journal
https://read.qxmd.com/read/38994589/out-of-hospital-paramedic-interactions-with-people-living-with-dementia-a-scoping-review
#1
REVIEW
Ming Xuan Han, Linda Ross, Liam Hemingway, David Anderson, Cameron Gosling
BACKGROUND: Dementia encompasses neurodegenerative disorders that account for a global estimated healthcare expenditure of 1.3 trillion US dollars. In Australia, one in 12 people aged ≥65 has a diagnosis of dementia and it is the second leading cause of death. Paramedics play a crucial role in person-centred dementia care, particularly in the community. While consensus has been established on paramedicine's integration into interdisciplinary care teams, there remains a lack of clarity regarding the paramedic role in dementia care...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38984695/pattern-of-heterogeneity-in-normal-brain-ageing-screening-for-mild-cognitive-impairment-and-its-risk-of-progression-with-a-radiomics-model
#2
JOURNAL ARTICLE
Yuting Yan, Xiaodong He, Yuyun Xu, Fanfan Zhao, Jiaxuan Peng, Yuan Shao
PURPOSE: This study aimed to develop a normal brain ageing model based on magnetic resonance imaging and radiomics, therefore identifying radscore, an imaging indicator representing white matter heterogeneity and exploring the significance of radscore in detecting people's cognitive changes. METHODS: Three hundred sixty cognitively normal (CN) subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database and 105 CN subjects from the Parkinson's Progression Markers Initiative database were used to develop the model...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38984694/leisure-time-physical-activity-and-the-incidence-of-atrial-fibrillation-in-senior-adults-a-prospective-cohort-study
#3
JOURNAL ARTICLE
Yunting Mei, Li Huang, Cong Gong, Wenjing Zhao, Ming Gui, Quan Qiu, Zhiwei Wang, Yufeng Chen, Yuanling Xie, Xueqing Cai, Yue-Shuang Yuan, Zhen-Feng Zheng, Yumei Xue, Hai Deng, Xudong Liu
OBJECTIVE: Whether physical activity could reduce the risk of atrial fibrillation (AF) remains unclear. This study was to investigate the relationship of leisure-time physical activity (LTPA) with AF incidence among Chinese older adults. METHODS: A total of 3253 participants aged ≥60 years from the Guangzhou Heart Study were successfully followed between March 2018 and September 2019. LTPA was assessed using a modified Global Physical Activity Questionnaire...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38979796/a-systematic-review-of-fall-prediction-models-for-community-dwelling-older-adults-comparison-between-models-based-on-research-cohorts-and-models-based-on-routinely-collected-data
#4
COMPARATIVE STUDY
Noman Dormosh, Bob van de Loo, Martijn W Heymans, Martijn C Schut, Stephanie Medlock, Natasja M van Schoor, Nathalie van der Velde, Ameen Abu-Hanna
BACKGROUND: Prediction models can identify fall-prone individuals. Prediction models can be based on either data from research cohorts (cohort-based) or routinely collected data (RCD-based). We review and compare cohort-based and RCD-based studies describing the development and/or validation of fall prediction models for community-dwelling older adults. METHODS: Medline and Embase were searched via Ovid until January 2023. We included studies describing the development or validation of multivariable prediction models of falls in older adults (60+)...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38972330/the-mccusker-subjective-cognitive-impairment-inventory-mcsci-a-novel-measure-of-perceived-cognitive-decline
#5
JOURNAL ARTICLE
Hamid R Sohrabi, Brandon E Gavett, Michael Weinborn, Craig P Speelman, Romola S Bucks, Ralph N Martins
BACKGROUND: Subjective cognitive decline (SCD), i.e. self/other-reported concerns on one's cognitive functioning without objective evidence of significant decline, is an indicator of dementia risk. There is little consensus on reliability and validity of the available SCD measures. Therefore, introducing a novel and psychometrically sound measure of SCD is timely. OBJECTIVE: The psychometric properties of a new SCD measure, the McCusker Subjective Cognitive Impairment Inventory-Self-Report (McSCI-S), are reported...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38970550/guideline-summary-assessment-diagnosis-care-and-support-for-people-with-dementia-and-their-carers-scottish-intercollegiate-guidelines-network-sign-guideline-168
#6
JOURNAL ARTICLE
Jennifer Kirsty Burton, Roy L Soiza, Terence J Quinn
The Scottish Intercollegiate Guidelines Network (SIGN) have recently published their guideline SIGN168 on 'Assessment, Diagnosis, Care, and Support for People with Dementia and their Carers'. The guideline makes evidence-based recommendations for best practice in the assessment, care and support of adults living with dementia. Topics featured in this guideline are limited to those prioritised by stakeholders, especially people with lived and living experience, and those not well covered under pre-existing guidance...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38970549/the-use-of-natural-language-processing-for-the-identification-of-ageing-syndromes-including-sarcopenia-frailty-and-falls-in-electronic-healthcare-records-a-systematic-review
#7
JOURNAL ARTICLE
Mo Osman, Rachel Cooper, Avan A Sayer, Miles D Witham
BACKGROUND: Recording and coding of ageing syndromes in hospital records is known to be suboptimal. Natural Language Processing algorithms may be useful to identify diagnoses in electronic healthcare records to improve the recording and coding of these ageing syndromes, but the feasibility and diagnostic accuracy of such algorithms are unclear. METHODS: We conducted a systematic review according to a predefined protocol and in line with Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38970548/strategies-to-improve-end-of-life-decision-making-and-palliative-care-following-hip-fracture-in-frail-older-adults-a-scoping-review
#8
REVIEW
Alexandra Tremblay, Stéphane Pelet, Étienne Belzile, Justine Boulet, Chantal Morency, Norbert Dion, Marc-Aurèle Gagnon, Lynn Gauthier, Amal Khalfi, Mélanie Bérubé
BACKGROUND: Although surgery is the gold standard following a hip fracture, the potential for rehabilitation and survival rates are low in frail older patients. Some patients may derive more benefit from palliative care. The objectives of this review were to identify the available strategies to improve end-of-life decision-making and palliative care for frail patients with hip fractures and to synthetise their level of support. METHODS: We conducted a scoping review of the scientific and grey literature, searching seven databases and websites of associations...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38970547/effects-of-the-discontinuation-of-antihypertensive-treatment-on-neuropsychiatric-symptoms-and-quality-of-life-in-nursing-home-residents-with-dementia-danton-a-multicentre-open-label-blinded-outcome-randomised-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Jonathan M K Bogaerts, Jacobijn Gussekloo, Bianca E M de Jong-Schmit, Saskia Le Cessie, Simon P Mooijaart, Roos C van der Mast, Wilco P Achterberg, Rosalinde K E Poortvliet
BACKGROUND: Based on observational studies and randomised controlled trials (RCTs), the benefit-harm balance of antihypertensive treatment in older adults with dementia is unclear. OBJECTIVE: To assess whether discontinuing antihypertensive treatment reduces neuropsychiatric symptoms (NPSs) and maintains quality of life (QoL) in nursing home residents with dementia. DESIGN: Open-label, blinded-outcome RCT. Randomisation 1:1, stratified by nursing home organisation and baseline NPS...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38970302/implementing-the-information-system-for-older-adult-patients-post-discharge-self-management-a-qualitative-study
#10
JOURNAL ARTICLE
Dorothy Yingxuan Wang, Eliza Lai-Yi Wong, Annie Wai-Ling Cheung, Zoe Pui-Yee Tam, Kam-Shing Tang, Eng-Kiong Yeoh
BACKGROUND: Discharging older adult patients from the hospital poses risks due to their vulnerable conditions, complex instructions and limited health literacy. Insufficient information about medication side effects adds to patient concerns. To address this, a post-discharge information summary system was developed. While it has shown positive impacts, concerns exist regarding implementation fidelity. OBJECTIVE: This study employed a theory-driven approach to understand health providers' perspectives on effective implementation...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38965033/towards-an-explanation-for-unexplained-dizziness-in-older-people
#11
JOURNAL ARTICLE
Patricia Castro, Richard Ibitoye, Toby Ellmers, Diego Kaski, Qadeer Arshad, Adolfo M Bronstein
BACKGROUND: Subjective unsteadiness or dizziness, usually without increase in body sway, is common in older people. The absence of mechanistic understanding of such symptoms renders clinical management difficult. Here, we explore the mechanisms behind such idiopathic dizziness (ID), focusing on postural control abnormalities. METHODS: Thirty patients with ID and 30 age-matched controls stood on a moving platform. Platform oscillations were randomly delivered at different velocities (from 0 to 0...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38965032/the-interrelationship-between-multiple-long-term-conditions-mltc-and-delirium-a-scoping-review
#12
REVIEW
Sarah Joanna Richardson, Alexandria Danielle Cropp, Samantha Wilhelmina Ellis, Jake Gibbon, Avan Aihie Sayer, Miles David Witham
INTRODUCTION: Delirium and multiple long-term conditions (MLTC) share numerous risk factors and have been shown individually to be associated with adverse outcomes following hospitalisation. However, the extent to which these common ageing syndromes have been studied together is unknown. This scoping review aims to summarise our knowledge to date on the interrelationship between MLTC and delirium. METHODS: Searches including terms for delirium and MLTC in adult human participants were performed in PubMed, EMBASE, Medline, Psycinfo and CINAHL...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38965031/treat-to-target-or-high-intensity-statin-treatment-in-older-adults-with-coronary-artery-disease-a-post-hoc-analysis-of-the-lodestar-trial
#13
RANDOMIZED CONTROLLED TRIAL
Seung-Jun Lee, Jin-Bae Lee, Tae-Hyun Yang, Woong Chol Kang, Jong-Young Lee, Yong-Joon Lee, Sung-Jin Hong, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Bum-Kee Hong, Donghoon Choi, Junghan Yoon, Yangsoo Jang, Myeong-Ki Hong
BACKGROUND: The optimal statin treatment strategy that is balanced for both efficacy and safety has not been clearly determined in older adults with coronary artery disease (CAD). METHODS: In the post hoc analysis of the LODESTAR (low-density lipoprotein cholesterol-targeting statin therapy versus intensity-based statin therapy in patients with coronary artery disease) trial, the impact between a treat-to-target strategy versus a high-intensity statin therapy strategy was compared in older adults (aged 75 years or older)...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38954435/detection-of-anxiety-symptoms-and-disorders-in-older-adults-a-diagnostic-accuracy-systematic-review
#14
JOURNAL ARTICLE
Kayla Atchison, Pauline Wu, Leyla Samii, Michael Walsh, Zahinoor Ismail, Andrea Iaboni, Zahra Goodarzi
BACKGROUND: Anxiety symptoms and disorders are common in older adults and often go undetected. A systematic review was completed to identify tools that can be used to detect anxiety symptoms and disorders in community-dwelling older adults. METHODS: MEDLINE, Embase and PsycINFO were searched using the search concepts anxiety, older adults and diagnostic accuracy in March 2023. Included articles assessed anxiety in community-dwelling older adults using an index anxiety tool and a gold standard form of anxiety assessment and reported resulting diagnostic accuracy outcomes...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38952188/temporal-dynamics-of-depressive-symptoms-and-cognitive-decline-in-the-oldest-old-dynamic-time-warp-analysis-of-the-leiden-85-plus-study
#15
JOURNAL ARTICLE
Abe J C van der Slot, Anne Suzanne Bertens, Stella Trompet, Simon P Mooijaart, Jacobijn Gussekloo, Frederiek van den Bos, Erik J Giltay
BACKGROUND: The prevalence of depressive symptoms and cognitive decline increases with age. We investigated their temporal dynamics in individuals aged 85 and older across a 5-year follow-up period. METHODS: Participants were selected from the Leiden 85-plus study and were eligible if at least three follow-up measurements were available (325 of 599 participants). Depressive symptoms were assessed at baseline and at yearly assessments during a follow-up period of up to 5 years, using the 15-item Geriatric Depression Scale (GDS-15)...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38952187/determinants-influencing-the-implementation-of-multifactorial-falls-risk-assessment-and-multidomain-interventions-in-community-dwelling-older-people-a-systematic-review
#16
JOURNAL ARTICLE
Sara Vandervelde, Natalie Van den Bosch, Ellen Vlaeyen, Bernadette Dierckx de Casterlé, Johan Flamaing, Goedele Belaen, Krizia Tuand, Thomas Vandendriessche, Koen Milisen
BACKGROUND: Multifactorial falls risk assessment and multidomain interventions are recommended by the World guidelines for falls prevention and management. To successfully implement these interventions, it is important to understand determinants influencing the implementation. METHODS: A literature search was conducted for this systematic review on the 3 December 2021 and updated on the 3 April 2023 in five databases: PubMed (including MEDLINE), EMBASE (via Embase...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38952186/a-world-wide-study-on-delirium-assessments-and-presence-of-protocols
#17
JOURNAL ARTICLE
Peter Nydahl, Keibun Liu, Giuseppe Bellelli, Julie Benbenishty, Mark van den Boogaard, Gideon Caplan, Chi Ryang Chung, Muhammed Elhadi, Mohan Gurjar, Gabi Heras-La Calle, Magdalena Hoffmann, Marie-Madlen Jeitziner, Karla Krewulak, Tanya Mailhot, Alessandro Morandi, Ricardo Kenji Nawa, Esther S Oh, Marie O Collet, Maria Carolina Paulino, Heidi Lindroth, Rebecca von Haken
BACKGROUND: Delirium is a common complication of older people in hospitals, rehabilitation and long-term facilities. OBJECTIVE: To assess the worldwide use of validated delirium assessment tools and the presence of delirium management protocols. DESIGN: Secondary analysis of a worldwide one-day point prevalence study on World Delirium Awareness Day, 15 March 2023. SETTING: Cross-sectional online survey including hospitals, rehabilitation and long-term facilities...
July 2, 2024: Age and Ageing
https://read.qxmd.com/read/38941119/effectiveness-of-non-pharmacological-interventions-delivered-at-home-for-urinary-and-faecal-incontinence-with-homebound-older-people-systematic-review-of-randomised-controlled-trials
#18
JOURNAL ARTICLE
Jackie Buck, Julia Fromings Hill, Rachael Collins, Joanne Booth, Jane Fleming
INTRODUCTION: Incontinence is a common, distressing condition, most prevalent in older people. There is an unmet need for effective interventions to support continence. This review focuses on non-pharmacological interventions to reduce incontinence among homebound older people. Aim: to identify interventions with potential to be delivered by care workers, nurses or family members in a person's home. METHODS: Multiple databases were searched until 15 September 2023 for randomised controlled trials reporting home-based interventions for incontinence for older people (≥65 years) living at home...
June 1, 2024: Age and Ageing
https://read.qxmd.com/read/38941118/impact-of-care-recipient-relationship-type-on-quality-of-life-in-caregivers-of-older-adults-with-dementia-over-time
#19
JOURNAL ARTICLE
Aiping Lai Kin, Lauren E Griffith, Ayse Kuspinar, Jenna Smith-Turchyn, Julie Richardson
BACKGROUND: Dementia caregiving is a dynamic and multidimensional process. To gain a comprehensive understanding of informal caregiving for people living with dementia (PLWD), it is pivotal to assess the quality of life (QoL) of informal caregivers. OBJECTIVE: To evaluate whether the care-recipient relationship type predicts changes in the QoL of informal caregivers of PLWD over a two-year period. METHODS: This was a secondary analysis of longitudinal data...
June 1, 2024: Age and Ageing
https://read.qxmd.com/read/38941117/epigenetic-age-acceleration-and-the-risk-of-frailty-and-persistent-activities-of-daily-living-adl-disability
#20
JOURNAL ARTICLE
Aung Zaw Zaw Phyo, Sara E Espinoza, Anne M Murray, Peter D Fransquet, Jo Wrigglesworth, Robyn L Woods, Joanne Ryan
BACKGROUND: Epigenetic ageing is among the most promising ageing biomarkers and may be a useful marker of physical function decline, beyond chronological age. This study investigated whether epigenetic age acceleration (AA) is associated with the change in frailty scores over 7 years and the 7-year risk of incident frailty and persistent Activities of Daily Living (ADL) disability among 560 Australians (50.7% females) aged ≥70 years. METHODS: Seven AA indices, including GrimAge, GrimAge2, FitAge and DunedinPACE, were estimated from baseline peripheral-blood DNA-methylation...
June 1, 2024: Age and Ageing
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