Zhao Liu
OBJECT: Previous research has suggested an association between placental tissue abnormalities and the diagnosis of autism spectrum disorder. This study aims to explore the causal relationship between placental weight and autism spectrum disorder. METHODS: This study employed Mendelian randomization analysis to investigate the potential causal relationship between placental weight and autism spectrum disorder. The study design involved two sample populations, with data for the exposed population sourced from previous studies focusing on PW, and data for the outcome population obtained from the Integrative Psychiatric Research and the Psychiatric Genomics Consortium study...
July 6, 2024: Journal of Psychosomatic Research
Alda Troncone, Alessia Piscopo, Angela Zanfardino, Antonietta Chianese, Crescenzo Cascella, Gaetana Affuso, Anna Borriello, Stefano Curto, Assunta Serena Rollato, Veronica Testa, Emanuele Miraglia Del Giudice, Lorenza Magliano, Dario Iafusco
OBJECTIVE: To investigate fear of hypoglycemia (FoH) in parents of children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration. METHOD: In this pre-test/post-test uncontrolled study 364 caregivers of patients with T1D (6-18 years) completed questionnaires measuring sociodemographic characteristics, diabetes-related factors (e.g., type of insulin therapy, glycemic control), and parents' trait anxiety...
July 4, 2024: Journal of Psychosomatic Research
Hayri Can Ozden, S Can Gurel, Necla Ozer, Basaran Demir
OBJECTIVES: Heart rate variability (HRV) reflects the capacity to adapt to internal and environmental changes. Decreased HRV may indicate inadequate adaptive capacity. This study aims to investigate the relationship between the heart and brain's adaptive abilities, both at rest and when negative emotions are stimulated in depression. SUBJECTS AND METHODS: The study included 30 patients (20 female, 10 male) with major depression (mean age = 29.8 ± 7...
June 29, 2024: Journal of Psychosomatic Research
Shijie Guo, Guangwei Qing, Guang Yang
BACKGROUND: This cross-sectional study examines the link between chronic diseases and suicidal thoughts in U.S. adults using 2013-2018 National Health and Nutrition Examination Survey (NHANES) data, aiming to identify potential risk factors for suicidal ideation. METHODS: Using NHANES data, we analyzed the association between various chronic conditions (hypertension, diabetes, asthma, etc.) and suicidal thoughts, employing logistic regression models adjusted for demographics and lifestyle factors...
June 26, 2024: Journal of Psychosomatic Research
Gabrielle Virgili-Gervais, Richard S Henry, Linda Kwakkenbos, Marie-Eve Carrier, Scott Patten, Susan J Bartlett, Luc Mouthon, John Varga, Andrea Benedetti, Brett D Thombs
OBJECTIVE: Symptoms of anxiety increased early in the COVID-19 pandemic among people with systemic sclerosis (SSc) then returned to pre-pandemic levels, but this was an aggregate finding and did not evaluate whether vaccination may have contributed to reduced anxiety symptom levels. We investigated whether being vaccinated for COVID-19 was associated with reduced anxiety symptoms among people with SSc. METHODS: The longitudinal Scleroderma Patient-centered Intervention Network (SPIN) COVID-19 Cohort was launched in April 2020 and included participants from the ongoing SPIN Cohort and external enrollees...
June 23, 2024: Journal of Psychosomatic Research
Maria I Zervou, George N Goulielmos
No abstract text is available yet for this article.
June 23, 2024: Journal of Psychosomatic Research
T A Kuut, L M Buffart, A M J Braamse, F Müller, H Knoop
OBJECTIVE: Cognitive behaviour therapy (CBT) for fatigue in chronic fatigue syndrome (ME/CFS) leads to a significant reduction of fatigue and disability and is available in different treatment delivery formats, i.e. internet-based, individual face-to-face and group face-to-face. The aim of this study was to investigate whether moderation of the effects of CBT by clinically relevant depressive symptoms varies between CBT delivery formats. METHODS: Data from six randomised controlled trials (n = 1084 patients) were pooled...
June 22, 2024: Journal of Psychosomatic Research
Hayami K Koga, Francine Grodstein, David R Williams, Dawn L Demeo, Laura D Kubzansky
OBJECTIVE: Optimism and purpose in life are associated with improved health outcomes. More information is needed on biological mechanisms, including immunosenescence. We investigated if psychological well-being is associated with healthier immunosenescence-related measures including naïve and terminally differentiated CD4+ and CD8+ T cell percentages, CD4+ :CD8+ , and cytomegalovirus (CMV) IgG response. METHODS: Participants were adults over age 50 from the Health and Retirement Study...
June 22, 2024: Journal of Psychosomatic Research
Sebastian Pintea, Paula Maier
OBJECTIVE: This meta-analysis synthesizes research on the impact of cognitive restructuring on chronic pain intensity, aiming to integrate diverse methodologies and findings while evaluating potential moderators. METHODS: Following PRISMA guidelines, we systematically searched multiple databases (PubMed, Web of Science, JSTOR, Sage, Social Science Research Network, PsycArticles, ScienceDirect, and Education Resources Information Center) until July 2023. Studies involving adults (≥18 years) diagnosed with chronic conditions who underwent cognitive restructuring to reduce chronic pain intensity, were included...
June 22, 2024: Journal of Psychosomatic Research
Razak M Gyasi, Hubert Bimpeh Asiedu, Lawrencia Pokuah Siaw, Emmanuel Nyaaba, Emmanuel Affum-Osei, Richard Bruce Lamptey, Faith Muhonja, Dominic Degraft Arthur, Edward Asamoah, Michael Nimoh, Samuel Adu-Gyamfi
OBJECTIVE: Food insecurity has been associated with mobility difficulty (MD) in old age. However, there is a scarcity of research on this topic from low- and middle-income countries, while the bio-psychological factors underlying this association are largely unknown. We investigated the food insecurity-MD link in Ghana and explored how sleep, anxiety, loneliness, and physical activity (PA) mediate the association. METHODS: Community-based, representative cross-sectional data from the Aging, Health, Well-being, and Health-seeking Behavior Study were analyzed (N = 1201; Mage  = 66...
June 22, 2024: Journal of Psychosomatic Research
Caroline Clifford, Raphael Twerenbold, Friederike Hartel, Bernd Löwe, Sebastian Kohlmann
OBJECTIVE: Identifying whether experienced symptom burden in individuals with medical predisposition indicates somatic symptom disorder (SSD) is challenging, given the high overlap in the phenomenology of symptoms within this group. This study aimed to enhance understanding SSD in individuals at risk for heart failure. SUBJECTS AND METHODS: Cross-sectional data from the Hamburg City Health Study was analyzed including randomly selected individuals from the general population of Hamburg, Germany recruited from February 2016 to November 2018...
June 22, 2024: Journal of Psychosomatic Research
Melody S Sadler, Kalila Wash, Lauren M DePaul Trumbach, Terry A Cronan
OBJECTIVE: Fibromyalgia (FM) is a chronic pain condition associated with depression. However, self-efficacy (belief in own ability to manage symptoms) and social support may be protective. This study tested three types of social support (emotional, tangible, and instrumental) for moderation of the mediating effect of self-efficacy on the relationship between FM impact and depression over time. METHODS: Six hundred participants with FM were randomly assigned to no intervention, social support group, or combined self-management and social support...
June 21, 2024: Journal of Psychosomatic Research
Manon Enting, Mariska A C de Jongh, Margot C W Joosen, Marjan Bakker, Daphne T F van der Kruijssen, Ruth E Geuze, Nina Kupper
OBJECTIVE: Surviving physical trauma can have a large impact on one's daily life. Patients are at increased risk for poor physical health, psychological complaints, and problems in role functioning - which is often experienced simultaneously. The present study explores the interconnectedness of physical, psychological, and role functioning during the first two years post-injury, both cross-sectionally and longitudinally from a network perspective. METHODS: 3785 trauma patients (Mage  = 64...
June 19, 2024: Journal of Psychosomatic Research
Nicole Perez, Ning He, Fay Wright, Eileen Condon, Sheri Weiser, Brad Aouizerat
OBJECTIVE: Inflammation is implicated in the pathophysiology of depression and type 2 diabetes (T2D) and is linked to social determinants of health (SDoH) associated with socioeconomic disadvantage. The objective of this review is to identify and map the range of SDoHs associated with inflammation in depression, T2D, or their co-occurrence among women. METHODS: PubMed, CINAHL, PsychINFO, and Web of Science were searched March-July 2023 to identify studies where 1) an SDoH was a predictor or independent variable, 2) depression or T2D was a clinical focus, 3) inflammatory markers were collected, and 4) analysis was specific to women...
June 15, 2024: Journal of Psychosomatic Research
James Overs, Scott Morgan, Pragalathan Apputhurai, Caroline Tuck, Simon R Knowles
OBJECTIVE: To determine the prevalence and associations between anxiety/depression, and gastrointestinal (GI) symptoms across gastroparesis and functional dyspepsia. METHODS: Twenty adult studies were identified through systematic searches of three databases (PubMed, CINAHL and PsycINFO) in September 2023. Meta-analysis was performed to estimate the pooled prevalence rates of anxiety and depression across gastroparesis and functional dyspepsia, and to determine whether the associations of anxiety/depression and gastrointestinal (GI) symptoms differ in gastroparesis versus functional dyspepsia...
June 15, 2024: Journal of Psychosomatic Research
Chu-Chiao Tseng, Yu-Chi Huang, Yu Lee, Chi-Fa Hung, Pao-Yen Lin
OBJECTIVES: This cross-sectional study aimed to characterize the differences of metabolic profiles and atherogenicity between various levels of fatigue severity in patients with major depressive disorder (MDD), and examine the extent to which metabolic abnormality correlates with fatigue severity. METHODS: We recruited 119 patients with MDD and assessed fatigue severity using Krupp's Fatigue Severity Scale. Blood samples were collected to determine plasma levels of fasting glucose, high-density lipoprotein cholesterol (HDL-C), triglycerides, total cholesterol and low-density lipoprotein cholesterol...
June 14, 2024: Journal of Psychosomatic Research
Isabella Raasthøj, Dorte Ejg Jarbøl, Sanne Rasmussen, Sonja Wehberg, Lisa Maria Sele Sætre, Marianne Rosendal, Tina Birgitte Wisbech Carstensen
OBJECTIVE: To compare the prevalence of multiple physical symptoms, coping scores, and associations between multiple physical symptoms and coping in two population-based surveys within a 10-year interval. METHODS: A nationwide study on symptoms and healthcare-seeking, the Danish Symptom Cohort, was carried out in 2012 and repeated in 2022. For each survey, 100,000 randomly selected individuals were invited, and individuals aged 20-64 years were eligible for inclusion...
June 13, 2024: Journal of Psychosomatic Research
Päivi Lappalainen, Katariina Keinonen, Raimo Lappalainen, Sanna Selinheimo, Aki Vuokko, Markku Sainio, Sanna Liesto, Asko Tolvanen, Tiina Paunio
OBJECTIVE: Persistent physical symptoms (PPS) represent a major health problem affecting daily functioning. This RCT aimed to examine whether a guided Internet-based treatment based on acceptance and commitment therapy (ACT) provided additional benefits compared to Treatment as Usual (TAU) in reducing somatic complaints and psychological distress in adults with PPS. METHODS: A total of 103 adults with PPS related to indoor environments, chronic fatigue or both conditions were assigned to receive either either a 14-week intervention (video-based case conceptualization + Internet-based ACT) combined with TAU (iACT + TAU; n = 50) or TAU alone (n = 53)...
June 13, 2024: Journal of Psychosomatic Research
Ulrike Siewert-Markus, Till Ittermann, Johanna Klinger-König, Hans J Grabe, Sylvia Stracke, Henry Völzke, Giovanni Targher, Marcus Dörr, Marcello R P Markus, Philipp Töpfer
BACKGROUND AND AIMS: Childhood maltreatment (CM) is linked to self-reported liver disease in adulthood. However, specific diagnostic entities, e.g., metabolic dysfunction-associated steatotic liver disease (MASLD) as the most frequent chronic liver disease, and sex-differences have previously not been considered. METHODS: Cross-sectional analyses were conducted in 4188 adults from a population-based cohort in Northeastern Germany after excluding individuals with excessive alcohol consumption, cirrhosis, or chronic viral hepatitis...
June 10, 2024: Journal of Psychosomatic Research
Ru Jia, Carol Coupland, Yana Vinogradova, Nadeem Qureshi, Emma Turner, Kavita Vedhara
OBJECTIVE: Research shows that people with a history of mental health conditions were at increased risk of COVID-19 infection, hospitalisation, and mortality. However, the relationship between mental health conditions and COVID-19 vaccine outcomes such as vaccine intention, uptake and vaccine breakthrough is not yet well-understood. METHODS: We conducted a systematic search on the topics of COVID-19 vaccine intentions, vaccine uptake, and vaccine breakthrough, in relation to mental health conditions (e...
June 8, 2024: Journal of Psychosomatic Research
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