Steven P Treon, Alessandra Tedeschi, Jesus San-Miguel, Ramon Garcia-Sanz, Kenneth C Anderson, Eva Kimby, Monique C Minnema, Giulia Benevolo, Lugui Qiu, Shuhui Yi, Evangelos Terpos, Constantine S Tam, Jorge J Castillo, Pierre Morel, Meletios Dimopoulos, Roger G Owen
Consensus Panel 4 (CP4) of the 11th International Workshop on Waldenstrom's Macroglobulinemia (IWWM-11) was tasked with reviewing the current criteria for diagnosis and response assessment. Since the initial consensus reports of the 2nd International Workshop, there have been updates in the understanding of the mutational landscape of IgM related diseases, including the discovery and prevalence of MYD88 and CXCR4 mutations; an improved recognition of disease related morbidities attributed to monoclonal IgM and tumor infiltration; and a better understanding of response assessment based on multiple, prospective trials that have evaluated diverse agents in Waldenstrom's macroglobulinemia...
April 20, 2023: Seminars in Hematology