chinese medicine, has been used to treat acute pancreatitis in China. In our previous study, DJKT was found to reduce the area under the plasma concentration-time curve (AUC) of ranitidine in humans. Therefore, we established a novel rat model to examine the direct absorption of ranitidine after daijokito administration. Methods: An in situ intestinal injection with portal vein sampling (IIPS) model was created to determine the rate of intestinal drug absorption...
December 2018: Yonago Acta Medica
Wataru Miyauchi, Yuji Shishido, Yusuke Kono, Yuki Murakami, Hirohiko Kuroda, Yoji Fukumoto, Tomohiro Osaki, Teruhisa Sakamoto, Soichiro Honjo, Keigo Ashida, Hiroaki Saito, Yoshiyuki Fujiwara
The standard procedure for remnant gastric cancer after esophago-proximal gastrectomy is total resection of the remnant stomach considering blood supply. However, sometimes surgery may be too invasive due to severe adhesion in the thoracic and mediastinal cavity. The blood supply to the remnant stomach depends on the right gastroepiploic artery and the right gastric artery. Therefore, preservation of the proximal region of the remnant stomach is thought to be anatomically impossible. We report a case of remnant gastric cancer that developed more than 12 years after lower thoracic esophagectomy plus proximal gastrectomy for Siewert Type I squamous cell carcinoma...
September 2018: Yonago Acta Medica
Teruhisa Sakamoto, Yosuke Arai, Masaki Morimoto, Masataka Amisaki, Naruo Tokuyasu, Soichiro Honjo, Keigo Ashida, Hiroaki Saito, Shinsaku Yata, Yasufumi Ohuchi, Yoshiyuki Fujiwara
Portal vein stenosis, which results in serious clinical conditions such as gastrointestinal variceal bleeding and liver failure, is caused by hepatobiliary pancreatic cancer or major postoperative complications after hepatobiliary pancreatic surgery. In recent years, portal vein stenting under interventional radiology has been applied as a more useful treatment method for portal vein stenosis than invasive surgery. We herein report the successful use of a vascular stent for portal vein stenosis after pancreatoduodenectomy...
September 2018: Yonago Acta Medica
Hiroaki Saito, Yusuke Kono, Yuki Murakami, Yuji Shishido, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Tomohiro Osaki, Keigo Ashida, Yoshiyuki Fujiwara
Background: Therapeutic value of lymph node dissection along the superior mesenteric vein (14v) and the posterior surface of the pancreatic head (13) remains unclear in gastric cancer patients. Methods: We reviewed 355 patients with advanced gastric cancer in the lower third of the stomach who had undergone gastrectomy at our hospital. Results: The frequency of lymph node (LN) metastasis was 10.2% and 7.4% in stations 13 and 14v, respectively...
September 2018: Yonago Acta Medica
Haruka Aoto, Hikaru Nakatani, Shunsuke Kanayama, Shin-Ichi Okada, Mika Fukada, Keiichi Hanaki
Background: Pediatric chronic renal disease only shows abnormal values in a urinalysis in the initial stage, and subjective signs and symptoms are rare. If adolescents with chronic renal disease face a disease crisis combined with the usual developmental crisis, this may cause psychosocial maladaptation. We analyzed psychosocial adaptation in Japanese children with chronic renal disease in order to identify factors influencing healthy adaptation. Methods: Ten children and adult patients with chronic kidney disease attending Tottori University Hospital, Japan in 2016 participated in a semi-structured interview (a modified version of the grounded theory approach) comprising questions about episodes since disease onset and thoughts/feelings at onset...
September 2018: Yonago Acta Medica
Ikuko Nishio, Masami Chujo
Background: In this study, we aim to highlight the transformation of self-image in patients with type 1 diabetes after diagnosis. Our objective in examining the self-image of these patients is to provide practical insights for nursing, as well as a basic reference for understanding patients. Methods: The participants were 15 patients (2 men and 13 women) over 20 years of age who visited an outpatient setting to treat type 1 diabetes and had no serious complications, and who agreed to participate in the study...
September 2018: Yonago Acta Medica
Katsuya Hikita, Masashi Honda, Yusuke Kimura, Bunya Kawamoto, Panagiota Tsounapi, Shuichi Morizane, Atsushi Takenaka
Background: Dysfunction of the lower urinary tract is the most common complication of radical hysterectomy (RH). However, there are no established treatment protocols for postoperative underactive bladder (PUB). We developed our own new program for the treatment of underactive bladder (UB) after RH and evaluated it retrospectively. Methods: In this program, there are five steps for patients to follow according to their urinary condition. The first step is the administration of urapidil 30 mg, voiding six times at a predetermined time each day, and clean intermittent catheterization (CIC) after each voiding...
September 2018: Yonago Acta Medica
Toshihide Ogawa, Shinya Fujii, Keita Kuya, Shin-Ichiro Kitao, Yuki Shinohara, Mana Ishibashi, Yoshio Tanabe
An accurate diagnosis of Parkinson's disease (PD) is a prerequisite for therapeutic management. In spite of recent advances in the diagnosis of parkinsonian disorders, PD is misdiagnosed in between 6 and 25% of patients, even in specialized movement disorder centers. Although the gold standard for the diagnosis of PD is a neuropathological assessment, neuroimaging has been playing an important role in the differential diagnosis of PD and is used for clinical diagnostic criteria. In clinical practice, differential diagnoses of PD include atypical parkinsonian syndromes such as dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, caused by a striatal dopamine deficiency following nigrostrial degeneration...
September 2018: Yonago Acta Medica
Suguru Shiraya, Yoshinobu Nakamura, Yoshikazu Fujiwara, Shingo Harada, Yuichiro Kishimoto, Takeshi Onohara, Yuki Otsuki, Motonobu Nishimura
One complication of an autogenous arteriovenous fistula (AVF) for hemodialysis is the formation of a venous aneurysm. The treatment of a massive aneurysmal AVF generally involves ligation or resection with the use of prosthetic interposition. We present the case of a 46-year-old man in whom an AVF aneurysm was successfully treated by placating the excess free wall of the aneurysm with sutures. This method is a simple and effective intervention for managing aneurysm-associated complications. In addition, this approach helps to maintain the benefits of autogenous access while conserving future dialysis sites...
June 2018: Yonago Acta Medica
Ryoko Kimura, Kazunari Sugita, Hiroyuki Goto, Osamu Yamamoto
We report a case of squamous cell carcinoma manifested as a cutaneous horn. A 92-year-old man was referred to our department for evaluation of a 3-month history of a keratotic cutaneous horn on the left side of his neck. The height of the cutaneous horn was larger than the diameter of erythema at the base. Histopathological examination showed a hyperkeratotic horn developing over a mass of large atypical keratinocytes with large hyperchromatic and pleomorphic nuclei. Based on these findings, a diagnosis of squamous cell carcinoma was made...
June 2018: Yonago Acta Medica
Ryoko Kimura, Kazunari Sugita, Osamu Yamamoto
We present an unusual case of cystic pilomatricoma. A 13-year-old Japanese boy was referred to our department for evaluation of a 10-day history of a small reddish nodule on his right cheek. Histopathological examination showed a well-circumscribed cystic structure showing a central empty cavity in the dermis. The wall of the cyst was composed of basophilic cells. Inner layers of the wall were covered with flattened epithelial cells having trichohyalin granules. Based on these findings, a diagnosis of cystic pilomatricoma was made...
June 2018: Yonago Acta Medica
Naruo Tokuyasu, Kohei Shomori, Kuniki Amano, Soichiro Honjo, Teruhisa Sakamoto, Joji Watanabe, Masataka Amisaki, Masaki Morimoto, Ei Uchinaka, Takuki Yagyu, Hiroaki Saito, Hisao Ito, Yoshiyuki Fujiwara
Background: Indirubin, a constituent of the Chinese herbal medicine "Qing-Dai," has anti-cancer and anti-inflammatory activities. We aimed to evaluate the efficacy of indirubin for ameliorating colonic inflammation in a mouse model of inflammatory bowel disease. Methods: Mice with dextran sulfate sodium (DSS)-induced acute and chronic colitis were treated with indirubin in their diet. Clinical and histologic changes were evaluated. In addition, colon levels of interleukin-6, a critical pro-inflammatory mediator, was detected by enzyme-linked immunosorbent assay...
June 2018: Yonago Acta Medica
Eiji Matsusue, Yoshio Fujihara, Kenichiro Tanaka, Yuki Aozasa, Manabu Shimoda, Hiroyuki Nakayasu, Kazuhiko Nakamura, Toshihide Ogawa
Background: 123 I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 123 I-FP-CIT dopamine transporter single photon emission computed tomography (DAT-SPECT) provide specific information that distinguish Parkinson's disease (PD) from parkinsonian syndromes other than PD (non-PD), including atypical parkinsonian disorder (APD) and non-PD other than APD (nPD-nAPD). The purpose of this study was to determine whether combining DAT-SPECT and MIBG myocardial scintigraphy using multiparametric scoring system (MSS) could improve diagnostic test accuracy in discriminating PD from APD or discriminating PD from nPD-nAPD...
June 2018: Yonago Acta Medica
Naoko Mukuda, Shinya Fujii, Chie Inoue, Takeru Fukunaga, Tetsuro Oishi, Tasuku Harada, Toshihide Ogawa
Background: We investigated the distinguishing pathological features of bilateral ovarian tumors using magnetic resonance (MR) imaging. Methods: Eighty-six patients with bilateral ovarian tumors on MR imaging were evaluated. The pathological diagnosis was investigated, and the results were subjected to statistical analysis using Mann-Whitney U test, Fisher's exact test, Chi-squared test and receiver operating characteristic (ROC) curve to determine the features useful for the differentiation of distinct types of lesions...
June 2018: Yonago Acta Medica
Satoshi Koba
In congestive heart failure (CHF), sympathetic nervous system is hyperactive. This article reviews current understandings about central and peripheral neural mechanisms underlying sympathetic hyperactivation in this pathological condition. During the development of CHF, renin-angiotensin system (RAS) activities and angiotensin II-mediated oxidative stress become enhanced. Here, on the basis of findings obtained from animal studies, it is examined how RAS overactivation and oxidative stress in central and peripheral nervous systems of CHF mediate sympathetic hyperactivation...
June 2018: Yonago Acta Medica
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