journal
https://read.qxmd.com/read/38459693/molecular-rotors-of-naphthalimide-and-benzodithiophene-as-effective-solvent-polarity-probes-temperature-sensors-and-for-g-c-3-n-4-sensitization
#21
JOURNAL ARTICLE
Anita Kumari, Sushil Sharma, Sanchita Sengupta
Acceptor-donor-acceptor (A-D-A) molecular rotors have drawn substantial attention for their applications in monitoring temperature variations within cellular microenvironments, biomimetic photocatalysis, and bioimaging. In this study, we have synthesized two novel rotor molecules, NBN1 and NBN2, by incorporating benzodithiophene (BDT) as the donor core and naphthalic anhydride/naphthalimide (NA/NI) moieties as acceptors using Pd-catalyzed Stille coupling reactions. These molecules exhibited distinct charge transfer (CT) behavior in both their absorption and emission spectra and displayed prominent emission solvatochromism...
March 8, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38456366/potential-of-using-medicinal-plant-extracts-as-photosensitizers-for-antimicrobial-photodynamic-therapy
#22
JOURNAL ARTICLE
Aliaksandr V Mikulich, Vitaly Yu Plavskii, Antonina I Tretyakova, Raman K Nahorny, Andrey N Sobchuk, Natalia V Dudchik, Olga A Emeliyanova, Anastasia I Zhabrouskaya, Ludmila G Plavskaya, Tatsiana S Ananich, Olga N Dudinova, Ihar A Leusenka, Sergey V Yakimchuk, Alexei D Svechko, Tran Quoc Tien, Quang Cong Tong, Thanh Phuong Nguyen
Antimicrobial photodynamic therapy (APDT) is a promising approach to overcome antimicrobial resistance. However, for widespread implementation of this approach, approved photosensitizers are needed. In this study, we used commercially available preparations (Calendulae officinalis floridis extract, Chamomillae recutitae floridis extract, Achillea millefolii herbae extract; Hypericum perforatum extract; Eucalyptus viminalis folia extract) as photosensitizers for inactivation of gram-negative (Pseudomonas aeruginosa) and gram-positive (Staphylococcus aureus) bacteria...
March 8, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38445797/application-of-tnb-in-dual-photo-controlled-release-of-phenamacril-imidacloprid-and-imidacloprid-synergist
#23
JOURNAL ARTICLE
Qi Yin, Wen Fu, Xinyue Hu, Zhiping Xu, Zhong Li, Xusheng Shao
Pesticides can improve crops' yield and quality, but unreasonable applications of pesticides lead to waste of pesticides which are further accumulated in the environment and threaten human health. Developing the release of controlled drugs can improve the utilization rate of pesticides. Among these methods, light-controlled release is a new technology of controlled release, which can realize spatiotemporal delivery of drugs by light. Four compounds, named Imidacloprid-Thioacetal o-nitrobenzyl-Phenamacril (IMI-TNB-PHE), Imidacloprid-Thioacetal o-nitrobenzyl- Imidacloprid (IMI-TNB-IMI), Phenamacril-Thioacetal o-nitrobenzyl-Phenamacril (PHE-TNB-PHE), and Imidacloprid-Thioacetal o-nitrobenzyl-Imidacloprid Synergist (IMI-TNB-IMISYN), were designed and synthesized by connecting thioacetal o-nitrobenzyl (TNB) with pesticides TNB displaying simple and efficient optical properties in this work...
March 6, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38445720/photoprotective-effect-of-topical-treatment-with-lopezia-racemosa-extract-against-deleterious-uvb-irradiation-effects-in-the-skin-of-hairless-mice
#24
JOURNAL ARTICLE
Nolasco Ontiveros Erick, Espinosa González Adriana Montserrat, Estrella Parra Edgar Antonio, Serrano Parrales Rocío, López Urrutia Eduardo, García Castillo Verónica, Rodríguez-Sosa Miriam, Juárez-Avelar Imelda, Benítez Flores José Del Carmen, Rivera Cabrera José Cruz, Hernández Delgado Claudia Tzasna, García Bores Ana María, Avila Acevedo José Guillermo
Lopezia racemosa is known as a "mosquito flower or perlilla." It is commonly found in corn crops. In traditional Mexican medicine, this plant is used to treat stomach cancer and urinary tract infections. Likewise, compounds and extracts isolated from plants have shown cytotoxic and anti-inflammatory effects. The objective of this study was to evaluate the photochemoprotective effect of topical treatment with the methanolic extract of L. racemosa (MELR) as a photochemoprotective agent against the harmful effects of UV irradiation (UVR) on a bacterial model and hairless mice...
March 6, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38433456/the-acid-sphingomyelinase-inhibitor-imipramine-enhances-the-release-of-uv-photoproduct-containing-dna-in-small-extracellular-vesicles-in-uvb-irradiated-human-skin
#25
JOURNAL ARTICLE
M Alexandra Carpenter, Anita Thyagarajan, Madison Owens, Risha Annamraju, Christina B Borchers, Jeffrey B Travers, Michael G Kemp
Nucleic acids, lipids, and other cell components can be found within different types of extracellular vesicles (EVs), which include apoptotic bodies (ABs), large extracellular vesicles (LEVs), and small extracellular vesicles (SEVs). Release of LEVs from cells can be reduced by genetic or pharmacological inhibition of the enzyme acid sphinogomyelinase (aSMase), and indeed several studies have demonstrated a role for the clinically approved aSMase inhibitor imipramine in blocking LEV release, including in response to UVB exposure...
March 3, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38433310/mitochondrial-targeting-improves-the-selectivity-of-singlet-oxygen-cleavable-prodrugs-in-nmibc-treatment
#26
JOURNAL ARTICLE
Kazi Md Mahabubur Rahman, Ganesh Bist, Soniya Kumbham, Barbara A Foster, Sukyung Woo, Youngjae You
Mitochondria play an essential role in cancer treatment by providing apoptotic signals. Hexyl aminolevulinate, an FDA-approved diagnosis for non-muscle invasive bladder cancer, induces the production of protoporphyrin IX (PpIX) preferentially by mitochondria in cancer cells. Photosensitizer PpIX upon illumination can release active chemotherapy drugs from singlet oxygen-activatable prodrugs. Prodrugs placed close enough to PpIX formed in mitochondria can improve the antitumor efficiency of PpIX-PDT. The preferred uptake of prodrugs by cancer cells and tumors can further enhance the selective damage of cancer cells over non-cancer cells and surrounding normal tissues...
March 3, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38419115/dansyl-tagged-xanthate-ester-as-a-capping-agent-to-synthesize-fluorescent-silver-nanoparticles-with-binding-affinity-toward-serum-albumin
#27
JOURNAL ARTICLE
Debashis Barik, Chandrasekhar Pidikaka, Mintu Porel
Developing multifunctional nanomaterials with distinct photochemical properties, such as high quantum yield, improved photostability, and good biocompatibility is critical for a wide range of biomedical applications. Motivated by this, we designed and synthesized a dansyl-tagged xanthate-based capping agent (DX) for the synthesis of fluorescent silver nanoparticles (AgNPs). The capping agent DX was characterized by 1 H and 13 C-NMR, LC-MS, and FT-IR. The synthesized DX-capped fluorescent AgNPs were thoroughly characterized by UV-visible spectroscopy, fluorescence spectroscopy, field emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), dynamic light scattering (DLS), and zeta potential...
February 28, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38396365/antiradical-capacity-assay-for-hydrophobic-substances-using-hemin-catalyzed-luminol-chemiluminescence-in-cationic-micelles
#28
JOURNAL ARTICLE
Cerize S Santos, Marcos P O Lemos, Larissa M Betschart, Wilhelm J Baader
Antioxidant substances which can diminish the steady-state concentration of free radicals in vivo are important in the human dietary to diminish the deleterious effects of oxidative stress. As the potential of certain substances as antioxidants is difficult to be verified in vivo, simple chemical in vitro assays which test the potential of substances as antioxidants are of great importance for the screening of new antioxidants. These assays measure the capacity of a substance to suppress free radicals...
February 23, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38385897/fluorescent-styrenes-for-mitochondrial-imaging-and-viscosity-sensing
#29
JOURNAL ARTICLE
Deepmala Singh, Mohini Ghorpade, Ramprasad Regar, Mayeul Collot, Virupakshi Soppina, Sriram Kanvah
Fluorophores bearing cationic pendants, such as the pyridinium group, tend to preferentially accumulate in mitochondria, whereas those with pentafluorophenyl groups display a distinct affinity for the endoplasmic reticulum. In this study, we designed fluorophores incorporating pyridinium and pentafluorophenyl pendants and examined their impact on sub-cellular localization. Remarkably, the fluorophores exhibited a notable propensity for the mitochondrial membrane. Furthermore, these fluorophores revealed dual functionality by facilitating the detection of viscosity changes within the sub-cellular environment and serving as heavy-atom-free photosensitizers...
February 22, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38356286/reconciling-td-dft-and-caspt2-electronic-structure-methods-for-describing-the-photophysics-of-dna
#30
JOURNAL ARTICLE
Vishal Kumar Jaiswal, Mario Taddei, Daniel R Nascimento, Marco Garavelli, Irene Conti, Artur Nenov
Time-dependent density functional theory (TD-DFT) and multiconfigurational second-order perturbation theory (CASPT2) are two of the most widely used methods to investigate photoinduced dynamics in DNA-based systems. These methods sometimes give diverse dynamics in physiological environments usually modeled by quantum mechanics/molecular mechanics (QM/MM) protocol. In this work, we demonstrate for the uridine test case that the underlying topology of the potential energy surfaces of electronic states involved in photoinduced relaxation is similar in both electronic structure methods...
February 14, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38348536/blue-light-impairs-the-repair-of-uvb-induced-pyrimidine-dimers-in-a-human-skin-model
#31
JOURNAL ARTICLE
Thierry Douki, Daniel Bacqueville, Carine Jacques, Camille Geniès, Nicolas Roullet, Sandrine Bessou-Touya, Hélène Duplan
In recent years, interest is growing in the biological cutaneous effects of high-energy visible light (400-450 nm). In the present study, we explored the impact of blue light (BL) on the repair of pyrimidine dimers, the major class of premutagenic DNA damage induced by exposure to sunlight. We unambiguously demonstrate that the exposure of in vitro reconstructed human epidermis to environmentally relevant doses of BL strongly decreases the rate of repair of cyclobutane pyrimidine dimers and pyrimidine (6-4) pyrimidone photoproducts induced by a subsequent UVB irradiation...
February 13, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38339836/associations-between-sun-exposure-skin-ph-and-epidermal-permeability-in-pregnancy-a-longitudinal-observational-study
#32
JOURNAL ARTICLE
Rachel Stevens, Shelley Gorman, Diana Arabiat, Claus T Christophersen, Debra J Palmer
Little is known about how sun exposure may affect the maternal skin barrier during pregnancy when many hormonal and physiological changes occur. In this longitudinal observational study, 50 pregnant women were recruited at 18-24 weeks' gestation, 25 in summer-autumn, and 25 in winter-spring. At three time points in pregnancy at 18-24, 28-30, and 36-38 weeks' gestation, participants completed a validated sun exposure questionnaire and had skin permeability and surface pH measured on the volar forearm...
February 9, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38337181/protective-effect-of-isoquercitrin-on-uvb-induced-injury-in-hacat-cells-and-mice-skin-through-anti-inflammatory-antioxidant-and-regulation-of-mapk-and-jak2-stat3-pathways
#33
JOURNAL ARTICLE
Yingyan Li, Yunge Ma, Yike Yao, Guohua Ru, Chong Lan, Liyan Li, Tao Huang
Natural products are favored in the study of skin photodamage protection recently. Isoquercetin, namely 3-O-glucoside of quercetin, can be isolated from various plant species. In present research, the protective effect of isoquercitrin on UVB-induced injury in cells and mice skin were investigated. Our study reveals that 400 μM of isoquercitrin exhibits the best viability on UVB-irradiated HaCaT cells, and beneficial effects against oxidative stress UVB-induced in skin tissue by decreasing the levels of reactive oxygen species (ROS) and malondialdehyde (MDA), and simultaneously enhancing the activity of superoxide dismutase (SOD)...
February 9, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38317517/transcriptome-analysis-in-mouse-skin-after-exposure-to-ultraviolet-radiation-from-a-canopy-sunbed
#34
JOURNAL ARTICLE
Sami S Qutob, Samantha P M Roesch, Sandy Smiley, Pascale Bellier, Andrew Williams, Kate B Cook, Matthew J Meier, Andrea Rowan-Carroll, Carole L Yauk, James P McNamee
Exposure to ultraviolet radiation (UV-R), from both natural and artificial tanning, heightens the risk of skin cancer by inducing molecular changes in cells and tissues. Despite established transcriptional alterations at a molecular level due to UV-R exposure, uncertainties persist regarding UV radiation characterization and subsequent genomic changes. Our study aimed to mechanistically explore dose- and time-dependent gene expression changes, that may drive short-term (e.g., sunburn) and long-term actinic (e...
February 5, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38314442/interactions-of-drosophila-cryptochrome
#35
JOURNAL ARTICLE
Gozde Ozcelik, Mehmet Serdar Koca, Buket Sunbul, Fatma Yilmaz-Atay, Feride Demirhan, Busra Tiryaki, Kevser Cilenk, Saba Selvi, Nuri Ozturk
In this study, we investigate the intricate regulatory mechanisms underlying the circadian clock in Drosophila, focusing on the light-induced conformational changes in the cryptochrome (DmCry). Upon light exposure, DmCry undergoes conformational changes that prompt its binding to Timeless and Jetlag proteins, initiating a cascade crucial for the starting of a new circadian cycle. DmCry is subsequently degraded, contributing to the desensitization of the resetting mechanism. The transient and short-lived nature of DmCry protein-protein interactions (PPIs), leading to DmCry degradation within an hour of light exposure, presents a challenge for comprehensive exploration...
February 5, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38312100/excited-state-properties-of-5-fluoro-4-thiouridine-derivative-%C3%A2
#36
JOURNAL ARTICLE
Rin Sato, Yoshino Yamada, Wataru Kashihara, Tatsuya Nishihara, Kazuhito Tanabe, Yao-Zhong Xu, Tadashi Suzuki
The excited state properties of thionated 5-fluorouridine (2',3',5'-tri-O-acetyl-5-fluoro-4-thiouridine; ta5F4TUrd), synthesized with Lawesson's reagent, have been intensively investigated with nanosecond transient absorption spectroscopy, time-resolved thermal lensing, near-infrared emission, and quantum chemical calculation. The intrinsic triplet lifetime of ta5F4TUrd was determined to be <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"> <mml:semantics><mml:mrow><mml:mn>4.2</mml:mn> <mml:mo>±</mml:mo> <mml:mn>0...
February 5, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38310633/treatment-of-nonmelanoma-skin-cancer-with-pro-differentiation-agents-and-photodynamic-therapy-preclinical-and-clinical-studies-review
#37
REVIEW
Sanjay Anand, Tayyaba Hasan, Edward V Maytin
Photodynamic therapy (PDT) is a nonscarring cancer treatment in which a pro-drug (5-aminolevulinic acid, ALA) is applied, converted into a photosensitizer (protoporphyrin IX, PpIX) which is then activated by visible light. ALA-PDT is now popular for treating nonmelanoma skin cancer (NMSC), but can be ineffective for larger skin tumors, mainly due to inadequate production of PpIX. Work over the past two decades has shown that differentiation-promoting agents, including methotrexate (MTX), 5-fluorouracil (5FU) and vitamin D (Vit D) can be combined with ALA-PDT as neoadjuvants to promote tumor-specific accumulation of PpIX, enhance tumor-selective cell death, and improve therapeutic outcome...
February 4, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38299663/modulation-of-excited-state-intramolecular-proton-transfer-and-intramolecular-charge-transfer-pathways-of%C3%A2-symmetrical-azines-through-micellar-medium
#38
JOURNAL ARTICLE
Ramalingam Suhasini, Ulagammal Venkatasubramanian, Viruthachalam Thiagarajan
The photophysical studies of fluorescent probes in micellar medium can give a better insight about their interaction with biological membranes. This study attempts to access the photophysical properties of the dual emitting azine based probe diethylamino salicylidene azine dimer (DEASAD) in micellar media. DEASAD showed dual charge transfer emission due to the presence of open enol (480 nm) and closed enol (510 nm) forms in polar protic solvents. Upon increasing the concentration of ionic surfactants, there is a significant increase in the emission intensity of both the enol forms of DEASAD until premicellar concentration...
February 1, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38287748/evidence-for-the-involvement-of-keratinocyte-derived-microvesicle-particles-in-the-photosensitivity-associated-with-xeroderma-pigmentosum-type-a-deficiency
#39
JOURNAL ARTICLE
Lea Christian, Pranali Manjrekar, Karen M Henkels, Christine M Rapp, Risha Annamraju, Rushabh P Lohade, Shikshita Singh, M Alexandra Carpenter, Saman Khan, Michael G Kemp, Yanfang Chen, Ravi P Sahu, Jeffrey B Travers
Photosensitivity can be due to numerous causes. The photosensitivity associated with deficiency of xeroderma pigmentosum type A (XPA) has been previously shown to be associated with excess levels of the lipid mediator platelet-activating factor (PAF) generated by the keratinocyte. As PAF has been reported to trigger the production of subcellular microvesicle particles (MVP) due to the enzyme acid sphingomyelinase (aSMase), the goal of these studies was to discern if PAF and aSMase could serve as therapeutic targets for the XPA deficiency photosensitivity...
January 29, 2024: Photochemistry and Photobiology
https://read.qxmd.com/read/38282075/far-red-active-unsymmetrical-squaraine-dyes-containing-n-arylated-indoline-donors-for-dye-sensitized-solar-cells
#40
JOURNAL ARTICLE
Avinash P Jadhav, Ambarish Kumar Singh, Rinu Pandya, Kumar Vanka, Kothandam Krishnamoorthy, Nithyanandhan Jayaraj
Squaraine dyes possess sharp far-red active transition with high extinction coefficient and form aggregates on TiO2 surface. Aggregation of dyes on TiO2 has been considered as a detrimental factor for DSSC device performance, which can be controlled by appending alkyl groups to the dye structures. Hence by integrating alkylated (alkyl groups with both in-plane and out-of-plane) aryl group with indoline moiety to make it compatible with other electrolytes and for controlling the dye-aggregation, a series of squaraine acceptor-based dyes SQA4-6 have been designed and synthesized...
January 28, 2024: Photochemistry and Photobiology
journal
journal
23907
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.