journal
https://read.qxmd.com/read/36924102/an-international-comparison-of-haemoglobin-deferral-prediction-models-for-blood-banking
#1
JOURNAL ARTICLE
Marieke Vinkenoog, Jarkko Toivonen, Tinus Brits, Dorien de Clippel, Veerle Compernolle, Surendra Karki, Marijke Welvaert, Amber Meulenbeld, Katja van den Hurk, Joost van Rosmalen, Emmanuel Lesaffre, Mikko Arvas, Mart Janssen
BACKGROUND AND OBJECTIVES: Blood banks use a haemoglobin (Hb) threshold before blood donation to minimize donors' risk of anaemia. Hb prediction models may guide decisions on which donors to invite, and should ideally also be generally applicable, thus in different countries and settings. In this paper, we compare the outcome of various prediction models in different settings and highlight differences and similarities. MATERIALS AND METHODS: Donation data of repeat donors from the past 5 years of Australia, Belgium, Finland, the Netherlands and South Africa were used to fit five identical prediction models: logistic regression, random forest, support vector machine, linear mixed model and dynamic linear mixed model...
March 16, 2023: Vox Sanguinis
https://read.qxmd.com/read/36922182/comment-on-white-paper-on-pandemic-preparedness-in-the-blood-supply
#2
LETTER
Veronica C Hoad, Philip Kiely, Clive R Seed, Iain B Gosbell
No abstract text is available yet for this article.
March 15, 2023: Vox Sanguinis
https://read.qxmd.com/read/36922181/reply-to-hoad-et-al-comment-on-white-paper-on-pandemic-preparedness-in-the-blood-supply
#3
LETTER
Paul Strengers, Sheila F O'Brien, Constantina Politis, Wolfgang Mayr, Erhard Seifried, Bryan R Spencer
No abstract text is available yet for this article.
March 15, 2023: Vox Sanguinis
https://read.qxmd.com/read/36912154/digital-polymerase-chain-reaction-to-monitor-platelet-transfusions-in-cardiac-surgery-patients
#4
JOURNAL ARTICLE
Khaldoun Ali, Thomas H Müller, Henk S P Garritsen, Wolfgang Harringer, Andrea Doescher
BACKGROUND AND OBJECTIVES: Corrected count increment (CCI) measurements monitor the effectiveness of platelet transfusions in haemato-oncology, but they usually fail in patients undergoing cardiac surgery. We investigated whether polymerase chain reaction (PCR) of mitochondrial single-nucleotide polymorphisms (SNPs) is able to monitor the survival of transfused platelets in these patients. MATERIALS AND METHODS: Leukocyte-free, platelet-rich plasma was prepared from patients' blood to measure platelet counts based on patient-/donor-specific SNPs by digital PCR after DNA extraction...
March 13, 2023: Vox Sanguinis
https://read.qxmd.com/read/36908196/dslk-and-kg-antithetical-antigens-in-the-rhag-blood-group-system-and-characterization-of-anti-dslk-antibody
#5
JOURNAL ARTICLE
Toru Miyazaki, Kazumi Isa, Ryo Kurita, Wataru Ohashi, Yuichi Tone, Kenichi Ogasawara, Shigeki Miyata, Masahiro Satake
BACKGROUND AND OBJECTIVES: The RHAG blood group system contains five antigens: Duclos (RHAG001), Ola (RHAG002), DSLK (RHAG003), Kg (RHAG005) and SHER (RHAG006). Individuals who are DSLK-negative and Kg-positive have the same allele RHAG*01.-3, with a single-nucleotide variation (rs144305805), c.490A>C (p.Lys164Gln), in exon 3 of the RHAG gene. We aimed to confirm whether DSLK and Kg are antithetical antigens. MATERIALS AND METHODS: Blood samples of the original DSLK-negative proband with anti-DSLK, her son and another DSLK-negative individual were examined...
March 12, 2023: Vox Sanguinis
https://read.qxmd.com/read/36897221/low-neutralization-capacity-against-sars-cov-2-omicron-bq-1-1-of-convalescent-plasma-collected-during-circulation-of-omicron-ba-1
#6
LETTER
Pierre Gallian, Nadége Brisbarre, Elif Nurtop, Sophie Le Cam, Touret Franck, Christine Isnard, Lucile Malard, Syria Laperche, Pascale Richard, Pascal Morel, Pierre Tiberghien, Xavier de Lamballerie
No abstract text is available yet for this article.
March 10, 2023: Vox Sanguinis
https://read.qxmd.com/read/36896484/use-of-selective-phenotyping-and-genotyping-to-identify-rare-blood-donors-in-canada
#7
JOURNAL ARTICLE
Bryan Tordon, Celina Montemayor, Gwen Clarke, Sheila F O'Brien, Mindy Goldman
BACKGROUND AND OBJECTIVES: The distribution of rare and specific red cell phenotypes varies between races and ethnicities. Therefore, the most compatible red cell units for patients with haemoglobinopathies and other rare blood requirements are most likely to be found in donors from similar genetic backgrounds. Our blood service introduced a voluntary question asking donors to provide their racial background/ethnicity. Results triggered additional phenotyping and/or genotyping. MATERIALS AND METHODS: We analysed the results of additional testing performed between January 2021 and June 2022, and rare donors were added to the Rare Blood Donor database...
March 9, 2023: Vox Sanguinis
https://read.qxmd.com/read/36896482/first-donor-haemovigilance-system-at-a-national-level-in-china-establishment-and-improvement
#8
JOURNAL ARTICLE
Junhong Yang, Dinrong Fan, Dongfu Xie, Xiaojie Guo, Wenqing Zhu, Tao He, Xia Huang
BACKGROUND AND OBJECTIVES: No systematic study has measured the incidence of adverse reactions (ARs) to blood donation at the national level in China before 2019. The objective of this study was to establish an effective reporting system to collect information on ARs to blood donation in China. MATERIALS AND METHODS: The status of donor haemovigilance (DHV) in blood collection facilities in China was evaluated, and an online DHV system was established to collect data on ARs to blood donation in July 2019...
March 9, 2023: Vox Sanguinis
https://read.qxmd.com/read/36896479/secretor-status-of-blood-group-o-mothers-is-associated-with-development-of-abo-haemolytic-disease-in-the-newborn
#9
JOURNAL ARTICLE
Grethe Risum Krog, Henriette Lorenzen, Frederik Banch Clausen, Morten Hanefeld Dziegiel
BACKGROUND AND OBJECTIVES: Identification of antibody characteristics and genetics underlying the development of maternal anti-A/B linked to inducing haemolytic disease of the foetus and newborn could contribute to the development of screening methods predicting pregnancies at risk with high diagnostic accuracy. MATERIALS AND METHODS: We examined 73 samples from mothers to 37 newborns with haemolysis (cases) and 36 without (controls). The secretor status was determined by genotyping a single nucleotide polymorphism in FUT2, rs601338 (c...
March 9, 2023: Vox Sanguinis
https://read.qxmd.com/read/36880992/safety-profile-of-plasma-for-fractionation-donated-in-the-united-kingdom-with-respect-to-variant-creutzfeldt-jakob-disease
#10
REVIEW
Stephen Thomas, Barnaby Roberts, Dragoslav Domanović, Koen Kramer, Denis Klochkov, Sujan Sivasubramaniyam, Dana Miloslavich, Jean-Philippe Plançon, Françoise Rossi, Dominika Misztela, Lauren Kirkpatrick, Gail Miflin, Janet Birchall, Lorna McLintock, Richard Knight
Plasma-derived medicinal products (PDMPs) are life-saving and life-improving therapies, but the raw material is in short supply: Europe depends on importation from countries including the United States. Plasma from donors resident in the United Kingdom has not been fractionated since 1999 when a precautionary measure was introduced in response to the outbreak of variant Creutzfeldt-Jakob disease (vCJD). Cases of vCJD have been far fewer than originally predicted in the 1990s. Since the introduction of leucodepletion in 1999, and accounting for the incubation period, more than 40 million UK-derived blood components have been issued with no reports of TT vCJD...
March 7, 2023: Vox Sanguinis
https://read.qxmd.com/read/36866649/the-estimated-negative-impacts-on-the-red-blood-cell-inventory-of-reducing-shelf-life-at-two-large-health-authorities-in-british-columbia-canada-using-a-discrete-event-simulation-model
#11
JOURNAL ARTICLE
Sakara Hutspardol, Lawrence Sham, David Zamar, Amardeep Singh Sekhon, Tina Jacobucci, Colleen Chan, Rodrigo Onell, Andrew W Shih
BACKGROUND AND OBJECTIVES: Reducing the maximum red blood cell (RBC) shelf-life is under consideration due to potential negative effects of older blood. An assessment of the impacts of this change on blood supply chain management is evaluated. MATERIALS AND METHODS: We performed a simulation study using data from 2017 to 2018 to estimate the outdate rate (ODR), STAT order and non-group-specific RBC transfusion at two Canadian health authorities (HAs). RESULTS: Shortening shelf-life from 42 to 35 and 28 days led to the following: ODRs (in percentage) in both HAs increased from 0...
March 3, 2023: Vox Sanguinis
https://read.qxmd.com/read/36862116/a-novel-quantitative-method-to-evaluate-the-contribution-of-platelet-products-to-white-thrombus-formation-in-reconstituted-blood-under-flow-conditions
#12
JOURNAL ARTICLE
Akihiro Fuchizaki, Kazuta Yasui, Tomoya Hayashi, Mitsunobu Tanaka, Tomoka Nagasato, Tomoko Ohnishi-Wada, Kazuya Hosokawa, Yoshihiro Fujimura, Kazushige Shimogaki, Fumiya Hirayama, Yoshihiro Takihara, Takafumi Kimura
BACKGROUND AND OBJECTIVES: Currently, the quality of platelet (PLT) products is evaluated using a series of in vitro tests, which only analyse PLTs as an inspection material. However, it would be ideal to assess the physiological functions of PLTs under conditions similar to the sequential blood haemostatic process. In this study, we attempted to establish an in vitro system where the thrombogenicity of PLT products was evaluated in the presence of red blood cells (RBCs) and plasma using a microchamber under constant shear stress (600/s)...
March 2, 2023: Vox Sanguinis
https://read.qxmd.com/read/36852764/blood-donor-retention-and-iron-deficiency-anaemia-in-sub-saharan-africa-a-call-for-more-robust-donor-screening-methods
#13
JOURNAL ARTICLE
Donald Vhanda, Collins Timire, Itai James Blessing Chitungo, Frank Chinowaita, Sisodwa Zamani Nkomo, Svitsai Chagonda, Brenda Nherera, Tafadzwa Dzinamarira, Vinie Kouamou
No abstract text is available yet for this article.
February 28, 2023: Vox Sanguinis
https://read.qxmd.com/read/36847193/investigation-of-the-intronic-variant-rhd-c-1154-31c-t-designated-as-rhd-01el-37
#14
LETTER
Xue Rui, Hongjun Gao, Yu Zhang, Ji-Ling Xu, Chengtao He, Qiang Fu
No abstract text is available yet for this article.
February 27, 2023: Vox Sanguinis
https://read.qxmd.com/read/36847186/eye-drops-of-human-origin-current-status-and-future-needs-report-on-the-workshop-organized-by-the-isbt-working-party-for-cellular-therapies
#15
JOURNAL ARTICLE
Christian Gabriel, Denese C Marks, Reinhard Henschler, Katharina Schallmoser, Thierry Burnouf, Mickey B C Koh
BACKGROUND AND OBJECTIVES: Serum eye drops (SEDs) are used to treat ocular surface disease (OSD) and to promote ocular surface renewal. However, their use and production are not standardized, and several new forms of human eye drops have been developed. MATERIALS AND METHODS: The International Society for Blood Transfusion Working Party (ISBT WP) for Cellular Therapies held a workshop to review the current types of eye drops of human origin (EDHO) status and provide guidance...
February 27, 2023: Vox Sanguinis
https://read.qxmd.com/read/36807587/haemovigilance-giving-it-our-best-shot
#16
JOURNAL ARTICLE
Erica M Wood, Barbee I Whitaker, Mary Townsend
No abstract text is available yet for this article.
February 20, 2023: Vox Sanguinis
https://read.qxmd.com/read/36762629/international-forum-on-transfusion-education-for-healthcare-professionals-who-administer-blood-to-patients-in-hospitals-and-health-services-responses
#17
JOURNAL ARTICLE
Arwa Z Al-Riyami, Linley Bielby, Rachel Moss, Naomi Rahimi-Levene, Aine O'Kane, John R Hess, Noor E Saba, Kyeong-Hee Kim, Satyam Arora, Seema Dua, Claire L Barrett, Carlos A Gonzalez, David Martin Ferrari, Paula V Cini, Midori Kumagawa, Claire O'Reilly, Liz Thrift, Silvano Wendel, Roberta Fachini, Lara Faria Souza Dias, Dung Tran, Christine T Steinsvåg, Nancy Dunbar
No abstract text is available yet for this article.
February 10, 2023: Vox Sanguinis
https://read.qxmd.com/read/36762626/international-forum-on-transfusion-education-for-healthcare-professionals-who-administer-blood-to-patients-in-hospitals-and-health-services-summary
#18
JOURNAL ARTICLE
Arwa Z Al-Riyami, Linley Bielby, Rachel Moss, Naomi Rahimi-Levene, Aine O'Kane, John R Hess, Noor E Saba, Kyeong-Hee Kim, Satyam Arora, Seema Dua, Claire L Barrett, Carlos A Gonzalez, David Martin Ferrari, Paula V Cini, Midori Kumagawa, Claire O'Reilly, Liz Thrift, Silvano Wendel, Roberta Fachini, Lara Faria Souza Dias, Dung Tran, Christine T Steinsvåg, Nancy Dunbar
No abstract text is available yet for this article.
February 10, 2023: Vox Sanguinis
https://read.qxmd.com/read/36740822/prediction-of-blood-volume-to-be-processed-to-achieve-a-target-number-of-cd34-cells-development-validation-and-implementation-of-a-formula
#19
JOURNAL ARTICLE
Irene García-García, Joan Cid, Gemma Moreno-Jiménez, María Tenorio Núñez, Ana Jiménez Martín, Ana Vallés Carboneras, Kyra Velázquez-Kennedy, Miquel Lozano, Francisco-Javier López-Jiménez
BACKGROUND AND OBJECTIVES: Calculation of blood volume (BV) to be processed to achieve the target number of CD34+ cells can be accomplished by using collection efficiency 2 (CE2) formula. Our aim was to develop a BV web formula. MATERIALS AND METHODS: We calculated CE2 from aphereses performed between January 2015 and March 2020 in allogeneic donors and patients. From May 2020 to May 2021, we validated a formula: BV = ((Target CD34+ cells in the product)/(CD34+ pre-apheresis cells × CE2)) × 100...
February 5, 2023: Vox Sanguinis
https://read.qxmd.com/read/36734378/pathogen-reduction-with-methylene-blue-does-not-have-an-impact-on-the-clinical-effectiveness-of-covid-19-convalescent-plasma
#20
JOURNAL ARTICLE
Irene Romera Martínez, José Luis Bueno Cabrera, José María Domingo-Morera, Juan Carlos López Aguilar, Carolina Villegas Da Ros, José Antonio García Erce, Isabel Sáez Serrano, Elena Flores Ballester, Laura Analía Maglio, Cristina Arbona Castaño, Carlos Sola Lapeña, Luisa Guerra Domínguez, Margarita Berberana Fernández, María Elena Madrigal Sánchez, Martín Rubio Batllés, Mayte Pérez-Olmeda, Antonio Ramos-Martínez, Ana Velasco-Iglesias, Cristina Avendaño-Solá, Rafael F Duarte
BACKGROUND AND OBJECTIVES: There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of immunoglobulins of COVID-19 convalescent plasma (CCP). We have evaluated whether MB-treated CCP is associated with a poorer clinical response compared to other inactivation systems at the ConPlas-19 clinical trial. MATERIALS AND METHODS: This was an ad hoc sub-study of the ConPlas-19 clinical trial comparing the proportion of patients transfused with MB-treated CCP who had a worsening of respiration versus those treated with amotosalen (AM) or riboflavin (RB)...
February 3, 2023: Vox Sanguinis
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