Thierry Hannedouche, Patrick Rossignol, Patrice Darmon, Jean-Michel Halimi, Patrick Vuattoux, Albert Hagege, Ludivine Videloup, Francis Guinard
Diabetes is the leading cause of end-stage kidney disease (ESKD), accounting for approximately 50% of patients starting dialysis. However, the management of these patients at the stage of chronic kidney disease (CKD) remains poor, with fragmented care pathways among healthcare professionals (HCPs). Diagnosis of CKD and most of its complications is based on laboratory evidence. This article provides an overview of critical laboratory evidence of CKD and their limitations, such as estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio (UACR), Kidney Failure Risk Equation (KFRE), and serum potassium...
September 21, 2023: Postgraduate Medicine
Betül Öztürk, Mustafa Muhammed Güneyli Oğlu, Raziye Merve Yaradilmiş, Orkun Aydın, Deniz Yasar, Ali Güngör, I Lknur Bodur, Aytaç Göktuğ, I Lker Ufuk Sayici, Utku Arman Örün, Can Demir Karacan, Nilden Tuygun
INTRODUCTION: Cardiological emergencies are reported to constitute almost 15% of all emergency department visits. This study aimed to characterize the main signs and symptoms of the infants that necessitated pediatric cardiology consultation and to analyze the characteristics of patients diagnosed with a cardiological disorder. MATERIAL AND METHODS: Patients aged 1 month to 1 year who were consulted to the pediatric cardiology service during a 4-year period were retrospectively evaluated...
September 20, 2023: Postgraduate Medicine
Ji Won Ko, Seung Eun Lee, Jung Hwan Park, Bongyoung Kim
BACKGROUND: Adrenal insufficiency is one of the causes of fever of unknown origin (FUO). The purpose of this study is to find out risk factors that are associated with adrenal insufficiency in FUO patients. METHODS: This study was conducted retrospectively in a tertiary hospital with 846 beds in South Korea. All adult inpatients (age ≥19 years) who have requested a consult with the department of infectious disease for FUO between 1 July 2019 and 30 June 2020 were included in the study...
September 19, 2023: Postgraduate Medicine
Sencer Ganidagli, Zeynel Abidin Ozturk
BACKGROUND: Aging and type 2 diabetes mellitus (DM) are two different conditions that impair sleep quality. The primary objective of this study was to investigate the impact of sleep quality on geriatric syndromes in older diabetic adults. METHODS: Comprehensive geriatric assessment was performed on 236 patients. The assessment included the Geriatric Depression Scale (GDS), Beck Anxiety Inventory (BAI), European Quality of Life Questionnaire (EQ-5D), Mini Mental Statement Examination (MMSE), Pittsburgh Sleep Quality Index (PSQI), Mini Nutritional Assessment, and measurement of handgrip strength (HGS)...
September 12, 2023: Postgraduate Medicine
Eden Miller, Dominic Raj, Matthew A Cavender, Sherif Mehanna, Tarlan Namvar, Reese Ochsner
OBJECTIVES: Chronic kidney disease (CKD) and atherosclerotic cardiovascular disease (ASCVD) are closely linked conditions, and the presence of each condition promotes incidence and progression of the other. In this study, we sought to better understand the medical journey of patients with CKD and ASCVD and to uncover patients' and healthcare providers' (HCPs) perceptions and attitudes toward CKD and ASCVD diagnosis, treatment, and care coordination. METHODS: Cross-sectional, US-population-based online surveys were conducted between 18 May 2021, and 17 June 2021, among 239 HCPs (70 of whom were primary care physicians, or PCPs) and 195 patients with CKD and ASCVD...
September 11, 2023: Postgraduate Medicine
Minhua Li
OBJECTIVE: The current study evaluated the relationship between serum vitamin C and chronic kidney disease. METHODS: The database from the National Health and Nutrition Examination Survey (NHANES, 2017-2018) was used to perform a cross-sectional study. Multivariate logistic regression was performed to analyze the relationship between serum vitamin C and chronic kidney disease (CKD), and stratified analysis by sex was performed to assess whether there were sex differences in the association between serum vitamin C and CKD...
September 7, 2023: Postgraduate Medicine
Suman Sheraz, Francesco Vincenzo Ferraro, Furqan Ahmed Siddiqui, Hina Tariq, Mark Anthony Faghy, Arshad Nawaz Malik
INTRODUCTION: Inspiratory muscle training (IMT) has been widely used in both healthy and diseased populations especially in older adults, and its effects have been proven not only on inspiratory muscle strength but also on dyspnea, exercise capacity, quality of life and other health parameters. AIM: This study aims to review the effects of IMT on balance and functional ability of healthy and diseased populations. METHODS: A systematic literature search was conducted on MEDLINE, EMBASE, AMED, and Cochrane Central Register of Controlled Trials (CENTRAL)...
August 31, 2023: Postgraduate Medicine
Jee Min Kim, Ji Yoon Han, Seung Beom Han
BACKGROUND: The Omicron variant has been the predominant severe acute respiratory syndrome coronavirus 2 variant circulating in Korea since January 2022. This study evaluated and compared the clinical characteristics of children with coronavirus disease 2019 (COVID-19) between the Delta and Omicron periods. METHODS: The medical records of children aged < 12 years diagnosed with acute COVID-19 (<2 weeks of symptom onset) at seven university-affiliated hospitals were retrospectively reviewed...
August 21, 2023: Postgraduate Medicine
Charles Christian Adarkwah, Oliver Hirsch, Merlissa Menzel, Joachim Labenz
OBJECTIVES: The aim of our study was to compare the results of endoscopy and manometry with regard to the presence and longitudinal size of hiatal hernias using a cohort of patients with PPI-refractory reflux symptoms. In addition, we aimed to investigate the clinical relevance of hiatal hernias and their size in relation to the occurrence of GERD. METHODS: Five hundred patients with suspected GERD due to typical reflux symptoms (heartburn and regurgitation) and inadequate response to PPI therapy underwent standardized screening at a reflux center...
August 12, 2023: Postgraduate Medicine
Run Peng, Rong Yang, Ning Ning
INTRODUCTION: A significant number of rotator cuff tear (RCT) patients developed chronic shoulder pain that did not correspond to physiological changes. Central sensitization syndrome (CSS) is a neurophysiological adaptation process that can result in hypersensitivity to peripheral stimuli. Although there is evidence of an association between CSS and musculoskeletal problems, no studies have focused on the association between CSS and RCT. The primary purpose of this study was to examine the prevalence of CSS in patients with RCT...
July 28, 2023: Postgraduate Medicine
Uğur Özkan, Muhammet Gürdoğan
OBJECTIVE: Spontaneous coronary artery dissection (SCAD) is a rare but potentially life-threatening pathology and cases are especially seen in women under 50 years of age and with relatively fewer cardiovascular risk factors. Although risk factors facilitating the development of SCAD have been defined in the literature, modifiable risk factors remain unclear. In this study, it was aimed to investigate the relationship between the triglyceride glucose index (TyG) and the development of SCAD in the population of young women...
July 28, 2023: Postgraduate Medicine
Claudia B Bittner, Hubert Steindl, Dimitri Abramov-Sommariva, Michael Plach, Christoph Abels, Claus Bachert
OBJECTIVES: To substantiate the clinical efficacy and investigate the real-world effectiveness of the herbal medicinal product BNO 1016 in acute rhinosinusitis (ARS) in the context of antibiotic stewardship. METHODS: We performed a meta-analysis of the clinical trials ARhiSi-1 (EudraCT No. 2008 -002,794-13) and ARhiSi-2 (EudraCT No. 2009 -016,682-28) comprising 676 patients, analyzing the reduction of the Major Symptom Score (MSS) and improvement of the Sino-Nasal Outcome Test 20 (SNOT-20) by the herbal medicinal product BNO 1016...
July 11, 2023: Postgraduate Medicine
Siyu Mu, Jingman Hu, Fangxi Liu, Chuansheng Zhao, Yefei Sun
Many undergraduate students suffer from 'neurophobia,' which refers to a lack of knowledge or confidence in neurology, and this can influence their career choices. Various measures have been taken to address this issue, including the implementation of new technologies and methodologies. Significant advancements have been made in the development of blended learning, and the integration of student-centered learning modules, multimedia, and web-based devices has become a common teaching approach. Nonetheless, the optimal delivery form, as well as assessment for the selected learning format and teaching quality in both theory and clinical practice, are being investigated...
July 10, 2023: Postgraduate Medicine
Panagiotis Theofilis, Aikaterini Vordoni, Rigas G Kalaitzidis
Chronic kidney disease (CKD) remains a pathologic entity with constantly rising incidence and high rates of morbidity and mortality, which are associated with serious cardiovascular complications. Moreover, the incidence of end-stage renal disease tends to increase. The epidemiological trends of CKD warrant the development of novel therapeutic approaches aiming to prevent its development or retard its progression through the control of major risk factors: type 2 diabetes mellitus, arterial hypertension, and dyslipidemia...
August 2023: Postgraduate Medicine
Fatma Aydın, Zeynep Birsin Özçakar, Pınar Özge Avar Aydın, Ece Mekik Akar, Nilgün Çakar
OBJECTIVES: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease. Recurrent fever, serositis, and arthritis are common findings of the disease. In addition, musculoskeletal complaints such as exertional leg pain can be overlooked, although they are common and affect patients' quality of life. The aim of this study was to evaluate the frequency of exertional leg pain in pediatric FMF patients and to analyze the association of this finding with other characteristics of FMF...
June 20, 2023: Postgraduate Medicine
Özlem Çolak, Okşan Derinöz Güleryüz, Yasemin Men Atmaca, Burcu Şenkalfa, Ayla Akca Caglar, Songül Tomar Güneysu
BACKGROUND AND OBJECTIVES: Dermatologic lesions that occur primarily or are secondary to disease are among the most common reasons for referral to the Pediatric Emergency Department (PED). This study aims to reveal the clinical features, diagnostic distribution, and management of patients who presented to the PED with dermatologic lesions. METHODS: The study was a retrospective cross-sectional study involving children aged 0-18 years who presented to Gazi University Faculty of Medicine, PED, in 2018 with dermatologic lesions...
June 15, 2023: Postgraduate Medicine
Angel Lopez-Candales, Scott Monte, Khalid Sawalha, Nicholas B Norgard
No abstract text is available yet for this article.
June 14, 2023: Postgraduate Medicine
Adam Burcheri, Alexandre Coutin, Blair L Bigham, Michael I Kruse, Kelly Lien, Rodrick Lim, Hilary MacCormick, Judy Morris, Victor Ng, Nadia Primiani, Scott Odorizzi, Vincent Poirier, Suneel Upadhye, Robert Primavesi
Social medicine and health advocacy curricula are known to be uncommon in postgraduate medical education. As justice movements work to unveil the systemic barriers experienced by sexual and gender minority (SGM) populations, it is imperative that the emergency medicine (EM) community progress in its efforts to provide equitable, accessible, and competent care for these vulnerable groups. Given the paucity of literature on this subject in the context of EM in Canada, this commentary borrows evidence from other specialties across North America...
June 13, 2023: Postgraduate Medicine
Hicret Yeniay, Bahar Kuvaki, Sule Ozbilgin, Hasan Bahadır Saatli, Hikmet Tunç Timur
OBJECTIVES: This study assessed postoperative mortality, morbidity, and complications associated with anesthesia administration for gynecologic oncology abdominal surgery and investigated the risk factors for the development of these complications. METHODS: We conducted a retrospective cohort study analyzing the data of patients who underwent elective gynecologic oncology surgery between 2010 and 2017. The demographic data; comorbidities; preoperative anemia; Charlson Comorbidity Index; anesthesia management; complications; preoperative, intraoperative, and postoperative periods; mortality; and morbidity were investigated...
June 9, 2023: Postgraduate Medicine
Steven G Chrysant
White-coat hypertension (WCH) has been defined as an increased blood pressure (BP) in the doctor's office and a normal BP outside the office by 24 hr ambulatory BP monitoring (ABPM) or home BP measurement. It is generated by fear and anxiety of whether an abnormal value could be found and indicate the existence of hypertension. When first described, it was defined as a neuro-defense reaction related to the presence of the doctor in their office or clinic and associated with an increase in heart rate...
June 2023: Postgraduate Medicine
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