Shaddy K Saba, Anthony Rodriguez, Daniel L Dickerson, Lynette Mike, Kurt Schweigman, Virginia Arvizu-Sanchez, George Funmaker, Carrie L Johnson, Ryan A Brown, Nipher Malika, Elizabeth J D'Amico
OBJECTIVE: American Indian/Alaska Native (AI/AN) people have high rates of physical pain. Pain is understudied in urban-dwelling, AI/AN emerging adults, a group with unique socio-cultural risk and protective factors. We explore associations between socioeconomic disadvantage, additional socio-cultural factors, and pain among urban AI/AN emerging adults. METHODS: AI/AN participants aged 18-25 (N = 417) were recruited via social media. Regression models tested associations between socioeconomic disadvantage (income and ability to afford healthcare) and pain as well as additional socio-cultural factors (discrimination, historical loss, cultural pride and belonging, visiting tribal lands) and pain...
May 24, 2024: Psychosomatic Medicine
Stephen Gallagher, Ruth Ryan, Irene Cassidy, Wenyi Tang, Anna C Whittaker
OBJECTIVE: Antibody response to vaccination is a powerful paradigm for studying the effects of chronic stress on immune function. In the present study, we used this paradigm to examine the interaction between caregiving (as a type of chronic stress) and sex on the antibody response to a single dose of a COVID-19 vaccination; recent research has called for examination of sex differences on health outcomes among family caregivers. A three-way interaction between caregiving, sex and psychological distress was also examined...
May 16, 2024: Psychosomatic Medicine
Chenyue Ma, Xiaoqin Wang, Scott D Blain, Yafei Tan
OBJECTIVE: In daily life, we must dynamically and flexibly deploy strategies to regulate our emotions, which depends on awareness of emotions and internal bodily signals. Variability in emotion-regulation strategy use may predict fewer negative emotions, especially when people pay more attention to their bodily states-or have greater "interoceptive attention" (IA). Using experience sampling, this study aimed to test whether IA predicts variability in strategy use and whether this variability and IA together predict negative affect...
May 13, 2024: Psychosomatic Medicine
Ali A Weinstein, Robbie C M van Aert, Kiersten Donovan, Lotte Muskens, Willem J Kop
OBJECTIVE: Acute exercise elicits various biobehavioral and psychological responses, but results are mixed with regard to the magnitude of exercise-induced affective reactions. This meta-analysis examines the magnitude of general mood state, anxiety, and depressive symptom responses to acute exercise while exploring exercise protocol characteristics and background health behaviors that may play a role in the affective response. METHODS: A total of 2,770 articles were identified from a MEDLINE/PubMed search and an additional 133 articles from reviews of reference sections...
May 13, 2024: Psychosomatic Medicine
Lisbeth Nielsen, Anna L Marsland, Elissa J Hamlat, Elissa S Epel
The "geroscience hypothesis" posits that slowing the physiological processes of aging would lead to delayed disease onset and longer healthspan and lifespan. This shift from a focus on solely treating existing disease to slowing the aging process is a shift toward prevention, including a focus on risk factors found in the social environment. While geroscience traditionally has focused on the molecular and cellular drivers of biological aging, more fundamental causes of aging may be found in the social exposome - the complex array of human social environmental exposures that shape health and disease...
May 9, 2024: Psychosomatic Medicine
Benjamin W Nelson, Nicholas C Peiper, Kirstin Aschbacher, Valerie L Forman-Hoffman
OBJECTIVES: Multimorbidity or the co-occurrence of multiple health conditions is increasing globally and is associated with significant psychological complications. It is unclear whether digital mental health (DMH) interventions for patients experiencing multimorbidity are effective, particularly given that this patient population faces more treatment resistance. The goal of the current study was to examine the impact of smartphone-delivered DMH interventions for patients presenting with elevated internalizing symptoms that have reported multiple lifetime medical conditions...
May 6, 2024: Psychosomatic Medicine
Jaap Wijnen, Marciano Wilhelmina Henricus Geijselaers, Marc Lucas Pont, Geert van 't Hullenaar, Jessica Van Oosterwijck, Jeroen de Jong
OBJECTIVE: Previous studies evaluating interdisciplinary multimodal interventions for chronic spinal pain often excluded patients with comorbid mental disorders. This study aims to assess the effectiveness of an outpatient secondary care interdisciplinary multimodal integrative healthcare program for individuals experiencing co-occurring chronic spinal pain and mental disorders. METHODS: Participants were 944 patients with chronic spinal pain and comorbid mental disorders...
May 1, 2024: Psychosomatic Medicine
Alexander H J Sahm, Michael Witthöft, Josef Bailer, Daniela Mier
OBJECTIVE: In clinical practice, persistent somatic symptoms are regularly explained using a cognitive-behavioral model (CBM). In the CBM, predisposing, perpetuating, and precipitating factors are assumed to interact and to cause the onset and endurance of somatic symptoms. However, these models are rarely investigated in their entirety. METHODS: We conducted an online-survey during the Corona pandemic. 2,114 participants from the general German population completed questionnaires that measured different factors of the CBM...
April 26, 2024: Psychosomatic Medicine
E Lydia Wu-Chung, Luis D Medina, Jensine Paoletti-Hatcher, Vincent Lai, Jennifer M Stinson, Itee Mahant, Paul E Schulz, Cobi J Heijnen, Christopher P Fagundes
OBJECTIVE: Chronic stress adversely affects mental and physical well-being. However, health outcomes vary among people experiencing the same stressor. Individual differences in physical and emotional well-being may depend on mitochondrial biology, as energy production is crucial for stress regulation. This study investigated whether mitochondrial respiratory capacity corresponds to individual differences in dementia spousal caregivers' mental and physical health. METHODS: Spousal caregivers of individuals with Alzheimer's disease and related dementias (N = 102, mean age = 71, 78% female, 83% White) provided peripheral blood samples and completed self-report questionnaires on quality of life, caregiver burden, and a 7-day affect scale...
April 26, 2024: Psychosomatic Medicine
Stephan Frisch, Steffen Walter, Vanessa Rebhann, Sascha Gruss, Daniela Geisel, Karl-Jürgen Bär, Harald Gündel, Richard D Lane, Ryan Smith
OBJECTIVE: The influence of unconscious emotional processes on pain remains poorly understood. The present study tested whether cues to forgotten unpleasant images might amplify pain (i.e., in the absence of conscious recall). METHODS: 72 healthy female adults (19 to 34 years) performed an adapted Think/No-think paradigm (T/NT) using 72 combinations of neutral face images (cues) paired with 36 neutral & 36 unpleasant images. After completion of the T/NT task, cues associated with forgotten neutral or unpleasant images were identified...
April 26, 2024: Psychosomatic Medicine
Houtan Totonchi Afshar, Joel N Fishbein, Erica J Martinez, Gage M Chu, Mohammad A Shenasa, Dhakshin Ramanathan, Matthew S Herbert
OBJECTIVE: Major depressive disorder (MDD) and chronic pain are highly comorbid and bidirectionally related. Repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex is effective in treating MDD, but additional research is needed to determine if chronic pain interferes with rTMS for MDD. METHODS: Participants were 124 veterans (Mage = 49.14, SD = 13.83) scheduled for 30 sessions of rTMS across six weeks. Depression severity was monitored weekly using the Patient Health Questionnaire-9...
April 26, 2024: Psychosomatic Medicine
Kasra Moazzami, Ambar Kulshreshtha, Matthew Gold, Alireza Rahbar, Felicia Goldstein, Amit J Shah, J Douglas Bremner, Viola Vaccarino, Arshed A Quyyumi
OBJECTIVE: People with coronary artery disease (CAD) are at higher risk of cognitive impairment than those without CAD. Psychological stress is a risk factor for both conditions and assessing the hemodynamic reactivity to mental stress could explain the link between stress and cognitive function. METHODS: Individuals with stable CAD from two prospective cohort studies were included. All individuals underwent acute mental stress testing, as well as conventional stress testing...
April 16, 2024: Psychosomatic Medicine
Pankaja Desai, Ted K S Ng, Kristin R Krueger, Robert S Wilson, Denis A Evans, Kumar B Rajan
INTRODUCTION: There is a substantial gap in knowledge regarding how perceived stress may influence the relationship between serum-measured biomarkers for Alzheimer's disease and cognitive decline. METHODS: This study consists of 1,118 older adult participants from the Chicago Health and Aging Project (CHAP) (60% Black participants and 63% female participants). Linear mixed effects regression models were conducted to examine the role of perceived stress in the association between three blood biomarkers: total tau (t-tau), glial fibrillary acid protein (GFAP), and neurofilament light chain (NfL) on global cognitive decline...
April 16, 2024: Psychosomatic Medicine
Tara M Petzke, Michael Witthöft
OBJECTIVE: People with functional somatic symptoms have difficulties in various stages of the emotion regulation (ER) process (1). As an adaptive and flexible use of ER strategies is a core tenet of emotional health, having difficulties in this area is often assumed to be the key mechanism behind functional somatic symptoms. Following a dimensional population-based sampling approach, we investigated emotion regulation abilities across a broad range of people and tested possible associations with somatic symptom reporting, habitual ER use as well as various subclinical constructs (such as alexithymia and anxiety)...
April 11, 2024: Psychosomatic Medicine
Rosemarie de la Rosa, Austin Le, Stephanie Holm, Morgan Ye, Nicole R Bush, Danielle Hessler, Kadiatou Koita, Monica Bucci, Dayna Long, Neeta Thakur
OBJECTIVE: Examine the independent associations and interaction between early-life adversity and residential ambient air pollution exposure on relative buccal telomere length (rBTL). METHODS: Experiences of abuse, neglect, household challenges, and related life events were identified in a cross-sectional sample of children ages 1-11 years (n = 197) using the 17-item Pediatric ACEs and Related Life Event Screener (PEARLS) tool. The PEARLS tool was analyzed both as a total score and across established domains (Maltreatment, Household Challenges, and Social Context)...
April 9, 2024: Psychosomatic Medicine
Thomas E Fuller-Rowell, Megan M Zeringue, Ekjyot K Saini, Tiffany Yip, Mona El-Sheikh
OBJECTIVE: An emerging literature suggests that sleep may play an important role in moderating the association between discrimination and mental health problems among adolescents. However, few if any studies have considered this topic among adults. Addressing this knowledge gap, the current study examined multiple sleep parameters as moderating variables in the association between discrimination and mental health problems among adults. METHODS: Participants were 874 adults residing in small towns and semi-rural contexts within the Southeastern region of the United States (Mage = 41 years, SD = 7; 57% female; 31% Black, 69% White; 52% income-to-needs <2)...
March 25, 2024: Psychosomatic Medicine
Tereza Serranová, Matěj Slovák, Zuzana Forejtová, Tomáš Sieger, Petr Dušek, Barbora Srpová, Kateřina Mrázová, Evžen Růžička, Karel Šonka, Alberto J Espay, Petra Nytrová
OBJECTIVE: The role of inflammation and neuroimmune mechanisms, which have been documented in various neuropsychiatric disorders including the seizure subtype of functional neurological disorder, remains unclear in functional movement disorders (FMD). To explore these mechanisms, we analyzed selected inflammatory markers in cerebrospinal fluid (CSF) in patients with FMD. METHODS: We compared CSF markers in 26 patients with clinically established FMD (20 females; mean (SD) age 43...
March 25, 2024: Psychosomatic Medicine
Rebeca Alvarado Harris, Jamie Crandell, Jacquelyn Y Taylor, Hudson P Santos
OBJECTIVE: Immigrant Latinas, particularly of Mexican descent, initially achieve healthy perinatal outcomes. Although this advantage wears off across generations in the United States (US), the early life psychosocial mechanisms that may initiate a cascade of biological vulnerabilities remain elusive. The current investigation aims to understand the extent to which childhood experiences of racism may contribute to elevated levels of C-Reactive Protein (CRP), an early indicator of cardiometabolic risk, during the first postpartum year...
March 25, 2024: Psychosomatic Medicine
Arielle A J Scoglio, Karmel W Choi, Kristen Nishimi, Laura Sampson, Karestan Koenen, Andrea L Roberts, Shaili Jha, Laura D Kubzansky
OBJECTIVE: Prior work suggests psychological resilience to trauma may protect not only mental but also physical health. This study examined the relationship of pre-pandemic psychological resilience to lifetime trauma with self-reported COVID-19 infection and symptoms during the early years of the COVID-19 pandemic. METHODS: Data are from 18,670 longitudinal cohort participants in the Nurses' Health Study II. Based on prior evidence that trauma and subsequent distress can increase infection risk and severity, and that psychological assets may offset this risk, we hypothesized higher versus lower psychological resilience to prior trauma would be associated with lower risk for COVID-19 infection...
March 25, 2024: Psychosomatic Medicine
Eunjin Lee Tracy, Brian N Chin, H Matthew Lehrer, Brant P Hasler, Mark C Thomas, Stephen Smagula, Sarah Kimutis, Martica H Hall, Daniel J Buysse
OBJECTIVE: Stability in the timing of key daily routine behaviors such as working/doing housework, sleeping, eating, and engaging in social interactions (i.e., behavioral-social rhythms) contributes to health. This study examined whether behavioral-social rhythms were associated with CVD risk factors in retired night shift workers and retired day workers and explored whether past night shift work exposure moderated this association. METHODS: 154 retired older adults participated in this study...
March 25, 2024: Psychosomatic Medicine
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