journal
https://read.qxmd.com/read/38950507/efficacy-and-safety-of-monoamine-reuptake-inhibitors-in-attention-deficit-hyperactivity-disorder-a-bayesian-network-meta-analysis
#21
REVIEW
Shampa Maji, Archana Mishra, Mathan Kumar Ramasubbu, Debadatta Mohapatra, Rituparna Maiti
The use of first-line drugs in clinical practice for attention deficit hyperactivity disorder (ADHD) is limited by their adverse effects. Many novel monoamine reuptake inhibitors (MRIs) with better safety profiles and comparable efficacy are also being tried for ADHD. This network meta-analysis (NMA) has evaluated the efficacy and safety of MRIs in ADHD. The data was extracted from 31 relevant clinical trials after a literature search on MEDLINE/PubMed, Embase, Scopus, Cochrane databases, and clinical trial registries...
June 27, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/39018710/clinical-segmentation-in-22q11-2-deletion-syndrome-cognitive-impairments-and-additional-genetic-load
#22
JOURNAL ARTICLE
H Schmock, Matt P Stevenson, S Hanebaum, A Vangkilde, A Rosengren, S M Weinsheimer, F Skovby, C Olesen, H Ullum, W F C Baaré, H R Siebner, M Didriksen, T Werge, L Olsen, J R M Jepsen
The 22q11.2 deletion syndrome (22q11.2DS) is associated with high psychiatric morbidity. However, large phenotypic heterogeneity hampers early detection of 22q11.2DS individuals at highest risk. Here, we investigated whether individuals with 22q11.2DS can be subdivided into clinically relevant subgroups based on their severity of cognitive impairments and whether such subgroups differ in polygenic risk. Using a cross-sectional design, we examined the number of lifetime psychiatric diagnoses and polygenic risk scores for schizophrenia in an unselected nationwide biobank cohort of individuals with 22q11...
June 26, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38972264/sleep-hopelessness-and-suicidal-ideation-an-ecological-momentary-assessment-and-actigraphy-study
#23
JOURNAL ARTICLE
Liia M M Kivelä, Willem van der Does, Niki Antypa
Recent research shows that sleep disturbances are linked to increased suicidal ideation. In the present longitudinal cohort study, we used subjective (ecological momentary assessment, EMA) and objective (actigraphy) measures to examine the effects of sleep parameters on next-day suicidal ideation. Further, we examined hopelessness as a mediator between insufficient sleep and increased suicidal ideation. Individuals with current suicidal ideation (N = 82) completed 21 days of EMA and actigraphy to estimate suicidal ideation, hopelessness and sleep parameters...
June 26, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38964089/multimodal-frontal-neuroimaging-markers-predict-longitudinal-craving-reduction-in-abstinent-individuals-with-heroin-use-disorder
#24
JOURNAL ARTICLE
Xinwen Wen, Wenhan Yang, Zhe Du, Jiahao Zhao, Yangding Li, Dahua Yu, Jun Zhang, Jun Liu, Kai Yuan
The variation in improvement among individuals with addiction after abstinence is a critical issue. Here, we aimed to identify robust multimodal markers associated with high response to 8-month abstinence in the individuals with heroin use disorder (HUD) and explore whether the identified markers could be generalized to the individuals with methamphetamine use disorder (MUD). According to the median of craving changes, 53 individuals with HUD with 8-month abstinence were divided into two groups: higher craving reduction and lower craving reduction...
June 26, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/39002531/maladaptive-health-factors-as-potential-mediators-for-the-association-between-posttraumatic-stress-disorder-and-cardiovascular-disease-a-sex-stratified-analysis-in-the-u-s-adult-population
#25
JOURNAL ARTICLE
S K Pierce, K A Reynolds, J L Sommer, R El-Gabalawy, R H Pietrzak, J A Sumner, N Mota
OBJECTIVES: This study examined sex differences for health risk factors as potential mediators in the association between posttraumatic stress disorder (PTSD) and cardiovascular disease (CVD). METHODS: Secondary data from the 2012-2013 National Epidemiological Survey on Alcohol and Related Conditions Wave 3 was used. This cross-sectional survey contains a nationally representative sample of 36,309 U.S. adults (nfemales = 20,447, Mage = 47.16, 95% CI = [46...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38991268/substance-use-disorders-among-armed-forces-veterans-with-gambling-disorder-insights-from-an-inpatient-treatment-sample
#26
JOURNAL ARTICLE
Joshua B Grubbs, Regina Tahk, Heather Chapman, Lauren A Milner, Shane W Kraus
Armed forces veterans are especially prone to experiencing a variety of addictive disorders, including gambling disorder. Even so, gambling disorder in veterans remains understudied generally, and there remain significant gaps in the research literature with regards to how gambling disorder relates to the experience and expression of comorbid substance use disorders. The present work examines the prevalence, presentation, and clinical associations of substance use disorders in U.S. Armed Forces veterans receiving inpatient treatment for gambling disorder...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38981410/estimating-risk-of-loneliness-in-adulthood-using-survey-based-prediction-models-a-cohort-study
#27
JOURNAL ARTICLE
Marko Elovainio, Jaakko Airaksinen, Solja T Nyberg, Jaana Pentti, Laura Pulkki-Råback, Laura Cachon Alonso, Jaana Suvisaari, Tuija Jääskeläinen, Seppo Koskinen, Mika Kivimäki, Christian Hakulinen, Kaisla Komulainen
It is widely accepted that loneliness is associated with health problems, but less is known about the predictors of loneliness. In this study, we constructed a model to predict individual risk of loneliness during adulthood. Data were from the prospective population-based FinHealth cohort study with 3444 participants (mean age 55.5 years, 53.4% women) who responded to a 81-item self-administered questionnaire and reported not to be lonely at baseline in 2017. The outcome was self-reported loneliness at follow-up in 2020...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38972266/the-functional-and-structural-alterations-in-brain-regions-related-to-the-fear-network-model-in-panic-disorder-a-resting-state-fmri-and-t1-weighted-imaging-study
#28
JOURNAL ARTICLE
Ke Shi, Juan Li, Han Zhang, Kai Wang, Cun Li, Ye Xia, Tian Tian, Yuanhao Li, Xiaolong Peng, Yuan Yang
Abnormal functional connectivity (FC) within the fear network model (FNM) has been identified in panic disorder (PD) patients, but the specific local structural and functional properties, as well as effective connectivity (EC), remain poorly understood in PD. The purpose of this study was to investigate the structural and functional patterns of the FNM in PD. Magnetic resonance imaging data were collected from 33 PD patients and 35 healthy controls (HCs). Gray matter volume (GMV), degree centrality (DC), regional homogeneity (ReHo), and amplitude of low-frequency fluctuation (ALFF) were used to identify the structural and functional characteristics of brain regions within the FNM in PD...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38972265/improving-the-reading-ease-of-the-quick-inventory-of-depressive-symptomatology-self-report-qids-sr-development-and-psychometric-properties-of-an-accessible-english-version
#29
JOURNAL ARTICLE
Lucy J Robinson, Richard H McAllister-Williams
Self-report questionnaires are commonly used in depression research with little consideration of their reading ease. This study aimed to increase the reading ease of the commonly-used Quick Inventory of Depressive Symptoms Self Report (QIDS-SR) and assess the impact of the change in wording on the measure's psychometric properties. The study had three phases: 1) Flesh-Kincaid readability statistics of the original and modified wording were compared; 2) a sample of n = 95 participants rated the modified wording for perceived change in meaning and ease of understanding; 3) a second sample of n = 136 participants completed two versions of the QIDS-SR (original, modified, or one of each) alongside the Beck Depression Inventory (BDI)...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38971053/long-term-follow-up-on-patient-attitudes-towards-renewed-ect-a-register-based-cohort-study
#30
JOURNAL ARTICLE
Alexander Kronsell, Axel Nordenskjöld, Ellenor Mittendorfer-Rutz, Mikael Tiger
Electroconvulsive therapy (ECT) is a safe and effective treatment for major depressive disorder (MDD). After receiving ECT for MDD there is a large risk of relapse within the first year. Patient attitudes towards renewed treatment could impact their decisions regarding future therapy. We conducted a nationwide cohort study, using data from Swedish registers. Patients with MDD who received ECT were followed up to six months after the initial ECT-series. We investigated if certain patient and treatment characteristics during the initial treatment were correlated to their attitude towards renewed ECT at the six-month follow-up...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38959825/revealed-masks-facial-mimicry-after-oxytocin-administration-in-forensic-psychopathic-patients
#31
JOURNAL ARTICLE
Ronald J P Rijnders, Anton van Boxtel, Minet de Wied, Jack van Honk, Maaike M Kempes, Peter A Bos
Facial mimicry serves as an evolutionarily rooted important interpersonal communication process that touches on the concepts of socialization and empathy. Facial electromyography (EMG) of the corrugator muscle and the zygomaticus muscle was recorded while male forensic psychopathic patients and controls watched morphed angry or happy facial expressions. We tested the hypothesis that psychopathic patients would show weaker short latency facial mimicry (that is, within 600 ms after stimulus onset) than controls...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38944018/association-between-the-use-of-orexin-receptor-antagonists-and-falls-or-fractures-a-meta-analysis
#32
REVIEW
Guobiao Pan, Lingzhi Ni, Haohao Yan, Lan Yao
Evidence indicates that the use of sedative-hypnotics, including benzodiazepines and z-drugs, is linked to an increased risk of falls and fractures. Nonetheless, the potential exacerbation of this risk by orexin receptor antagonists, which are novel therapeutic agents for treating insomnia, remains uncertain despite their escalating prevalence in clinical practice. We systematically searched four electronic databases from inception to April 17, 2024. In addition, we performed a quality assessment; calculated pooled odds ratios (ORs) to assess the relationship between the use of orexin receptor antagonists and the occurrence of falls or fractures; evaluated heterogeneity across the included studies; and conducted sensitivity analyses...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38944017/optimal-exercise-modality-and-dose-to-improve-depressive-symptoms-in-adults-with-major-depressive-disorder-a-systematic-review-and-bayesian-model-based-network-meta-analysis-of-rcts
#33
REVIEW
Shudong Tian, Zhide Liang, Fanghui Qui, Yingdanni Yu, Chuanzhi Wang, Meng Zhang, Xianliang Wang
Depression is a growing public health concern, and exercise is an adjunctive treatment modality to improve depression, but the optimal form of exercise and the optimal dose are still unclear. This systematic review examined the efficacy of four major types of exercise (aerobic, resistance, mixed, and mind-body) on depression, as well as the dose-response relationship between total and specific exercise and depressive symptoms. We included randomized controlled trials that included participants aged 18 years or older with a diagnosis of major depressive disorder or a depressive symptom score above a threshold as determined by a validated screening measure, implemented one or more exercise therapy groups, and assessed depressive symptoms at baseline and follow-up...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38944016/cognitive-performance-in-adults-with-post-covid-syndrome-results-from-a-german-case-control-study
#34
JOURNAL ARTICLE
Andrea E Zülke, Melanie Luppa, Kerstin Wirkner, Matthias Reusche, Christian Sander, Ronja Büchner, Georg Schomerus, Florian Then Bergh, Jörg Lehmann, A Veronica Witte, Arno Villringer, Samira Zeynalova, Markus Löffler, Christoph Engel, Steffi G Riedel-Heller
Numerous studies on post-COVID syndrome (PCS) describe persisting symptoms of cognitive impairment. Previous studies, however, often investigated small samples or did not assess covariates possibly linked to cognitive performance. We aimed to describe 1) global and domain-specific cognitive performance in adults with PCS, controls with previous SARS-CoV-2 infection and healthy controls, 2) associations of sociodemographics, depressive symptoms, anxiety, fatigue, somatic symptoms and stress with cognitive performance and subjective cognitive decline (SCD), using data of the LIFE-Long-COVID-Study from Leipzig, Germany...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38944015/psychological-profiles-among-people-with-hiv-a-latent-profile-analysis-and-examination-of-the-relationship-with-interpersonal-personality
#35
JOURNAL ARTICLE
Xiaomeng Wang, Shuyu Han, Yan Hu, Lili Zhang, Yukun Zhang, Zhongfang Yang, Xu Zhang, Zhiwen Wang
People living with HIV (PWH) often experience an increased vulnerability to psychiatric disorders as a result of social stigma and discrimination. This study utilized latent profile analysis on a sample of 3040 Chinese PWH to identify distinct psychological profiles. Furthermore, the study investigated the relationships between these profiles with interpersonal personalities, demographic characteristics, social variables and disease-related variables using a three-step regression (R3STEP). The findings from the latent profile analysis revealed that the psychological symptoms of PWH can be categorized into three distinct classes...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38941759/eeg-microstates-are-associated-with-the-improvement-of-obsessive-compulsive-symptoms-after-transcranial-direct-current-stimulation
#36
JOURNAL ARTICLE
Jiayue Cheng, Yang Wang, Yingying Tang, Liangjun Lin, Jian Gao, Zhen Wang
BACKGROUND: Transcranial direct current stimulation (tDCS) is a safe, accessible, and promising therapeutic approach for obsessive-compulsive disorder (OCD). AIMS: This study aimed to evaluate the effect of tDCS on electroencephalography (EEG) microstates and identify potential biomarkers to predict efficacy. METHODS: A total of 24 individuals diagnosed with OCD underwent ten sessions of tDCS targeting the orbitofrontal cortex, while 27 healthy individuals were included as controls...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38941758/social-media-use-and-mental-health-indicators-among-us-adolescents-a-population-based-study
#37
JOURNAL ARTICLE
Sunday Azagba, Todd Ebling, Alperen Korkmaz
Social media use among young people has raised concerns about its potential impact on mental health. However, research is limited regarding whether certain subgroups may be differently affected. This study uses data from the 2022 National Youth Tobacco Survey, a nationally representative sample of middle and high school students aged approximately 11-18 years (n = 23,366). Mental health conditions were assessed using the Patient Health Questionnaire-4, and social media use was categorized by frequency levels...
June 25, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38905762/social-decision-making-in-major-depressive-disorder-a-three-level-meta-analysis
#38
REVIEW
Tao Wang, Jianmin Zeng, Peiru Peng, Qiao Yin
Major Depressive Disorder (MDD) is frequently associated with social dysfunction and impaired decision-making, but its impact on social decisions remains unclear. Thus, we conducted a series of meta-analyses to examine the effects of MDD on key social decision phenomena, including trust, altruistic punishment, and cooperation. We searched Web of Science, PubMed, PsycINFO, and Embase up to December 2023, using Hedges' g to compare social decision-making between MDD patients and healthy controls (HCs). Meta-analytic results showed that MDD patients exhibited a significant reduction in trust (Hedges' g = -0...
June 18, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38936238/exploring-neuroimaging-association-scores-in-adulthood-adhd-and-middle-age-trajectories
#39
JOURNAL ARTICLE
Cibele Edom Bandeira, Eugenio Horacio Grevet, Eduardo Schneider Vitola, Bruna Santos da Silva, Renata Basso Cupertino, Felipe Almeida Picon, Lucas Toshio Ito, Maria Eduarda de Araujo Tavares, Diego Luiz Rovaris, Oliver Grimm, Claiton Henrique Dotto Bau
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder associated with brain differences in children, but not in adults. A combined evaluation of the regional brain differences could improve statistical power and, consequently, allow the detection of possible effects in adults. Thus, our aim is to verify whether Neuroimaging Association Scores (NAS) are associated with adulthood ADHD and clinical trajectories of the disorder in midlife. Clinical and neuroimaging data were collected for 121 subjects with ADHD (mean age: 47...
June 17, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38917724/comparison-of-autogenous-and-reactive-type-obsessive-compulsive-disorders-in-terms-of-clinical-characteristics-a-meta-analysis-study
#40
JOURNAL ARTICLE
Bengu Yucens, Nilgun Oktar Erdogan, Muhammet Gündüz, Selim Tumkaya
Obsessive-compulsive disorder (OCD) has been divided into two subgroups autogenous and reactive types, based on obsessive symptoms. To our knowledge, no meta-analysis study compares sociodemographic and clinical characteristics. Investigation of the differences between the two groups in terms of these basic characteristics may provide information about the accuracy of this classification. This is the first meta-analysis to examine gender, age at onset and some clinical differences between patients with autogenous and reactive OCD...
June 17, 2024: Journal of Psychiatric Research
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