journal
Journals Journal of Agricultural and Fo...

Journal of Agricultural and Food Chemistry

https://read.qxmd.com/read/38394631/quinolizidine-alkaloids-and-isoflavones-from-the-herb-of-thermopsis-lupinoides-and-their-antiviral-antifungal-and-insecticidal-activities
#1
JOURNAL ARTICLE
Tong Zhang, Cai-Yan Tian, Ji Zhang, Qiao An, Ping Yi, Chun-Mao Yuan, Zhong-Kai Zhang, Li-Hua Zhao, Xiao-Jiang Hao, Zhan-Xing Hu
As part of our ongoing investigation of natural bioactive substances from the genus Thermopsis of the tribe Fabaceae for agricultural protection, the chemical constituents of the herb Thermopsis lupinoides were systematically investigated, which led to the isolation of 39 quinolizidine alkaloids (QAs) ( 1 - 39 ), including 14 new QAs ( 1 - 14 ) and 14 isoflavones ( 40 - 53 ). Their structures were elucidated through comprehensive spectroscopic data analysis (IR, UV, NMR, HRESIMS), ECD calculations, and X-ray crystallography...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38394628/unraveling-the-genetic-adaptations-in-cell-surface-composition-and-transporters-of-lactiplantibacillus-plantarum-for-enhanced-acid-tolerance
#2
JOURNAL ARTICLE
Jiang Zhu, Yuwei Sun, Shiyao Zhang, Hong Li, Zhijia Liu, Xuebo Liu, Junjie Yi
This study employed adaptive laboratory evolution to improve the acid tolerance of Lactiplantibacillus plantarum , a vital strain in food fermentation and a potential probiotic. Phenotype and genomic analyses identified the overexpression of stress response proteins, ATP synthases, and transporters as pivotal in conferring acid tolerance to the evolved strains. These adaptations led to a shorter lag phase, improved survival rates, and higher intracellular pH values compared to the wild-type strain under acid stress conditions...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38394621/petrol-note-in-riesling-1-1-6-trimethyl-1-2-dihydronaphthalene-tdn-selectively-activates-human-odorant-receptor-or8h1
#3
JOURNAL ARTICLE
Franziska Haag, Tim Frey, Lena Ball, Sandra Hoffmann, Dietmar Krautwurst
Grapevine ( Vitis vinifera ) is one of the most important perennial fruit plants. The variety Riesling stands out by developing a characteristic petrol-like odor note during aging, elicited by the aroma compound 1,1,6-trimethyl-1,2-dihydronaphthalene (TDN). The UV-dependent TDN contents differ largely among Rieslings grown in the northern versus the southern hemisphere. Highest TDN concentrations were found in Australian Rieslings, where TDN is a scoring ingredient. In contrast, in Rieslings from Europe, for example, TDN may be a tending cause of rejection...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38394368/evaluating-the-atypical-aging-potential-development-in-sparkling-wines-can-be-achieved-by-assessing-the-base-wines-at-the-end-of-the-alcoholic-fermentation
#4
JOURNAL ARTICLE
Simone Delaiti, Tiziana Nardin, Tomas Roman, Stefano Pedò, Roberto Larcher
Traditional sparkling wine production is a lengthy and costly process, involving a double fermentation step and a period of aging sur lie ; thus, monitoring quality during the key manufacturing stages is crucial. The effects of the second fermentation on the development of 2-aminoacetophenone (AAP), the main marker of the atypical aging (ATA) defect, were investigated on 55 base wines (BWs) and corresponding sparkling wines (SWs) produced in an experimental winery. While the AAP content of the SWs was observed to be higher than the BWs, it was found that an artificial aging test carried out on the BWs could be a good predictor of ATA development in SWs...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38394028/fermentation-of-texturized-pea-protein-in-combination-with-proteases-for-aroma-development-in-meat-analogues
#5
JOURNAL ARTICLE
Mónica Flores, Daniel Comes, Amparo Gamero, Carmela Belloch
The potential use of texturized pea protein in meat analogues was investigated by comparing the effects of fermentation on pea and myofibrillar pork proteins in a model system including additives, microbial starters, and proteases. Model fermentation was controlled for 15 days by a pH decrease and microbial count and free amino acid increase. Besides, volatile production and sensory properties were evaluated at the end of fermentation. Protein type affected free amino acid generation and volatile profile. Models supplemented with proteases showed an increase in amino-acid-derived compounds (branched aldehydes and alcohols) and fruity odor notes...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38393993/atypical-plant-mirna-cal-mir2911-robust-stability-against-food-digestion-and-specific-promoting-effect-on-bifidobacterium-in-mice
#6
JOURNAL ARTICLE
Qin Xu, Jianing Wang, Yi Zhang, Ying Li, Xinshu Qin, Yirao Xin, Yinglei Li, Ke Xu, Xingbin Yang, Xingyu Wang
Previous studies showed that cal-miR2911, featuring an atypical biogenesis, could target genes of virus and in turn inhibit virus replication. Given its especial sequence motif and cross-kingdom potential, the stability of miR2911 under digestive environment and its impact on intestinal microbes in mice were examined. The results showed that miR2911 was of considerable stability during oral, gastric, and intestinal digestion. The coingested food matrix enhanced its stability in the gastric phase, contributing to the existence of miR2911 in mouse intestines...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38393978/2-fucosyllactose-promotes-colonization-of-akkermansia-muciniphila-and-prevents-colitis-in-vitro-and-in-mice
#7
JOURNAL ARTICLE
Xiaoxia Liu, Bowei Zhang, Yunhui Zhang, Wanhua Li, Jia Yin, Aiying Shi, Jin Wang, Shuo Wang
Akkermansia muciniphila is a potential candidate for ulcerative colitis prevention. Considering that it utilizes 2'-fucosyllactose (2'FL) for growth, 2'FL can be used to enrich the abundance of A. muciniphila in feces. However, whether the crosswalk between 2'FL and A. muciniphila can promote the intestinal colonization of A. muciniphila remains unclear. In this study, we explored the effect and the underlying mechanism of 2'FL on the colonization of A. muciniphila in vitro and in vivo as well as its alleviating effect on colitis...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38393975/confining-the-growth-of-agnps-onto-epigallocatechin-gallate-decorated-zein-nanoparticles-for-constructing-potent-protein-based-antibacterial-nanocomposites
#8
JOURNAL ARTICLE
Like Wang, Xiaonan Huang, Xiaoxuan Cao, Fuzhen Zhou, Bo Liu, Shuheng Wei, Xia Liu, Xiaoquan Yang, Shouwei Yin
Sliver nanoparticles (AgNPs) have attracted tremendous interest as an alternative to commercially available antibiotics due to their low microbial resistance and broad-spectrum antimicrobial activity. However, AgNPs are highly reactive and unstable and are susceptible to fast oxidation. Synthesizing stable and efficient AgNPs using green chemistry principles remains a major challenge. To address this issue, we establish a facile route to form AgNP-doped zein nanoparticle core-satellite superstructures with ultralow minimum bactericidal concentration (MBC)...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38393752/phytochemical-profile-bioactive-properties-and-se-speciation-of-se-biofortified-red-radish-raphanus-sativus-green-pea-pisum-sativum-and-alfalfa-medicago-sativa-microgreens
#9
JOURNAL ARTICLE
Marilyn M García-Tenesaca, Mercè Llugany, Roberto Boada, María-Jesús Sánchez-Martín, Manuel Valiente
The impact of selenium (Se) enrichment on bioactive compounds and sugars and Se speciation was assessed on different microgreens (green pea, red radish, and alfalfa). Sodium selenite and sodium selenate at a total concentration of 20 μM (1:1) lead to a noticeable Se biofortification (40-90 mg Se kg-1 DW). In green pea and alfalfa, Se did not negatively impact phenolics and antioxidant capacity, while in red radish, a significant decrease was found. Regarding photosynthetic parameters, Se notably increased the level of chlorophylls and carotenoids in green pea, decreased chlorophyll levels in alfalfa, and had no effect on red radish...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38391237/evidence-of-cross-kingdom-gene-regulation-by-plant-micrornas-and-possible-reasons-for-inconsistencies
#10
REVIEW
Tielong Xu, Yating Zhu, Ziqi Lin, Jinyue Lei, Longxue Li, Weifeng Zhu, Diyao Wu
The debate on whether cross-kingdom gene regulation by orally acquired plant miRNAs is possible has been ongoing for nearly 10 years without a conclusive answer. In this study, we categorized plant miRNAs into different groups, namely, extracellular vesicle (EV)-borne plant miRNAs, extracted plant miRNAs, herbal decoction-borne plant miRNAs, synthetic plant miRNA mimics, and plant tissue/juice-borne plant miRNAs. This categorization aimed to simplify the analysis and address the question more specifically. Our evidence suggests that EV-borne plant miRNAs, extracted plant miRNAs, herbal decoction-borne plant miRNAs, and synthetic plant miRNA mimics consistently facilitate cross-kingdom gene regulation...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38390847/phthalates-induce-neurotoxicity-by-disrupting-the-mfn2-perk-axis-mediated-endoplasmic-reticulum-mitochondria-interaction
#11
JOURNAL ARTICLE
Yi Zhao, Yuan-Hang Chang, Hao-Ran Ren, Ming Lou, Fu-Wei Jiang, Jia-Xin Wang, Ming-Shan Chen, Shuo Liu, Yu-Sheng Shi, Hong-Mei Zhu, Jin-Long Li
Di-(2-ethylhexyl) phthalate (DEHP), as the most common phthalate, has been extensively used as a plasticizer to improve the plasticity of agricultural products, which pose severe harm to human health. Mitochondrial dynamics and endoplasmic reticulum (ER) homeostasis are indispensable for maintaining mitochondria-associated ER membrane (MAM) integrity. In this study, we aimed to explore the effect of DEHP on the nervous system and its association with the ER-mitochondria interaction. Here, we showed that DEHP caused morphological changes, motor deficits, cognitive impairments, and blood-brain barrier disruption in the brain...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38390707/-4-z-lachnophyllum-lactone-a-metabolite-with-phytotoxic-and-antifungal-activity-against-pests-affecting-mediterranean-agriculture-a-new-versatile-and-easy-scalable-parallel-synthesis
#12
JOURNAL ARTICLE
Gabriele Soriano, Davide Arnodo, Marco Masi, Mónica Fernández-Aparicio, Blanca B Landa, Concepción Olivares-García, Alessio Cimmino, Cristina Prandi
A methodology for the total and modulable synthesis of (4 Z )-lachnophyllum lactone ( 1 ), on a gram scale, is reported for the first time. The present work started with the design of a retrosynthetic pathway for the target compound, with the key step identified in Pd-Cu bimetallic cascade cross-coupling cyclization. (4 Z )-Lachnophyllum lactone ( 1 ) is an acetylenic furanone previously isolated, in a low amount, from the organic extract of the autotrophic weed Conyza bonariensis . Tested against the stem parasitic weed Cuscuta campestris in a seedling growth bioassay, (4 Z )-lachnophyllum lactone ( 1 ) showed almost 85% of inhibitory activity up to 0...
February 23, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38389392/combining-metabolic-engineering-and-lipid-droplet-assembly-to-achieve-campesterol-overproduction-in-saccharomyces-cerevisiae
#13
JOURNAL ARTICLE
Zhijie Qin, Yunliang Zhang, Song Liu, Weizhu Zeng, Jingwen Zhou, Sha Xu
Campesterol is a kind of important functional food additive. Therefore, stable and efficient campesterol biosynthesis is significant. Herein, we first knocked out the sterol 22-desaturase gene in Saccharomyces cerevisiae and expressed sterol Δ7-reductase from Pangasianodon hypophthalmus , obtaining a strain that produced 6.6 mg/L campesterol. Then, the modular expression of campesterol synthesis enzymes was performed, and a campesterol titer of 88.3 mg/L was achieved. Because campesterol is a lipid-soluble macromolecule, we promoted lipid droplet formation by exploring regulatory factors, and campesterol production was improved to 169...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38388372/design-synthesis-and-biological-activities-of-novel-coumarin-derivatives-as-pesticide-candidates
#14
JOURNAL ARTICLE
Henan Ma, Kaihua Wang, Beibei Wang, Ziwen Wang, Yuxiu Liu, Qingmin Wang
Food security is an important issue in the 21st century; preventing and controlling crop diseases and pests are the key to solve this problem. The creation of new pesticides based on natural products is an important and effective method. Herein, coumarins were selected as parent structures, and a series of their derivatives were designed, synthesized, and evaluated for their antiviral activities, fungicidal activities, and insecticidal activities. We found that coumarin derivatives exhibited good to excellent antiviral activities against tobacco mosaic virus (TMV)...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38388339/comparative-study-of-the-effects-of-dietary-free-and-bound-n%C3%AE%C2%B5-carboxymethyllysine-on-gut-microbiota-and-intestinal-barrier
#15
JOURNAL ARTICLE
Xiaojin Yuan, Juan Liu, Chenxi Nie, Qingyu Ma, Chaoqi Wang, Huicui Liu, Zhifei Chen, Min Zhang, Juxiu Li
Nε-carboxymethyllysine (CML) is produced by a nonenzymatic reaction between reducing sugar and ε-amino group of lysine in food and exists as free and bound forms with varying digestibility and absorption properties in vivo , causing diverse interactions with gut microbiota. The effects of different forms of dietary CML on the gut microbiota and intestinal barrier of mice were explored. Mice were exposed to free and bound CML for 12 weeks, and colonic morphology, gut microbiota, fecal short-chain fatty acids (SCFAs), intestinal barrier, and receptor for AGE (RAGE) signaling cascades were measured...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38386916/naturally-occurring-asterric-acid-analogs-chemistry-and-biology
#16
REVIEW
Yue Tan, Lin Chen, Gang Ding
Asterric acid and its analogs belong to diphenyl ethers (DPEs) with multiple substitutions on A/B aromatic rings. This member of DPEs originates from the polyketide pathway and displays a wide range of biological effects. Though the structures of asterric acid analogs are not complex, there were only more than 50 asterric acid analogs found in nature from 1960 to 2023. In this review, the structures, bioactivities, and biosynthesis of asterric acid analogs are summarized. More importantly, the empirical rule about the shielding effect of B-ring on H-6 is suggested, and this provides a convenient and useful way to analyze the NMR spectral data of asterric acid analogs, based on which the chemical shift values of the A-ring in some asterric acid analogs are revised...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38386875/novel-perspective-on-mechanism-in-muscle-growth-inhibited-by-ochratoxin-a-associated-with-ferroptosis-model-of-juvenile-grass-carp-ctenopharyngodon-idella-in-vivo-and-in-vitro-trials
#17
JOURNAL ARTICLE
Piao Zhao, Lu Zhang, Lin Feng, Wei-Dan Jiang, Pei Wu, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Xiao-Qiu Zhou
Ochratoxin A (OTA) is a common mycotoxin in food and feed that seriously harms human and animal health. This study investigated the effect of OTA on the muscle growth of juvenile grass carp ( Ctenopharyngodon idella ) and its possible mechanism in vitro. Our results have the following innovative findings: (1) Dietary OTA increased the expression of increasing phase I metabolic enzymes and absorbing transporters while reducing the expression of efflux transporters, thereby increasing their residue in muscles; (2) OTA inhibited the expressions of cell cycle and myogenic regulatory factors (MyoD, MyoG, and MyHC) and induced ferroptosis by decreasing the mRNA and protein expressions of FTH, TFR1, GPX4, and Nrf2 both in vivo and in vitro; and (3) the addition of DFO improved OTA-induced ferroptosis of grass carp primary myoblasts and promoted cell proliferation, while the addition of AKT improved OTA-inhibited myoblast differentiation and fusion, thus inhibiting muscle growth...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38386648/decoding-molecular-mechanism-underlying-human-olfactory-receptor-or8d1-activation-by-sotolone-enantiomers
#18
JOURNAL ARTICLE
Juan Wang, Danqing Wang, Mingquan Huang, Baoguo Sun, Fazheng Ren, Jihong Wu, Jinglin Zhang, Hehe Li, Xiaotao Sun
Sotolone, a chiral compound, plays an important role in the food industry. Herein, ( R )-/( S )-sotolone were separated to determine their odor characteristics and thresholds in air ( R -form: smoky, burned, herb, and green aroma, 0.0514 μg/m3 ; S -form: sweet, milk, acid, and nutty aroma, 0.0048 μg/m3 ). OR8D1 responses to ( R )-/( S )-sotolone were detected in a HEK293 cell-based luminescence assay. ( S )-Sotolone was a more potent agonist than ( R )-sotolone (EC50 values of 84.98 ± 1.05 and 167...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38386626/characterization-of-a-gh20-%C3%AE-n-acetylhexosaminidase-from-flavobacterium-algicola-suitable-to-synthesize-lacto-n-triose-ii
#19
JOURNAL ARTICLE
Chengqiang Li, Zhuoning Cao, Hong Jiang, Francesco Secundo, Xiangzhao Mao
β- N -Acetylhexosaminidases have attracted much attention in the enzymatic synthesis of lacto- N -triose II (LNT2) as a backbone precursor of human milk oligosaccharides (HMOs). In this study, a novel glycoside hydrolase (GH) 20 family β- N -acetylhexosaminidase, FlaNag2353, from Flavobacterium algicola was biochemically characterized and applied to synthesize LNT2. FlaNag2353 displayed optimal activity to p -nitrophenyl N -acetyl-β-d-glucosaminide ( p NP-GlcNAc) at 40 °C and pH 8.0. In addition to its excellent hydrolysis activity toward p NP-GlcNAc and chitooligosaccharides, FlaNag2353 showed trans-glycosylation activity...
February 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38386432/optimizing-the-biosynthesis-of-dihydroquercetin-from-naringenin-in-saccharomyces-cerevisiae
#20
JOURNAL ARTICLE
Yuyang Pan, Zhibo Yan, Songlyu Xue, Chufan Xiao, Guangjian Li, Wenyong Lou, Mingtao Huang
Dihydroquercetin (DHQ), known for its varied physiological benefits, is widely used in the food, chemical, and pharmaceutical industries. However, the efficiency of the DHQ synthesis is significantly limited by the substantial accumulation of intermediates during DHQ biosynthesis. In this study, DHQ production was achieved by integrating genes from various organisms into the yeast chromosome for the expression of flavanone-3-hydroxylase (F3H), flavonoid-3'-hydroxylase, and cytochrome P450 reductase. A computer-aided protein design approach led to the development of optimal F3H mutant P221A, resulting in a 1...
February 22, 2024: Journal of Agricultural and Food Chemistry
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