journal
https://read.qxmd.com/read/38459713/clinical-spectrum-in-microbiologically-proven-demodex-blepharokeratoconjunctivitis-an-observational-study
#1
JOURNAL ARTICLE
Sikha Misra, Somasheila I Murthy, Joveeta Joseph
PURPOSE: To study the demographic, clinical, and microbiological profile of Demodex-related blepharokeratoconjunctivitis (BKC) at a tertiary eye care hospital. METHODS: This retrospective observational study was conducted from January 2016 to September 2022. It included 83 patients with microbiologically proven Demodex BKC who presented to the cornea department of our tertiary care eye center. The clinical, microbiological, and demographic data of the 83 cases were analyzed...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454875/evaluation-of-agreement-in-macular-vascular-density-measured-by-different-protocols-4-5-mm-%C3%A3-4-5-mm-and-6-mm-%C3%A3-6-mm
#2
JOURNAL ARTICLE
Pradeep Sagar, Pagidimarri Divya, Suchitra Biswal, Chaithra Kakunje, B C Pradeep, H N Ravishankar
PURPOSE: To evaluate the agreement in the macular vascular density (MVD) measured by two protocols: 4.5 mm × 4.5 mm and 6 mm × 6 mm. DESIGN: Cross-sectional observational study. METHODS: Healthy volunteers between the age group of 19 and 39 years were recruited. Topcon DRI OCT Triton plus (Topcon Corporation, Tokyo, Japan) was used to acquire the fovea-centered optical coherence tomography angiography (OCTA) image using two protocols: 4...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454874/sideways-sculpting-a-novel-technique-in-eyes-with-posterior-polar-cataracts
#3
JOURNAL ARTICLE
Sourabh D Patwardhan, Nidhi S Patwardhan, Ankita Sangle
Posterior polar cataracts (PPCs) have long been a concern for cataract surgeons due to their natural proclivity for posterior capsule rupture. Although problems can be avoided, there is no surgical procedure that can completely eliminate the possibility of posterior capsular rupture. Research reports a higher percentage of capsule rupture and related complications post surgical intervention. The sideways sculpting technique is a novel method to alleviate unnecessary tension on the posterior capsule. To disseminate this novel technique to practicing ophthalmologists to reduce the risk of complications related to polar cataracts...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454873/tumor-dna-sampling-from-aqueous-humor-in-retinoblastoma-a-report-from-south-asia
#4
JOURNAL ARTICLE
Rachna Meel, Sushil K Sangwan, Sahil Agrawal, Seema Kashyap, Arundhati Sharma
PURPOSE: Retinoblastoma (RB) is the most common intraocular tumor in pediatric age group. The role of genetics has been explored in predicting survival prognosis, but its role in predicting globe salvage remains largely unexplored. We hereby aim to isolate cell-free DNA (cfDNA) from aqueous humor (AH) in RB eyes and validate its use for genetic studies. METHODS: AH was obtained from 26 eyes undergoing enucleation (arm A) or intravitreal chemotherapy (arm B). Isolation of cfDNA was done using QIAamp® Circulating Nucleic Acid kit, and the cfDNA was utilized for targeted sequencing of RB1 gene...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454872/hospital-corneal-retrieval-program-a-long-way-to-go
#5
JOURNAL ARTICLE
Anu Jain, Snigdha Sen, Prerna Upadhyay, Nishi Dwivedi, Lokesh K Singh, Renu Agrawal, Sarvesh Kumar
PURPOSE: The Hospital Corneal Retrieval Program (HCRP) aims to counsel and encourage the family of a critically ill or deceased person in the hospital for eye donation. Adequately sensitized health-care workers (HCWs) may play a pivotal role in boosting HCRP. STUDY DESIGN: Multicentric, cross-sectional, descriptive study. METHODS: Study participants included all HCWs of three medical colleges, including one with eye bank and corneal transplant services...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454871/comparative-study-of-the-three-dimensional-perception-of-videos-recorded-on-a-do-it-yourself-three-dimensional-recording-assembly-versus-the-conventional-recording-system
#6
JOURNAL ARTICLE
M J Aravind, Raju Sampangi, Rouli Sud, Rubina Sheikh, Harpreet Kaur, B C Hemalatha, Sumeet Khanduja
PURPOSE: To develop an indigenous "Do it yourself" (DIY) three-dimensional (3D) ophthalmic surgery recording system and validate the perception of stereopsis using it. METHODS: A cross-sectional survey of practicing ophthalmologists with post-postgraduation experience of at least 5 years for perception of stereopsis for three different surgeries was performed; cataract, retinal detachment, and intravitreal drug injection were recorded on DIY assembly, viewed on VRBOX and using laptop videos and pseudo 3 d videos as control...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454870/outbreak-of-toxic-anterior-segment-syndrome-following-vitreoretinal-surgery-a-retrospective-analysis
#7
JOURNAL ARTICLE
Naresh B Kannan, M Sivadarshan, Avik Dey Sarkar, MuthuKrishnan Vallinayagam, Kim Ramaswamy
BACKGROUND: Toxic anterior segment syndrome (TASS) is an uncommon complication of vitreoretinal surgery and is characterized by severe anterior chamber reaction, hypopyon, and limbus-to-limbus corneal edema. METHODS: Twenty-nine vitreoretinal surgeries were performed, of which 14 developed TASS in the early postoperative period. The operative records were reviewed retrospectively. RESULTS: The median age of patients was 49.07 ± 16.75 years and 14...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454869/an-analysis-of-the-clinical-and-investigative-profile-of-uveitis-in-the-elderly-first-case-series-from-india
#8
JOURNAL ARTICLE
Kowsigan Magesan, Arshee Ahmed, Amala E George, Sudha K Ganesh, Jyotirmay Biswas, Parthopratim Dutta Majumder
PURPOSE: To evaluate the spectrum of uveitis occurring after 60 years of age in elderly patients who presented to a tertiary care eye center in India. METHODS: Retrospective study of patients who visited a tertiary eye care institute between January 2010 and July 2020. RESULT: Eighty-seven patients developed uveitis after 60 years, with only 44.8% having sufficient follow-up documentation and were included in the final analysis. The median age of these patients was 64 (IQR: 62-70) years, and 69% of them were male...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454868/navigating-diagnostic-and-therapeutic-challenges-in-ocular-manifestations-of-hansen-s-disease-and-trachoma-a-narrative-review
#9
JOURNAL ARTICLE
Bharat Gurnani, Kirandeep Kaur, Hritik R Savla, Priyadarshi Prajjwal, Siva Santosh Kumar Pentapati, L V Simhachalam Kutikuppala
Neglected tropical diseases (NTDs) encompass a group of approximately 20 diseases prevalent in tropical and subtropical regions, closely associated with poverty, affecting over a billion people in low-income countries. This manuscript aims to explore the ocular manifestations and burden of two significant NTDs, namely Hansen's disease and trachoma while addressing gaps in understanding and management. Hansen's disease, caused by Mycobacterium leprae, has a long history and presents with diverse neurological and ocular manifestations...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454866/clinicodemographic-profile-of-orbital-exenteration-in-a-tertiary-eye-care-center-a-20-year-experience
#10
JOURNAL ARTICLE
Rachna Meel, Neelam Pushker, Shweta Das Chaurasia, Aishwarya Rathod, Mandeep Singh Bajaj, Seema Sen, Sahil Agrawal
PURPOSE: This study aimed to determine the clinical indications for orbital exenteration, demographic profile of these patients, and clinicopathologic correlations in the current times and to compare these results with previous published data. METHODS: It was a retrospective study. All exenterations performed at a tertiary eye care center over a period of 20 years (from January 2001 to June 2020) were retrospectively evaluated. Patient records were reviewed to obtain demographic data, presenting symptoms and their duration, laterality, and clinical and histopathologic diagnosis...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454865/evolution-of-research-in-diagnosis-and-management-of-uveitis-over-four-decades-in-india
#11
JOURNAL ARTICLE
Jyotirmay Biswas, Sourabh Jadhav, Bhuvaneshwaran V Eswaran
Uveitis and its complications are more common in the developing world, in which the condition occurs in up to 714 per 100,000 in the population and accounts for up to 25% of all blindness. In India, the ophthalmic sub speciality of uveitis greatly evolved in the last four decades. In the early decades most of the studies were epidemiological studies. In recent years, more research has been published due to tremendous advancements in clinical diagnosis, laboratory investigations and ancillary test and treatment modalities...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454864/the-expanding-roles-of-eye-banks-in-india-past-present-and-future
#12
JOURNAL ARTICLE
Sunita Chaurasia, Rohit Dureja, Arvind Roy, Sujata Das
This review highlights the evolution in the scope of eye banking activities in India. The roles and responsibilities of the eye banks have expanded to match the requirements and necessities that arose because of advancements in keratoplasty techniques and the need for corneal surgeons. Adoption of different types of corneal preservation solutions and methods of donor cornea preservation was a consequence of the changing and unprecedented times. The growth of eye banking in India has been a commendable journey and has placed the country in an "almost sufficient" category in eye banking and corneal transplantation...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454863/cataract-surgery-in-children-using-intracameral-mydriatic
#13
JOURNAL ARTICLE
Jaspreet Sukhija, Savleen Kaur, Kiran Kumari, Kajree Gupta, Parul Chawla Gupta
PURPOSE: To study the pupil dynamics with premixed intracameral anesthetic mydriatic combination of phenylephrine (0.31%), tropicamide (0.02%), and lidocaine (1%) in pediatric cataract surgery. METHODS: Consecutive children aged ≤12 years planned for cataract surgery were recruited. A commercially available premixed combination of phenylephrine (0.31%), tropicamide (0.02%), and lidocaine (1%) was injected at the beginning of surgery without any topical/infusion drugs for mydriasis...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454862/outcomes-of-ahmed-glaucoma-valve-surgery-performed-by-glaucoma-fellows-a-large-retrospective-study-from-eastern-india
#14
JOURNAL ARTICLE
Avik K Roy, Sardar M Khan, Aparna Rao
PURPOSE: Teaching and training of glaucoma fellows on the technique of Ahmed glaucoma valve (AGV) implantation surgery is very important. The purpose of this study was to describe the clinical outcomes and complications of AGV surgery performed by glaucoma fellows of a tertiary eye center from eastern India. METHODS: This was a retrospective study based on electronic medical records. Thirty-five eyes operated with AGV by five glaucoma fellows from January 2016 to November 2020 were included...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454860/prognosis-of-concurrent-endoscopic-dacryocystorhinostomy-and-nasal-septoplasty-for-chronic-dacryocystitis-with-moderate-nasal-septum-deviation
#15
JOURNAL ARTICLE
Junge Zhang, Shuai Ming, Huiling Qing, Wei Han, Shichao Li
CONTEXT: The prognosis of combined septoplasty and endoscopic dacryocystorhinostomy (En-DCR) for moderate nasal septum deviation (NSD) has not yet been fully investigated. PURPOSE: To evaluate whether septoplasty improves the prognosis of En-DCR for moderate NSD. SETTINGS AND DESIGN: A retrospective cohort study in a real-world clinical setting. METHODS: The postoperative FICI DCR ostium grading scores and functional and anatomical information at 1, 2, 3, and 6 months were determined for consecutive patients with chronic dacryocystitis (CD) and moderate NSD who underwent En-DCR...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454859/the-scope-of-artificial-intelligence-in-retinopathy-of-prematurity-rop-management
#16
JOURNAL ARTICLE
Puja Maitra, Parag K Shah, Peter J Campbell, Pukhraj Rishi
Artificial Intelligence (AI) is a revolutionary technology that has the potential to develop into a widely implemented system that could reduce the dependence on qualified professionals/experts for screening the large at-risk population, especially in the Indian scenario. Deep learning involves learning without being explicitly told what to focus on and utilizes several layers of artificial neural networks (ANNs) to create a robust algorithm that is capable of high-complexity tasks. Convolutional neural networks (CNNs) are a subset of ANNs that are particularly useful for image processing as well as cognitive tasks...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454858/variations-in-choroidal-thickness-between-emmetropic-and-myopic-eyes-after-caffeine-intake
#17
JOURNAL ARTICLE
Wafa Alotaibi, Mohammed Alhazmi, Salha Khormi, Turki Almaslokh, Muteb Alanazi, Mohammed Althomali
PURPOSE: To investigate the variations in choroidal thinning between emmetropic and myopic subjects after caffeine intake. METHODS: Forty-five healthy participants (age mean ± standard deviation [SD]: 20.75 ± 1.6 years) recruited in a prospective cross-sectional study. They were divided into three groups, based on refractive error status, emmetropes (spherical equivalent [SE] -0.25 to +0.25D), myopes (SE ≥-0.50D to ˂-6.00D), and high myopes (SE ≥-6...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454857/machine-learning-assisted-prediction-of-trabeculectomy-outcomes-among-patients-of-juvenile-glaucoma-by-using-5-year-follow-up-data
#18
JOURNAL ARTICLE
Shweta Birla, Toshit Varshney, Abhishek Singh, Arun Sharma, Arnav Panigrahi, Shikha Gupta, Dinesh Gupta, Viney Gupta
OBJECTIVE: To develop machine learning (ML) models, using pre and intraoperative surgical parameters, for predicting trabeculectomy outcomes in the eyes of patients with juvenile-onset primary open-angle glaucoma (JOAG) undergoing primary surgery. SUBJECTS: The study included 207 JOAG patients from a single center who met the following criteria: diagnosed between 10 and 40 years of age, with an IOP of >22 mmHg in the eyes on two or more occasions, open angle on gonioscopy in both eyes, with glaucomatous optic neuropathy, and requiring a trabeculectomy for IOP control...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454856/quality-and-applicability-of-cadaveric-donor-eyes-for-molecular-biology-research-an-indian-experience
#19
JOURNAL ARTICLE
Prerna Kulshrestha, Sarmeela Sharma, Sushma Vishwakarma, Mohammed J Ali, Tarjani V Dave, Inderjeet Kaur
PURPOSE: Human ocular tissue banking plays an important part in the advancement of translational research for identifying the molecular processes involved in disease etiology and pathogenesis. Timely obtaining a good-quality ocular tissue from a cadaveric donor is exceedingly difficult, especially in remote areas, with a variable transportation time (within 12-24 h), raising concerns about RNA quality and its subsequent applications. Therefore, we assessed the utility of retinal tissues from cadaver donor and enucleated eyes based on the RNA quality and gene expression by real-time polymerase chain reaction (PCR)...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454855/reserve-drug-as-first-line-management-topical-interferon-%C3%AE-2b-for-vernal-keratoconjunctivitis
#20
JOURNAL ARTICLE
Saurabh Ramdas Haral, Taskin Khan, Vishnu S Gupta, Madhura Sanjay Ukalkar
PURPOSE: To elucidate the efficacy and safety profile of interferon α-2b in vernal keratoconjunctivitis (VKC). METHODS: In this prospective interventional study, VKC patients fulfilling the inclusion and exclusion criteria were included and their signs and symptoms were scored based on the Clinical Scoring System. Patients were treated with topical interferon α-2b eye drop (1 MIU/ml) QID dosing for 6 weeks. Changes in symptoms and signs were evaluated at 2, 4, 8 weeks and 6 months after initiating treatment...
March 8, 2024: Indian Journal of Ophthalmology
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