Science Progress

In recent years, the adhesive technology has been widely used in the production of high-strength joins and precise positioning of various materials, such as metals, glass and composite materials. The adhesive technology has become a promising assembly process in the aerospace field due to its versatility, low creep and high damage tolerance. However, the reliability and predictability of adhesive bonding still require further development due to the complex operating conditions involved. Therefore, this article reviews and discusses the latest advances in aerospace adhesive technology, such as methods for improving bonding performance, bonding techniques (including joints structure and failure modes) and self-healing adhesive layers...

Idiopathic pulmonary fibrosis is a chronic and progressive interstitial lung disease with a poor prognosis. Idiopathic pulmonary fibrosis is characterized by repeated alveolar epithelial damage leading to abnormal repair. The intercellular microenvironment is disturbed, leading to continuous activation of fibroblasts and myofibroblasts, deposition of extracellular matrix, and ultimately fibrosis. Moreover, pulmonary fibrosis was also found as a COVID-19 complication. Currently, two drugs, pirfenidone and nintedanib, are approved for clinical therapy worldwide...

Team sports involve various sprinting actions, including curvilinear sprints, yet their neuromuscular factors have been understudied. The aim of this cross-sectional study was to investigate the relationship between lower limb muscle strength, strength asymmetries, linear sprint and curvilinear sprint performance. At two visits 12 male (age: 24.8 ± 4.7 years, height: 1.82 ± 0.06 m, body mass: 80 ± 6.58 kg) and 6 female (age: 20.8 ± 1...

Treacher Collins syndrome (TCS) is a rare congenital craniofacial disorder, typically inherited as an autosomal dominant condition. Here, we report on a family in which germline mosaicism for TCS was likely present. The proband was diagnosed with TCS based on the typical clinical features and a pathogenic variant TCOF1 (c.4369_4373delAAGAA, p.K1457Efs*12). The mutation was not detected in his parents' peripheral blood DNA samples, suggesting a de novo mutation had occurred in the proband. However, a year later, the proband's mother became pregnant, and the amniotic fluid puncture revealed that the fetus carried the same mutation as the proband...

METHODOLOGY: An electronic search was done in PUBMED, SCOPUS, and a hand search was done in radiology, periodontology, and oral surgery journals. The search yielded 428 results, from which only 6 articles were selected for this literature review. Both prospective and retrospective studies were included. Clinical studies with information on the pre-implant condition of the site, detailed implant procedure, and follow-up after implant placement of more than 6 months were only considered for this review...

This research aims to optimize the silk and wool dyeing process using natural dyes from Bixa orellana (annatto) through response surface methodology. Central composite design experiments highlight the significant enhancement of color outcomes achieved through microwave treatment. For silk, the optimal conditions (80 °C for 40 min) with annatto extract yield a color strength (K/S) of 17.8588, while wool achieves a K/S of 7.5329. Introducing eco-friendly bio-mordants, such as pomegranate peel and red sumac tannins, enhances color strength...

BACKGROUND: Most children with neurocritical illness are at risk of physical, neurocognitive, and psychosocial sequelae and need centralized early rehabilitation care. OBJECTIVE: To identify the effectiveness and safety of centralized early rehabilitation care for children with severe acquired brain injury. METHODS: This is a mixed methods study-an implementation study and single-center retrospective cohort study with historical control. All children with severe acquired brain injury hospitalized in a specialized rehabilitation center in a comprehensive tertiary pediatric hospital between September 2016 and August 2020 were included...

In alignment with the distributional hypothesis of language, the work "Quantum Projections on Conceptual Subspaces" (Martínez-Mingo A, Jorge-Botana G, Martinez-Huertas JÁ, et al. Quantum projections on conceptual subspaces. Cogn Syst Res 2023; 82: 101154) proposed a methodology for generating conceptual subspaces from textual information based on previous work (Martinez-Mingo A, Jorge-Botana G and Olmos R. Quantum approach for similarity evaluation in LSA vector space models. 2020). These subspaces enable the utilization of the quantum model of similarity put forth by Pothos and Busemeyer (Pothos E, Busemeyer J...

Objective: This pilot study assessed the effects of electronic noise-masking earbuds on subjective sleep perception and objective sleep parameters among healthcare workers (HCWs) reporting sleep difficulties during the COVID-19 pandemic. Methods: Using a pre-post design, 77 HCWs underwent 3 nights of baseline assessment followed by a 7-night intervention period. Participants wore an at-home sleep monitoring headband to assess objective sleep measures and completed subjective self-report assessments. The difference in mean sleep measures from baseline to intervention was estimated in linear mixed models...

BACKGROUND: Ischemia-reperfusion injury (IRI) poses a significant challenge for physicians, necessitating the management of cell damage and the preservation of organ functions. Various surgical procedures, such as vascular surgery on extremities, temporary cross-clamping of the abdominal aorta in aortic surgery, and the use of a tourniquet in extremity surgeries, may induce lower limb IRI. The susceptibility to IRI is heightened in individuals with diabetes. This study aimed to investigate the effects of fullerenol C60 and sevoflurane on mouse muscle tissue in a lower limb IRI model and to assess their potential in preventing complications arising from ischemia-reperfusion in mice with streptozocin-induced diabetes...

Bone extracellular matrix (ECM) proteins play a key role in bone formation and regeneration, including structural and regulatory functions. The Phylobone database consists of 255 ECM protein groups from 39 species and can be used to support bone research. Here, we gathered bone ECM proteins from reindeer ( Rangifer tarandus ), a member of the Cervidae family. The importance of reindeer lies in their ability to regenerate their antlers, in both male and female individuals. Protein sequences were extracted from the National Center for Biotechnology Information's repository and selected by homology searches...

The Republic of South Africa is one of the leading investors in renewable energy in Africa, despite the widespread perception that the country is trapped in the carbon age due to its high dependence on fossil fuels. Renewable energy, rooted in sustainable development, requires the creation of an appropriate framework and environmentally friendly technologies to support growth. Renewable energy sources are considered more environmentally friendly than fossil fuels, which most energy processes rely on. For this reason, the scope of this article has been narrowed to focus on the motivation for renewable energy and its potential in South Africa...

In our 2023 paper, entitled "Modeling interactions between the embodied and the narrative self: Dynamics of the self-pattern within LIDA," Kugele, Newen, Franklin, and I propose a functional description and implementation of a central element of Gallagher & Newen's pattern theory of self, which identifies an agent's self with a dynamic pattern of so-called cognitive aspects which govern their thought and behavior (Gallagher, 2013; Newen, 2018; Gallagher & Daly, 2018). The pattern theory explicitly rejects the traditional conceptualization of the self as a unitary entity with certain properties that resides within agents, with the idea of a pattern of aspects being central to its ability to account for the dynamic, yet relatively stable development of most natural agents' selves...

This study aimed to investigate the impact of the Nordic hamstring exercises (NHE) on acute fatigue-induced alterations in the mechanical and morphological properties of hamstring muscles. The second aim was to define the blood flow and perfusion after NHE in recreational active volunteers. Twenty-two individuals volunteered to participate in the study. This study investigated fatigue outcomes: rate of perceived exertion (RPE) scale and average force generated during NHE; mechanical properties (stiffness); morphological properties (thickness, pennation angle, and fascicle length), and vascularity index (VI) of the semitendinosus (ST) and biceps femoris long head (BFLH) at baseline, immediately post-exercise and 1-h post-exercise...

No abstract text is available yet for this article.

The avoidance of causality in the design, analysis and interpretation of non-experimental studies has often been criticised as an untenable scientific stance, because theories are based on causal relations (and not associations) and a rich set of methodological tools for causal analysis has been developed in recent decades. Psychology researchers (n = 106 with complete data) participated in an online study presenting a causal statement about the results of a fictitious paper on the potential effect of drinking clear water for years on the risk of dementia...

This study investigated the effects of match location, quality of opposition (classified into: strong [1st to 4th position]; intermediate [5th to 15th position]; weak [16th to 20th position]), and match outcome on the match running performance of starters and non-starters from a top elite Brazilian soccer team. Absolute measures were calculated using total distance, high-speed (19.8-25.2 km·h-1 ), sprinting (≥ 25.2 km·h-1 ), total distance high-acceleration (> 2m·s2 ) , and deceleration (< -2m·s2 ) were recorded by GPS units from a sample of young soccer players ( N  = 25) in a total of 17 matches...

Nasopharyngeal carcinoma is a malignant tumor that occurs in the epithelium and mucosal glands of the nasopharynx, and its pathological type is mostly poorly differentiated squamous cell carcinoma. Since the nasopharynx is located deep in the head and neck, early diagnosis and timely treatment are critical to patient survival. However, nasopharyngeal carcinoma tumors are small in size and vary widely in shape, and it is also a challenge for experienced doctors to delineate tumor contours. In addition, due to the special location of nasopharyngeal carcinoma, complex treatments such as radiotherapy or surgical resection are often required, so accurate pathological diagnosis is also very important for the selection of treatment options...

Aiming at the flexible manipulator grasping complex target parts of different shapes, a double-finger flexible manipulator model is proposed. The manipulator is composed of a flexible mechanical finger, a driving component and a position compensation mechanism. It imitates the motion characteristics of human finger joints and follows the principle of double-fingered grasping. According to the structural characteristics of the target contour, the grasping features of the target contour are extracted. Through the motion principle of the flexible manipulator, the kinematic model of the envelope clamping process of the manipulator target is carried out...

OBJECTIVES: Research progress of human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) based on immune microenvironment. METHODS: This article preliminarily discusses the composition of immune microenvironment components and immune therapy and elaborates and analyzes the involvement and impact of T cells, B cells, natural killer (NK) cells, tumor-associated fibroblasts, and bone marrow-derived suppressor cells in HPV-positive HNSCC on tumor progression and prognosis...