Nederlands Tijdschrift Voor Geneeskunde

Medication represents an aspect of healthcare with significant opportunity for reduction of environmental impact. Prescribing practitioners play an important role in mitigating this impact through various interventions. This includes minimizing unnecessary medication usage and waste, as well as providing concrete recommendations to diminish the direct and indirect environmental effects of prescribed medications. Unfortunately, the current lack of comprehensive information hinders the selection of the treatment alternatives with the lowest environmental impact...

OBJECTIVE: Differences in payment between men and women are common. The goal of this study was to assess differences in payment in a large Dutch university hospital. METHODS: The Human Resource Management & Organizational BehaviorCenter, University of Groningen conducted the study. Anonymous monthly data from UMCG employees from 2012-2020 (13,212 employees with a permanent appointment and a minimum size of 0.2 Full Time Equivalent (FTE)), were used regarding salary, function, leadership position, department, age, gender, FTE, bonuses and allowances...

A 66-year-old man presented to the general practitioner several times with persistent coughing, haematoma formation and swelling fluctuating in size during coughing. An CT scan showed a widened seventh intercostal space based on a rupture of the intercostal muscles with a herniation of part of the left lower lobe.

OBJECTIVE: Test decisions depend on the context in which health care is delivered. We interviewed paediatricians about perceived societal developments and their influence on diagnostic testing. DESIGN: Qualitative interview study. METHODS: Semi-structured in-depth interviews with 20 practicing Dutch paediatricians. RESULTS: Paediatricians associated societal developments, such as decreased risk acceptance, with perceived pressure from parents to perform tests...

Glucocorticoids are often used long-term at low doses (often 5 mg/day prednisolone or less), but it is still unclear how much we should worry about this. This article provides an indication of the prevalence of such use, discusses the current state of knowledge about the balance of benefit and harm, and provides some suggestions. At this time long-term low dose glucocorticoid therapy appears acceptable under suitable precautions in cases where good alternatives are lacking.

A patient with a swelling of the abdominal wall is a regular occurrence in general practice and hospital. The diagnosis can often be made with a thorough history and physical examination. An abdominal wall hernia is characterized by an increase in swelling on standing physical examination and Valsalva maneuver, which is often reducible, and a hernia defect is palpable. If no interruption of the abdominal wall is palpable and there is hypoesthesia, there may be an abdominal wall paresis because of thoracic paramedian hernia nuclei pulposi (HNP)...

Flucloxacillin-induced hypokalaemia can be progressive and life-threatening, despite of potassium supplementation. In this case description, a high dose of intravenous flucloxacillin was started after a 68-year-old patient presented with an infected knee replacement. After two days, hypokalaemia was noted with an inadequate response to potassium supplementation. It was decided to change antibiotics and increase potassium supplementation, with good results. It is advisable to include monitoring of potassium levels in local treatment protocols when flucloxacillin is prescribed...

Most women use medication during pregnancy. The disposition of drugs may be altered due to changes in pregnant women's bodies. This may call for pregnancy-adjusted doses for certain medications. However, in the face of scarce evidence, such doses are generally lacking, potentially contributing to an increased risk of treatment failure or toxicity in pregnant women and their unborn children. By integrating physiological and/or population data, pharmacokinetic models can be used to determine appropriate medication dosages among pregnant women and their unborn children, as well as other patient groups for which evidence-based doses may be lacking such as children, elderly or obese patients...

OBJECTIVE: To provide an overview of the effectiveness of various forms of home telemonitoring systems for heart failure and the potential role these systems may have in decreasing the burden on healthcare through reduction in heart failure hospitalizations. DESIGN: Meta-analysis of randomized and observational studies. METHODS: A meta-analysis of randomized and observational studies was carried out to assess the effect on mortality and heart failure-related hospitalizations, comparing standard heart failure care with the use of home monitoring systems...

Rapid eye movement (REM) sleep behavior disorder is characterized by dream enactment during REM sleep. Due to different treatment requirements, it is important to distinguish REM sleep behavior disorder from other causes of nocturnal restlessness, including sleep apnea, non-REM parasomnia and sleep-related hypermotor epilepsy. In addition, a diagnosis of isolated REM sleep behavior disorder is impactful, because it carries a greatly increased risk for the later development of Parkinson's disease and related synucleinopathies...

Social security disability assessors are required to objectively quantify disability with regards to potential ability to work. Difficulties arise when assessments need to be performed in the absence of objective medical data relying solely on self-report regarding subjective health complaints. In such cases, validity tests provide a useful tool during an assessment. This case report illustrates this through the outcomes of 3 disability assessments.

In this article, we will address 10 questions about anxiety that are relevant to doctors who encounter this in their practice. This often occurs in the primary care setting, where individuals with anxiety frequently present with somatic complaints. A focused medical history, including questions about the use and withdrawal of psychoactive substances, can assist in the diagnostic process. Psychoeducation may be sufficient, otherwise cognitive-behavioral therapy can be conducted. In cases of non-response, serotonergic antidepressants represent a treatment option...

Due to the rising demand for transgender healthcare, almost every general practitioner (GP) encounters this issue. GPs role in Dutch transgender healthcare often revolves around referring patients to specialized care. However, this field faces challenges, including extended waiting times. Not all patients require referral; some can be supported by their GP. Referral need not always be to a gender clinic; other options exist. This highlights the importance of understanding individual needs to deliver personalized care, which goes beyond the need for specialized treatments like hormonal or surgical interventions...

It regularly occurs that a physicians is abused by a patient. For physicians this may be a reason to consider to end the relationship with such patients, particularly if patients become violent. But is this permitted? The Dutch law and professional standards restrict physicians from doing so, unless there are 'serious reasons' to do so and only after having investigated all possibilities to restore the treatment relationship, including a discussion with the patient. We argue that these restrictions are too strict...

The accessibility of primary care is under pressure, because more and more responsibilities and tasks are being shifted to general practitioners. Changes will have to take place to safeguard the core values of primary care: person-oriented, medical-generalistic and continuous. The increase in chronic diseases and multimorbidity forces general practitioners to delve deeper into complex care and maintain their management role in healthcare. Because of their guiding function, general practitioners must orientate themselves on problem areas that were previously discussed less prominently, such as questions related to gender identity and diversity...

Assessment plays a significant role in the career of medical doctors. Not only are they being assessed, many medical doctors are also involved in teaching which includes the creation of tests. Therefore, knowledge on high quality assessment questions is essential. Multiple-choice questions (MCQs) are commonly used, but allow for cueing, stimulates recognition-based learning and do not align clinical practice. The Very Short Answer Question (VSAQ), an open-ended question with a limited answer, is a good alternative which does not allow for cueing, is authentic and encourages students to study more actively...

Medically assisted reproduction for transgender individuals has been a subject of discussion and debate. While the primary focus used to be whether transgender individuals should have access to assisted reproduction at all, the question has now shifted to what constitutes just access to assisted reproduction for transgender people. It is instructive to compare their access to this care with that of cisgender heterosexual individuals and to critically reflect on the cis- and heteronormative context in which this care takes place...

OBJECTIVE: To investigate whether frail elderly people with atrial fibrillation (AF) who are currently using a vitamin K antagonist (VKA) should be switched to a direct-acting oral anticoagulant (DOAC). DESIGN: Randomized clinical trial. METHODS: 662 frail elderly AF patients were switched to a DOAC, and 661 patients continued their VKA. The primary endpoint was a major or clinically relevant non-major bleeding during 1 year of follow-up. Secondary endpoints included thrombo-embolic events...

Elder abuse is a worldwide problem with serious consequences for individuals and society. The recognition of elder abuse is complex due to a lack of awareness and knowledge. We present a case of a patient with signs of elder abuse. This case concerns a patient who showed signs of neglect and physical abuse as a result of possible derailed informal care provision. The mandatory reporting code on domestic violence of The Royal Dutch Medical Association was followed and measures were taken by the general practitioner...

A good therapeutic relationship leads to better outcomes. In the event of an imminent break in contact, discussing the alliance rupture can be helpful. Optimal use of the countertransference also contributes. Metacommunication can be useful. In this article, some cases illustrating these concepts, are being discussed.