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Psychosomatic Medicine

Katherine A Duggan, J Richard Jennings, Karen A Matthews
OBJECTIVE: Conscientiousness predicts better psychological resources as well as lower cardiovascular mortality and lower metabolic syndrome (MetS) risk. However, the benefits of conscientiousness might be amplified, disabled, or reversed in disadvantaged groups. This study is the first to test these competing hypotheses for prospective associations between adolescent conscientiousness and adult psychological resources and MetS. METHOD: Participants were 220 men (54...
March 7, 2019: Psychosomatic Medicine
Marlene S Williams, Roy C Ziegelstein, Una D McCann, Neda F Gould, Tamara Ashvetiya, Dhananjay Vaidya
OBJECTIVE: Depression in patients with cardiovascular disease is associated with increased risk of adverse clinical outcomes. Investigators have searched for potential biobehavioral explanations for this increased risk. Platelet activation and response to serotonin is an attractive potential mechanism. Our objective was to examine platelet serotonin signaling in a group of patients with coronary artery disease and comorbid depression to define the relationship between platelet serotonin signaling and cardiovascular complications...
March 7, 2019: Psychosomatic Medicine
Christoph Herrmann-Lingen, Jörg Melzer, Dirk von Boetticher
OBJECTIVE: Social relationships play an important role in human health and disease processes, and the field of psychosomatic medicine currently integrates social factors in its theoretical models and clinical interventions. This article provides a historical perspective on the field of psychosomatic medicine in the United States and examines the extent to which early American psychosomatic medicine incorporated the impact of social relationships on health and disease outcomes. METHODS: We searched pubmed across all issues of Psychosomatic Medicine for key words related to emotions vs...
February 19, 2019: Psychosomatic Medicine
Tené T Lewis, Rachel Lampert, Domonique Charles, Stuart Katz
OBJECTIVE: Several researchers have argued that racism-related stressors play an important role in adverse cardiovascular outcomes among African-American women. However, studies have primarily focused on experiences of racism; thus, the role of expectations of racism is insufficiently understood. The current proof-of-concept study was designed to examine associations among expectations of racism, self-reported experiences of racism, and carotid intima-media thickness (IMT), a marker of cardiovascular risk, in African-American women...
February 13, 2019: Psychosomatic Medicine
David C Houghton, Thomas W Uhde, Jeffrey J Borckardt, Bernadette M Cortese
OBJECTIVE: Enhanced odor sensitivity is a phenomenon that potentially underlies conditions such as multiple chemical sensitivity (MCS). Currently, there are no treatments that have been shown to effectively decrease odor sensitivity. Given similarities of odor hypersensitivity/MCS to pain sensitization disorders such as fibromyalgia, there may be a potential for interventions that improve pain tolerance to modulate odor sensitivity. METHODS: This exploratory study randomized 72 healthy community adult volunteers to receive one of six treatments in between two assessments of thermal pain tolerance and odor threshold...
February 12, 2019: Psychosomatic Medicine
Puja K Mehta, Aneesha Thobani, Viola Vaccarino
Symptomatic individuals suspected of having myocardial ischemia often have no obstructive atherosclerotic narrowing of epicardial coronary arteries. Abnormal coronary vascular reactivity, and in particular, coronary artery vasospasm (CAS), may be an explanation in a subset of these patients. Psychological factors play an important role in ischemic heart disease, but their role in CAS is not clear; autonomic dysfunction and increased inflammation are two prevailing pathophysiological mechanisms implicated in abnormal coronary reactivity resulting from mental health conditions...
February 8, 2019: Psychosomatic Medicine
Bert N Uchino, Joshua Landvetter, Sierra Cronan, Emily Scott, Michael Papadakis, Timothy W Smith, Jos A Bosch, Samantha Joel
OBJECTIVE: Despite its simplicity, single-item measures of self-rated health have been associated with mortality independent of objective health conditions. However, little is known about the mechanisms potentially responsible for such associations. This study tested the association between self-rated heath and inflammatory markers as biological pathways, and whether sleep quality and/or depression statistically mediated such links. METHOD: Eighty-six heterosexual married couples completed a standard measure of self-rated health, the CES-Depression scale, and the Pittsburgh Sleep Quality Index...
February 8, 2019: Psychosomatic Medicine
Tatjana Stadnitski, Beate Wild
OBJECTIVES: Longitudinal data allow for conclusions about the temporal order of events and interactional dynamics between several processes. The aim of this article is to provide a concise and pragmatic description of time series analyses (TSA) of patient samples with numerous (or daily) repeated biological, behavioral, or psychological measurements. In addition, the article demonstrates how to implement the described analyses with the software R. METHODS: To illustrate the concrete application of the time series method we use two case-series of patients with anorexia nervosa (AN)...
February 5, 2019: Psychosomatic Medicine
Joseph Firth, Wolfgang Marx, Sarah Dash, Rebekah Carney, Scott B Teasdale, Marco Solmi, Brendon Stubbs, Felipe B Schuch, André F Carvalho, Felice Jacka, Jerome Sarris
OBJECTIVE: Poor diet can be detrimental to mental health. However, the overall evidence for the effects of dietary interventions on mood and mental well-being has yet to be assessed. We conducted a systematic review and meta-analysis examining effects of dietary interventions on symptoms of depression and anxiety. METHOD: Major electronic databases were searched through March 2018 for all randomized controlled trials (RCTs) of dietary interventions reporting changes in symptoms of depression and/or anxiety in clinical and non-clinical populations...
February 5, 2019: Psychosomatic Medicine
Robyn Thom, David A Silbersweig, Robert J Boland
Major Depression, as well as other depressive disorders, are commonly comorbid with other medical illnesses, particularly chronic and systemic medical illnesses. The cooccurrence of the disorders is so common that it challenges our notions of the meaning of comorbidity and our desire to neatly separate psychiatric and medical illnesses. The overlap between symptoms of physical illness and the neurovegetative symptoms of major depression and the initial normative emotional response to physical illness add to the challenge of accurate diagnosis and timely treatment of depression in the medically ill...
February 1, 2019: Psychosomatic Medicine
Elena Salmoirago-Blotcher, Kathleen M Hovey, Cristopher A Andrews, Matthew Allison, Robert L Brunner, Nathalie L Denburg, Charles Eaton, Lorena Garcia, Shawnita M Sealy-Jefferson, Oleg Zaslavsky, Joseph Kang, Lenny López, Stephen G Post, Hilary Tindle, Sylvia Wassertheil-Smoller
OBJECTIVE: Psychological traits such as optimism and hostility affect coronary heart disease (CHD) risk, but mechanisms for this association are unclear. We hypothesized that optimism and hostility may affect CHD risk via changes in heart rate variability (HRV). METHODS: We conducted a longitudinal analysis using data from the Women's Health Initiative Myocardial Ischemia and Migraine Study. Participants underwent 24-hour ambulatory ECG monitoring 3 years after enrollment...
January 24, 2019: Psychosomatic Medicine
J David Creswell, Emily K Lindsay, Daniella K Villalba, Brian Chin
OBJECTIVE: There has been substantial research and public interest in mindfulness interventions, biological pathways, and health over the past two decades. This article reviews recent developments in understanding relationships between mindfulness interventions and physical health. METHODS: A selective review was conducted with the goal of synthesizing conceptual and empirical relationships between mindfulness interventions and physical health outcomes. RESULTS: Initial randomized controlled trials (RCTs) in this area suggest that mindfulness interventions can improve pain management outcomes among chronic pain populations, and there is preliminary evidence for mindfulness interventions improving specific stress-related disease outcomes in some patient populations (i...
January 23, 2019: Psychosomatic Medicine
Pratik Pimple, Muhammad Hammadah, Kobina Wilmot, Ronnie Ramadan, Ibhar Al Mheid, Oleksiy Levantsevych, Samaah Sullivan, Bruno B Lima, Jeong Hwan Kim, Ernest V Garcia, Jonathon Nye, Amit J Shah, Laura Ward, Paolo Raggi, J Douglas Bremner, John Hanfelt, Tené T Lewis, Arshed A Quyyumi, Viola Vaccarino
OBJECTIVES: Mental stress-induced myocardial ischemia (MSIMI) is a frequent phenomenon in patients with coronary artery disease (CAD). The link between an integrated measure of chronic psychosocial distress and MSIMI, and whether it differs by sex, has not been examined before. METHODS: We used latent class analysis (LCA) to derive a composite measure of psychosocial distress integrating scales of depression, posttraumatic stress, anxiety, anger, hostility, and perceived-stress in 665 individuals with stable CAD...
January 23, 2019: Psychosomatic Medicine
Ming-Yow Hung, Chun-Tai Mao, Ming-Jui Hung, Jiunn-Kae Wang, Hsin-Chien Lee, Chi-Tai Yeh, Patrick Hu, Tien-Hsing Chen, Nen-Chung Chang
OBJECTIVE: Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished. METHODS: Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching (PSM), we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during the period 2000-2012...
January 15, 2019: Psychosomatic Medicine
Amie M Gordon, Kareena Del Rosario, Abdiel J Flores, Wendy Berry Mendes, Aric A Prather
OBJECTIVE: This set of studies examines the bi-directional links between social rejection and sleep, a ubiquitous and increasingly problematic health behavior. METHODS: In Study 1, a multi-day field experiment, 43 participants completed a neutral task just prior to sleep on night 1 and a social rejection task on night 2. Objective and subjective sleep, post-rejection affect, and physiological responses were measured. In Study 2, 338 participants reported typical sleep quality prior to coming to the laboratory where they received social rejection or social acceptance feedback from a stranger...
January 10, 2019: Psychosomatic Medicine
Linda C Gallo, Scott C Roesch, Julia I Bravin, Kimberly L Savin, Krista Perreira, Mercedes R Carnethon, Alan M Delamater, Christian R Salazar, Maria Lopez-Gurrola, Carmen R Isasi
OBJECTIVE: We examined associations among socioeconomic adversity, social resources, and allostatic load in Hispanic/Latino youth, who are at high risk for obesity and related cardiometabolic risks. METHODS: Participants were N=1343 Hispanic/Latino youth (51% male; ages 8-16 years) offspring of Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants. Between 2012-2014, youth underwent a fasting blood draw and anthropometric assessment, and youth and their enrolled caregivers provided social and demographic information...
January 10, 2019: Psychosomatic Medicine
Allison J Carroll, Mark D Huffman, Lihui Zhao, David R Jacobs, Jesse C Stewart, Catarina I Kiefe, Kiang Liu, Brian Hitsman
OBJECTIVE: To evaluate associations between 15-year trajectories of co-occurring depressive symptoms and smoking with biomarkers of cardiovascular disease at Year 15. METHODS: In the Coronary Artery Risk Development in Young Adults (CARDIA) study, we modeled trajectories of depressive symptoms (Center for Epidemiologic Studies - Depression scale: CES-D) and smoking (cigarettes per day: CPD) among 3,614 adults followed from Year 0 (ages 18-30) through Year 15 (ages 33-45)...
January 8, 2019: Psychosomatic Medicine
Andrea Wyssen, Lao Junpeng, Helen Rodger, Nadine Humbel, Julia Lennertz, Kathrin Schuck, Bettina Isenschmid, Gabriella Milos, Stephan Trier, Katherina Whinyates, Hans-Jörg Assion, Bianca Ueberberg, Judith Müller, Benedikt Klauke, Tobias Teismann, Jürgen Margraf, Georg Juckel, Christian Kossmann, Silvia Schneider, Roberto Caldara, Simone Munsch
OBJECTIVE: Impairments in facial emotion recognition are an underlying factor of deficits in emotion regulation and interpersonal difficulties in mental disorders, and are evident in eating disorders (EDs). METHODS: We used a computerized psychophysical paradigm to manipulate parametrically the quantity of signal in facial expressions of emotion (QUEST threshold seeking algorithm). This was used to measure emotion recognition in 311 adult women (anorexia nervosa (AN,n=61), bulimia nervosa (BN,n=58), healthy controls (HC,n=130) and mixed mental disorders (mixed,n=59))...
January 4, 2019: Psychosomatic Medicine
Madeline H Meier, Dustin Pardini, Jordan Beardslee, Karen A Matthews
OBJECTIVE: This study tested longitudinal associations between cannabis use and cardiometabolic risk factors that underlie the development of cardiovascular diseases. METHODS: Participants were men from the youngest cohort of the Pittsburgh Youth Study who were followed prospectively from approximately age 7 to 32 (n=253). Frequency of cannabis use was assessed yearly from ~ages 12-20 and again at ~ages 26, 29, and 32. The following cardiometabolic risk factors were assessed during a laboratory visit at age ~32: BMI, WHR, HDL and LDL cholesterol, triglycerides, fasting glucose, HOMA-IR, blood pressure, interleukin 6, and C-reactive protein...
December 27, 2018: Psychosomatic Medicine
Gwen Tindula, Robert B Gunier, Julianna Deardorff, Kelly Nabaglo, Alan Hubbard, Karen Huen, Brenda Eskenazi, Nina Holland
OBJECTIVE: Little is known about the impact of the home environment on biomarkers of obesity, such as adipokines, in children. In this study, we examined the relationship of maternal depressive symptoms and potentially protective social factors, including maternal support and the home learning environment, with BMI and adipokines. METHODS: Data were obtained from 326 Mexican-American participants from the CHAMACOS cohort. Plasma adipokine levels were assessed in 326 children by enzyme-linked immunoassay at birth or ages 5, 9, or 14...
December 19, 2018: Psychosomatic Medicine
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