journal
https://read.qxmd.com/read/38594125/impact-of-microbubble-degradation-and-flow-velocity-on-subharmonic-aided-pressure-estimation-shape-an-experimental-investigation
#1
JOURNAL ARTICLE
Li Zhang, Yi-Fan Dong, Yao Chen, Xiao-Gang Li, Ya-Hong Wang, Ying Wang, Zhi-Tong Ge, Xin Wang, Sheng Cai, Xiao Yang, Qing-Li Zhu, Jian-Chu Li
OBJECTIVE: This study aimed to investigate the impact of microbubble degradation and flow velocity on Sub-Harmonic Aided Pressure Estimation (SHAPE), and to explore the correlation between subharmonic amplitude and pressure as a single factor. METHODS: We develop an open-loop vascular phantom platform system and utilize a commercial ultrasound machine and microbubbles for subharmonic imaging. Subharmonic amplitude was measured continuously at constant pressure and flow velocity to assess the impact of microbubble degradation...
April 8, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38584023/the-utility-of-a-novel-stacked-microvascular-imaging-for-enhanced-detection-of-fibrosis-in-chronic-liver-diseases
#2
JOURNAL ARTICLE
Daisuke Miura, Hiromi Suenaga, Kiyoshi Ichihara
OBJECTIVE: Ultrasonographic imaging plays a primary role to detect fibrotic changes in patients with chronic liver disease (CLD). To enhance detectability of fibrosis in its early stage, we developed a novel stacked microvascular imaging (SMVI) that enables continuous visualization of fibrotic changes in intrahepatic vessels. METHODS: SMVI was produced by accumulating 3-5 seconds of high-definition color images in tilted-scan mode. An SMVI score was devised by quantitating three hallmark vascular changes in liver fibrosis in 0-2 grades (total 0-6): narrowing, caliber irregularity, and tortuosity...
April 6, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38575417/ultrasound-based-predictive-model-to-assess-the-risk-of-orbital-malignancies
#3
JOURNAL ARTICLE
Yuli Zhang, Youyi Huang, Jie Bi, Haiyan Zhou, Tao Li, Jingqin Fang
OBJECTIVE: Ultrasound (US) is widely used for evaluating various orbital conditions. However, accurately diagnosing malignant orbital masses using US remains challenging. We aimed to develop an ultrasonic feature-based model to predict the presence of malignant tumors in the orbit. METHODS: A total of 510 patients with orbital masses were enrolled between January 2017 and April 2023. They were divided into a development cohort and a validation cohort. In the development cohort (n = 408), the ultrasonic and clinical features with differential values were identified...
April 3, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38575416/long-term-ultrasound-twinkling-detectability-and-safety-of-a-polymethyl-methacrylate-soft-tissue-marker-compared-to-conventional-breast-biopsy-markers-a-preclinical-study-in-a-porcine-model
#4
JOURNAL ARTICLE
Christine U Lee, Matthew W Urban, Gina K Hesley, Benjamin G Wood, Thomas R Meier, Beiyun Chen, Blake A Kassmeyer, Nicholas B Larson, A Lee Miller, James L Herrick, James W Jakub, Mara A Piltin
OBJECTIVE: We have studied the use of polymethyl methacrylate (PMMA) as an alternative biopsy marker that is readily detectable with ultrasound Doppler twinkling in cases of in vitro, ex vivo, or limited duration in vivo settings. This study investigates the long-term safety and ultrasound Doppler twinkling detectability of a PMMA breast biopsy marker following local perturbations and different dwell times in a 6-mo animal experiment. METHODS: This study, which was approved by our Institutional Animal Care and Use Committee, involved three pigs and utilized various markers, including PMMA (Zimmer Biomet), 3D-printed, and Tumark Q markers...
April 3, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38575415/corrigendum-to-safety-review-of-therapeutic-ultrasound-for-spinal-cord-neuromodulation-and-blood-spinal-cord-barrier-opening-ultrasound-in-med-biol-50-2024-317-331
#5
Rui Xu, Bradley E Treeby, Eleanor Martin
No abstract text is available yet for this article.
April 3, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38575414/a-preliminary-study-on-the-application-of-contrast-enhanced-ultrasonography-in-children-with-peripheral-neuroblastic-tumors
#6
REVIEW
Ting Wang, Dan Han, Huan Xiao, Hao Yang, Jing-Yu Chen, Yi Tang
The purpose of this study was to retrospectively analyze the characteristics of contrast-enhanced ultrasound (CEUS) images and quantitative parameters of time-intensity curves (TICs) in children's peripheral neuroblastic tumors (pNTs). By comparing the imaging features and quantitative parameters of the TICs of neuroblastoma (NB) and ganglioneuroblastoma (GNB) patients, we attempted to identify the distinguishing points between NB and GNB. A total of 35 patients confirmed to have pNTs by pathologic examination were included in this study...
April 3, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38548527/evaluation-of-dual-frequency-switching-hifu-for-optimizing-superficial-ablation
#7
JOURNAL ARTICLE
Wenchang Huang, Yang Jiao, Jiaqi Li, Yan He, Weiwei Shao, Yaoyao Cui
OBJECTIVE: Dual-frequency high-intensity focused ultrasound (HIFU) thermal ablation is an exceptionally promising technique for treating tumors due to its precision and effectiveness. However, there are still a few studies on improving the accuracy and efficiency of HIFU in superficial ablation applications. This study proposes a method utilizing dual frequency switching ultrasound (DFSU) to enhance the efficiency and precision of superficial treatments. METHODS: A dual-frequency HIFU transducer operating at 4...
March 27, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38538443/commentary-on-neuroinflammation-in-the-rat-brain-after-exposure-to-diagnostic-ultrasound-by-lalzad-wong-and-schneider
#8
LETTER
Gail Ter Haar, Jacques Abramowicz, Brian Fowlkes, Felix Schlachetzki
No abstract text is available yet for this article.
March 26, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38538442/synchronized-chemotherapy-photothermal-therapy-sonodynamic-therapy-of-human-triple-negative-and-estrogen-receptor-positive-breast-cancer-cells-using-a-doxorubicin-gold-nanoclusters-albumin-nanobioconjugate
#9
JOURNAL ARTICLE
Zahra Kayani, Hossein Heli, Rezvan Dehdari Vais, Hanieh Haghighi, Mohammadreza Ajdari, Naghmeh Sattarahmady
OBJECTIVE: Novel strategies for treating triple-negative breast cancer (TNBC) are ongoing because of the lack of standard-of-care treatment. Nanoframed materials with a protein pillar are considered a valuable tool for designing multigoals of energy-absorbing/medication cargo and are a bridge to cross-conventional treatment strategies. METHODS: Nanobioconjugates of gold nanoclusters-bovine serum albumin (AuNCs-BSA) and doxorubicin-AuNCs-BSA (Dox-AuNCs-BSA) were prepared and employed as a simultaneous double photosensitizer/sonosensitizer and triple chemotherapeutic/photosensitizer/sonosensitizer, respectively...
March 26, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38521696/evaluation-of-left-ventricular-function-in-patients-with-severe-aortic-stenosis-utilizing-automated-cardiac-motion-quantitation-techniques
#10
JOURNAL ARTICLE
Jing He, Zi-Xin Yang, Wen-Long Zhang, Hai-Zhou Zhang, Mei Zhu
OBJECTIVE: The objective of this study is to explore the patterns of alteration in left ventricular systolic function among patients with severe aortic stenosis (SAS) through the application of automatic myocardial motion quantification (aCMQ) techniques. Furthermore, we seek to ascertain dependable quantitative markers for the assessment of impaired left ventricular function in patients with SAS and an ejection fraction (EF) ≥ 60%. METHODS: Seventy patients who underwent echocardiography and received a diagnosis of severe aortic stenosis (SAS) in the hospital from November 2021 to August 2022 were selected for the SAS group and categorized into three subgroups based on ejection fraction (EF)-SAS group with EF ≥ 60%, SAS group with EF ranging from 50% to 59%, and SAS group with EF < 50%...
March 22, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38521695/development-of-an-mr-guided-focused-ultrasound-mrgfus-lesioning-approach-for-the-fornix-in-the-rat-brain
#11
JOURNAL ARTICLE
Carena Cornelssen, Allison Payne, Dennis L Parker, Matthew Alexander, Robb Merrill, Sharayu Senthilkumar, Jacob Christensen, Karen S Wilcox, Henrik Odéen, John D Rolston
OBJECTIVE: High-intensity magnetic resonance-guided focused ultrasound (MRgFUS) is a non-invasive therapy to lesion brain tissue, used clinically in patients and pre-clinically in several animal models. Challenges with focused ablation in rodent brains can include skull and near-field heating and accurately targeting small and deep brain structures. We overcame these challenges by creating a novel method consisting of a craniectomy skull preparation, a high-frequency transducer (3 MHz) with a small ultrasound focal spot, a transducer positioning system with an added manual adjustment of ∼0...
March 22, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38519361/ultrasound-secondary-signs-for-the-diagnosis-of-pediatric-distal-forearm-fractures-a-diagnostic-study
#12
JOURNAL ARTICLE
Peter J Snelling, Philip Jones, David Bade, Alan Gillespie, Gerben Keijzers, Robert S Ware
OBJECTIVE: To evaluate the diagnostic accuracy of ultrasound secondary signs of fractures in pediatric patients aged 5-15 y presenting to the emergency department with a clinically non-deformed distal forearm injury. METHODS: This diagnostic study was conducted in South East Queensland, Australia. Emergency clinicians performed point-of-care ultrasound on eligible patients and recorded secondary signs of fractures (pronator quadratus hematoma [PQH] sign, periosteal hematoma, visible angulation) or physeal fractures (fracture-to-physis distance [FPD], physis alteration)...
March 21, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38519360/determining-ultrasound-parameters-for-bursting-polymer-microbubbles-for-future-use-in-spinal-cord-injury
#13
JOURNAL ARTICLE
Brian E Oeffinger, Maria Stanczak, Angelo C Lepore, John R Eisenbrey, Margaret A Wheatley
OBJECTIVE: We believe our poly(lactic acid) (PLA) microbubbles are well suited for therapeutic delivery to spinal cord injury (SCI) using ultrasound-triggered bursting. We investigated the feasibility of clinical ultrasound bursting in situ, the optimal bursting parameters in vitro and the loading and release of a model bio-active DNA. METHODS: Microbubbles were tested using clinical ultrasound in a rat cadaver SCI model. Burst pressure thresholds were determined using the change in enhancement after ultrasound exposure...
March 21, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38514364/hydrochloric-acid-induced-acute-lung-injury-models-dynamic-change-and-quantitative-analysis-of-modified-lung-ultrasound-scoring-system-and-high-resolution-computed-tomography
#14
JOURNAL ARTICLE
Jingyi Guo, Youkuan Ou, Qiuyue Liu, Kunzhang Zeng, Yijun Huang, Fuqiang Yan, Mingli Cai, Guorong Lyu
OBJECTIVE: Acute lung injury (ALI) has become a research hotspot due to its significant public health impact. To explore the value of the use of modified lung ultrasound (MLUS) scoring system for evaluating ALI using a rabbit model of ALI induced by hydrochloric acid (HCl) and investigate its correlation with high-resolution computed tomography (HRCT) and histopathological scores. METHODS: Twenty New Zealand laboratory rabbits were randomly assigned to control group (N = 5) and 3 experimental groups (N = 5 each)...
March 20, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38514363/elastic-properties-of-aging-human-hematoma-model-in-vitro-and-its-susceptibility-to-histotripsy-liquefaction
#15
JOURNAL ARTICLE
Ekaterina M Ponomarchuk, Pavel B Rosnitskiy, Sergey A Tsysar, Tatiana D Khokhlova, Maria M Karzova, Anastasia V Kvashennikova, Kseniia D Tumanova, Alexey V Kadrev, Sergey V Buravkov, Pavel E Trakhtman, Nicolay N Starostin, Oleg A Sapozhnikov, Vera A Khokhlova
OBJECTIVE: Tissue susceptibility to histotripsy disintegration has been reported to depend on its elastic properties. This work was aimed at investigation of histotripsy efficiency for liquefaction of human hematomas, depending on their stiffness and degree of retraction over time (0-10 d). METHODS: As an in vitro hematoma model, anticoagulated human blood samples (200 mL) were recalcified at different temperatures. In one set of samples, the shear modulus was measured by shear wave elastography during blood clotting at 10℃, 22℃ and 37℃, and then daily during further aging...
March 20, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38494413/localization-and-risk-stratification-of-thyroid-nodules-in-ultrasound-images-through-deep-learning
#16
JOURNAL ARTICLE
Zhipeng Wang, Xiuzhu Wang, Ting Wang, Jianfeng Qiu, Weizhao Lu
OBJECTIVE: Deep learning algorithms have commonly been used for the differential diagnosis between benign and malignant thyroid nodules. The aim of the study described here was to develop an integrated system that combines a deep learning model and a clinical standard Thyroid Imaging Reporting and Data System (TI-RADS) for the simultaneous segmentation and risk stratification of thyroid nodules. METHODS: Three hundred four ultrasound images from two independent sites with TI-RADS 4 thyroid nodules were collected...
March 16, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38485534/automatic-detection-and-tracking-of-anatomical-landmarks-in-transesophageal-echocardiography-for-quantification-of-left-ventricular-function
#17
JOURNAL ARTICLE
Anders Austlid Taskén, Jinyang Yu, Erik Andreas Rye Berg, Bjørnar Grenne, Espen Holte, Håvard Dalen, Stian Stølen, Frank Lindseth, Svend Aakhus, Gabriel Kiss
OBJECTIVE: Evaluation of left ventricular (LV) function in critical care patients is useful for guidance of therapy and early detection of LV dysfunction, but the tools currently available are too time-consuming. To resolve this issue, we previously proposed a method for the continuous and automatic quantification of global LV function in critical care patients based on the detection and tracking of anatomical landmarks on transesophageal heart ultrasound. In the present study, our aim was to improve the performance of mitral annulus detection in transesophageal echocardiography (TEE)...
March 13, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38485533/recommendations-for-the-cleaning-of-endocavity-ultrasound-transducers-between-patients
#18
REVIEW
Susan Campbell Westerway, Jocelyne M Basseal, Jacques Abramowicz, Carmel Moran
The COVID-19 pandemic highlighted the importance of infection prevention and control measures for all medical procedures, including ultrasound examinations. As the use of ultrasound increases across more medical modalities, including point-of-care ultrasound, so does the risk of possible transmission from equipment to patients and patients to patients. This is particularly relevant for endocavity transducers, such as trans-vaginal, trans-rectal and trans-oesophageal, which could be contaminated with organisms from blood, mucosal, genital or rectal secretions...
March 13, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38471999/in-vivo-validation-of-an-in-situ-calibration-bead-as-a-reference-for-backscatter-coefficient-calculation
#19
JOURNAL ARTICLE
Yuning Zhao, Gregory J Czarnota, Trevor H Park, Rita J Miller, Michael L Oelze
OBJECTIVE: The study described here was aimed at assessing the capability of quantitative ultrasound (QUS) based on the backscatter coefficient (BSC) for classifying disease states, such as breast cancer response to neoadjuvant chemotherapy and quantification of fatty liver disease. We evaluated the effectiveness of an in situ titanium (Ti) bead as a reference target in calibrating the system and mitigating attenuation and transmission loss effects on BSC estimation. METHODS: Traditional BSC estimation methods require external references for calibration, which do not account for ultrasound attenuation or transmission losses through tissues...
March 12, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38471998/cardiac-2-d-shear-wave-imaging-using-a-new-dedicated-clinical-ultrasound-system-a-phantom-study
#20
JOURNAL ARTICLE
Eric Saloux, Morgane Le Garrec, Nina Menet, Ludovic Dillon, Christophe Simard, Christophe Fraschini, Alain Manrique
OBJECTIVE: The purpose of this study was to assess cardiac shear wave imaging implemented in a new MACH 30 ultrasound machine (SuperSonic Imaging, Aix-en-Provence, France) and interfaced with a linear probe and a phased array probe, in comparison with a previously validated Aixplorer system connected to a linear probe (SuperSonic Imaging) using Elasticity QA phantoms (Models 039 and 049, CIRS Inc., Norfolk, VA, USA). METHODS: Quantile-quantile plots were used for distribution agreement...
March 11, 2024: Ultrasound in Medicine & Biology
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