Giorgio Cazzaniga, Francesco Mascadri, Stefano Marletta, Alessandro Caputo, Gabriele Guidi, Giovanni Gambaro, Albino Eccher, Angelo Paolo Dei Tos, Fabio Pagni, Vincenzo L'Imperio
AIM: The digital transformation of the pathology laboratory is being continuously sustained by the introduction of innovative technologies promoting whole slide image (WSI)-based primary diagnosis. Here, we proposed a real-life benchmark of a pathology-dedicated medical monitor for the primary diagnosis of renal biopsies, evaluating the concordance between the 'traditional' microscope and commercial monitors using WSI from different scanners. METHODS: The College of American Pathologists WSI validation guidelines were used on 60 consecutive renal biopsies from three scanners (Aperio, 3DHISTECH and Hamamatsu) using pathology-dedicated medical grade (MG), professional grade (PG) and consumer-off-the-shelf (COTS) monitors, comparing results with the microscope diagnosis after a 2-week washout period...
March 27, 2024: Journal of Clinical Pathology