Violeta Raverdy, Federica Tavaglione, Estelle Chatelain, Robert Caiazzo, Chiara Saponaro, Guillaume Lassailly, Helene Verkindt, Gregory Baud, Camille Marciniak, Mikael Chetboun, Naima Oukhouya-Daoud, Viviane Gnemmi, Emmanuelle Leteurtre, Alain Duhamel, Mathurin Philippe, Guillemette Marot, Stefano Romeo, François Pattou
BACKGROUND & AIMS: The value of non-invasive tests for monitoring the resolution of significant liver fibrosis after treatment is poorly investigated. We compared the performances of six non-invasive tests to predict the resolution of significant fibrosis after bariatric surgery. METHODS: Participants were individuals with obesity submitted to needle liver biopsy at the time of bariatric surgery, and 12 and/or 60 months after surgery. We calculated the fibrosis-4 index (FIB-4), NAFLD fibrosis score (NFS), AST to platelet ratio index (APRI), Hepatic fibrosis score (HFS), Fibrosis NAFLD index (FNI), and Liver risk score (LRS) at each time point, and compared their performances for predicting significant fibrosis (F ≥ 2) and its resolution following surgery...
January 12, 2024: Metabolism: Clinical and Experimental